mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3 von Dodd, K M, Yang, J, Shen, M H, Sampson, J R, Tee, A R

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Beckwith-Wiedemann syndrome and assisted reproduction technology (ART) von Maher, E R, Brueton, L A, Bowdin, S C, Luharia, A, Cooper, W, Cole, T R, Macdonald, F, Sampson, J R, Barratt, C L, Reik, W, Hawkins, M M

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Renal tumours in a [Tsc2.sup.+/-] mouse model do not show feedback inhibition of Akt and are effectively prevented by rapamycin von Yang, J, Kalogerou, M, Samsel, P.A, Zhang, Y, Griffiths, D.F.R, Gallacher, J, Sampson, J.R, Shen, M.H

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Genotype and psychological phenotype in tuberous sclerosis von Lewis, J C, Thomas, H V, Murphy, K C, Sampson, J R

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Evaluation of Clinical Manifestations in Patients with Severe Lymphedema with and without CCBE1 Mutations von Alders, M., Mendola, A., Adès, L., Al Gazali, L., Bellini, C., Dallapiccola, B., Edery, P., Frank, U., Hornshuh, F., Huisman, S.A., Jagadeesh, S., Kayserili, H., Keng, W.T., Lev, D., Prada, C.E., Sampson, J.R., Schmidtke, J., Shashi, V., van Bever, Y., Van der Aa, N., Verhagen, J.M., Verheij, J.B., Vikkula, M., Hennekam, R.C.

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Biochemical and physical characterization of an unmodified yeast phenylalanine transfer RNA transcribed in vitro von Sampson, J.R, Uhlenbeck, O.C

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Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospec... von Dominguez-Valentin, M., Haupt, S., Seppälä, T.T., Sampson, J.R., Sunde, L., Bernstein, I., Jenkins, M.A., Engel, C., Aretz, S., Nielsen, M., Capella, G., Balaguer, F., Evans, D.G., Burn, J., Holinski-Feder, E., Bertario, L., Bonanni, B., Lindblom, A., Levi, Z., Macrae, F., Winship, I., Plazzer, J.P., Sijmons, R., Laghi, L., Valle, A., Heinimann, K., Debniak, T., Fruscio, R., Lopez-Koestner, F., Alvarez-Valenzuela, K., Katz, L.H., Vainer, E., Carraro, D.M., Monahan, K., Half, E., Stakelum, A., Kennelly, R., Gluck, N., Sheth, H., Greenblatt, M., Rossi, B.M., Cavestro, G.M., Lino-Silva, L.S., Horisberger, K., Tibiletti, M.G., Nascimento, I., Rossi, N.T., Silva, L.A. da, Zarand, A., Ruiz-Banobre, J., Heuveline, V., Mecklin, J.P., Pylvänäinen, K., Renkonen-Sinisalo, L., Lepistö, A., Peltomäki, P., Therkildsen, C., Madsen, M.G., Burgdorf, S.K., Hopper, J.L., Win, A.K., Haile, R.W., Lindor, N., Gallinge, S., Marchand, L. le, Buchanan, D.D., Thibodeau, S.N., Doeberitz, M.V., Loeffler, M., Rahner, N., Schröck, E., Schmiegel, W., Perne, C., Redler, S., Büttner, R., Pineda, M., Duenas, N., Vidal, J.B., Sánchez, A., Hovig, E., Nakken, S., Green, K., Lalloo, F., Hill, J., Mints, M., Goldberg, Y., Tjandra, D., Broeke, S.W. ten, Kariv, R., Rosner, G., Advani, S.H., Shah, P., Shah, M., Neffa, F., Esperon, P., Pavicic, W., Torrezan, G.T., Bassaneze, T., Martin, C.A., Moller, P.

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Structure of an unmodified tRNA molecule von Hall, Kathleen B, Sampson, Jeffrey R, Uhlenbeck, Olke C, Redfield, Alfred G

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ADAPTIVE SEARCH USING A REPRODUCTIVE META-PLAN von MERCER, R.E, SAMPSON, J.R

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The "unnatural" history of colorectal cancer in Lynch syndrome: lessons from colonoscopy surveillance von Ahadova, A., Seppala, T.T., Engel, C., Gallon, R., Burn, J., Holinski-Feder, E., Steinke-Lange, V., Moslein, G., Nielsen, M., Broeke, S.W. ten, Laghi, L., Dominguez-Valentin, M., Capella, G., Macrae, F., Scott, R., Huneburg, R., Nattermann, J., Hoffmeister, M., Brenner, H., Blaker, H., Doeberitz, M.V., Sampson, J.R., Vasen, H., Mecklin, J.P., Moller, P., Kloor, M.

