Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality von Nakanishi, Tomoko, Pigazzini, Sara, Degenhardt, Frauke, Cordioli, Mattia, Butler-Laporte, Guillaume, Maya-Miles, Douglas, Bujanda, Luis, Bouysran, Youssef, Niemi, Mari E.K., Palom, Adriana, Ellinghaus, David, Khan, Atlas, Martínez-Bueno, Manuel, Rolker, Selina, Amitrano, Sara, Roade Tato, Luisa, Fava, Francesca, Spinner, Christoph D., Prati, Daniele, Bernardo, David, Garcia, Federico, Darcis, Gilles, Fernández-Cadenas, Israel, Holter, Jan Cato, Banales, Jesus M., Frithiof, Robert, Kiryluk, Krzysztof, Duga, Stefano, Asselta, Rosanna, Pereira, Alexandre C., Romero-Gómez, Manuel, Nafría-Jiménez, Beatriz, Hov, Johannes R., Migeotte, Isabelle, Renieri, Alessandra, Planas, Anna M., Ludwig, Kerstin U., Buti, Maria, Rahmouni, Souad, Alarcón-Riquelme, Marta E., Schulte, Eva C., Franke, Andre, Karlsen, Tom H., Valenti, Luca, Zeberg, Hugo, Richards, J. Brent, Ganna, Andrea

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Genetically Elevated LDL Associates with Lower Risk of Intracerebral Hemorrhage von Falcone, Guido J., Kirsch, Elayna, Acosta, Julian N., Noche, Rommell B., Leasure, Audrey, Marini, Sandro, Chung, Jaeyoon, Selim, Magdy, Meschia, James F., Brown, Devin L., Worrall, Bradford B., Tirschwell, David L., Jagiella, Jeremiasz M., Schmidt, Helena, Jimenez‐Conde, Jordi, Fernandez‐Cadenas, Israel, Lindgren, Arne, Slowik, Agnieszka, Gill, Dipender, Holmes, Michael, Phuah, Chia‐Ling, Petersen, Nils H., Matouk, MD, Charles N., Gunel, Murat, Sansing, Lauren, Bennett, Derrick, Chen, Zhengming, Sun, Luan L., Clarke, Robert, Walters, Robin G., Gill, Thomas M., Biffi, Alessandro, Kathiresan, Sekar, Langefeld, Carl D., Woo, Daniel, Rosand, Jonathan, Sheth, Kevin N., Anderson, Christopher D.

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Biological age is better than chronological as predictor of 3-month outcome in ischemic stroke von Soriano-Tárraga, Carolina, Mola-Caminal, Marina, Giralt-Steinhauer, Eva, Ois, Angel, Rodríguez-Campello, Ana, Cuadrado-Godia, Elisa, Gómez-González, Alejandra, Vivanco-Hidalgo, Rosa M, Fernández-Cadenas, Israel, Cullell, Natalia, Roquer, Jaume, Jiménez-Conde, Jordi

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Variants at APOE influence risk of deep and lobar intracerebral hemorrhage von Biffi, Alessandro, Sonni, Akshata, Anderson, Christopher D., Kissela, Brett, Jagiella, Jeremiasz M., Schmidt, Helena, Jimenez-Conde, Jordi, Hansen, Björn M., Fernandez-Cadenas, Israel, Cortellini, Lynelle, Ayres, Alison, Schwab, Kristin, Juchniewicz, Karol, Urbanik, Andrzej, Rost, Natalia S., Viswanathan, Anand, Seifert-Held, Thomas, Stoegerer, Eva-Maria, Tomás, Marta, Rabionet, Raquel, Estivill, Xavier, Brown, Devin L., Silliman, Scott L., Selim, Magdy, Worrall, Bradford B., Meschia, James F., Montaner, Joan, Lindgren, Arne, Roquer, Jaume, Schmidt, Reinhold, Greenberg, Steven M., Slowik, Agnieszka, Broderick, Joseph P., Woo, Daniel, Rosand, Jonathan

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Tissue plasminogen activator (t-PA) promotes neutrophil degranulation and MMP-9 release von Cuadrado, Eloy, Ortega, Laura, Hernández‐Guillamon, Mar, Penalba, Anna, Fernández‐Cadenas, Israel, Rosell, Anna, Montaner, Joan

