Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation von Huang, Chuanxin, Geng, Huimin, Boss, Isaac, Wang, Ling, Melnick, Ari

Volltext

The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development von Ortega-Molina, Ana, Boss, Isaac W, Canela, Andres, Pan, Heng, Jiang, Yanwen, Zhao, Chunying, Jiang, Man, Hu, Deqing, Agirre, Xabier, Niesvizky, Itamar, Lee, Ji-Eun, Chen, Hua-Tang, Ennishi, Daisuke, Scott, David W, Mottok, Anja, Hother, Christoffer, Liu, Shichong, Cao, Xing-Jun, Tam, Wayne, Shaknovich, Rita, Garcia, Benjamin A, Gascoyne, Randy D, Ge, Kai, Shilatifard, Ali, Elemento, Olivier, Nussenzweig, Andre, Melnick, Ari M, Wendel, Hans-Guido

Volltext

Kaposi's Sarcoma-Associated Herpesvirus Encodes an Ortholog of miR-155 von SKALSKY, Rebecca L, SAMOLS, Mark A, PLAISANCE, Karlie B, BOSS, Isaac W, RIVA, Alberto, LOPEZ, M. Cecilia, BAKER, Henry V, RENNE, Rolf

Volltext

Viral miRNAs and immune evasion von Boss, Isaac W., Renne, Rolf

Volltext

Viral miRNAs: tools for immune evasion von Boss, Isaac W, Renne, Rolf

Volltext

Role of virus-encoded microRNAs in herpesvirus biology von Boss, Isaac W, Plaisance, Karlie B, Renne, Rolf

Volltext

KSHV miRNAs decrease expression of lytic genes in latently infected PEL and endothelial cells by targeting host transcription factors von Plaisance-Bonstaff, Karlie, Choi, Hong Seok, Beals, Tyler, Krueger, Brian J, Boss, Isaac W, Gay, Lauren A, Haecker, Irina, Hu, Jianhong, Renne, Rolf

Volltext

A systems biology approach identified different regulatory networks targeted by KSHV miR-K12-11 in B cells and endothelial cells von Yang, Yajie, Boss, Isaac W, McIntyre, Lauren M, Renne, Rolf

Volltext

P825: SOLUBLE FACTORS CORRELATED WITH CYTOKINE RELEASE SYNDROME (CRS) WITH IV VS SUBCUTANEOUS (SC) ALNUCTAMAB (ALNUC; BMS‐986349; CC‐93269) IN PATIENTS WITH RELAPSED/REFRACTORY MUL... von Boss, Isaac, Thompson, Ethan, Gaudy, Allison, Vu, Thi Minh Diem, Godwin, Colin, Burgess, Michael, Wong, Sandy W., Costa, Luciano

Volltext

P799: SYNERGISTIC ANTITUMOR ACTIVITY OF THE BCMA 2 + 1 T CELL ENGAGER (TCE) ALNUCTAMAB (ALNUC; BMS‐986349; CC‐93269) AND CELMOD AGENTS IN MULTIPLE MYELOMA (MM) PRECLINICAL MODELS... von Paiva, Bruno, Gaffney, Bonny, Burnett, Kelven, Castiglioni, Paola, Angelo, Michael, Pierce, Daniel W., Boss, Isaac

Volltext

VII. Are lymphomas driven by epigenetic lesions? von Boss, Isaac W., Melnick, Ari M.

Volltext

A Kaposi's Sarcoma-Associated Herpesvirus-Encoded Ortholog of MicroRNA miR-155 Induces Human Splenic B-Cell Expansion in NOD/LtSz-scid IL2Rγnull Mice von BOSS, Isaac W, NADEAU, Peter E, ABBOTT, Jeffrey R, YAJIE YANG, MERGIA, Ayalew, RENNE, Rolf

