Proteogenomics refines the molecular classification of chronic lymphocytic leukemia von Herbst, Sophie A., Vesterlund, Mattias, Helmboldt, Alexander J., Jafari, Rozbeh, Siavelis, Ioannis, Stahl, Matthias, Schitter, Eva C., Liebers, Nora, Brinkmann, Berit J., Czernilofsky, Felix, Roider, Tobias, Bruch, Peter-Martin, Iskar, Murat, Kittai, Adam, Huang, Ying, Lu, Junyan, Richter, Sarah, Mermelekas, Georgios, Umer, Husen Muhammad, Knoll, Mareike, Kolb, Carolin, Lenze, Angela, Cao, Xiaofang, Österholm, Cecilia, Wahnschaffe, Linus, Herling, Carmen, Scheinost, Sebastian, Ganzinger, Matthias, Mansouri, Larry, Kriegsmann, Katharina, Kriegsmann, Mark, Anders, Simon, Zapatka, Marc, Del Poeta, Giovanni, Zucchetto, Antonella, Bomben, Riccardo, Gattei, Valter, Dreger, Peter, Woyach, Jennifer, Herling, Marco, Müller-Tidow, Carsten, Rosenquist, Richard, Stilgenbauer, Stephan, Zenz, Thorsten, Huber, Wolfgang, Tausch, Eugen, Lehtiö, Janne, Dietrich, Sascha

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P04.04 Optimizing dasatinib for glioblastoma treatment von Alhalabi, O, Göttmann, M, Gold, M, Fletcher, M, Hielscher, T, Iskar, M, Kessler, T, Wittmann, E, Schlue, S, Rahman, S, Hai, L, Hansen-Palmus, L, Puccio, L, Nakano, I, Herold-Mende, C, Baumgartner, U, Day, B, Wick, W, Sahm, F, Fraenkel, E, Phillips, E, Goidts, V

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Maintenance of EGFR plasma membrane levels involves cargo-specific COPII components of the early secretory pathway machinery von Scharaw, S., Iskar, M., Ori, A., Boncompain, G., Laketa, V., Poser, I., Lundberg, Emma, Perez, F., Beck, M., Bork, P., Pepperkok, R.

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Author Correction: The landscape of viral associations in human cancers von Zapatka, M, Borozan, I, Brewer, DS, Iskar, M, Grundhoff, A, Alawi, M, Desai, N, Sültmann, H, Moch, H, Cooper, CS, Eils, R, Ferretti, V, Kleinheinz, K, Lichter, P, Nakagawa, H, Ojesina, AI, Pedamallu, CS, Schlesner, M, Su, X, Aaltonen, LA, Abascal, F, Abeshouse, A, Aburatani, H, Adams, DJ, Agrawal, N, Ahn, KS, Ahn, SM, Aikata, H, Akbani, R, Akdemir, KC, Al-Ahmadie, H, Al-Sedairy, ST, Al-Shahrour, F, Albert, M, Aldape, K, Alexandrov, LB, Ally, A, Alsop, K, Alvarez, EG, Amary, F, Amin, SB, Aminou, B, Ammerpohl, O, Anderson, MJ, Ang, Y, Antonello, D, Anur, P, Aparicio, S, Appelbaum, EL, Arai, Y, Aretz, A, Arihiro, K, Ariizumi, SI, Armenia, J, Arnould, L, Asa, S, Assenov, Y, Atwal, G, Aukema, S, Auman, JT, Aure, MRR, Awadalla, P, Aymerich, M, Bader, GD, Baez-Ortega, A, Bailey, MH, Bailey, PJ, Balasundaram, M, Balu, S, Bandopadhayay, P, Banks, RE, Barbi, S, Barbour, AP, Barenboim, J, Barnholtz-Sloan, J, Barr, H, Barrera, E, Bartlett, J, Bartolome, J, Bassi, C, Bathe, OF, Baumhoer, D, Bavi, P, Baylin, SB, Bazant, W, Beardsmore, D, Beck, TA, Behjati, S

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CART-a chemical annotation retrieval toolkit von Deghou, S., Zeller, G., Iskar, M., Driessen, M., Castillo, M., Noort, V. van, Bork, P.

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The landscape of viral associations in human cancers von Zapatka, M, Borozan, I, Brewer, DS, Iskar, M, Grundhoff, A, Alawi, M, Desai, N, Sültmann, H, Moch, H, Cooper, CS, Eils, R, Ferretti, V, Lichter, P, Kleinheinz, K, Nakagawa, H, Ojesina, AI, Pedamallu, CS, Schlesner, M, Su, X

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Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration von Chun, Hye-Jung E., Johann, Pascal D., Milne, Katy, Zapatka, Marc, Buellesbach, Annette, Ishaque, Naveed, Iskar, Murat, Erkek, Serap, Wei, Lisa, Tessier-Cloutier, Basile, Lever, Jake, Titmuss, Emma, Topham, James T., Bowlby, Reanne, Chuah, Eric, Mungall, Karen L., Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Taylor, Michael D., Gerhard, Daniela S., Jones, Steven J.M., Korshunov, Andrey, Gessler, Manfred, Kerl, Kornelius, Hasselblatt, Martin, Frühwald, Michael C., Perlman, Elizabeth J., Nelson, Brad H., Pfister, Stefan M., Marra, Marco A., Kool, Marcel

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Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations von Pfaff, Elke, Aichmüller, Christian, Sill, Martin, Stichel, Damian, Snuderl, Matija, Karajannis, Matthias A., Schuhmann, Martin U., Schittenhelm, Jens, Hasselblatt, Martin, Thomas, Christian, Korshunov, Andrey, Rhizova, Marina, Wittmann, Andrea, Kaufhold, Anna, Iskar, Murat, Ketteler, Petra, Lohmann, Dietmar, Orr, Brent A., Ellison, David W., von Hoff, Katja, Mynarek, Martin, Rutkowski, Stefan, Sahm, Felix, von Deimling, Andreas, Lichter, Peter, Kool, Marcel, Zapatka, Marc, Pfister, Stefan M., Jones, David T. W.

