An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma von Sahin, Ugur, Oehm, Petra, Derhovanessian, Evelyna, Jabulowsky, Robert A., Vormehr, Mathias, Gold, Maike, Maurus, Daniel, Schwarck-Kokarakis, Doreen, Kuhn, Andreas N., Omokoko, Tana, Kranz, Lena M., Diken, Mustafa, Kreiter, Sebastian, Haas, Heinrich, Attig, Sebastian, Rae, Richard, Cuk, Katarina, Kemmer-Brück, Alexandra, Breitkreuz, Andrea, Tolliver, Claudia, Caspar, Janina, Quinkhardt, Juliane, Hebich, Lisa, Stein, Malte, Hohberger, Alexander, Vogler, Isabel, Liebig, Inga, Renken, Stephanie, Sikorski, Julian, Leierer, Melanie, Müller, Verena, Mitzel-Rink, Heidrun, Miederer, Matthias, Huber, Christoph, Grabbe, Stephan, Utikal, Jochen, Pinter, Andreas, Kaufmann, Roland, Hassel, Jessica C., Loquai, Carmen, Türeci, Özlem

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Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy von Kranz, Lena M., Diken, Mustafa, Haas, Heinrich, Kreiter, Sebastian, Loquai, Carmen, Reuter, Kerstin C., Meng, Martin, Fritz, Daniel, Vascotto, Fulvia, Hefesha, Hossam, Grunwitz, Christian, Vormehr, Mathias, Hüsemann, Yves, Selmi, Abderraouf, Kuhn, Andreas N., Buck, Janina, Derhovanessian, Evelyna, Rae, Richard, Attig, Sebastian, Diekmann, Jan, Jabulowsky, Robert A., Heesch, Sandra, Hassel, Jessica, Langguth, Peter, Grabbe, Stephan, Huber, Christoph, Türeci, Özlem, Sahin, Ugur

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Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity von Horn, Axel V, Klawitter, Sabine, Held, Ulrike, Berger, André, Vasudevan, Ananda Ayyappan Jaguva, Bock, Anja, Hofmann, Henning, Hanschmann, Kay-Martin O, Trösemeier, Jan-Hendrik, Flory, Egbert, Jabulowsky, Robert A, Han, Jeffrey S, Löwer, Johannes, Löwer, Roswitha, Münk, Carsten, Schumann, Gerald G

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Antigen-specific oncolytic MV-based tumor vaccines through presentation of selected tumor-associated antigens on infected cells or virus-like particles von Hutzler, Stefan, Erbar, Stephanie, Jabulowsky, Robert A., Hanauer, Jan R. H., Schnotz, Jürgen H., Beissert, Tim, Bodmer, Bianca S., Eberle, Regina, Boller, Klaus, Klamp, Thorsten, Sahin, Ugur, Mühlebach, Michael D.

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Maltose-binding protein enhances secretion of recombinant human granzyme B accompanied by in vivo processing of a precursor MBP fusion protein von Dälken, Benjamin, Jabulowsky, Robert A, Oberoi, Pranav, Benhar, Itai, Wels, Winfried S

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EGFR-targeted granzyme B expressed in NK cells enhances natural cytotoxicity and mediates specific killing of tumor cells von Oberoi, Pranav, Jabulowsky, Robert A, Bähr-Mahmud, Hayat, Wels, Winfried S

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Cancer immunotherapy achieves breakthrough status: 12th annual meeting of the association for cancer immunotherapy (CIMT), Mainz, Germany, May 6–8, 2014 von Kloke, Björn-Philipp, Mahr, Andrea, Jabulowsky, Robert A., Kutscher, Sarah, Rae, Richard, Britten, Cedrik M.

