A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes von Bazak, Lily, Haviv, Ami, Barak, Michal, Jacob-Hirsch, Jasmine, Deng, Patricia, Zhang, Rui, Isaacs, Farren J, Rechavi, Gideon, Li, Jin Billy, Eisenberg, Eli, Levanon, Erez Y

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Engineering an allosteric transcription factor to respond to new ligands von Taylor, Noah D, Garruss, Alexander S, Moretti, Rocco, Chan, Sum, Arbing, Mark A, Cascio, Duilio, Rogers, Jameson K, Isaacs, Farren J, Kosuri, Sriram, Baker, David, Fields, Stanley, Church, George M, Raman, Srivatsan

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Genomically Recoded Organisms Expand Biological Functions von Lajoie, Marc J., Rovner, Alexis J., Goodman, Daniel B., Aerni, Hans-Rudolf, Haimovich, Adrian D., Kuznetsov, Gleb, Mercer, Jaron A., Wang, Harris H., Carr, Peter A., Mosberg, Joshua A., Rohland, Nadin, Schultz, Peter G., Jacobson, Joseph M., Rinehart, Jesse, Church, George M., Isaacs, Farren J.

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Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids von Martin, Rey W., Des Soye, Benjamin J., Kwon, Yong-Chan, Kay, Jennifer, Davis, Roderick G., Thomas, Paul M., Majewska, Natalia I., Chen, Cindy X., Marcum, Ryan D., Weiss, Mary Grace, Stoddart, Ashleigh E., Amiram, Miriam, Ranji Charna, Arnaz K., Patel, Jaymin R., Isaacs, Farren J., Kelleher, Neil L., Hong, Seok Hoon, Jewett, Michael C.

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Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids von Amiram, Miriam, Haimovich, Adrian D, Fan, Chenguang, Wang, Yane-Shih, Aerni, Hans-Rudolf, Ntai, Ioanna, Moonan, Daniel W, Ma, Natalie J, Rovner, Alexis J, Hong, Seok Hoon, Kelleher, Neil L, Goodman, Andrew L, Jewett, Michael C, Söll, Dieter, Rinehart, Jesse, Isaacs, Farren J

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Targeted editing and evolution of engineered ribosomes in vivo by filtered editing von Radford, Felix, Elliott, Shane D., Schepartz, Alanna, Isaacs, Farren J.

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Photo‐Crosslinkable Unnatural Amino Acids Enable Facile Synthesis of Thermoresponsive Nano‐ to Microgels of Intrinsically Disordered Polypeptides von Costa, Simone A., Simon, Joseph R., Amiram, Miriam, Tang, Lei, Zauscher, Stefan, Brustad, Eric M., Isaacs, Farren J., Chilkoti, Ashutosh

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Enhanced eMAGE applied to identify genetic factors of nuclear hormone receptor dysfunction via combinatorial gene editing von Ciaccia, Peter N., Liang, Zhuobin, Schweitzer, Anabel Y., Metzner, Eli, Isaacs, Farren J.

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The Genome Project–Write von Boeke, Jef D., Church, George, Hessel, Andrew, Kelley, Nancy J., Arkin, Adam, Cai, Yizhi, Carlson, Rob, Chakravarti, Aravinda, Cornish, Virginia W., Holt, Liam, Isaacs, Farren J., Kuiken, Todd, Lajoie, Marc, Lessor, Tracy, Lunshof, Jeantine, Maurano, Matthew T., Mitchell, Leslie A., Rine, Jasper, Rosser, Susan, Sanjana, Neville E., Silver, Pamela A., Valle, David, Wang, Harris, Way, Jeffrey C., Yang, Luhan

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Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement von Isaacs, Farren J., Carr, Peter A., Wang, Harris H., Lajoie, Marc J., Sterling, Bram, Kraal, Laurens, Tolonen, Andrew C., Gianoulis, Tara A., Goodman, Daniel B., Reppas, Nikos B., Emig, Christopher J., Bang, Duhee, Hwang, Samuel J., Jewett, Michael C., Jacobson, Joseph M., Church, George M.

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Rapid editing and evolution of bacterial genomes using libraries of synthetic DNA von Gallagher, Ryan R, Li, Zhe, Lewis, Aaron O, Isaacs, Farren J

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Protein nanowires with tunable functionality and programmable self-assembly using sequence-controlled synthesis von Shapiro, Daniel Mark, Mandava, Gunasheil, Yalcin, Sibel Ebru, Arranz-Gibert, Pol, Dahl, Peter J., Shipps, Catharine, Gu, Yangqi, Srikanth, Vishok, Salazar-Morales, Aldo I., O’Brien, J. Patrick, Vanderschuren, Koen, Vu, Dennis, Batista, Victor S., Malvankar, Nikhil S., Isaacs, Farren J.

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Multilayered genetic safeguards limit growth of microorganisms to defined environments von Gallagher, Ryan R, Patel, Jaymin R, Interiano, Alexander L, Rovner, Alexis J, Isaacs, Farren J

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A flexible codon in genomically recoded Escherichia coli permits programmable protein phosphorylation von Pirman, Natasha L., Barber, Karl W., Aerni, Hans R., Ma, Natalie J., Haimovich, Adrian D., Rogulina, Svetlana, Isaacs, Farren J., Rinehart, Jesse

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Metagenomics harvested genus-specific single-stranded DNA-annealing proteins improve and expand recombineering in Pseudomonas species von Asin-Garcia, Enrique, Garcia-Morales, Luis, Bartholet, Tessa, Liang, Zhuobin, Isaacs, Farren J, Martins dos Santos, Vitor A P

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Precise manipulation of bacterial chromosomes by conjugative assembly genome engineering von Ma, Natalie J, Moonan, Daniel W, Isaacs, Farren J

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Tracking, tuning, and terminating microbial physiology using synthetic riboregulators von Callura, Jarred M., Dwyer, Daniel J., Isaacs, Farren J., Cantor, Charles R., Collins, James J.

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Encoding human serine phosphopeptides in bacteria for proteome-wide identification of phosphorylation-dependent interactions von Barber, Karl W, Muir, Paul, Szeligowski, Richard V, Rogulina, Svetlana, Gerstein, Mark, Sampson, Jeffrey R, Isaacs, Farren J, Rinehart, Jesse

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Crystal Structure of an Insect Antifreeze Protein and Its Implications for Ice Binding von Hakim, Aaron, Nguyen, Jennifer B., Basu, Koli, Zhu, Darren F., Thakral, Durga, Davies, Peter L., Isaacs, Farren J., Modis, Yorgo, Meng, Wuyi

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Genomic Recoding Broadly Obstructs the Propagation of Horizontally Transferred Genetic Elements von Ma, Natalie Jing, Isaacs, Farren J.

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