The Promising Evolution of Targeted Therapeutic Strategies in Cancer von Peters, Solange, Mok, Tony, Passaro, Antonio, Jänne, Pasi Antero

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Success of genomic profiling of non–small cell lung cancer biopsies obtained by trans‐thoracic percutaneous needle biopsy von Gill, Ritu R., Murphy, David John, Kravets, Sasha, Sholl, Lynnette Mary, Janne, Pasi Antero, Johnson, Bruce Evan

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Discovery of a small-molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRα, Kit, and Src kinases: novel type II inhibitor of gatekeeper mutants von Weisberg, Ellen, Choi, Hwan Geun, Ray, Arghya, Barrett, Rosemary, Zhang, Jianming, Sim, Taebo, Zhou, Wenjun, Seeliger, Markus, Cameron, Michael, Azam, Mohammed, Fletcher, Jonathan A., Debiec-Rychter, Maria, Mayeda, Mark, Moreno, Daisy, Kung, Andrew L., Janne, Pasi Antero, Khosravi-Far, Roya, Melo, Junia V., Manley, Paul W., Adamia, Sophia, Wu, Catherine, Gray, Nathanael, Griffin, James D.

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Identification and Characterization of ALK Kinase Splicing Isoforms in Non–Small-Cell Lung Cancer von de Figueiredo-Pontes, Lorena Lobo, Wong, Daisy Wing-Sze, Tin, Vicky Pui-Chi, Chung, Lap-Ping, Yasuda, Hiroyuki, Yamaguchi, Norihiro, Nakayama, Sohei, Jänne, Pasi Antero, Wong, Maria Pik, Kobayashi, Susumu Soeda, Costa, Daniel Botelho

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Rationale and study design of ARCHER: a randomized, double-blind, Phase III study of dacomitinib versus erlotinib for advanced non-small-cell lung cancer von Boyer, Michael, Jänne, Pasi Antero, Mok, Tony, O’Byrne, Kenneth, Paz-Ares, Luis, Ramalingam, Suresh S, Liang, Jane, Taylor, Ian, Campbell, Alicyn, O’Connell, Joseph, Letrent, Stephen, Antic, Vladan

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MET Exon 14 Mutations in Non–Small-Cell Lung Cancer Are Associated With Advanced Age and Stage-Dependent MET Genomic Amplification and c-Met Overexpression von Awad, Mark Magdi, Oxnard, Geoffrey Raymond, Jackman, David M, Savukoski, Daniel O, Hall, Dimity, Shivdasani, Priyanka, Heng, Jennifer C, Dahlberg, Suzanne Eleanor, Janne, Pasi Antero, Verma, Suman, Christensen, James, Hammerman, Peter Seth, Sholl, Lynette Marie

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Medical management of pulmonary carcinoid tumors von Chong, Curtis Robert, Wirth, Lori J., Chen, Aileen B., Sholl, Lynette M., Janne, Pasi Antero, Johnson, Bruce E

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ROS1 Immunohistochemistry for Detection of ROS1-Rearranged Lung Adenocarcinomas von Sholl, Lynette Marie, Sun, Heather, Butaney, Mohit, Zhang, Chengsheng, Lee, Charles, Janne, Pasi Antero, Rodig, Scott J

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Volumetric tumor growth in advanced NSCLC patients (pts) with EGFR mutations during EGFR-TKI therapy: Developing criteria to define slow progression von Nishino, Mizuki, Dahlberg, Suzanne Eleanor, Cardarella, Stephanie, Jackman, David Michael, Rabin, Michael S., Ramaiya, Nikhil H., Hatabu, Hiroto, Janne, Pasi Antero, Johnson, Bruce E.

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Clinical, Pathologic, and Biologic Features Associated with BRAF Mutations in Non-Small Cell Lung Cancer von Cardarella, S, Ogino, Atsuko, Nishino, Michiya, Butaney, M, Shen, Jeanne, Lydon, C, Yeap, Beow Yong, Sholl, Lynette Marie, Johnson, Bruce Evan, Janne, Pasi Antero

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Chemotherapy for locally advanced and metastatic pulmonary carcinoid tumors von Chong, Curtis Robert, Wirth, Lori Julin, Nishino, Mizuki, Chen, Aileen Betty, Sholl, Lynette Marie, Kulke, Matthew H, McNamee, Ciaran, Janne, Pasi Antero, Johnson, Bruce Evan