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Author Correction: Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCF von Iurlaro, Mario, Masoni, Francesca, Flyamer, Ilya M., Wirbelauer, Christiane, Iskar, Murat, Burger, Lukas, Giorgetti, Luca, Schübeler, Dirk

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The landscape of viral associations in human cancers von Zapatka, Marc, Borozan, Ivan, Brewer, Daniel S., Iskar, Murat, Grundhoff, Adam, Alawi, Malik, Desai, Nikita, Sültmann, Holger, Moch, Holger, Cooper, Colin S., Eils, Roland, Ferretti, Vincent, Lichter, Peter

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Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks von Mallm, Jan‐Philipp, Iskar, Murat, Ishaque, Naveed, Klett, Lara C, Kugler, Sabrina J, Muino, Jose M, Teif, Vladimir B, Poos, Alexandra M, Großmann, Sebastian, Erdel, Fabian, Tavernari, Daniele, Koser, Sandra D, Schumacher, Sabrina, Brors, Benedikt, König, Rainer, Remondini, Daniel, Vingron, Martin, Stilgenbauer, Stephan, Lichter, Peter, Zapatka, Marc, Mertens, Daniel, Rippe, Karsten

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Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCF von Iurlaro, Mario, Masoni, Francesca, Flyamer, Ilya M., Wirbelauer, Christiane, Iskar, Murat, Burger, Lukas, Giorgetti, Luca, Schübeler, Dirk

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Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity von Hanna, Bola S., Llaó-Cid, Laura, Iskar, Murat, Roessner, Philipp M., Klett, Lara C., Wong, John K.L., Paul, Yashna, Ioannou, Nikolaos, Öztürk, Selcen, Mack, Norman, Kalter, Verena, Colomer, Dolors, Campo, Elías, Bloehdorn, Johannes, Stilgenbauer, Stephan, Dietrich, Sascha, Schmidt, Manfred, Gabriel, Richard, Rippe, Karsten, Feuerer, Markus, Ramsay, Alan G., Lichter, Peter, Zapatka, Marc, Seiffert, Martina

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Immune Suppression in CLL Is Mediated By the L-Amino Acid Oxidase IL4I1, a Reason for the Treatment Failure of IDO1 Inhibitors von Öztürk, Selcen, Iskar, Murat, Sunbul, Murat, Rößner, Philipp M, Zapatka, Marc, Seiffert, Martina

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DECIPHER pooled shRNA library screen identifies PP2A and FGFR signaling as potential therapeutic targets for diffuse intrinsic pontine gliomas von Schramm, Kathrin, Iskar, Murat, Statz, Britta, Jäger, Natalie, Haag, Daniel, Słabicki, Mikołaj, Pfister, Stefan M, Zapatka, Marc, Gronych, Jan, Jones, David T W, Lichter, Peter

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A synergistic interaction between HDAC‐ and PARP inhibitors in childhood tumors with chromothripsis von Khalid, Umar, Simovic, Milena, Hammann, Linda A., Iskar, Murat, Wong, John K. L., Kumar, Rithu, Jugold, Manfred, Sill, Martin, Bolkestein, Michiel, Kolb, Thorsten, Hergt, Michaela, Devens, Frauke, Ecker, Jonas, Kool, Marcel, Milde, Till, Westermann, Frank, Benner, Axel, Lewis, Joe, Dietrich, Sascha, Pfister, Stefan M., Lichter, Peter, Zapatka, Marc, Ernst, Aurélie

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Integration of transcriptomics, proteomics and loss-of-function screening reveals WEE1 as a target for combination with dasatinib against proneural glioblastoma von Alhalabi, Obada T., Göttmann, Mona, Gold, Maxwell P., Schlue, Silja, Hielscher, Thomas, Iskar, Murat, Kessler, Tobias, Hai, Ling, Lokumcu, Tolga, Cousins, Clara C., Herold-Mende, Christel, Heßling, Bernd, Horschitz, Sandra, Jabali, Ammar, Koch, Philipp, Baumgartner, Ulrich, Day, Bryan W., Wick, Wolfgang, Sahm, Felix, Krieg, Sandro M., Fraenkel, Ernest, Phillips, Emma, Goidts, Violaine

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Pilocytic astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response von Aichmüller, Christian F, Iskar, Murat, Jones, David T W, Korshunov, Andrey, Radlwimmer, Bernhard, Kool, Marcel, Ernst, Aurelie, Pfister, Stefan M, Lichter, Peter, Zapatka, Marc

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ATRT-09. INTEGRATIVE ANALYSES OF GENE REGULATORY LANDSCAPES REVEAL RHABDOID TUMOR SUBGROUPS WITH POSSIBLE IMMUNE MODULATION THROUGH EPIGENETIC DYSREGULATION von Johann, Pascal, Chun, Hye-Jung, Erkek, Serap, Iskar, Murat, Perlman, Elizabeth, Hasselblatt, Martin, Pfister, Stefan M, Marra, Marco, Kool, Marcel

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Resilience of forest village communities in the implementation of the community forest policy von Tjoa, M, Iskar, Latukau, S H

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