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Tuberous sclerosis complex (TSC) : expert recommendations for provision of coordinated care von Annear, N.M.P, Appleton, R.E, Bassi, Z, Bhatt, R, Bolton, P.F, Crawford, P, Crowe, A, Tossi, M, Elmslie, F, Finlay, E, Gale, D.P, Henderson, A, Jones, E.A, Johnson, S.R, Joss, S, Kerecuk, L, Lipkin, G, Morrison, P.J, O'Callaghan, F.J, Cadwgan, J, Ong, A.C.M, Sampson, J.R, Shepherd, C, Kingswood, J.C

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No difference in penetrance between truncating and missense/aberrant splicing pathogenic variants in MLH1 and MSH2: a prospective Lynch syndrome database study von Dominguez-Valentin, M., Plazzer, J.P., Sampson, J.R., Engel, C., Aretz, S., Jenkins, M.A., Sunde, L., Bernstein, I., Capella, G., Balaguer, F., Macrae, F., Winship, I.M., Thomas, H., Evans, D.G., Burn, J., Greenblatt, M., Cappel, W.H.D.T.N., Sijmons, R.H., Nielsen, M., Bertario, L., Bonanni, B., Tibiletti, M.G., Cavestro, G.M., Lindblom, A., Valle, A. della, Lopez-Kostner, F., Alvarez, K., Gluck, N., Katz, L., Heinimann, K., Vaccaro, C.A., Nakken, S., Hovig, E., Green, K., Lalloo, F., Hill, J., Vasen, H.F.A., Perne, C., Buttner, R., Gorgens, H., Holinski-Feder, E., Morak, M., Holzapfel, S., Huneburg, R., Doeberitz, M.V., Loeffler, M., Rahner, N., Weitz, J., Steinke-Lange, V., Schmiegel, W., Vangala, D., Crosbie, E.J., Pineda, M., Navarro, M., Brunet, J., Moreira, L., Sanchez, A., Serra-Burriel, M., Mints, M., Kariv, R., Rosner, G., Pinero, T.A., Pavicic, W.H., Kalfayan, P., Broeke, S.W. ten, Mecklin, J.P., Pylvanainen, K., Renkonen-Sinisalo, L., Lepisto, A., Peltomaki, P., Hopper, J.L., Win, A.K., Buchanan, D.D., Lindor, N.M., Gallinger, S., Marchand, L. le, Newcomb, P.A., Figueiredo, J.C., Thibodeau, S.N., Therkildsen, C., Hansen, T.V.O., Lindberg, L., Rodland, E.A., Neffa, F., Esperon, P., Tjandra, D., Moslein, G., Seppala, T.T., Moller, P.

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Risk-reducing gynecological surgery in Lynch syndrome: results of an international survey from the prospective Lynch syndrome database von Dominguez-Valentin, M., Seppala, T.T., Engel, C., Aretz, S., Macrae, F., Winship, I., Capella, G., Thomas, H., Hovig, E., Nielsen, M., Sijmons, R.H., Bertario, L., Bonanni, B., Tibiletti, M.G., Cavestro, G.M., Mints, M., Gluck, N., Katz, L., Heinimann, K., Vaccaro, C.A., Green, K., Lalloo, F., Hill, J., Schmiegel, W., Vangala, D., Perne, C., Strauss, H.G., Tecklenburg, J., Holinski-Feder, E., Steinke-Lange, V., Mecklin, J.P., Plazzer, J.P., Pineda, M., Navarro, M., Vidal, J.B., Kariv, R., Rosner, G., Pinero, T.A., Gonzalez, M.L., Kalfayan, P., Sampson, J.R., Ryan, N.A.J., Evans, D.G., Moller, P., Crosbie, E.J.