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Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study von Soriano-Tárraga, Carolina, Lazcano, Uxue, Giralt-Steinhauer, Eva, Avellaneda-Gómez, Carla, Ois, Ángel, Rodríguez-Campello, Ana, Cuadrado-Godia, Elisa, Gómez-González, Alejandra, Fernández-Sanlés, Alba, Elosua, Roberto, Fernández-Cadenas, Israel, Cullell, Natalia, Montaner, Joan, Moran, Sebastian, Esteller, Manel, Jiménez-Conde, Jordi, Roquer, Jaume

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DNA methylation analyses identify an intronic ZDHHC6 locus associated with time to recurrent stroke in the Vitamin Intervention for Stroke Prevention (VISP) clinical trial von Davis Armstrong, Nicole M, Chen, Wei-Min, Hsu, Fang-Chi, Brewer, Michael S, Cullell, Natalia, Fernández-Cadenas, Israel, Williams, Stephen R, Sale, Michèle M, Worrall, Bradford B, Keene, Keith L

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Leveraging Genetic Data to Elucidate the Relationship Between COVID-19 and Ischemic Stroke von Zuber, Verena, Cameron, Alan, Myserlis, Evangelos P, Bottolo, Leonardo, Fernandez-Cadenas, Israel, Burgess, Stephen, Anderson, Christopher D, Dawson, Jesse, Gill, Dipender

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Genetic Architecture of Ischaemic Strokes after COVID-19 Shows Similarities with Large Vessel Strokes von Llucià-Carol, Laia, Muiño, Elena, Cullell, Natalia, Cárcel-Márquez, Jara, Lledós, Miquel, Gallego-Fabrega, Cristina, Martin-Campos, Jesús, Martí-Fàbregas, Joan, Aguilera-Simón, Ana, Planas, Anna M., DeDiego, Marta L., de Felipe Mimbrera, Alicia, Masjuan, Jaime, García-Madrona, Sebastián, Segura, Tomás, González-Villar, Esther, Serrano-Heras, Gemma, Domínguez Mayoral, Ana, Menéndez-Valladares, Paloma, Montaner, Joan, Migeotte, Isabelle, Rahmouni, Souad, Darcis, Gilles, Bernardo, David, Rojo, Silvia, Schulte, Eva C., Protzer, Ulrike, Fricke, Lisa, Winter, Christof, Niemi, Mari E. K., Cordioli, Mattia, Delgado, Pilar, Fernández-Cadenas, Israel

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Limb-girdle muscular dystrophy 1F is caused by a microdeletion in the transportin 3 gene von MELIA, Maria J, KUBOTA, Akatsuki, GARCIA-ARUMI, Elena, ANDREU, Antoni L, NAVARRO, Carmen, HIRANO, Michio, MARTI, Ramon, ORTOLANO, Saida, VILCHEZ, Juan J, GAMEZ, Josep, TANJ I, Kurenai, BONILLA, Eduardo, PALENZUELA, Lluís, FERNANDEZ-CADENAS, Israel, PRISTOUPILOVA, Anna

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Genome-wide transcriptome study in skin biopsies reveals an association of E2F4 with cadasil and cognitive impairment von Muiño, Elena, Maisterra, Olga, Jiménez-Balado, Joan, Cullell, Natalia, Carrera, Caty, Torres-Aguila, Nuria P., Cárcel-Márquez, Jara, Gallego-Fabrega, Cristina, Lledós, Miquel, González-Sánchez, Jonathan, Olmos-Alpiste, Ferran, Espejo, Eva, March, Álvaro, Pujol, Ramón, Rodríguez-Campello, Ana, Romeral, Gemma, Krupinski, Jurek, Martí-Fàbregas, Joan, Montaner, Joan, Roquer, Jaume, Fernández-Cadenas, Israel

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Global DNA methylation of ischemic stroke subtypes von Soriano-Tárraga, Carolina, Jiménez-Conde, Jordi, Giralt-Steinhauer, Eva, Mola, Marina, Ois, Angel, Rodríguez-Campello, Ana, Cuadrado-Godia, Elisa, Fernández-Cadenas, Israel, Carrera, Caty, Montaner, Joan, Elosua, Roberto, Roquer, Jaume

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Brain perihematoma genomic profile following spontaneous human intracerebral hemorrhage von Rosell, Anna, Vilalta, Anna, García-Berrocoso, Teresa, Fernández-Cadenas, Israel, Domingues-Montanari, Sophie, Cuadrado, Eloy, Delgado, Pilar, Ribó, Marc, Martínez-Sáez, Elena, Ortega-Aznar, Arantxa, Montaner, Joan

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Using Human Genetics to Understand Mechanisms in Ischemic Stroke Outcome: From Early Brain Injury to Long-Term Recovery von Lee, Jin-Moo, Fernandez-Cadenas, Israel, Lindgren, Arne G.