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Surface Charge-Modification Prevents Sequestration and Enhances Tumor-Cell Specificity of a Recombinant Granzyme B–TGFα Fusion Protein von Jabulowsky, Robert A, Oberoi, Pranav, Bähr-Mahmud, Hayat, Dälken, Benjamin, Wels, Winfried S

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Selective Induction of Cancer Cell Death by Targeted Granzyme B von Oberoi, Pranav, Jabulowsky, Robert, Wels, Winfried

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A shared tumor-antigen RNA-lipoplex vaccine with/without anti-PD1 in patients with checkpoint-inhibition experienced melanoma von Loquai, Carmen, Hassel, Jessica Cecile, Oehm, Petra, Derhovanessian, Evelyna, Jabulowsky, Robert Alexander, Gold, Maike, Schwarck-Kokarakis, Doreen, Attig, Sebastian, Cuk, Katarina, Vogler, Isabel, Sikorski, Julian, Leierer, Melanie, Mitzel-Rink, Heidrun, Miederer, Matthias, Grabbe, Stephan, Utikal, Jochen, Pinter, Andreas, Kaufmann, Roland, Sahin, Ugur, Tureci, Oezlem

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Abstract CT156: A first-in-human phase I/II clinical trial assessing novel mRNA-lipoplex nanoparticles encoding shared tumor antigens for immunotherapy of malignant melanoma von Jabulowsky, Robert A., Loquai, Carmen, Mitzel-Rink, Heidrun, Utikal, Jochen, Gebhardt, Christoffer, Hassel, Jessica C., Kaufmann, Roland, Pinter, Andreas, Derhovanessian, Evelyna, Anft, Christine, Attig, Sebastian, Deubel, Alexandra, Diken, Mustafa, Gold, Maike, Guertler, Claudia, Haas, Heinrich, Heesen, Ludwig, Kemmer-Brück, Alexandra, Kranz, Lena M., Kuehlcke, Klaus, Kuhn, Andreas, Langguth, Peter, Luxemburger, Ulrich, Maurus, Daniel, Meng, Martin, Müller, Felicitas, Rae, Richard, Sari, Fatih, Schreeb, Katharina, Schwarck-Kokarakis, Doreen, Stein, Malte, Jäger, Dirk, Grabbe, Stephan, Kreiter, Sebastian, Huber, Christoph, Türeci, Özlem, Sahin, Ugur

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Abstract CT034: A first-in-human phase I/II clinical trial assessing novel mRNA-lipoplex nanoparticles for potent melanoma immunotherapy von Jabulowsky, Robert A., Loquai, Carmen, Utikal, Jochen, Hassel, Jessica, Kaufmann, Roland, Derhovanessian, Evelyna, Diken, Mustafa, Kranz, Lena M., Haas, Heinrich, Attig, Sebastian, Anft, Christine, Buck, Janina, Diekmann, Jan, Fritz, Daniel, Hartmann, Kerstin, Kemmer-Brueck, Alexandra, Kuehlcke, Klaus, Kuhn, Andreas N., Langguth, Peter, Luxemburger, Ulrich, Meng, Martin, Rae, Richard, Sari, Fatih, Schwarck-Kokarakis, Doreen, Stein, Malte, Grabbe, Stephan, Kreiter, Sebastian, Tuereci, Oezlem, Huber, Christoph, Sahin, Ugur

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Surface Charge-Modification Prevents Sequestration and Enhances Tumor-Cell Specificity of a Recombinant Granzyme B-TGFá Fusion Protein von Jabulowsky, Robert A, Oberoi, Pranav, Bähr-Mahmud, Hayat, Dälken, Benjamin, Wels, Winfried S

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Abstract CT032: A first-in-human phase III clinical trial assessing novel mRNA-lipoplex nanoparticles for potent cancer immunotherapy in patients with malignant melanoma von Jabulowsky, Robert A, Loquai, Carmen, Diken, Mustafa, Kranz, Lena M, Haas, Heinrich, Attig, Sebastian, Bidmon, Nicole, Buck, Janina, Derhovanessian, Evelyna, Diekmann, Jan, Fritz, Daniel, Jahndel, Veronika, Kemmer-Brueck, Alexandra, Kuehlcke, Klaus, Kuhn, Andreas N, Langguth, Peter, Luxemburger, Ulrich, Meng, Martin, Mueller, Felicitas, Rae, Richard, Sari, Fatih, Schwarck-Kokarakis, Doreen, Seck, Christine, Spie, Kristina, Witt, Meike, Hassel, Jessica C, Utikal, Jochen, Kaufmann, Roland, Kreiter, Sebastian, Huber, Christoph, Tuereci, Oezlem, Sahin, Ugur