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Risk-reducing gynecological surgery in Lynch syndrome: results of an international survey from the prospective Lynch syndrome database von Dominguez-Valentin, M., Seppälä, T.T., Engel, C., Aretz, S., Macrae, F., Winship, I., Capella, G., Thomas, H., Hovig, E., Nielsen, M., Sijmons, R.H., Bertario, L., Bonanni, B., Tibiletti, M.G., Cavestro, G.M., Mints, M., Gluck, N., Katz, L., Heinimann, K., Vaccaro, C.A., Green, K., Lalloo, F., Hill, J., Schmiegel, W., Vangala, D., Perne, C., Strauss, H.G., Tecklenburg, J., Holinski-Feder, E., Steinke-Lange, V., Mecklin, J.P., Plazzer, J.P., Pineda, M., Navarro, M., Vidal, J.B., Kariv, R., Rosner, G., Piñero, T.A., Gonzalez, M.L., Kalfayan, P., Sampson, J.R., Ryan, N.A.J., Evans, D.G., Moller, P., Crosbie, E.J.

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Uptake of hysterectomy and bilateral salpingooophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report von Seppala, T.T., Dominguez-Valentin, M., Crosbie, E.J., Engel, C., Aretz, S., Macrae, F., Winship, I., Capella, G., Thomas, H., Hovig, E., Nielsen, M., Sijmons, R.H., Bertario, L., Bonanni, B., Tibiletti, M.G., Cavestro, G.M., Mints, M., Gluck, N., Katz, L., Heinimann, K., Vaccaro, C.A., Green, K., Lalloo, F., Hill, J., Schmiegel, W., Vangala, D., Perne, C., Strauss, H.G., Tecklenburg, J., Holinski-Feder, E., Steinke-Lange, V., Mecklin, J.P., Plazzer, J.P., Pineda, M., Navarro, M., Vida, J.B., Kariv, R., Rosner, G., Pinero, T.A., Pavicic, W., Kalfayan, P., Broeke, S.W. ten, Jenkins, M.A., Sunde, L., Bernstein, I., Burn, J., Greenblatt, M., Cappel, W.H.D.T.N., Valle, A. della, Lopez-Koestner, F., Alvarez, K., Buttner, R., Gorgens, H., Morak, M., Holzapfel, S., Huneburg, R., Doeberitz, M.V., Loeffler, M., Redler, S., Weitz, J., Pylvanainen, K., Renkonen-Sinisalo, L., Lepisto, A., Hopper, J.L., Win, A.K., Lindor, N.M., Gallinger, S., Marchand, L.L., Newcomb, P.A., Figueiredo, J.C., Thibodeau, S.N., Therkildsen, C., Wadt, K.A.W., Mourits, M.J.E., Ketabi, Z., Denton, O.G., Rodland, E.A., Vasen, H., Neffa, F., Esperon, P., Tjandra, D., Moslein, G., Rokkones, E., Sampson, J.R., Evans, D.G., Moller, P.

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Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report von Dominguez-Valentin, M., Crosbie, E.J., Engel, C., Aretz, S., Macrae, F., Winship, I., Capella, G., Thomas, H., Nakken, S., Hovig, E., Nielsen, M., Sijmons, R.H., Bertario, L., Bonanni, B., Tibiletti, M.G., Cavestro, G.M., Mints, M., Gluck, N., Katz, L., Heinimann, K., Vaccaro, C.A., Green, K., Lalloo, F., Hill, J., Schmiegel, W., Vangala, D., Perne, C., Strauss, H.G., Tecklenburg, J., Holinski-Feder, E., Steinke-Lange, V., Mecklin, J.P., Plazzer, J.P., Pineda, M., Navarro, M., Vidal, J.B., Kariv, R., Rosner, G., Pinero, T.A., Gonzalez, M.L., Kalfayan, P., Ryan, N., Broeke, S.W. ten, Jenkins, M.A., Sunde, L., Bernstein, I., Burn, J., Greenblatt, M., Cappel, W.H.D.T.N., Valle, A. della, Lopez-Koestner, F., Alvarez, K., Buttner, R., Gorgens, H., Morak, M., Holzapfel, S., Huneburg, R., Doeberitz, M.V., Loeffler, M., Rahner, N., Weitz, J., Pylvanainen, K., Renkonen-Sinisalo, L., Lepisto, A., Auranen, A., Hopper, J.L., Win, A.K., Haile, R.W., Lindor, N.M., Gallinger, S., Marchand, L. le, Newcomb, P.A., Figueiredo, J.C., Thibodeau, S.N., Therkildsen, C., Okkels, H., Ketabi, Z., Denton, O.G., Rodland, E.A., Vasen, H., Neffa, F., Esperon, P., Tjandra, D., Moslein, G., Sampson, J.R., Evans, D.G., Seppala, T.T., Moller, P.

