AMPK: guardian of metabolism and mitochondrial homeostasis von Herzig, Sébastien, Shaw, Reuben J.

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AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance von Garcia, Daniel, Shaw, Reuben J.

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AMPK: restoring metabolic homeostasis over space and time von Trefts, Elijah, Shaw, Reuben J.

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Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates von Egan, Daniel F., Chun, Matthew G.H., Vamos, Mitchell, Zou, Haixia, Rong, Juan, Miller, Chad J., Lou, Hua Jane, Raveendra-Panickar, Dhanya, Yang, Chih-Cheng, Sheffler, Douglas J., Teriete, Peter, Asara, John M., Turk, Benjamin E., Cosford, Nicholas D.P., Shaw, Reuben J.

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Autophagic cell death restricts chromosomal instability during replicative crisis von Nassour, Joe, Radford, Robert, Correia, Adriana, Fusté, Javier Miralles, Schoell, Brigitte, Jauch, Anna, Shaw, Reuben J., Karlseder, Jan

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AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice von Li, Yu, Xu, Shanqin, Mihaylova, Maria M., Zheng, Bin, Hou, Xiuyun, Jiang, Bingbing, Park, Ogyi, Luo, Zhijun, Lefai, Etienne, Shyy, John Y.-J., Gao, Bin, Wierzbicki, Michel, Verbeuren, Tony J., Shaw, Reuben J., Cohen, Richard A., Zang, Mengwei

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LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin von Shackelford, David B., Abt, Evan, Gerken, Laurie, Vasquez, Debbie S., Seki, Atsuko, Leblanc, Mathias, Wei, Liu, Fishbein, Michael C., Czernin, Johannes, Mischel, Paul S., Shaw, Reuben J.

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AMP-activated protein kinase mediates mitochondrial fission in response to energy stress von Toyama, Erin Quan, Herzig, Sébastien, Courchet, Julien, Lewis, Tommy L., Losón, Oliver C., Hellberg, Kristina, Young, Nathan P., Chen, Hsiuchen, Polleux, Franck, Chan, David C., Shaw, Reuben J.

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Transcriptional Coregulators: Fine-Tuning Metabolism von Mouchiroud, Laurent, Eichner, Lillian J., Shaw, Reuben J., Auwerx, Johan

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Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex von Howell, Jessica J., Hellberg, Kristina, Turner, Marc, Talbott, George, Kolar, Matthew J., Ross, Debbie S., Hoxhaj, Gerta, Saghatelian, Alan, Shaw, Reuben J., Manning, Brendan D.

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mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc von Masui, Kenta, Tanaka, Kazuhiro, Akhavan, David, Babic, Ivan, Gini, Beatrice, Matsutani, Tomoo, Iwanami, Akio, Liu, Feng, Villa, Genaro R., Gu, Yuchao, Campos, Carl, Zhu, Shaojun, Yang, Huijun, Yong, William H., Cloughesy, Timothy F., Mellinghoff, Ingo K., Cavenee, Webster K., Shaw, Reuben J., Mischel, Paul S.

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Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity von Merkwirth, Carsten, Jovaisaite, Virginija, Durieux, Jenni, Matilainen, Olli, Jordan, Sabine D., Quiros, Pedro M., Steffen, Kristan K., Williams, Evan G., Mouchiroud, Laurent, Tronnes, Sarah U., Murillo, Virginia, Wolff, Suzanne C., Shaw, Reuben J., Auwerx, Johan, Dillin, Andrew

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Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis von Mihaylova, Maria M., Vasquez, Debbie S., Ravnskjaer, Kim, Denechaud, Pierre-Damien, Yu, Ruth T., Alvarez, Jacqueline G., Downes, Michael, Evans, Ronald M., Montminy, Marc, Shaw, Reuben J.

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Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models von Svensson, Robert U, Parker, Seth J, Eichner, Lillian J, Kolar, Matthew J, Wallace, Martina, Brun, Sonja N, Lombardo, Portia S, Van Nostrand, Jeanine L, Hutchins, Amanda, Vera, Lilliana, Gerken, Laurie, Greenwood, Jeremy, Bhat, Sathesh, Harriman, Geraldine, Westlin, William F, Harwood, H James, Saghatelian, Alan, Kapeller, Rosana, Metallo, Christian M, Shaw, Reuben J

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The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR von Egan, Dan, Kim, Joungmok, Shaw, Reuben J., Guan, Kun-Liang

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Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction von Schaffer, Bethany E., Levin, Rebecca S., Hertz, Nicholas T., Maures, Travis J., Schoof, Michael L., Hollstein, Pablo E., Benayoun, Bérénice A., Banko, Max R., Shaw, Reuben J., Shokat, Kevan M., Brunet, Anne

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Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD von Garcia, Daniel, Hellberg, Kristina, Chaix, Amandine, Wallace, Martina, Herzig, Sébastien, Badur, Mehmet G., Lin, Terry, Shokhirev, Maxim N., Pinto, Antonio F.M., Ross, Debbie S., Saghatelian, Alan, Panda, Satchidananda, Dow, Lukas E., Metallo, Christian M., Shaw, Reuben J.

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AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes von Young, Nathan P, Kamireddy, Anwesh, Van Nostrand, Jeanine L, Eichner, Lillian J, Shokhirev, Maxim Nikolaievich, Dayn, Yelena, Shaw, Reuben J

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Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy von Egan, Daniel F, Shackelford, David B, Mihaylova, Maria M, Gelino, Sara, Kohnz, Rebecca A, Mair, William, Vasquez, Debbie S, Joshi, Aashish, Gwinn, Dana M, Taylor, Rebecca, Asara, John M, Fitzpatrick, James, Dillin, Andrew, Viollet, Benoit, Kundu, Mondira, Hansen, Malene, Shaw, Reuben J

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AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint von Gwinn, Dana M., Shackelford, David B., Egan, Daniel F., Mihaylova, Maria M., Mery, Annabelle, Vasquez, Debbie S., Turk, Benjamin E., Shaw, Reuben J.

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