Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis von Wang, Ying-Hua, Israelsen, William J, Lee, Dongjun, Yu, Vionnie W C, Jeanson, Nathaniel T, Clish, Clary B, Cantley, Lewis C, Vander Heiden, Matthew G, Scadden, David T

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Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages von Palsson-McDermott, Eva M., Curtis, Anne M., Goel, Gautam, Lauterbach, Mario A.R., Sheedy, Frederick J., Gleeson, Laura E., van den Bosch, Mirjam W.M., Quinn, Susan R., Domingo-Fernandez, Raquel, Johnston, Daniel G.W., Jiang, Jian-kang, Israelsen, William J., Keane, Joseph, Thomas, Craig, Clish, Clary, Vander Heiden, Matthew, Xavier, Ramnik J., O’Neill, Luke A.J.

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Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction von Qi, Weier, Keenan, Hillary A, Li, Qian, Ishikado, Atsushi, Kannt, Aimo, Sadowski, Thorsten, Yorek, Mark A, Wu, I-Hsien, Lockhart, Samuel, Coppey, Lawrence J, Pfenninger, Anja, Liew, Chong Wee, Qiang, Guifen, Burkart, Alison M, Hastings, Stephanie, Pober, David, Cahill, Christopher, Niewczas, Monika A, Israelsen, William J, Tinsley, Liane, Stillman, Isaac E, Amenta, Peter S, Feener, Edward P, Vander Heiden, Matthew G, Stanton, Robert C, King, George L

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Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma von Dayton, Talya L, Gocheva, Vasilena, Miller, Kathryn M, Israelsen, William J, Bhutkar, Arjun, Clish, Clary B, Davidson, Shawn M, Luengo, Alba, Bronson, Roderick T, Jacks, Tyler, Vander Heiden, Matthew G

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Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation von Lunt, Sophia Y., Muralidhar, Vinayak, Hosios, Aaron M., Israelsen, William J., Gui, Dan Y., Newhouse, Lauren, Ogrodzinski, Martin, Hecht, Vivian, Xu, Kali, Acevedo, Paula N. Marín, Hollern, Daniel P., Bellinger, Gary, Dayton, Talya L., Christen, Stefan, Elia, Ilaria, Dinh, Anh T., Stephanopoulos, Gregory, Manalis, Scott R., Yaffe, Michael B., Andrechek, Eran R., Fendt, Sarah-Maria, Vander Heiden, Matthew G.

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Breeding and hibernation of captive meadow jumping mice (Zapus hudsonius) von Brem, Ethan A, McNulty, Alyssa D, Israelsen, William J

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Pyruvate kinase: Function, regulation and role in cancer von Israelsen, William J., Vander Heiden, Matthew G.

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Nesting box imager: Contact-free, real-time measurement of activity, surface body temperature, and respiratory rate applied to hibernating mouse models von Kallmyer, Nathaniel E, Shin, Han Jong, Brem, Ethan A, Israelsen, William J, Reuel, Nigel F

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Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma von Davidson, Shawn M, Schmidt, Daniel R, Heyman, Julia E, O'Brien, James P, Liu, Amy C, Israelsen, William J, Dayton, Talya L, Sehgal, Raghav, Bronson, Roderick T, Freinkman, Elizaveta, Mak, Howard H, Fanelli, Giuseppe Nicolò, Malstrom, Scott, Bellinger, Gary, Carracedo, Arkaitz, Pandolfi, Pier Paolo, Courtney, Kevin D, Jha, Abhishek, DePinho, Ronald A, Horner, James W, Thomas, Craig J, Cantley, Lewis C, Loda, Massimo, Vander Heiden, Matthew G

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Fibroblasts as an experimental model system for the study of comparative physiology von Madelaire, Carla B., Klink, Amy C., Israelsen, William J., Hindle, Allyson G.

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PKM2 is not required for colon cancer initiated by APC loss von Lau, Allison N, Israelsen, William J, Roper, Jatin, Sinnamon, Mark J, Georgeon, Larissa, Dayton, Talya L, Hillis, Alissandra L, Yilmaz, Omer H, Di Vizio, Dolores, Hung, Kenneth E, Vander Heiden, Matthew G

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PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells von Israelsen, William J., Dayton, Talya L., Davidson, Shawn M., Fiske, Brian P., Hosios, Aaron M., Bellinger, Gary, Li, Jie, Yu, Yimin, Sasaki, Mika, Horner, James W., Burga, Laura N., Xie, Jianxin, Jurczak, Michael J., DePinho, Ronald A., Clish, Clary B., Jacks, Tyler, Kibbey, Richard G., Wulf, Gerburg M., Di Vizio, Dolores, Mills, Gordon B., Cantley, Lewis C., Vander Heiden, Matthew G.

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Cancer‐associated mutations in human pyruvate kinase M2 impair enzyme activity von Liu, Vivian M., Howell, Andrea J., Hosios, Aaron M., Li, Zhaoqi, Israelsen, William J., Vander Heiden, Matthew G.

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Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages von Palsson-McDermott, Eva M., Curtis, Anne M., Goel, Gautam, Lauterbach, Mario A.R., Sheedy, Frederick J., Gleeson, Laura E., van den Bosch, Mirjam W.M., Quinn, Susan R., Domingo-Fernandez, Raquel, Johnston, Daniel G.W., Jiang, Jian-kang, Israelsen, William J., Keane, Joseph, Thomas, Craig, Clish, Clary, Vander Heiden, Matthew, Xavier, Ramnik J., O’Neill, Luke A.J.

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Courtship Behavior of the Meadow Jumping Mouse (Zapus hudsonius) von Brem, Ethan A., Israelsen, William J.

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ATP Consumption Promotes Cancer Metabolism von Israelsen, William J., Vander Heiden, Matthew G.

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Cutaneous Dermatophilosis in a Meadow Jumping Mouse (Zapus hudsonius) von Caron, Tyler J, Artim, Stephen C, Israelsen, William J, Holcombe, Hilda R, Fox, James G, Bakthavatchalu, Vasudevan

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2-Oxo- N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase von Walsh, Martin J., Brimacombe, Kyle R., Veith, Henrike, Bougie, James M., Daniel, Thomas, Leister, William, Cantley, Lewis C., Israelsen, William J., Vander Heiden, Matthew G., Shen, Min, Auld, Douglas S., Thomas, Craig J., Boxer, Matthew B.

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Hibernation: Insights from Comparative Genomics of Zapus Species von Israelsen, William J., McNulty, Alyssa D., Cong, Qian

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Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis von Anastasiou, Dimitrios, Yu, Yimin, Israelsen, William J, Jiang, Jian-Kang, Boxer, Matthew B, Hong, Bum Soo, Tempel, Wolfram, Dimov, Svetoslav, Shen, Min, Jha, Abhishek, Yang, Hua, Mattaini, Katherine R, Metallo, Christian M, Fiske, Brian P, Courtney, Kevin D, Malstrom, Scott, Khan, Tahsin M, Kung, Charles, Skoumbourdis, Amanda P, Veith, Henrike, Southall, Noel, Walsh, Martin J, Brimacombe, Kyle R, Leister, William, Lunt, Sophia Y, Johnson, Zachary R, Yen, Katharine E, Kunii, Kaiko, Davidson, Shawn M, Christofk, Heather R, Austin, Christopher P, Inglese, James, Harris, Marian H, Asara, John M, Stephanopoulos, Gregory, Salituro, Francesco G, Jin, Shengfang, Dang, Lenny, Auld, Douglas S, Park, Hee-Won, Cantley, Lewis C, Thomas, Craig J, Vander Heiden, Matthew G

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