Hypermethylation and global remodelling of DNA methylation is associated with acquired cisplatin resistance in testicular germ cell tumours von Fazal, Zeeshan, Singh, Ratnakar, Fang, Fang, Bikorimana, Emmanuel, Baldwin, Hannah, Corbet, Andrea, Tomlin, Megan, Yerby, Cliff, Adra, Nabil, Albany, Costantine, Lee, Sarah, Freemantle, Sarah J., Nephew, Kenneth P, Christensen, Brock C, Spinella, Michael J.

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Retinoids in cancer therapy and chemoprevention: promise meets resistance von Freemantle, Sarah J, Spinella, Michael J, Dmitrovsky, Ethan

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The Relationship between Typical Environmental Endocrine Disruptors and Kidney Disease von Zhang, Xing, Flaws, Jodi A, Spinella, Michael J, Irudayaraj, Joseph

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G0S2 Suppresses Oncogenic Transformation by Repressing a MYC-Regulated Transcriptional Program von Yim, Christina Y, Sekula, David J, Hever-Jardine, Mary P, Liu, Xi, Warzecha, Joshua M, Tam, Janice, Freemantle, Sarah J, Dmitrovsky, Ethan, Spinella, Michael J

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Reciprocal epigenetic remodeling controls testicular cancer hypersensitivity to hypomethylating agents and chemotherapy von Singh, Ratnakar, Fazal, Zeeshan, Bikorimana, Emmanuel, Boyd, Raya I., Yerby, Cliff, Tomlin, Megan, Baldwin, Hannah, Shokry, Doha, Corbet, Andrea K., Shahid, Khadeeja, Hattab, Aleyah, Freemantle, Sarah J., Spinella, Michael J.

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Per- and Polyfluoroalkyl Substance Exposure Combined with High-Fat Diet Supports Prostate Cancer Progression von Imir, Ozan Berk, Kaminsky, Alanna Zoe, Zuo, Qian-Ying, Liu, Yu-Jeh, Singh, Ratnakar, Spinella, Michael J, Irudayaraj, Joseph, Hu, Wen-Yang, Prins, Gail S, Madak Erdogan, Zeynep

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Refractory testicular germ cell tumors are highly sensitive to the targeting of polycomb pathway demethylases KDM6A and KDM6B von Shokry, Doha, Khan, Mehwish W, Powell, Christine, Johnson, Samantha, Rennels, Brayden C, Boyd, Raya I, Sun, Zhengyang, Fazal, Zeeshan, Freemantle, Sarah J, Parker, Maryanna H, Vieson, Miranda D, Samuelson, Jonathan P, Spinella, Michael J, Singh, Ratnakar

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Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine von Albany, Costantine, Hever-Jardine, Mary P, von Herrmann, Katherine M, Yim, Christina Y, Tam, Janice, Warzecha, Joshua M, Shin, Leah, Bock, Sarah E, Curran, Brian S, Chaudhry, Aneeq S, Kim, Fred, Sandusky, George E, Taverna, Pietro, Freemantle, Sarah J, Christensen, Brock C, Einhorn, Lawrence H, Spinella, Michael J

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Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation,... von Biswal, Bijesh K, Beyrouthy, Maroun J, Hever-Jardine, Mary P, Armstrong, David, Tomlinson, Craig R, Christensen, Brock C, Marsit, Carmen J, Spinella, Michael J

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High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors von Beyrouthy, Maroun J, Garner, Kristen M, Hever, Mary P, Freemantle, Sarah J, Eastman, Alan, Dmitrovsky, Ethan, Spinella, Michael J

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G0S2 promotes antiestrogenic and pro-migratory responses in ER+ and ER- breast cancer cells von Corbet, Andrea K., Bikorimana, Emmanuel, Boyd, Raya I., Shokry, Doha, Kries, Kelly, Gupta, Ayush, Paton, Anneliese, Sun, Zhengyang, Fazal, Zeeshan, Freemantle, Sarah J., Nelson, Erik R., Spinella, Michael J., Singh, Ratnakar

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Perfluorooctanesulfonic Acid Alters Pro-Cancer Phenotypes and Metabolic and Transcriptional Signatures in Testicular Germ Cell Tumors von Boyd, Raya I, Shokry, Doha, Fazal, Zeeshan, Rennels, Brayden C, Freemantle, Sarah J, La Frano, Michael R, Prins, Gail S, Madak Erdogan, Zeynep, Irudayaraj, Joseph, Singh, Ratnakar, Spinella, Michael J

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A p53-dominant transcriptional response to cisplatin in testicular germ cell tumor-derived human embyronal carcinoma von Kerley-Hamilton, Joanna S, Pike, Aimee M, Li, Na, DiRenzo, James, Spinella, Michael J

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Between a Rock and a Hard Place: An Epigenetic-Centric View of Testicular Germ Cell Tumors von Singh, Ratnakar, Fazal, Zeeshan, Freemantle, Sarah J, Spinella, Michael J

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Toward a Mechanistic Understanding of Poly- and Perfluoroalkylated Substances and Cancer von Boyd, Raya I, Ahmad, Saeed, Singh, Ratnakar, Fazal, Zeeshan, Prins, Gail S, Madak Erdogan, Zeynep, Irudayaraj, Joseph, Spinella, Michael J

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Headway and Hurdles in the Clinical Development of Dietary Phytochemicals for Cancer Therapy and Prevention: Lessons Learned from Vitamin A Derivatives von Yim, Christina Y., Mao, Pingping, Spinella, Michael J.

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Mechanisms of cisplatin sensitivity and resistance in testicular germ cell tumors von Singh, Ratnakar, Fazal, Zeeshan, Freemantle, Sarah J, Spinella, Michael J

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Nephrotoxicity of perfluorooctane sulfonate (PFOS)—effect on transcription and epigenetic factors von Wen, Yi, Rashid, Faizan, Fazal, Zeeshan, Singh, Ratnakar, Spinella, Michael J, Irudayaraj, Joseph

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The potential of retinoids for combination therapy of lung cancer: Updates and future directions von Tripathi, Surya Kant, Pandey, Kamal, Panda, Munmun, Spinella, Michael J., Rengasamy, Kannan RR, Biswal, Bijesh K

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Retinoic Acid Promotes Ubiquitination and Proteolysis of Cyclin D1 during Induced Tumor Cell Differentiation von Spinella, Michael J., Freemantle, Sarah J., Sekula, David, Chang, Jeffrey H., Christie, Allison J., Dmitrovsky, Ethan

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