Comment on: Hölscher AH, Bollschweiler E, Bogoevski D, Schmidt H, Semrau R, Izbicki JR. Prognostic impact of neoadjuvant chemoradiation in cT3 oesophageal cancer – A propensity score matched analysis. Eur J Cancer. 2014;50(17):2950–7 von van Rossum, Peter S.N, Goense, Lucas, van Hillegersberg, Richard, Ruurda, Jelle P

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Reply to the Comment on: Hölscher AH, Bollschweiler E, Bogoevski D, Schmidt H, Semrau R, Izbicki JR. Prognostic impact of neoadjuvant chemoradiation in cT3 oesophageal cancer – A propensity score matched analysis. Eur J Cancer. 2014;50(17):2950–7 von Bollschweiler, Elfriede, Hölscher, Arnulf H

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TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer von Perez, Laura Garcia, Kempski, Jan, McGee, Heather M., Pelzcar, Penelope, Agalioti, Theodora, Giannou, Anastasios, Konczalla, Leonie, Brockmann, Leonie, Wahib, Ramez, Xu, Hao, Vesely, Maria Carolina Amezcua, Soukou, Shiwa, Steglich, Babett, Bedke, Tanja, Manthey, Carolin, Seiz, Oliver, Diercks, Björn-Philipp, Gnafakis, Stylianos, Guse, Andreas H., Perez, Daniel, Izbicki, Jakob R., Gagliani, Nicola, Flavell, Richard A., Huber, Samuel

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Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid vs Gemcitabine Following Pancreatic Cancer Resection: A Randomized Controlled Trial von Neoptolemos, John P, Stocken, Deborah D, Bassi, Claudio, Ghaneh, Paula, Cunningham, David, Goldstein, David, Padbury, Robert, Moore, Malcolm J, Gallinger, Steven, Mariette, Christophe, Wente, Moritz N, Izbicki, Jakob R, Friess, Helmut, Lerch, Markus M, Dervenis, Christos, Oláh, Attila, Butturini, Giovanni, Doi, Ryuichiro, Lind, Pehr A, Smith, David, Valle, Juan W, Palmer, Daniel H, Buckels, John A, Thompson, Joyce, McKay, Colin J, Rawcliffe, Charlotte L, Büchler, Markus W, European Study Group for Pancreatic Cancer, for the

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Is the Whipple Procedure Harmful for Long-term Outcome in Treatment of Chronic Pancreatitis? 15-Years Follow-up Comparing the Outcome after Pylorus-Preserving Pancreatoduodenectomy... von Bachmann, Kai, Tomkoetter, Lena, Kutup, Asad, Erbes, Johannes, Vashist, Yogesh, Mann, Oliver, Bockhorn, Maximilian, Izbicki, Jakob R

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Optimal Duration and Timing of Adjuvant Chemotherapy After Definitive Surgery for Ductal Adenocarcinoma of the Pancreas: Ongoing Lessons From the ESPAC-3 Study von VALLE, Juan W, PALMER, Daniel, O'REILLY, Derek, GOLDSTEIN, David, ROBINSON, Bridget A, KARAPETIS, Christos, SCARFE, Andrew, LACAINE, Francois, SAND, Juhani, IZBICKI, Jakob R, MAYERLE, Julia, DERVENIS, Christos, JACKSON, Richard, OLAH, Attila, BUTTURINI, Giovanni, LIND, Pehr A, MIDDLETON, Mark R, ANTHONEY, Alan, SUMPTER, Kate, CARTER, Ross, BÜCHLER, Markus W, COX, Trevor, NEOPTOLEMOS, John P, GHANEH, Paula, RAWCLIFFE, Charlotte L, BASSI, Claudio, STOCKEN, Deborah D, CUNNINGHAM, David

