The role of protein dynamics in the evolution of new enzyme function von Campbell, Eleanor, Kaltenbach, Miriam, Correy, Galen J, Carr, Paul D, Porebski, Benjamin T, Livingstone, Emma K, Afriat-Jurnou, Livnat, Buckle, Ashley M, Weik, Martin, Hollfelder, Florian, Tokuriki, Nobuhiko, Jackson, Colin J

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Ancestral Protein Reconstruction Yields Insights into Adaptive Evolution of Binding Specificity in Solute-Binding Proteins von Clifton, Ben E., Jackson, Colin J.

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LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia von Henneberger, Christian, Bard, Lucie, Panatier, Aude, Reynolds, James P., Kopach, Olga, Medvedev, Nikolay I., Minge, Daniel, Herde, Michel K., Anders, Stefanie, Kraev, Igor, Heller, Janosch P., Rama, Sylvain, Zheng, Kaiyu, Jensen, Thomas P., Sanchez-Romero, Inmaculada, Jackson, Colin J., Janovjak, Harald, Ottersen, Ole Petter, Nagelhus, Erlend Arnulf, Oliet, Stephane H.R., Stewart, Michael G., Nägerl, U. Valentin, Rusakov, Dmitri A.

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Physiology, Biochemistry, and Applications of F420- and Fo-Dependent Redox Reactions von Greening, Chris, Ahmed, F Hafna, Mohamed, A Elaaf, Lee, Brendon M, Pandey, Gunjan, Warden, Andrew C, Scott, Colin, Oakeshott, John G, Taylor, Matthew C, Jackson, Colin J

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Sensing and signaling of oxidative stress in chloroplasts by inactivation of the SAL1 phosphoadenosine phosphatase von Chan, Kai Xun, Mabbitt, Peter D., Phua, Su Yin, Mueller, Jonathan W., Nisar, Nazia, Gigolashvili, Tamara, Stroeher, Elke, Grassl, Julia, Arlt, Wiebke, Estavillo, Gonzalo M., Jackson, Colin J., Pogson, Barry J.

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Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme von Tokuriki, Nobuhiko, Jackson, Colin J., Afriat-Jurnou, Livnat, Wyganowski, Kirsten T., Tang, Renmei, Tawfik, Dan S.

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Laboratory evolution of protein conformational dynamics von Campbell, Eleanor C, Correy, Galen J, Mabbitt, Peter D, Buckle, Ashley M, Tokuriki, Nobuhiko, Jackson, Colin J

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Structural and functional characterization of a putative de novo gene in Drosophila von Lange, Andreas, Patel, Prajal H., Heames, Brennen, Damry, Adam M., Saenger, Thorsten, Jackson, Colin J., Findlay, Geoffrey D., Bornberg-Bauer, Erich

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A Comprehensive Phylogenetic Analysis of the Serpin Superfamily von Spence, Matthew A, Mortimer, Matthew D, Buckle, Ashley M, Minh, Bui Quang, Jackson, Colin J

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Reconstructing a Missing Link in the Evolution of a Recently Diverged Phosphotriesterase by Active-Site Loop Remodeling von Afriat-Jurnou, Livnat, Jackson, Colin J, Tawfik, Dan S

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Evolution of cyclohexadienyl dehydratase from an ancestral solute-binding protein von Clifton, Ben E., Kaczmarski, Joe A., Carr, Paul D., Gerth, Monica L., Tokuriki, Nobuhiko, Jackson, Colin J.

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Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity von Izoré, Thierry, Candace Ho, Y. T., Kaczmarski, Joe A., Gavriilidou, Athina, Chow, Ka Ho, Steer, David L., Goode, Robert J. A., Schittenhelm, Ralf B., Tailhades, Julien, Tosin, Manuela, Challis, Gregory L., Krenske, Elizabeth H., Ziemert, Nadine, Jackson, Colin J., Cryle, Max J.

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Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme von Kaczmarski, Joe A., Mahawaththa, Mithun C., Feintuch, Akiva, Clifton, Ben E., Adams, Luke A., Goldfarb, Daniella, Otting, Gottfried, Jackson, Colin J.

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Conformational Tinkering Drives Evolution of a Promiscuous Activity through Indirect Mutational Effects von Yang, Gloria, Hong, Nansook, Baier, Florian, Jackson, Colin J, Tokuriki, Nobuhiko

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Overcoming insecticide resistance through computational inhibitor design von Correy, Galen J., Zaidman, Daniel, Harmelin, Alon, Carvalho, Silvia, Mabbitt, Peter D., Calaora, Viviane, James, Peter J., Kotze, Andrew C., Jackson, Colin J., London, Nir

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Structural and evolutionary approaches to the design and optimization of fluorescence-based small molecule biosensors von Kaczmarski, Joe A, Mitchell, Joshua A, Spence, Matthew A, Vongsouthi, Vanessa, Jackson, Colin J

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Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering von Lee, Brendon M, Harold, Liam K, Almeida, Deepak V, Afriat-Jurnou, Livnat, Aung, Htin Lin, Forde, Brian M, Hards, Kiel, Pidot, Sacha J, Ahmed, F Hafna, Mohamed, A Elaaf, Taylor, Matthew C, West, Nicholas P, Stinear, Timothy P, Greening, Chris, Beatson, Scott A, Nuermberger, Eric L, Cook, Gregory M, Jackson, Colin J

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A revised biosynthetic pathway for the cofactor F420 in prokaryotes von Bashiri, Ghader, Antoney, James, Jirgis, Ehab N. M., Shah, Mihir V., Ney, Blair, Copp, Janine, Stuteley, Stephanie M., Sreebhavan, Sreevalsan, Palmer, Brian, Middleditch, Martin, Tokuriki, Nobuhiko, Greening, Chris, Scott, Colin, Baker, Edward N., Jackson, Colin J.

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Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics von Greule, Anja, Izoré, Thierry, Iftime, Dumitrita, Tailhades, Julien, Schoppet, Melanie, Zhao, Yongwei, Peschke, Madeleine, Ahmed, Iftekhar, Kulik, Andreas, Adamek, Martina, Goode, Robert J. A., Schittenhelm, Ralf B., Kaczmarski, Joe A., Jackson, Colin J., Ziemert, Nadine, Krenske, Elizabeth H., De Voss, James J., Stegmann, Evi, Cryle, Max J.

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Structure and function of an insect α-carboxylesterase (αEsterase7) associated with insecticide resistance von Jackson, Colin J., Liu, Jian-Wei, Carr, Paul D., Younus, Faisal, Coppin, Chris, Meirelles, Tamara, Lethier, Mathilde, Pandey, Gunjan, Ollis, David L., Russell, Robyn J., Weik, Martin, Oakeshott, John G.

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