Volltext

P883: ALNUCTAMAB (ALNUC; BMS‐986349; CC‐93269), A BCMA × CD3 T‐CELL ENGAGER, IN PATIENTS (PTS) WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM): LATEST RESULTS FROM A PHASE 1 FIRST... von Wong, Sandy W., Bar, Noffar, Victoria Mateos, María, Ribas, Paz, Hansson, Markus, Paris, Laura, Hofmeister, Craig, Rodriguez‐Otero, Paula, Aranzazu Bermúdez, Maria, Santoro, Armando, Yee, Andrew J., Creignou, Maria, Encinas, Cristina, Cerchione, Claudio, Rubia, Javier, Oriol, Albert, Ferstl, Barbara, Besemer, Britta, Chen, Jinjie, Chung, Alexander, Boss, Isaac W., Gaudy, Allison, LI, Shaoyi, Hsu, Kevin, Godwin, Colin, Burgess, Michael R., San‐Miguel, Jesús, Jose Costa, Luciano

Volltext

Synergistic Antitumor Activity of Alnuctamab (ALNUC; BMS-986349; CC-93269), a BCMA 2+1 T Cell Engager (TCE), and Celmod Agents in Multiple Myeloma (MM) Preclinical Models von Paiva, Bruno, Gaffney, Bonny, Burnett, Kelven, Castiglioni, Paola, Angelo, Michael, Pierce, Daniel W., Boss, Isaac W.

Volltext

Suppression of Myeloid Cell-Derived Proinflammatory Cytokines with Celmod Agents: Implications for CRS with T-Cell Engagers (TCEs) von Jeyaraju, Danny V, Alapa, Maryam, O'Donohue, Aimee, La Motte-Mohs, Ross, Boss, Isaac W., Hagner, Patrick, Pourdehnad, Michael, Burgess, Michael R., Pierceall, William E., Thakurta, Anjan

Volltext

Mezigdomide (CC-92480), a Novel Cereblon E3 Ligase Modulator, Induces Vulnerability of Multiple Myeloma Cells to T-Cell-Mediated Killing von Gaffney, Bonny, Shi, Yu, de Jong, Petrus, Sanchez, Manuel, Fontanillo, Celia, Lopez-Girona, Antonia, Boss, Isaac W., Kurtova, Antonina, Carrancio, Soraya, Wong, Lilly, Pierce, Daniel W.

Volltext

Soluble Factors Correlated with High-Grade Cytokine Release Syndrome (CRS): A Comparison of Subcutaneous (SC) Versus Intravenous (IV) Delivery of Alnuctamab (ALNUC; BMS-986349; CC-... von Boss, Isaac W., Thompson, Ethan, Gaudy, Allison M., Vu, Minh Diem, Godwin, Colin D., Burgess, Michael R., Wong, Sandy W., Costa, Luciano J.

Volltext

Prognostic implications of mono-hit and multi-hit TP53 alterations in patients with acute myeloid leukemia and higher risk myelodysplastic syndromes treated with azacitidine-based... von Zeidan, Amer M., Bewersdorf, Jan Philipp, Hasle, Vanessa, Shallis, Rory M., Thompson, Ethan, de Menezes, Daniel Lopes, Rose, Shelonidta, Boss, Isaac, Halene, Stephanie, Haferlach, Torsten, Fox, Brian

Volltext

Immune and Epigenetic Landscape of TP53-mutated Acute Myeloid Leukemia (AML) and Higher-Risk Myelodysplastic Syndromes (HR-MDS) von Zeidan, Amer M., Bewersdorf, Jan Philipp Philipp, Hasle, Vanessa, Thompson, Ethan G., Lopes de Menezes, Daniel, Rose, Shelonitda, Boss, Isaac, Fox, Brian

Volltext

P-025 Synergistic antitumor activity of the BCMA 2+1 T-cell engager (TCE) alnuctamab (ALNUC; BMS-986349; CC-93269) and CELMoD agents in multiple myeloma (MM) preclinical models von Paiva, Bruno, Gaffney, Bonny, Burnett, Kelven, Castiglioni, Paola, La Motte-Mohs, Ross, Angelo, Michael, Pierce, Daniel, Boss, Isaac

Volltext