Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring MET Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors in Non... von Engstrom, Lars D, Aranda, Ruth, Lee, Matthew, Tovar, Elizabeth A, Essenburg, Curt J, Madaj, Zachary, Chiang, Harrah, Briere, David, Hallin, Jill, Lopez-Casas, Pedro P, Baños, Natalia, Menendez, Camino, Hidalgo, Manuel, Tassell, Vanessa, Chao, Richard, Chudova, Darya I, Lanman, Richard B, Olson, Peter, Bazhenova, Lyudmilla, Patel, Sandip Pravin, Graveel, Carrie, Nishino, Mizuki, Shapiro, Geoffrey I, Peled, Nir, Awad, Mark M, Jänne, Pasi A, Christensen, James G

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Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors von Peacock, Jacqueline D, Pridgeon, Matthew G, Tovar, Elizabeth A, Essenburg, Curt J, Bowman, Megan, Madaj, Zachary, Koeman, Julie, Boguslawski, Elissa A, Grit, Jamie, Dodd, Rebecca D, Khachaturov, Vadim, Cardona, Diana M, Chen, Mark, Kirsch, David G, Maina, Flavio, Dono, Rosanna, Winn, Mary E, Graveel, Carrie R, Steensma, Matthew R

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Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/p38 signaling von Grit, Jamie L, Johnson, Benjamin K, Dischinger, Patrick S, J Essenburg, Curt, Adams, Marie, Campbell, Stacy, Pollard, Kai, Pratilas, Christine A, Triche, Jr, Tim J, Graveel, Carrie R, Steensma, Matthew R

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NF1 deficiency drives metabolic reprogramming in ER+ breast cancer von House, Rachel (Rae) J., Tovar, Elizabeth A., Redlon, Luke N., Essenburg, Curt J., Dischinger, Patrick S., Ellis, Abigail E., Beddows, Ian, Sheldon, Ryan D., Lien, Evan C., Graveel, Carrie R., Steensma, Matthew R.

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Nf1 deficiency modulates the stromal environment in the pretumorigenic rat mammary gland von Arumugam, Menusha, Tovar, Elizabeth A, Essenburg, Curt J, Dischinger, Patrick S, Beddows, Ian, Wolfrum, Emily, Madaj, Zach B, Turner, Lisa, Feenstra, Kristin, Gallik, Kristin L, Cohen, Lorna, Nichols, Madison, Sheridan, Rachel T C, Esquibel, Corinne R, Mouneimne, Ghassan, Graveel, Carrie R, Steensma, Matthew R

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Ex Vivo Patient-Derived Explant Model for Neurofibromatosis Type 1–Related Cutaneous Neurofibromas von Grit, Jamie L., Turner, Lisa, Essenburg, Curt J., Gallik, Kristin L., Dischinger, Patrick S., Shurlow, Nathan D., Pate, Matthew J., Graveel, Carrie R., Steensma, Matthew R.

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p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs von Grit, Jamie L., McGee, Lauren E., Tovar, Elizabeth A., Essenburg, Curt J., Wolfrum, Emily, Beddows, Ian, Williams, Kaitlin, Sheridan, Rachael T. C., Schipper, Joshua L., Adams, Marie, Arumugam, Menusha, Vander Woude, Thomas, Gurunathan, Sharavana, Field, Jeffrey M., Wulfkuhle, Julia, Petricoin, Emanuel F., Graveel, Carrie R., Steensma, Matthew R.

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Cabozantinib (XL184) Inhibits Growth and Invasion of Preclinical TNBC Models von Sameni, Mansoureh, Tovar, Elizabeth A, Essenburg, Curt J, Chalasani, Anita, Linklater, Erik S, Borgman, Andrew, Cherba, David M, Anbalagan, Arulselvi, Winn, Mary E, Graveel, Carrie R, Sloane, Bonnie F

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Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers von Linklater, Erik S, Tovar, Elizabeth A, Essenburg, Curt J, Turner, Lisa, Madaj, Zachary, Winn, Mary E, Melnik, Marianne K, Korkaya, Hasan, Maroun, Christiane R, Christensen, James G, Steensma, Matthew R, Boerner, Julie L, Graveel, Carrie R

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NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer von Dischinger, Patrick S., Tovar, Elizabeth A., Essenburg, Curt J., Madaj, Zachary B., Gardner, Eve E., Callaghan, Megan E., Turner, Ashley N., Challa, Anil K., Kempston, Tristan, Eagleson, Bryn, Kesterson, Robert A., Bronson, Roderick T., Bowman, Megan J., Graveel, Carrie R., Steensma, Matthew R.

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Kinome Profiling of NF1-Related MPNSTs in Response to Kinase Inhibition and Doxorubicin Reveals Therapeutic Vulnerabilities von Grit, Jamie L, Pridgeon, Matt G, Essenburg, Curt J, Wolfrum, Emily, Madaj, Zachary B, Turner, Lisa, Wulfkuhle, Julia, Petricoin, 3rd, Emanuel F, Graveel, Carrie R, Steensma, Matthew R

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Dissecting the Rat Mammary Gland: Isolation, Characterization, and Culture of Purified Mammary Epithelial Cells and Fibroblasts von Tovar, Elizabeth A, Sheridan, Rachael, Essenburg, Curt J, Dischinger, Patrick S, Arumugam, Menusha, Callaghan, Megan E, Graveel, Carrie R, Steensma, Matthew R

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In vivo Efficacy Studies in Cell Line and Patient-derived Xenograft Mouse Models von Tovar, Elizabeth A, Essenburg, Curt J, Graveel, And Carrie

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Abstract B19: MET and IL6 signaling in triple-negative breast cancer von Tovar, Elizabeth A., Sameni, Mansoureh, Essenburg, Curt J., Chalasani, Anita, Linklater, Erik S., Cherba, David M., Anbalagan, Aruselvi, Winn, Mary E., Sloane, Bonnie F., Graveel, Carrie R.

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Abstract B14: Targeting the intratumoral heterogeneity of receptor tyrosine kinases in breast cancer von Tovar, Elizabeth A., Linklater, Erik S., Essenburg, Curt J., Madaj, Zach, Cherba, David M., Winn, Mary E., Korkaya, Hasan, Boerner, Julie L., Graveel, Carrie R.

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Additional file 6 of Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/p38 signaling von Grit, Jamie L., Johnson, Benjamin K., Dischinger, Patrick S., Essenburg, Curt J., Adams, Marie, Campbell, Stacy, Pollard, Kai, Pratilas, Christine A., Triche, Tim J., Graveel, Carrie R., Steensma, Matthew R.

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Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma von Xie, Qian, Bradley, Robert, Kang, Liang, Koeman, Julie, Ascierto, Maria Libera, Worschech, Andrea, De Giorgi, Valeria, Wang, Ena, Kefene, Lisa, Su, Yanli, Essenburg, Curt, Kaufman, Dafna W, DeKoning, Tom, Enter, Mark A, O'Rourke, Timothy J, Marincola, Francesco M, Vande Woude, George F

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Overexpression of HGF Promotes HBV-Induced Hepatocellular Carcinoma Progression and Is an Effective Indicator for Met-Targeting Therapy von Xie, Qian, Su, Yanli, Dykema, Karl, Johnson, Jennifer, Koeman, Julie, De Giorgi, Valeria, Huang, Alan, Schlegel, Robert, Essenburg, Curt, Kang, Liang, Iwaya, Keiichi, Seki, Shuhji, Khoo, Sok Kean, Zhang, Boheng, Buonaguro, Franco, Marincola, Francesco M, Furge, Kyle, Vande Woude, George F, Shinomiya, Nariyoshi

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