A systematic screen of FDA-approved drugs for inhibitors of biological threat agents von Madrid, Peter B, Chopra, Sidharth, Manger, Ian D, Gilfillan, Lynne, Keepers, Tiffany R, Shurtleff, Amy C, Green, Carol E, Iyer, Lalitha V, Dilks, Holli Hutcheson, Davey, Robert A, Kolokoltsov, Andrey A, Carrion, Jr, Ricardo, Patterson, Jean L, Bavari, Sina, Panchal, Rekha G, Warren, Travis K, Wells, Jay B, Moos, Walter H, Burke, Raelyn L, Tanga, Mary J

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Structure-based lead optimization to improve antiviral potency and ADMET properties of phenyl-1H-pyrrole-carboxamide entry inhibitors targeted to HIV-1 gp120 von Curreli, Francesca, Belov, Dmitry S., Kwon, Young Do, Ramesh, Ranjith, Furimsky, Anna M., O'Loughlin, Kathleen, Byrge, Patricia C., Iyer, Lalitha V., Mirsalis, Jon C., Kurkin, Alexander V., Altieri, Andrea, Debnath, Asim K.

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Genetic Variants in the UDP-glucuronosyltransferase 1A1 Gene Predict the Risk of Severe Neutropenia of Irinotecan von INNOCENTI, Federico, UNDEVIA, Samir D, VOKES, Everett E, RATAIN, Mark J, IYER, Lalitha, PEI XIAN CHEN, DAS, Soma, KOCHERGINSKY, Masha, KARRISON, Theodore, JANISCH, Linda, RAMIREZ, Jacqueline, RUDIN, Charles M

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In Vitro Metabolism and Stability of the Actinide Chelating Agent 3,4,3-LI(1,2-HOPO) von Choi, Taylor A., Furimsky, Anna M., Swezey, Robert, Bunin, Deborah I., Byrge, Patricia, Iyer, Lalitha V., Chang, Polly Y., Abergel, Rebecca J.

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Development of a New Generation of 4-Aminoquinoline Antimalarial Compounds Using Predictive Pharmacokinetic and Toxicology Models von Ray, Sunetra, Madrid, Peter B, Catz, Paul, LeValley, Susanna E, Furniss, Michael J, Rausch, Linda L, Guy, R. Kiplin, DeRisi, Joseph L, Iyer, Lalitha V, Green, Carol E, Mirsalis, Jon C

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Endoscopic placement of the small-bowel video capsule by using a capsule endoscope delivery device von Holden, Jeremy P., MD, Dureja, Parul, MD, Pfau, Patrick R., MD, Schwartz, Darren C., MD, Reichelderfer, Mark, MD, Judd, Robert H., MD, Danko, Istvan, MD, PhD, Iyer, Lalitha V., MBBS, MD, Gopal, Deepak V., MD, FRCP(C), FACP

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Discovery and Optimization of Benzotriazine Di-N-Oxides Targeting Replicating and Nonreplicating Mycobacterium tuberculosis von Chopra, Sidharth, Koolpe, Gary A, Tambo-ong, Arlyn A, Matsuyama, Karen N, Ryan, Kenneth J, Tran, Tran B, Doppalapudi, Rupa S, Riccio, Edward S, Iyer, Lalitha V, Green, Carol E, Wan, Baojie, Franzblau, Scott G, Madrid, Peter B

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Unraveling the Aflatoxin−FAPY Conundrum:  Structural Basis for Differential Replicative Processing of Isomeric Forms of the Formamidopyrimidine-Type DNA Adduct of Aflatoxin B1 von Brown, Kyle L, Deng, James Z, Iyer, Rajkumar S, Iyer, Lalitha G, Voehler, Markus W, Stone, Michael P, Harris, Constance M, Harris, Thomas M

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Lead Optimization of Antimalarial Propafenone Analogues von Lowes, David, Pradhan, Anupam, Iyer, Lalitha V, Parman, Toufan, Gow, Jason, Zhu, Fangyi, Furimsky, Anna, Lemoff, Andrew, Guiguemde, W. Armand, Sigal, Martina, Clark, Julie A, Wilson, Emily, Tang, Liang, Connelly, Michele C, DeRisi, Joseph L, Kyle, Dennis E, Mirsalis, Jon, Guy, R. Kiplin

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Glucuronidation of trans-resveratrol by human liver and intestinal microsomes and UGT isoforms von Brill, Shirley S., Furimsky, Anna M., Ho, Mark N., Furniss, Michael J., Li, Yi, Green, Adam G., Green, Carol E., Iyer, Lalitha V., Bradford, Wallace W., Kapetanovic, Izet M.