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Patterns of Recurrence After Resection of Pancreatic Ductal Adenocarcinoma: A Secondary Analysis of the ESPAC-4 Randomized Adjuvant Chemotherapy Trial von Jones, Robert P, Psarelli, Eftychia-Eirini, Jackson, Richard, Ghaneh, Paula, Halloran, Christopher M, Palmer, Daniel H, Campbell, Fiona, Valle, Juan W, Faluyi, Olusola, O’Reilly, Derek A, Cunningham, David, Wadsley, Jonathan, Darby, Suzanne, Meyer, Tim, Gillmore, Roopinder, Anthoney, Alan, Lind, Pehr, Glimelius, Bengt, Falk, Stephen, Izbicki, Jakob R, Middleton, Gary William, Cummins, Sebastian, Ross, Paul J, Wasan, Harpreet, McDonald, Alec, Crosby, Tom, Ting, Yuk, Patel, Kinnari, Sherriff, David, Soomal, Rubin, Borg, David, Sothi, Sharmila, Hammel, Pascal, Lerch, Markus M, Mayerle, Julia, Tjaden, Christine, Strobel, Oliver, Hackert, Thilo, Büchler, Markus W, Neoptolemos, John P

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Molecular and functional heterogeneity of IL-10-producing CD4+ T cells von Brockmann, Leonie, Soukou, Shiwa, Steglich, Babett, Czarnewski, Paulo, Zhao, Lilan, Wende, Sandra, Bedke, Tanja, Ergen, Can, Manthey, Carolin, Agalioti, Theodora, Geffken, Maria, Seiz, Oliver, Parigi, Sara M., Sorini, Chiara, Geginat, Jens, Fujio, Keishi, Jacobs, Thomas, Roesch, Thomas, Izbicki, Jacob R., Lohse, Ansgar W., Flavell, Richard A., Krebs, Christian, Gustafsson, Jan-Ake, Antonson, Per, Roncarolo, Maria Grazia, Villablanca, Eduardo J., Gagliani, Nicola, Huber, Samuel

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European experts consensus statement on cystic tumours of the pancreas von Del Chiaro, Marco, Verbeke, Caroline, Salvia, Roberto, Klöppel, Gunter, Werner, Jens, McKay, Colin, Friess, Helmut, Manfredi, Riccardo, Van Cutsem, Eric, Löhr, Matthias, Segersvärd, Ralf

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Systemic interleukin 10 levels indicate advanced stages while interleukin 17A levels correlate with reduced survival in esophageal adenocarcinomas von Karstens, Karl-Frederick, Kempski, Jan, Giannou, Anastasios D, Freiwald, Erik, Reeh, Matthias, Tachezy, Michael, Izbicki, Jakob R, Lohse, Ansgar W, Gagliani, Nicola, Huber, Samuel, Pelczar, Penelope

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Minimal dissemination of solid epithelial tumours: Impact on staging and therapeutic strategy von Izbicki, J. R., Hosch, S. B.

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Short-term dietary changes can result in mucosal and systemic immune depression von Siracusa, Francesco, Schaltenberg, Nicola, Kumar, Yogesh, Lesker, Till R., Steglich, Babett, Liwinski, Timur, Cortesi, Filippo, Frommann, Laura, Diercks, Björn-Phillip, Bönisch, Friedericke, Fischer, Alexander W., Scognamiglio, Pasquale, Pauly, Mira J., Casar, Christian, Cohen, Yotam, Pelczar, Penelope, Agalioti, Theodora, Delfs, Flemming, Worthmann, Anna, Wahib, Ramez, Jagemann, Bettina, Mittrücker, Hans-Willi, Kretz, Oliver, Guse, Andreas H., Izbicki, Jakob R., Lassen, Kara G., Strowig, Till, Schweizer, Michaela, Villablanca, Eduardo J., Elinav, Eran, Huber, Samuel, Heeren, Joerg, Gagliani, Nicola

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Short-term Results of a Randomized Controlled Trial Comparing Primary Suture With Primary Glued Mesh Augmentation to Prevent Incisional Hernia von Timmermans, Lucas, Eker, Hasan H, Steyerberg, Ewout W, Jairam, An, de Jong, Diederik, Pierik, E. G. J M, Lases, S S, van der Ham, Arie C, Dawson, Imro, Charbon, Jan, Schuhmacher, Christoph, Izbicki, Jakob R, Neuhaus, Peter, Knebel, Peter, Fortelny, Rene, Kleinrensink, Gert-Jan, Jeekel, Johannes, Lange, Johan F

