Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses von Shaw, Andrew E, Hughes, Joseph, Gu, Quan, Behdenna, Abdelkader, Singer, Joshua B, Dennis, Tristan, Orton, Richard J, Varela, Mariana, Gifford, Robert J, Wilson, Sam J, Palmarini, Massimo

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In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2 von Szemiel, Agnieszka M, Merits, Andres, Orton, Richard J, MacLean, Oscar A, Pinto, Rute Maria, Wickenhagen, Arthur, Lieber, Gauthier, Turnbull, Matthew L, Wang, Sainan, Furnon, Wilhelm, Suarez, Nicolas M, Mair, Daniel, da Silva Filipe, Ana, Willett, Brian J, Wilson, Sam J, Patel, Arvind H, Thomson, Emma C, Palmarini, Massimo, Kohl, Alain, Stewart, Meredith E

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TRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction von Galão, Rui Pedro, Wilson, Harry, Schierhorn, Kristina L, Debeljak, Franka, Bodmer, Bianca S, Goldhill, Daniel, Hoenen, Thomas, Wilson, Sam J, Swanson, Chad M, Neil, Stuart J D

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Identification of Interferon-Stimulated Genes with Antiretroviral Activity von Kane, Melissa, Zang, Trinity M., Rihn, Suzannah J., Zhang, Fengwen, Kueck, Tonya, Alim, Mudathir, Schoggins, John, Rice, Charles M., Wilson, Sam J., Bieniasz, Paul D.

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A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research von Rihn, Suzannah J, Merits, Andres, Bakshi, Siddharth, Turnbull, Matthew L, Wickenhagen, Arthur, Alexander, Akira J T, Baillie, Carla, Brennan, Benjamin, Brown, Fiona, Brunker, Kirstyn, Bryden, Steven R, Burness, Kerry A, Carmichael, Stephen, Cole, Sarah J, Cowton, Vanessa M, Davies, Paul, Davis, Chris, De Lorenzo, Giuditta, Donald, Claire L, Dorward, Mark, Dunlop, James I, Elliott, Matthew, Fares, Mazigh, da Silva Filipe, Ana, Freitas, Joseph R, Furnon, Wilhelm, Gestuveo, Rommel J, Geyer, Anna, Giesel, Daniel, Goldfarb, Daniel M, Goodman, Nicola, Gunson, Rory, Hastie, C James, Herder, Vanessa, Hughes, Joseph, Johnson, Clare, Johnson, Natasha, Kohl, Alain, Kerr, Karen, Leech, Hannah, Lello, Laura Sandra, Li, Kathy, Lieber, Gauthier, Liu, Xiang, Lingala, Rajendra, Loney, Colin, Mair, Daniel, McElwee, Marion J, McFarlane, Steven, Nichols, Jenna, Nomikou, Kyriaki, Orr, Anne, Orton, Richard J, Palmarini, Massimo, Parr, Yasmin A, Pinto, Rute Maria, Raggett, Samantha, Reid, Elaine, Robertson, David L, Royle, Jamie, Cameron-Ruiz, Natalia, Shepherd, James G, Smollett, Katherine, Stewart, Douglas G, Stewart, Meredith, Sugrue, Elena, Szemiel, Agnieszka M, Taggart, Aislynn, Thomson, Emma C, Tong, Lily, Torrie, Leah S, Toth, Rachel, Varjak, Margus, Wang, Sainan, Wilkinson, Stuart G, Wyatt, Paul G, Zusinaite, Eva, Alessi, Dario R, Patel, Arvind H, Zaid, Ali, Wilson, Sam J, Mahalingam, Suresh

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MX2 is an interferon-induced inhibitor of HIV-1 infection von Kane, Melissa, Yadav, Shalini S., Bitzegeio, Julia, Kutluay, Sebla B., Zang, Trinity, Wilson, Sam J., Schoggins, John W., Rice, Charles M., Yamashita, Masahiro, Hatziioannou, Theodora, Bieniasz, Paul D.

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A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation von Dittmann, Meike, Hoffmann, Hans-Heinrich, Scull, Margaret A., Gilmore, Rachel H., Bell, Kierstin L., Ciancanelli, Michael, Wilson, Sam J., Crotta, Stefania, Yu, Yingpu, Flatley, Brenna, Xiao, Jing W., Casanova, Jean-Laurent, Wack, Andreas, Bieniasz, Paul D., Rice, Charles M.