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The Stereoselective Sulfate Conjugation of 4′-Methoxyfenoterol Stereoisomers by Sulfotransferase Enzymes von Iyer, Lalitha V., Ramamoorthy, Anuradha, Rutkowska, Ewelina, Furimsky, Anna M., Tang, Liang, Catz, Paul, Green, Carol E., Jozwiak, Krzysztof, Wainer, Irving W.

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Flavopiridol Metabolism in Cancer Patients Is Associated with the Occurrence of Diarrhea von INNOCENTI, Federico, STADLER, Walter M, IYER, Lalitha, RAMIREZ, Jacqueline, VOKES, Everett E, RATAIN, Mark J

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Biliary transport of irinotecan and metabolites in normal and P-glycoprotein-deficient mice von IYER, Lalitha, RAMIREZ, Jacqueline, SHEPARD, Dale R, BINGHAM, Christopher M, HOSSFELD, Dieter-Kurt, RATAIN, Mark J, MAYER, Ulrich

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Glucuronidation of 1′-Hydroxyestragole (1′-HE) by Human UDP-Glucuronosyltransferases UGT2B7 and UGT1A9 von Iyer, Lalitha V., Ho, Mark N., Shinn, Walter M., Bradford, Wallace W., Tanga, Mary J., Nath, Shirley S., Green, Carol E.

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Advances in breeding of dairy cattle von Pryce, Jennie

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Lead Optimization of 3-Carboxyl-4(1H)-Quinolones to Deliver Orally Bioavailable Antimalarials von Zhang, Yiqun, Clark, Julie A, Connelly, Michele C, Zhu, Fangyi, Min, Jaeki, Guiguemde, W. Armand, Pradhan, Anupam, Iyer, Lalitha, Furimsky, Anna, Gow, Jason, Parman, Toufan, El Mazouni, Farah, Phillips, Margaret A, Kyle, Dennis E, Mirsalis, Jon, Guy, R. Kiplin

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Phase I Clinical and Pharmacogenetic Study of Weekly TAS-103 in Patients With Advanced Cancer von EWESUEDO, Reginald B, LYER, Lalitha, DAS, Soma, KOENIG, Annette, MANI, Sridhar, VOGELZANG, Nicholas J, SCHILSKY, Richard L, BRENCKMAN, Wayne, RATAIN, Mark J

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Granulocyte Colony-Stimulating Factor (Neupogen®; Filgrastim) Accelerates Neutrophil Recovery in a Rodent Model of Sulfur Mustard-Induced Hematologic Toxicity von Beske, Phillip H, Harvilchuck, Jill A, Gibbs, Seth T, Green, Carol E, Iyer, Lalitha, O’Loughlin, Kathleen, Hu, Tom C-C, Nealy, Michael S, Platoff, Gennady E, Yeung, David T

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A parallel chiral–achiral liquid chromatographic method for the determination of the stereoisomers of ketamine and ketamine metabolites in the plasma and urine of patients with com... von Moaddel, Ruin, Venkata, Swarajya Lakshmi Vattem, Tanga, Mary J., Bupp, James E., Green, Carol E., Iyer, Lalitha, Furimsky, Anna, Goldberg, Michael E., Torjman, Marc C., Wainer, Irving W.

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Unraveling the Aflatoxin−FAPY Conundrum:  Structural Basis for Differential Replicative Processing of Isomeric Forms of the Formamidopyrimidine-Type DNA Adduct of Aflatoxin B 1 von Brown, Kyle L., Deng, James Z., Iyer, Rajkumar S., Iyer, Lalitha G., Voehler, Markus W., Stone, Michael P., Harris, Constance M., Harris, Thomas M.

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