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Abstract CT032: A first-in-human phase I/II clinical trial assessing novel mRNA-lipoplex nanoparticles for potent cancer immunotherapy in patients with malignant melanoma von Jabulowsky, Robert A., Loquai, Carmen, Diken, Mustafa, Kranz, Lena M., Haas, Heinrich, Attig, Sebastian, Bidmon, Nicole, Buck, Janina, Derhovanessian, Evelyna, Diekmann, Jan, Fritz, Daniel, Jahndel, Veronika, Kemmer-Brueck, Alexandra, Kuehlcke, Klaus, Kuhn, Andreas N., Langguth, Peter, Luxemburger, Ulrich, Meng, Martin, Mueller, Felicitas, Rae, Richard, Sari, Fatih, Schwarck-Kokarakis, Doreen, Seck, Christine, Spieß, Kristina, Witt, Meike, Hassel, Jessica C., Utikal, Jochen, Kaufmann, Roland, Kreiter, Sebastian, Huber, Christoph, Tuereci, Oezlem, Sahin, Ugur

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Abstract B040: Oncolytic measles virus for tumor vaccination von Hutzler, Stefan, Erbar, Stephanie, Jabulowsky, Robert A., Beissert, Tim, Hanauer, Jan, Tuereci, Oezlem, Mitnacht-Kraus, Rita, Kreiter, Sebastian, Diken, Mustafa, Britten, Cedrik M., Sahin, Ugur, Muehlebach, Michael D.

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Abstract A004: Systemic RNA vaccines: Connecting effective cancer immunotherapy with antiviral defense mechanisms von Kranz, Lena M., Diken, Mustafa, Haas, Heinrich, Kreiter, Sebastian, Loquai, Carmen, Reuter, Kerstin C., Meng, Martin, Fritz, Daniel, Vascotto, Fulvia, Hefesha, Hossam, Grunwitz, Christian, Vormehr, Mathias, Hüsemann, Yves, Selmi, Abderraouf, Kuhn, Andreas N., Buck, Janina, Derhovanessian, Evelyna, Rae, Richard, Attig, Sebastian, Diekmann, Jan, Jabulowsky, Robert A., Heesch, Sandra, Hassel, Jessica, Langguth, Peter, Grabbe, Stephan, Huber, Christoph, Türeci, Özlem, Sahin, Ugur

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Abstract B041: A novel nanoparticular formulated tetravalent RNA cancer vaccine for treatment of patients with malignant melanoma von Jabulowsky, Robert A., Loquai, Carmen, Diken, Mustafa, Kranz, Lena M., Haas, Heinrich, Attig, Sebastian, Britten, Cedrik M., Buck, Janina, Derhovanessian, Evelyna, Diekmann, Jan, Esparza, Isaac, Fritz, Daniel, Huesemann, Yves, Jahndel, Veronika, Kuehlcke, Klaus, Kuhn, Andreas N., Langguth, Peter, Luxemburger, Ulrich, Meng, Martin, Mueller, Felicitas, Reuter, Kerstin C., Schwarck, Doreen, Spiess, Kristina, Witt, Meike, Hassel, Jessica C., Utikal, Jochen, Kaufmann, Roland, Schrott, Marc, Kreiter, Sebastian, Tuereci, Oezlem, Huber, Christoph, Sahin, Ugur

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EGFR-Targeted Granzyme B Expressed in NK Cells Enhances Natural Cytotoxicity and Mediates Specific Killing of Tumor Cells. e61267 von Oberoi, Pranav, Jabulowsky, Robert A, Baehr-Mahmud, Hayat, Wels, Winfried S

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COMPOSITIONS AND METHODS FOR TREATMENT OF MELANOMA von SCHWARCK-KOKARAKIS, Doreen, TÜRECI, Özlem, SAHIN, Ugur, JABULOWSKY, Robert A

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