Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance von Serasinghe, M N, Missert, D J, Asciolla, J J, Podgrabinska, S, Wieder, S Y, Izadmehr, S, Belbin, G, Skobe, M, Chipuk, J E

Volltext

Sensitization to the mitochondrial pathway of apoptosis augments melanoma tumor cell responses to conventional chemotherapeutic regimens von Anvekar, R A, Asciolla, J J, Lopez-Rivera, E, Floros, K V, Izadmehr, S, Elkholi, R, Belbin, G, Sikora, A G, Chipuk, J E

Volltext

PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells von Kauko, O, O'Connor, CM, Kulesskiy, E, Sangodkar, J, Aakula, A, Izadmehr, S, Yetukuri, L, Yadav, B, Padzik, A, Laajala, TD, Haapaniemi, P, Momeny, M, Varila, T, Ohlmeyer, M, Aittokallio, T, Wennerberg, K, Narla, G, Westermarck, J

Volltext

Myeloid Cell-associated Resistance to PD-1/PD-L1 Blockade in Urothelial Cancer Revealed Through Bulk and Single-cell RNA Sequencing von Wang, Li, Sfakianos, John P., Beaumont, Kristin G., Akturk, Guray, Horowitz, Amir, Sebra, Robert P., Farkas, Adam M., Gnjatic, Sacha, Hake, Austin, Izadmehr, Sudeh, Wiklund, Peter, Oh, William K., Szabo, Peter M., Wind-Rotolo, Megan, Unsal-Kacmaz, Keziban, Yao, Xin, Schadt, Eric, Sharma, Padmanee, Bhardwaj, Nina, Zhu, Jun, Galsky, Matthew D.

Volltext

NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer von Salomé, Bérengère, Sfakianos, John P, Ranti, Daniel, Daza, Jorge, Bieber, Christine, Charap, Andrew, Hammer, Christian, Banchereau, Romain, Farkas, Adam M, Ruan, Dan Fu, Izadmehr, Sudeh, Geanon, Daniel, Kelly, Geoffrey, de Real, Ronaldo M, Lee, Brian, Beaumont, Kristin G, Shroff, Sanjana, Wang, Yuanshuo A, Wang, Ying-Chih, Thin, Tin Htwe, Garcia-Barros, Monica, Hegewisch-Solloa, Everardo, Mace, Emily M, Wang, Li, O'Donnell, Timothy, Chowell, Diego, Fernandez-Rodriguez, Ruben, Skobe, Mihaela, Taylor, Nicole, Kim-Schulze, Seunghee, Sebra, Robert P, Palmer, Doug, Clancy-Thompson, Eleanor, Hammond, Scott, Kamphorst, Alice O, Malmberg, Karl-Johan, Marcenaro, Emanuela, Romero, Pedro, Brody, Rachel, Viard, Mathias, Yuki, Yuko, Martin, Maureen, Carrington, Mary, Mehrazin, Reza, Wiklund, Peter, Mellman, Ira, Mariathasan, Sanjeev, Zhu, Jun, Galsky, Matthew D, Bhardwaj, Nina, Horowitz, Amir

Volltext

Factor XII and uPAR upregulate neutrophil functions to influence wound healing von Stavrou, Evi X, Fang, Chao, Bane, Kara L, Long, Andy T, Naudin, Clément, Kucukal, Erdem, Gandhi, Agharnan, Brett-Morris, Adina, Mumaw, Michele M, Izadmehr, Sudeh, Merkulova, Alona, Reynolds, Cindy C, Alhalabi, Omar, Nayak, Lalitha, Yu, Wen-Mei, Qu, Cheng-Kui, Meyerson, Howard J, Dubyak, George R, Gurkan, Umut A, Nieman, Marvin T, Sen Gupta, Anirban, Renné, Thomas, Schmaier, Alvin H