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Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report von Dominguez-Valentin, M., Seppälä, T.T., Sampson, J.R., Macrae, F., Winship, I., Evans, D.G., Scott, R.J., Burn, J., Möslein, G., Bernstein, I., Pylvänäinen, K., Renkonen-Sinisalo, L., Lepistö, A., Lindblom, A., Plazzer, J.P., Tjandra, D., Thomas, H., Green, K., Lalloo, F., Crosbie, E.J., Hill, J., Capella, G., Pineda, M., Navarro, M., Vidal, J.B., Ronlund, K., Nielsen, R.T., Yilmaz, M., Elvang, L.L., Katz, L., Nielsen, M., Broeke, S.W. ten, Nakken, S., Hovig, E., Sunde, L., Kloor, M., Doeberitz, M.V., Ahadova, A., Lindor, N., Steinke-Lange, V., Holinski-Feder, E., Mecklin, J.P., Moller, P.

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Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database von Moller, P., Seppala, T.T., Bernstein, I., Holinski-Feder, E., Sala, P., Evans, D.G., Lindblom, A., Macrae, F., Blanco, I., Sijmons, R.H., Jeffries, J., Vasen, H.F.A., Burn, J., Nakken, S., Hovig, E., Rodland, E.A., Tharmaratnam, K., Cappel, W.H.D.T.N., Hill, J., Wijnen, J.T., Jenkins, M.A., Green, K., Lalloo, F., Sunde, L., Mints, M., Bertario, L., Pineda, M., Navarro, M., Morak, M., Renkonen-Sinisalo, L., Valentin, M.D., Frayling, I.M., Plazzer, J.P., Pylvanainen, K., Genuardi, M., Mecklin, J.P., Moeslein, G., Sampson, J.R., Capella, G.

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Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database von Dominguez-Valentin, M., Sampson, J.R., Seppala, T.T., Broeke, S.W. ten, Plazzer, J.P., Nakken, S., Engel, C., Aretz, S., Jenkins, M.A., Sunde, L., Bernstein, I., Capella, G., Balaguer, F., Thomas, H., Evans, D.G., Burn, J., Greenblatt, M., Hovig, E., Cappel, W.H.D.T.N.C., Sijmons, R.H., Bertario, L., Tibiletti, M.G., Cavestro, G.M., Lindblom, A., Valle, A. della, Lopez-Kostner, F., Gluck, N., Katz, L.H., Heinimann, K., Vaccaro, C.A., Buttner, R., Gorgens, H., Holinski-Feder, E., Morak, M., Holzapfel, S., Huneburg, R., Doeberitz, M.V., Loeffler, M., Rahner, N., Schackert, H.K., Steinke-Lange, V., Schmiegel, W., Vangala, D., Pylvanainen, K., Renkonen-Sinisalo, L., Hopper, J.L., Win, A.K., Haile, R.W., Lindor, N.M., Gallinger, S., Marchand, L. le, Newcomb, P.A., Figueiredo, J.C., Thibodeau, S.N., Wadt, K., Therkildsen, C., Okkels, H., Ketabi, Z., Moreira, L., Sanchez, A., Serra-Burriel, M., Pineda, M., Navarro, M., Blanco, I., Green, K., Lalloo, F., Crosbie, E.J., Hill, J., Denton, O.G., Frayling, I.M., Rodland, E.A., Vasen, H., Mints, M., Neffa, F., Esperon, P., Alvarez, K., Kariv, R., Rosner, G., Pinero, T.A., Gonzalez, M.L., Kalfayan, P., Tjandra, D., Winship, I.M., Macrae, F., Moslein, G., Mecklin, J.P., Nielsen, M., Moller, P.

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ultraviolet light-induced crosslink in yeast tRNA(phe) von Behlen, L.S, Sampson, J.R, Uhlenbeck, O.C

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