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Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene von Lin, Yao-Tang, Chiweshe, Stephen, McCormick, Dominique, Raper, Anna, Wickenhagen, Arthur, DeFillipis, Victor, Gaunt, Eleanor, Simmonds, Peter, Wilson, Sam J, Grey, Finn

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Extreme genetic fragility of the HIV-1 capsid von Rihn, Suzannah J, Wilson, Sam J, Loman, Nick J, Alim, Mudathir, Bakker, Saskia E, Bhella, David, Gifford, Robert J, Rixon, Frazer J, Bieniasz, Paul D

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The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin von Pardieu, Claire, Vigan, Raphaël, Wilson, Sam J, Calvi, Alessandra, Zang, Trinity, Bieniasz, Paul, Kellam, Paul, Towers, Greg J, Neil, Stuart J D

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Host and viral determinants of Mx2 antiretroviral activity von Busnadiego, Idoia, Kane, Melissa, Rihn, Suzannah J, Preugschas, Hannah F, Hughes, Joseph, Blanco-Melo, Daniel, Strouvelle, Victoria P, Zang, Trinity M, Willett, Brian J, Boutell, Chris, Bieniasz, Paul D, Wilson, Sam J

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Resurrection of 2'-5'-oligoadenylate synthetase 1 (OAS1) from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication von Lytras, Spyros, Wickenhagen, Arthur, Sugrue, Elena, Stewart, Douglas G, Swingler, Simon, Sims, Anna, Jackson Ireland, Hollie, Davies, Emma L, Ludlam, Eliza M, Li, Zhuonan, Hughes, Joseph, Wilson, Sam J

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SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies von Fielding, Ceri Alan, Sabberwal, Pragati, Williamson, James C, Greenwood, Edward J D, Crozier, Thomas W M, Zelek, Wioleta, Seow, Jeffrey, Graham, Carl, Huettner, Isabella, Edgeworth, Jonathan D, Price, David A, Morgan, Paul B, Ladell, Kristin, Eberl, Matthias, Humphreys, Ian R, Merrick, Blair, Doores, Katie, Wilson, Sam J, Lehner, Paul J, Wang, Eddie C Y, Stanton, Richard J

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Targeted degradation of zDHHC-PATs decreases substrate S-palmitoylation von Bai, Mingjie, Gallen, Emily, Memarzadeh, Sarah, Howie, Jacqueline, Gao, Xing, Kuo, Chien-Wen S, Brown, Elaine, Swingler, Simon, Wilson, Sam J, Shattock, Michael J, France, David J, Fuller, William

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Nef proteins from simian immunodeficiency viruses are tetherin antagonists von Zhang, Fengwen, Wilson, Sam J, Landford, Wilmina C, Virgen, Beatriz, Gregory, Devon, Johnson, Marc C, Munch, Jan, Kirchhoff, Frank, Bieniasz, Paul D, Hatziioannou, Theodora

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A specific domain within the 3′ untranslated region of Usutu virus confers resistance to the exonuclease ISG20 von Zoladek, Jim, El Kazzi, Priscila, Caval, Vincent, Vivet-Boudou, Valérie, Cannac, Marion, Davies, Emma L., Rossi, Soléna, Bribes, Inès, Rouilly, Lucile, Simonin, Yannick, Jouvenet, Nolwenn, Decroly, Etienne, Paillart, Jean-Christophe, Wilson, Sam J., Nisole, Sébastien

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The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting von Shaw, Andrew E, Rihn, Suzannah J, Mollentze, Nardus, Wickenhagen, Arthur, Stewart, Douglas G, Orton, Richard J, Kuchi, Srikeerthana, Bakshi, Siddharth, Collados, Mila Rodriguez, Turnbull, Matthew L, Busby, Joseph, Gu, Quan, Smollett, Katherine, Bamford, Connor G G, Sugrue, Elena, Johnson, Paul C D, Da Silva, Ana Filipe, Castello, Alfredo, Streicker, Daniel G, Robertson, David L, Palmarini, Massimo, Wilson, Sam J

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The apparent interferon resistance of transmitted HIV-1 is possibly a consequence of enhanced replicative fitness von Sugrue, Elena, Wickenhagen, Arthur, Mollentze, Nardus, Aziz, Muhamad Afiq, Sreenu, Vattipally B, Truxa, Sven, Tong, Lily, da Silva Filipe, Ana, Robertson, David L, Hughes, Joseph, Rihn, Suzannah J, Wilson, Sam J

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Synthesis, Enantiomeric Resolution and Biological Evaluation of HIV Capsid Inhibition Activity for Racemic, (S)- and (R)-PF74 von Ruddell, Stuart, Sugrue, Elena, Memarzadeh, Sarah, Hellam, Lorna Mae, Wilson, Sam J., France, David J.

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The Timing and Magnitude of the Type I Interferon Response Are Correlated with Disease Tolerance in Arbovirus Infection von Hardy, Alexandra, Bakshi, Siddharth, Furnon, Wilhelm, MacLean, Oscar, Gu, Quan, Varjak, Margus, Varela, Mariana, Aziz, Muhamad Afiq, Shaw, Andrew E, Pinto, Rute Maria, Cameron Ruiz, Natalia, Mullan, Catrina, Taggart, Aislynn E, Da Silva Filipe, Ana, Randall, Richard E, Wilson, Sam J, Stewart, Meredith E, Palmarini, Massimo

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