Volltext

Bisphosphonates inactivate human EGFRs to exert antitumor actions von Yuen, Tony, Stachnik, Agnes, Iqbal, Jameel, Sgobba, Miriam, Gupta, Yogesh, Lu, Ping, Colaianni, Graziana, Ji, Yaoting, Zhu, Ling-Ling, Kim, Se-Min, Li, Jianhua, Liu, Peng, Izadmehr, Sudeh, Sangodkar, Jaya, Bailey, Jack, Latif, Yathin, Mujtaba, Shiraz, Epstein, Solomon, Davies, Terry F., Bian, Zhuan, Zallone, Alberta, Aggarwal, Aneel K., Haider, Shozeb, New, Maria I., Sun, Li, Narla, Goutham, Zaidi, Mone

Volltext

Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer von Stachnik, Agnes, Yuen, Tony, Iqbal, Jameel, Sgobba, Miriam, Gupta, Yogesh, Lu, Ping, Colaianni, Graziana, Ji, Yaoting, Zhu, Ling-Ling, Kim, Se-Min, Li, Jianhua, Liu, Peng, Izadmehr, Sudeh, Sangodkar, Jaya, Scherer, Thomas, Mujtaba, Shiraz, Galsky, Matthew, Gomez, Jorge, Epstein, Solomon, Buettner, Christoph, Bian, Zhuan, Zallone, Alberta, Aggarwal, Aneel K., Haider, Shozeb, New, Maria I., Sun, Li, Narla, Goutham, Zaidi, Mone

Volltext

The Evolving Clinical Management of Genitourinary Cancers Amid the COVID-19 Pandemic von Izadmehr, Sudeh, Lundon, Dara J., Mohamed, Nihal, Katims, Andrew, Patel, Vaibhav, Eilender, Benjamin, Mehrazin, Reza, Badani, Ketan K., Sfakianos, John P., Tsao, Che-Kai, Wiklund, Peter, Oh, William K., Cordon-Cardo, Carlos, Tewari, Ashutosh K., Galsky, Matthew D., Kyprianou, Natasha

Volltext

Anti-apoptotic BCL-2 proteins govern cellular outcome following [B-RAF.sup.V600E] inhibition and can be targeted to reduce resistance von Serasinghe, M.N, Missert, D.J, Asciolla, J.J, Podgrabinska, S, Wieder, S.Y, Izadmehr, S, Belbin, G, Skobe, M, Chipuk, J.E

Volltext

Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF super(V600E) inhibition and can be targeted to reduce resistance von Serasinghe, M N, Missert, D J, Asciolla, J J, Podgrabinska, S, Wieder, S Y, Izadmehr, S, Belbin, G, Skobe, M, Chipuk, J E

Volltext

Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAFV600E inhibition and can be targeted to reduce resistance von Serasinghe, M N, Missert, D J, Asciolla, J J, Podgrabinska, S, Wieder, S Y, Izadmehr, S, Belbin, G, Skobe, M, Chipuk, J E

Volltext

Blocking FSH induces thermogenic adipose tissue and reduces body fat von Liu, P., Ji, Y.T., Yuen, T., Rendina-Ruedy, E., DeMambro, V.E., Dhawan, S., Abu-Amer, W., Izadmehr, S., Zhou, B., Shin, A.C., Latif, R., Thangeswaran, P., Gupta, A., Li, J.H., Shnayder, V., Robinson, S.T., Yu, Y.E., Zhang, X.J., Yang, F.R., Lu, P., Zhou, Y., Zhu, L.L., Oberlin, D.J., Davies, T.F., Reagan, M.R., Brown, A., Kumar, T.R., Epstein, S., Iqbal, J., Avadhani, N.G., New, M.I., Molina, H., Klinken, J.B. van, Guo, E.X., Buettner, C., Haider, S., Bian, Z., Sun, L., Rosen, C.J., Zaidi, M.

