Efficacy and safety of different doses and retreatment of rituximab: a randomised, placebo-controlled trial in patients who are biological naïve with active rheumatoid arthritis an... von Emery, P, Deodhar, A, Rigby, W F, Isaacs, J D, Combe, B, Racewicz, A J, Latinis, K, Abud-Mendoza, C, Szczepański, L J, Roschmann, R A, Chen, A, Armstrong, G K, Douglass, W, Tyrrell, H

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Therapeutic T-cell manipulation in rheumatoid arthritis: past, present and future von Isaacs, J. D.

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TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis von Cole, M., Yap, C., Buckley, C., Ng, W. F., McInnes, I., Filer, A., Siebert, S., Pratt, A., Isaacs, J. D., Stocken, D. D.

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The role of the cellular prion protein in the immune system von Isaacs, J. D., Jackson, G. S., Altmann, D. M.

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Prospective study of anti‐tumour necrosis factor receptor superfamily 1B fusion protein, and case study of anti‐tumour necrosis factor receptor superfamily 1A fusion protein, in tu... von Drewe, E., McDermott, E. M., Powell, P. T., Isaacs, J. D., Powell, R. J.

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Tolerogenic dendritic cell therapy for rheumatoid arthritis: where are we now? von Hilkens, C. M. U., Isaacs, J. D.

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Brain pseudotumour secondary to Behçet's disease von Mousa, A E, Okasha, M, Isaacs, J D, Price, D A, Bhatnagar, P, Joshi, A, Surash, S

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Determination of thymic function directly from peripheral blood: A validated modification to an established method von Lorenzi, A.R., Patterson, A.M., Pratt, A., Jefferson, M., Chapman, C.E., Ponchel, F., Isaacs, J.D.

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Biosimilars in immune‐mediated inflammatory diseases: initial lessons from the first approved biosimilar anti‐tumour necrosis factor monoclonal antibody von Isaacs, J. D., Cutolo, M., Keystone, E. C., Park, W., Braun, J.

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Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis von Reynolds, G, Gibbon, J R, Pratt, A G, Wood, M J, Coady, D, Raftery, G, Lorenzi, A R, Gray, A, Filer, A, Buckley, C D, Haniffa, M A, Isaacs, J D, Hilkens, C M U

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Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4+ T cells partly via transforming growth factor‐β1 von Anderson, A. E., Swan, D. J., Wong, O. Y., Buck, M., Eltherington, O., Harry, R. A., Patterson, A. M., Pratt, A. G., Reynolds, G., Doran, J.‐P., Kirby, J. A., Isaacs, J. D., Hilkens, C. M. U.

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Outcome of intensive immunosuppression and autologous stem cell transplantation in patients with severe rheumatoid arthritis is associated with the composition of synovial T cell i... von Verburg, R J, Flierman, R, Sont, J K, Ponchel, F, van Dreunen, L, Levarht, E W, Welling, M M, Toes, R E M, Isaacs, J D, van Laar, J M

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Bilateral facial nerve palsy associated with Epstein–Barr virus infection von Coddington, C T, Isaacs, J D, Siddiqui, A Q, Andrews, T C

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Thymic function in juvenile idiopathic arthritis von Lorenzi, A R, Morgan, T A, Anderson, A, Catterall, J, Patterson, A M, Foster, H E, Isaacs, J D

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Abnormal T cell differentiation persists in patients with rheumatoid arthritis in clinical remission and predicts relapse von Burgoyne, C H, Field, S L, Brown, A K, Hensor, E M, English, A, Bingham, S L, Verburg, R, Fearon, U, Lawson, C A, Hamlin, P J, Straszynski, L, Veale, D, Conaghan, P, Hull, M A, van Laar, J M, Tennant, A, Emery, P, Isaacs, J D, Ponchel, F

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Atacicept, a novel B cell-targeting biological therapy for the treatment of rheumatoid arthritis von Bracewell, C, Isaacs, JD, Emery, P, Ng, WF

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Activated polyamidoamine dendrimers, a non-viral vector for gene transfer to the corneal endothelium von HUDDE, T, RAYNER, S. A, COMER, R. M, WEBER, M, ISAACS, J. D, WALDMANN, H, LARKIN, D. F. P, GEORGE, A. J. T

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Humanised monoclonal antibody therapy for rheumatoid arthritis von Isaacs, J.D., Hale, G., Cobbold, S.P., Waldmann, H., Watts, R.A., Hazleman, B.L., Keogan, M.T.

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From bench to bedside: discovering rules for antibody design, and improving serotherapy with monoclonal antibodies von ISAACS, J. D

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Long-term remission of intractable systemic vasculitis with monoclonal antibody therapy von Lockwood, C.M., Thiru, S., Isaacs, J.D., Hale, G., Waldmann, H.

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