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Radiographic assessment and therapeutic decisions at RECIST progression in EGFR-mutant NSCLC treated with EGFR tyrosine kinase inhibitors von Nishino, Mizuki, Heon, Stephanie, Dahlberg, Suzanne Eleanor, Jackman, David Michael, Ramaiya, Nikhil H., Hatabu, Hiroto, Rabin, Michael S., Janne, Pasi Antero, Johnson, Bruce E

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Genomic profiling of non-small cell lung cancer (NSCLC) for personalized targeted therapy using CT-guided transthoracic needle biopsy (TTNB) von Gill, Ritu R., Heon, Stephanie, Yeap, Beow Yong, Butaney, Mohit, Lindeman, Neal Ian, Rabin, Michael S., Jackman, David Michael, Janne, Pasi Antero, Johnson, Bruce E.

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First-line dacomitinib (PF-00299804), an irreversible pan-HER tyrosine kinase inhibitor, for patients with EGFR -mutant lung cancers von Kris, Mark G., Mok, Tony, Ou, Sai-Hong Ignatius, Martins, Renato, Kim, Dong-Wan, Goldberg, Zelanna, Zhang, Hui, Taylor, Ian, Letrent, Stephen P., Janne, Pasi Antero

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An analysis of the prevalence of HER2 and KRAS mutations, and ALK rearrangements and clinical outcomes in Cancer and Leukemia Group B [CALGB (Alliance)] trial 30406 in advanced non... von Stinchcombe, Tom, Sholl, Lynette M., Wang, Xiaofei F., Gu, Lin, Socinski, Mark A., Rodig, Scott J., Capelletti, Marzia, Crawford, Jeffrey, Edelman, Martin J., Villalona-Calero, Miguel Angel, Kratzke, Robert Arthur, Vokes, Everett E., Miller, Vincent A., Janne, Pasi Antero

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NTRK1 gene fusions as a novel oncogene target in lung cancer von Doebele, Robert Charles, Vaishnavi, Aria, Capelletti, Marzia, Le, Anh T., Kako, Severine, Butaney, Mohit, Mahale, Sakshi, Aisner, Dara L., Haas, Julia, Andrews, Steven W., Lipson, Doron, Stephens, Philip J., Varella-Garcia, Marileila, Janne, Pasi Antero, Miller, Vincent A.

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Discovery of recurrent KIF5B-RET fusions and other targetable alterations from clinical NSCLC specimens von Capelletti, Marzia, Lipson, Doron, Otto, Geoff, Yelensky, Roman, Ercan, Dalia, Kim, Jhingook, Sasaki, Hidefumi, Kim, Hyeong Ryul, Park, Seung-Il, Ross, Jeffrey S., Stephens, Philip, Cronin, Maureen T., Janne, Pasi Antero

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Prognostic and predictive effects of KRAS mutation subtype in completely resected non-small cell lung cancer (NSCLC): A LACE-bio study von Shepherd, Frances A., Bourredjem, Abderrahmane, Brambilla, Elisabeth, Domerg, Caroline, Douillard, Jean-Yves, Filipits, Martin, Graziano, Stephen L., Hainaut, Pierre, Janne, Pasi Antero, Le Chevalier, Thierry, Le Teuff, Gwenael, Pignon, Jean-Pierre, Pirker, Robert, Seymour, Lesley, Soria, Jean-Charles, Taron, Miquel, Tsao, Ming Sound

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EGFRMutation Is a Better Predictor of Response to Tyrosine Kinase Inhibitors in Non–Small Cell Lung Carcinoma Than FISH, CISH, and Immunohistochemistry von Sholl, Lynette Marie, Xiao, Yun, Joshi, Victoria, Yeap, Beow Yong, Cioffredi, Leigh-Anne, Jackman, David M, Lee, Charles, Janne, Pasi Antero, Lindeman, Neal I

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Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors von Akbay, E, Koyama, S, Carretero, J, Altabef, A, Tchaicha, J. H, Christensen, Camilla Laulund, Mikse, O. R, Cherniack, Andrew David, Beauchamp, Ellen Monica, Pugh, T, Wilkerson, M. D, Fecci, P, Butaney, M, Reibel, J. B, Soucheray, M, Cohoon, T. J, Janne, Pasi Antero, Meyerson, Matthew Langer, Hayes, D. N, Shapiro, Geoffrey Ira, Shimamura, T, Sholl, Lynette Marie, Rodig, Scott J, Freeman, Gordon James, Hammerman, Peter Seth, Dranoff, G, Wong, Kwok-Kin

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