SMARTCyp 3.0: enhanced cytochrome P450 site-of-metabolism prediction server von Olsen, Lars, Montefiori, Marco, Tran, Khanhvi Phuc, Jørgensen, Flemming Steen

Volltext

Prediction of cytochrome P450 mediated metabolism von Olsen, Lars, Oostenbrink, Chris, Jørgensen, Flemming Steen

Volltext

Differences between the GluD1 and GluD2 receptors revealed by GluD1 X‐ray crystallography, binding studies and molecular dynamics von Masternak, Magdalena, Koch, Angela, Laulumaa, Saara, Tapken, Daniel, Hollmann, Michael, Jørgensen, Flemming Steen, Kastrup, Jette Sandholm

Volltext

Study on the binding of Thioflavin T to β-sheet-rich and non-β-sheet cavities von Groenning, Minna, Olsen, Lars, van de Weert, Marco, Flink, James M., Frokjaer, Sven, Jørgensen, Flemming S.

Volltext

Both Reactivity and Accessibility Are Important in Cytochrome P450 Metabolism: A Combined DFT and MD Study of Fenamic Acids in BM3 Mutants von Leth, Rasmus, Ercig, Bogac, Olsen, Lars, Jørgensen, Flemming Steen

Volltext

Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase von Jensen, Simon Bo, Thodberg, Sara, Parween, Shaheena, Moses, Matias E., Hansen, Cecilie C., Thomsen, Johannes, Sletfjerding, Magnus B., Knudsen, Camilla, Del Giudice, Rita, Lund, Philip M., Castaño, Patricia R., Bustamante, Yanet G., Velazquez, Maria Natalia Rojas, Jørgensen, Flemming Steen, Pandey, Amit V., Laursen, Tomas, Møller, Birger Lindberg, Hatzakis, Nikos S.

Volltext

Salt Bridge Swapping in the EXXERFXYY Motif of Proton-coupled Oligopeptide Transporters von Aduri, Nanda G., Prabhala, Bala K., Ernst, Heidi A., Jørgensen, Flemming S., Olsen, Lars, Mirza, Osman

Volltext

An Optimized Screen Reduces the Number of GA Transporters and Provides Insights Into Nitrate Transporter 1/Peptide Transporter Family Substrate Determinants von Wulff, Nikolai, Ernst, Heidi Asschenfeldt, Jørgensen, Morten Egevang, Lambertz, Sophie, Maierhofer, Tobias, Belew, Zeinu Mussa, Crocoll, Christoph, Motawia, Mohammed Saddik, Geiger, Dietmar, Jørgensen, Flemming Steen, Mirza, Osman, Nour-Eldin, Hussam Hassan

Volltext

Aldehyde Oxidase: Reaction Mechanism and Prediction of Site of Metabolism von Montefiori, Marco, Jørgensen, Flemming Steen, Olsen, Lars

Volltext

Synthesis and Structure-Activity Relationships of Novel Non-Steroidal CYP17A1 Inhibitors as Potential Prostate Cancer Agents von Wróbel, Tomasz M, Rogova, Oksana, Sharma, Katyayani, Rojas Velazquez, Maria Natalia, Pandey, Amit V, Jørgensen, Flemming Steen, Arendrup, Frederic S, Andersen, Kasper L, Björkling, Fredrik

Volltext

Itraconazole Reverts ABCB1-Mediated Docetaxel Resistance in Prostate Cancer von Lima, Thiago S., Souza, Luciano O., Iglesias-Gato, Diego, Elversang, Johanna, Jørgensen, Flemming Steen, Kallunki, Tuula, Røder, Martin A., Brasso, Klaus, Moreira, José M.A.

Volltext

The anti-epileptic drug lamotrigine inhibits the CYP17A1 lyase reaction in vitro von Munkboel, Cecilie Hurup, Christensen, Lise Rudbæk, Islin, Julie, Bonomo, Silvia, Olsen, Lars, Jørgensen, Flemming Steen, Styrishave, Bjarne

Volltext

Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents von Wróbel, Tomasz M, Rogova, Oksana, Andersen, Kasper L, Yadav, Rahul, Brixius-Anderko, Simone, Scott, Emily E, Olsen, Lars, Jørgensen, Flemming Steen, Björkling, Fredrik

Volltext

Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol von Frydenvang, Karla, Verkade-Vreeker, Marlies C A, Dohmen, Floor, Commandeur, Jan N M, Rafiq, Maria, Mirza, Osman, Jørgensen, Flemming Steen, Geerke, Daan P

Volltext

Virtual Screening and Prediction of Site of Metabolism for Cytochrome P450 1A2 Ligands von Vasanthanathan, Poongavanam, Hritz, Jozef, Taboureau, Olivier, Olsen, Lars, Steen Jørgensen, Flemming, Vermeulen, Nico P. E, Oostenbrink, Chris

Volltext

Effect of Essential Oil Components on the Activity of Steroidogenic Cytochrome P450 von Sharma, Katyayani, Lanzilotto, Angelo, Yakubu, Jibira, Therkelsen, Søren, Vöegel, Clarissa Daniela, Du Toit, Therina, Jørgensen, Flemming Steen, Pandey, Amit V

Volltext

A steered molecular dynamics study of binding and translocation processes in the GABA transporter von Skovstrup, Søren, David, Laurent, Taboureau, Olivier, Jørgensen, Flemming Steen

Volltext

Classification of Cytochrome P450 1A2 Inhibitors and Noninhibitors by Machine Learning Techniques von Vasanthanathan, Poongavanam, Taboureau, Olivier, Oostenbrink, Chris, Vermeulen, Nico P.E., Olsen, Lars, Jørgensen, Flemming Steen

Volltext

Geometry of the canonical Van Vleck transformation part II: Further developments and numerical treatment von Jørgensen, Flemming

Volltext

hERG Classification Model Based on a Combination of Support Vector Machine Method and GRIND Descriptors von Li, Qiyuan, Jørgensen, Flemming Steen, Oprea, Tudor, Brunak, Søren, Taboureau, Olivier

Volltext