Volltext bestellen

Blocking FSH induces thermogenic adipose tissue and reduces body fat von Liu, P, Ji, Y, Yuen, T, Rendina-Ruedy, E, DeMambro, VE, Dhawan, S, Abu-Amer, W, Izadmehr, S, Zhou, B, Shin, AC, Latif, R, Thangeswaran, P, Gupta, A, Li, J, Shnayder, V, Robinson, ST, Yu, YE, Zhang, X, Yang, F, Lu, P, Zhou, Y, Zhu, L-L, Oberlin, DJ, Davies, TF, Reagan, MR, Brown, A, Kumar, TR, Epstein, S, Iqbal, J, Avadhani, NG, New, MI, Molina, H, van Klinken, JB, Guo, EX, Buettner, C, Haider, S, Bian, Z, Sun, L, Rosen, CJ, Zaidi, M

Volltext bestellen

Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth von Sangodkar, J, Perl, A, Tohme, R, Kiselar, J, Kastrinsky, DB, Zaware, N, Izadmehr, S, Mazhar, S, Wiredja, DD, O’Connor, CM, Hoon, D, Dhawan, NS, Schlatzer, D, Yao, S, Leonard, D, Borczuk, AC, Gokulrangan, G, Wang, L, Svenson, E, Farrington, CC, Yuan, E, Avelar, RA, Stachnik, A, Smith, B, Gidwani, V, Giannini, HM, McQuaid, D, McClinch, K, Wang, Z, Levine, AC, Sears, RC, Chen, EY, Duan, Q, Datt, M, Haider, S, Ma’ayan, A, DiFeo, A, Sharma, N, Galsky, MD, Brautigan, DL, Ioannou, YA, Xu, W, Chance, MR, Ohlmeyer, M, Narla, G

Volltext bestellen

Inhibitory Input from the Lateral Hypothalamus to the Ventral Tegmental Area Disinhibits Dopamine Neurons and Promotes Behavioral Activation von Nieh, Edward H., Vander Weele, Caitlin M., Matthews, Gillian A., Presbrey, Kara N., Wichmann, Romy, Leppla, Christopher A., Izadmehr, Ehsan M., Tye, Kay M.

Volltext

Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning von Allsop, Stephen A., Wichmann, Romy, Mills, Fergil, Burgos-Robles, Anthony, Chang, Chia-Jung, Felix-Ortiz, Ada C., Vienne, Alienor, Beyeler, Anna, Izadmehr, Ehsan M., Glober, Gordon, Cum, Meghan I., Stergiadou, Johanna, Anandalingam, Kavitha K., Farris, Kathryn, Namburi, Praneeth, Leppla, Christopher A., Weddington, Javier C., Nieh, Edward H., Smith, Anne C., Ba, Demba, Brown, Emery N., Tye, Kay M.

Volltext

Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment von Burgos-Robles, Anthony, Kimchi, Eyal Y, Izadmehr, Ehsan M, Porzenheim, Mary Jane, Ramos-Guasp, William A, Nieh, Edward H, Felix-Ortiz, Ada C, Namburi, Praneeth, Leppla, Christopher A, Presbrey, Kara N, Anandalingam, Kavitha K, Pagan-Rivera, Pablo A, Anahtar, Melodi, Beyeler, Anna, Tye, Kay M

Volltext

Dorsal Raphe Dopamine Neurons Represent the Experience of Social Isolation von Matthews, Gillian A., Nieh, Edward H., Vander Weele, Caitlin M., Halbert, Sarah A., Pradhan, Roma V., Yosafat, Ariella S., Glober, Gordon F., Izadmehr, Ehsan M., Thomas, Rain E., Lacy, Gabrielle D., Wildes, Craig P., Ungless, Mark A., Tye, Kay M.

Volltext

COVID-19: Therapeutics and Their Toxicities von Chary, Michael A., Barbuto, Alexander F., Izadmehr, Sudeh, Hayes, Bryan D., Burns, Michele M.

Volltext