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Anti-inflammatory microenvironment of esophageal adenocarcinomas negatively impacts survival von Karstens, Karl-Frederick, Kempski, Jan, Giannou, Anastasios D., Pelczar, Penelope, Steglich, Babett, Steurer, Stefan, Freiwald, Eric, Woestemeier, Anna, Konczalla, Leonie, Tachezy, Michael, Reeh, Matthias, Bockhorn, Maximilian, Perez, Daniel, Mann, Oliver, Lohse, Ansgar W., Roesch, Thomas, Izbicki, Jakob R., Gagliani, Nicola, Huber, Samuel

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Tumour diameter is not reliable for management of non-secreting pancreatic neuroendocrine tumours von Frilling, A, Mills, L, Drymousis, P, Vashist, Y, Burdelski, C, Prachalias, A, Srinivasan, P, Menon, K, Cotoi, C, Khan, S, Cave, J, Armstrong, T, Weickert, MO, Izbicki, JR, Schrader, J, Ramage, JK, Srirajaskanthan, S

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Sex-Specific Genetic Associations for Barrett’s Esophagus and Esophageal Adenocarcinoma von Dong, Jing, Maj, Carlo, Tsavachidis, Spiridon, Ostrom, Quinn T., Gharahkhani, Puya, Anderson, Lesley A., Wu, Anna H., Ye, Weimin, Bernstein, Leslie, Borisov, Oleg, Schröder, Julia, Chow, Wong-Ho, Gammon, Marilie D., Liu, Geoffrey, Caldas, Carlos, Pharoah, Paul D., Risch, Harvey A., May, Andrea, Gerges, Christian, Anders, Mario, Venerito, Marino, Schmidt, Thomas, Izbicki, Jakob R., Hölscher, Arnulf H., Schumacher, Brigitte, Vashist, Yogesh, Neuhaus, Horst, Rösch, Thomas, Knapp, Michael, Krawitz, Peter, Böhmer, Anne, Iyer, Prasad G., Reid, Brian J., Lagergren, Jesper, Shaheen, Nicholas J., Corley, Douglas A., Gockel, Ines, Fitzgerald, Rebecca C., Dong, Jing, Maj, Carlo, Tsavachidis, Spiridon, Ostrom, Quinn T., Gharahkhani, Puya, Anderson, Lesley A., Wu, Anna H., Ye, Weimin, Bernstein, Leslie, Borisov, Oleg, Schröder, Julia, Chow, Wong-Ho, Gammon, Marilie D., Liu, Geoffrey, Caldas, Carlos, Pharoah, Paul D., Risch, Harvey A., May, Andrea, Gerges, Christian, Anders, Mario, Venerito, Marino, Schmidt, Thomas, Izbicki, Jakob R., Hölscher, Arnulf H., Schumacher, Brigitte, Vashist, Yogesh, Neuhaus, Horst, Rösch, Thomas, Knapp, Michael, Krawitz, Peter, Böhmer, Anne, Iyer, Prasad G., Reid, Brian J., Lagergren, Jesper, Shaheen, Nicholas J., Corley, Douglas A., Gockel, Ines, Fitzgerald, Rebecca C., Cook, Michael B., Whiteman, David C., Vaughan, Thomas L., Schumacher, Johannes, Thrift, Aaron P., Cook, Michael B., Whiteman, David C., Vaughan, Thomas L., Schumacher, Johannes, Thrift, Aaron P.

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Colorectal Carcinoma: Impact of Staging on Surgical Treatment von Izbicki, J. R., Blöchle, C.

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Altered PTEN function caused by deletion or gene disruption is associated with poor prognosis in rectal but not in colon cancer von Bohn, B.A., MD, Mina, S., MD, Krohn, A., MSc, Simon, R., PhD, Kluth, M., MSc, Harasimowicz, S, Quaas, A., MD, Bockhorn, M., MD, Izbicki, J.R., MD, Sauter, G., MD, Marx, A., MD, Stahl, P.R., MD

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