Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies von Harley, Isaac T. W., Kaufman, Kenneth M., Langefeld, Carl D., Harley, John B., Kelly, Jennifer A.

Volltext

SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression von Hou, Guojun, Harley, Isaac T. W., Lu, Xiaoming, Zhou, Tian, Xu, Ning, Yao, Chao, Qin, Yuting, Ouyang, Ye, Ma, Jianyang, Zhu, Xinyi, Yu, Xiang, Xu, Hong, Dai, Dai, Ding, Huihua, Yin, Zhihua, Ye, Zhizhong, Deng, Jun, Zhou, Mi, Tang, Yuanjia, Namjou, Bahram, Guo, Ya, Weirauch, Matthew T., Kottyan, Leah C., Harley, John B., Shen, Nan

Volltext

GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network von Namjou, Bahram, Lingren, Todd, Huang, Yongbo, Parameswaran, Sreeja, Cobb, Beth L, Stanaway, Ian B, Connolly, John J, Mentch, Frank D, Benoit, Barbara, Niu, Xinnan, Wei, Wei-Qi, Carroll, Robert J, Pacheco, Jennifer A, Harley, Isaac T W, Divanovic, Senad, Carrell, David S, Larson, Eric B, Carey, David J, Verma, Shefali, Ritchie, Marylyn D, Gharavi, Ali G, Murphy, Shawn, Williams, Marc S, Crosslin, David R, Jarvik, Gail P, Kullo, Iftikhar J, Hakonarson, Hakon, Li, Rongling, Xanthakos, Stavra A, Harley, John B

Volltext

bakR: uncovering differential RNA synthesis and degradation kinetics transcriptome-wide with Bayesian hierarchical modeling von Vock, Isaac W, Simon, Matthew D

Volltext

Solar gamma ray constraints on dark matter annihilation to secluded mediators von Bell, Nicole F., Dent, James B., Sanderson, Isaac W.

Volltext

Synchronous tracheostomy and gastrostomy placement results in shorter length of stay in traumatic brain injury patients von Hochu, Gabrielle, Soule, Sara, Lenart, Emily, Howley, Isaac W, Filiberto, Dina, Byerly, Saskya

Volltext

Overlooked climate parameters best predict flowering onset: Assessing phenological models using the elastic net von Park, Isaac W., Mazer, Susan J.

Volltext

Metabolism at the crossroads of inflammation and fibrosis in chronic kidney disease von Miguel, Verónica, Shaw, Isaac W., Kramann, Rafael

Volltext

The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development von Ortega-Molina, Ana, Boss, Isaac W, Canela, Andres, Pan, Heng, Jiang, Yanwen, Zhao, Chunying, Jiang, Man, Hu, Deqing, Agirre, Xabier, Niesvizky, Itamar, Lee, Ji-Eun, Chen, Hua-Tang, Ennishi, Daisuke, Scott, David W, Mottok, Anja, Hother, Christoffer, Liu, Shichong, Cao, Xing-Jun, Tam, Wayne, Shaknovich, Rita, Garcia, Benjamin A, Gascoyne, Randy D, Ge, Kai, Shilatifard, Ali, Elemento, Olivier, Nussenzweig, Andre, Melnick, Ari M, Wendel, Hans-Guido

Volltext

Does inequality erode social trust? Results from multilevel models of US states and counties von Fairbrother, Malcolm, Martin, Isaac W.

Volltext

Relationships of climate, human activity, and fire history to spatiotemporal variation in annual fire probability across California von Park, Isaac W, Mann, Michael L, Flint, Lorraine E, Flint, Alan L, Moritz, Max

Volltext

Optical Coherence Tomography Angiography Evaluation of the Parafoveal Vasculature and Its Relationship With Ocular Factors von Tan, Colin S, Lim, Louis W, Chow, Vernon S, Chay, Isaac W, Tan, Shoun, Cheong, Kai Xiong, Tan, Gabriel T, Sadda, SriniVas R

Volltext

Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism von Smith, Lisa K, Babcock, Isaac W, Minamide, Laurie S, Shaw, Alisa E, Bamburg, James R, Kuhn, Thomas B

Volltext

Knowledge of Palliative Care Among American Adults: 2018 Health Information National Trends Survey von Huo, Jinhai, Hong, Young-Rock, Grewal, Reetu, Yadav, Sandhya, Heller, Isaac W., Bian, Jiang, Wilkie, Diana J.

Volltext

A Dual-Site Inhibitor of CBP/p300 KIX is a Selective and Effective Modulator of Myb von Joy, Stephen T., Henley, Madeleine J., De Salle, Samantha N., Beyersdorf, Matthew S., Vock, Isaac W., Huldin, Allison J. L., Mapp, Anna K.

Volltext

Kaposi's Sarcoma-Associated Herpesvirus Encodes an Ortholog of miR-155 von SKALSKY, Rebecca L, SAMOLS, Mark A, PLAISANCE, Karlie B, BOSS, Isaac W, RIVA, Alberto, LOPEZ, M. Cecilia, BAKER, Henry V, RENNE, Rolf

Volltext

Timing the bloom season: a novel approach to evaluating reproductive phenology across distinct regional flora von Park, Isaac W.

Volltext

All the Earth will not remember: how geographic gaps structure the record of diversity and extinction von Krone, Isaac W., Magoulick, Katherine M., Yohler, Ryan M.

Volltext

Functional analysis of antigen presentation by enteric glial cells during intestinal inflammation von Brown, Ryan M., Le, Helen H., Babcock, Isaac W., Harris, Tajie H., Gaultier, Alban

Volltext

Caspase-1 in Cx3cr1-expressing cells drives an IL-18-dependent T cell response that promotes parasite control during acute Toxoplasma gondii infection von Babcock, Isaac W, Sibley, Lydia A, Labuzan, Sydney A, Cowan, Maureen N, Sethi, Ish, Alemu, Seblework, Kelly, Abigail G, Kovacs, Michael A, Lukens, John R, Harris, Tajie H

Volltext