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DNA methylation and stroke prognosis: an epigenome-wide association study von Jiménez-Balado, Joan, Fernández-Pérez, Isabel, Gallego-Fábrega, Cristina, Lazcano, Uxue, Soriano-Tárraga, Carolina, Vallverdú-Prats, Marta, Mola-Caminal, Marina, Rey-Álvarez, Lucía, Macias-Gómez, Adrià, Suárez-Pérez, Antoni, Giralt-Steinhauer, Eva, Rodríguez-Campello, Ana, Cuadrado-Godia, Elisa, Ois, Ángel, Esteller, Manel, Roquer, Jaume, Fernández-Cadenas, Israel, Jiménez-Conde, Jordi

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Contribution of “Omic” Studies to the Understanding of Cadasil. A Systematic Review von Muiño, Elena, Fernández-Cadenas, Israel, Arboix, Adrià

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Progression of Symptomatic Intracranial Large Artery Atherosclerosis Is Associated With a Proinflammatory State and Impaired Fibrinolysis von ARENILLAS, Juan F, ALVAREZ-SABIN, José, MONTANER, Joan, MOLINA, Carlos A, CHACON, Pilar, FERNANDEZ-CADENAS, Israel, RIBO, Marc, DELGADO, Pilar, RUBIERA, Marta, PENALBA, Anna, ROVIRA, Alex

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Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies von Traylor, Matthew, Persyn, Elodie, Tomppo, Liisa, Klasson, Sofia, Abedi, Vida, Bakker, Mark K, Torres, Nuria, Li, Linxin, Bell, Steven, Rutten-Jacobs, Loes, Tozer, Daniel J, Griessenauer, Christoph J, Zhang, Yanfei, Pedersen, Annie, Sharma, Pankaj, Jimenez-Conde, Jordi, Rundek, Tatjana, Grewal, Raji P, Lindgren, Arne, Meschia, James F, Salomaa, Veikko, Havulinna, Aki, Kourkoulis, Christina, Crawford, Katherine, Marini, Sandro, Mitchell, Braxton D, Kittner, Steven J, Rosand, Jonathan, Dichgans, Martin, Jern, Christina, Strbian, Daniel, Fernandez-Cadenas, Israel, Zand, Ramin, Ruigrok, Ynte, Rost, Natalia, Lemmens, Robin, Rothwell, Peter M, Anderson, Christopher D, Wardlaw, Joanna, Lewis, Cathryn M, Markus, Hugh S

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Systematic Review of Cysteine-Sparing NOTCH3 Missense Mutations in Patients with Clinical Suspicion of CADASIL von Muiño, Elena, Gallego-Fabrega, Cristina, Cullell, Natalia, Carrera, Caty, Torres, Nuria, Krupinski, Jurek, Roquer, Jaume, Montaner, Joan, Fernández-Cadenas, Israel

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Role of PATJ in stroke prognosis by modulating endothelial to mesenchymal transition through the Hippo/Notch/PI3K axis von Medina-Dols, Aina, Cañellas, Guillem, Capó, Toni, Solé, Montse, Mola-Caminal, Marina, Cullell, Natalia, Jaume, Marina, Nadal-Salas, Laura, Llinàs, Jaume, Gómez, Lluis, Tur, Silvia, Jiménez, Carmen, Díaz, Rosa M., Carrera, Caty, Muiño, Elena, Gallego-Fabrega, Cristina, Soriano-Tárraga, Carolina, Ruiz-Guerra, Laura, Pol-Fuster, Josep, Asensio, Víctor, Muncunill, Josep, Fleischer, Aarne, Iglesias, Amanda, Giralt-Steinhauer, Eva, Lazcano, Uxue, Fernández-Pérez, Isabel, Jiménez-Balado, Joan, Gabriel-Salazar, Marina, Garcia-Gabilondo, Miguel, Lei, Ting, Torres-Aguila, Nuria-Paz, Cárcel-Márquez, Jara, Lladó, Jerònia, Olmos, Gabriel, Rosell, Anna, Montaner, Joan, Planas, Anna M., Rabionet, Raquel, Hernández-Guillamon, Mar, Jiménez-Conde, Jordi, Fernández-Cadenas, Israel, Vives-Bauzá, Cristòfol

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