Breast cancer liver metastasis: current and future treatment approaches von Rashid, Narmeen S., Grible, Jacqueline M., Clevenger, Charles V., Harrell, J. Chuck

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A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis von Wagenblast, Elvin, Soto, Mar, Gutiérrez-Ángel, Sara, Hartl, Christina A., Gable, Annika L., Maceli, Ashley R., Erard, Nicolas, Williams, Alissa M., Kim, Sun Y., Dickopf, Steffen, Harrell, J. Chuck, Smith, Andrew D., Perou, Charles M., Wilkinson, John E., Hannon, Gregory J., Knott, Simon R. V.

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Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse von Harrell, J. Chuck, Prat, Aleix, Parker, Joel S., Fan, Cheng, He, Xiaping, Carey, Lisa, Anders, Carey, Ewend, Matthew, Perou, Charles M.

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Identification of synergistic drug combinations using breast cancer patient-derived xenografts von Turner, Tia H., Alzubi, Mohammad A., Harrell, J. Chuck

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A triple hormone receptor ER, AR, and VDR signature is a robust prognosis predictor in breast cancer von Omar, Mohamed, Harrell, J Chuck, Tamimi, Rulla, Marchionni, Luigi, Erdogan, Cihat, Nakshatri, Harikrishna, Ince, Tan A

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Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes von Prat, Aleix, Karginova, Olga, Parker, Joel S., Fan, Cheng, He, Xiaping, Bixby, Lisa, Harrell, J. Chuck, Roman, Erick, Adamo, Barbara, Troester, Melissa, Perou, Charles M.

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Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures von Kabos, Peter, Finlay-Schultz, Jessica, Li, Chunling, Kline, Enos, Finlayson, Christina, Wisell, Joshua, Manuel, Christopher A., Edgerton, Susan M., Harrell, J. Chuck, Elias, Anthony, Sartorius, Carol A.

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Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells von Dravis, Christopher, Spike, Benjamin T., Harrell, J. Chuck, Johns, Claire, Trejo, Christy L., Southard-Smith, E. Michelle, Perou, Charles M., Wahl, Geoffrey M.

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Metformin attenuates transforming growth factor beta (TGF-β) mediated oncogenesis in mesenchymal stem-like/claudin-low triple negative breast cancer von Wahdan-Alaswad, Reema, Harrell, J Chuck, Fan, Zeying, Edgerton, Susan M, Liu, Bolin, Thor, Ann D

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Taxonomy of breast cancer based on normal cell phenotype predicts outcome von Santagata, Sandro, Thakkar, Ankita, Ergonul, Ayse, Wang, Bin, Woo, Terri, Hu, Rong, Harrell, J Chuck, McNamara, George, Schwede, Matthew, Culhane, Aedin C, Kindelberger, David, Rodig, Scott, Richardson, Andrea, Schnitt, Stuart J, Tamimi, Rulla M, Ince, Tan A

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Serine residues 726 and 780 have nonredundant roles regulating STAT5a activity in luminal breast cancer von Woock, Alicia E., Grible, Jacqueline M., Olex, Amy L., Harrell, J. Chuck, Zot, Patricija, Idowu, Michael, Clevenger, Charles V.

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New generation breast cancer cell lines developed from patient-derived xenografts von Finlay-Schultz, Jessica, Jacobsen, Britta M., Riley, Duncan, Paul, Kiran V., Turner, Scott, Ferreira-Gonzalez, Andrea, Harrell, J. Chuck, Kabos, Peter, Sartorius, Carol A.

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The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumours von Lundberg, Arian, Lindström, Linda S, Li, Jingmei, Harrell, J Chuck, Darai-Ramqvist, Eva, Sifakis, Emmanouil G, Foukakis, Theodoros, Perou, Charles M, Czene, Kamila, Bergh, Jonas, Tobin, Nicholas P

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Gene Expression Signatures and Immunohistochemical Subtypes Add Prognostic Value to Each Other in Breast Cancer Cohorts von Lundberg, Arian, Lindström, Linda S, Harrell, J Chuck, Falato, Claudette, Carlson, Joseph W, Wright, Paul K, Foukakis, Theodoros, Perou, Charles M, Czene, Kamila, Bergh, Jonas, Tobin, Nicholas P

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Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer von Byers, Holly A., Brooks, Amy N., Vangala, Janakiram R., Grible, Jacqueline M., Feygin, Alex, Clevenger, Charles V., Harrell, J. Chuck, Radhakrishnan, Senthil K.

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SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer von Wang, Chu-An, Jedlicka, Paul, Patrick, Aaron N, Micalizzi, Douglas S, Lemmer, Kimberly C, Deitsch, Erin, Casás-Selves, Matias, Harrell, J Chuck, Ford, Heide L

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HDAC6 Deacetylates HMGN2 to Regulate Stat5a Activity and Breast Cancer Growth von Medler, Terry R, Craig, Justin M, Fiorillo, Alyson A, Feeney, Yvonne B, Harrell, J Chuck, Clevenger, Charles V

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Separation of breast cancer and organ microenvironment transcriptomes in metastases von Alzubi, Mohammad A, Turner, Tia H, Olex, Amy L, Sohal, Sahib S, Tobin, Nicholas P, Recio, Susana G, Bergh, Jonas, Hatschek, Thomas, Parker, Joel S, Sartorius, Carol A, Perou, Charles M, Dozmorov, Mikhail G, Harrell, J Chuck

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Exploitation of Sulfated Glycosaminoglycan Status for Precision Medicine of Triplatin in Triple-Negative Breast Cancer von Hampton, James D, Peterson, Erica J, Katner, Samantha J, Turner, Tia H, Alzubi, Mohammad A, Harrell, J Chuck, Dozmorov, Mikhail G, Turner, Joseph B McGee, Gigliotti, Pam J, Kraskauskiene, Vita, Shende, Mayuri, Idowu, Michael O, Puchalapalli, Madhavi, Hu, Bin, Litovchick, Larisa, Katsuta, Eriko, Takabe, Kazuaki, Farrell, Nicholas P, Koblinski, Jennifer E

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The utility of the “Glowing Head” mouse for breast cancer metastasis research von Alzubi, Mohammad A., Boyd, David C., Harrell, J. Chuck

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