Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia von Bell, Hayden L, Blair, Helen J, Singh, Mankaran, Moorman, Anthony V, Heidenreich, Olaf, van Delft, Frederik W, Lunec, John, Irving, Julie A E

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Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukemia von Irving, Julie A.E., Enshaei, Amir, Parker, Catriona A., Sutton, Rosemary, Kuiper, Roland P., Erhorn, Amy, Minto, Lynne, Venn, Nicola C., Law, Tamara, Yu, Jiangyan, Schwab, Claire, Davies, Rosanna, Matheson, Elizabeth, Davies, Alysia, Sonneveld, Edwin, den Boer, Monique L., Love, Sharon B., Harrison, Christine J., Hoogerbrugge, Peter M., Revesz, Tamas, Saha, Vaskar, Moorman, Anthony V.

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Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia von Houlston, Richard S, Papaemmanuil, Elli, Hosking, Fay J, Vijayakrishnan, Jayaram, Price, Amy, Olver, Bianca, Sheridan, Eammon, Kinsey, Sally E, Lightfoot, Tracy, Roman, Eve, Irving, Julie A E, Allan, James M, Tomlinson, Ian P, Taylor, Malcolm, Greaves, Mel

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The ability to cross the blood–cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts von Williams, Mark T.S., Yousafzai, Yasar M., Elder, Alex, Rehe, Klaus, Bomken, Simon, Frishman-Levy, Liron, Tavor, Sigal, Sinclair, Paul, Dormon, Katie, Masic, Dino, Perry, Tracey, Weston, Victoria J., Kearns, Pamela, Blair, Helen, Russell, Lisa J., Heidenreich, Olaf, Irving, Julie A.E., Izraeli, Shai, Vormoor, Josef, Graham, Gerard J., Halsey, Christina

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Combination p53 activation and BCL-xL/BCL-2 inhibition as a therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia von Bell, Hayden L., Blair, Helen J., Jepson Gosling, Samantha J., Galler, Martin, Astley, Daniel, Moorman, Anthony V., Heidenreich, Olaf, Veal, Gareth J., van Delft, Frederik W., Lunec, John, Irving, Julie A. E.

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Towards an understanding of the biology and targeted treatment of paediatric relapsed acute lymphoblastic leukaemia von Irving, Julie A. E.

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Risk factors and outcomes in children with high-risk B-cell precursor and T-cell relapsed acute lymphoblastic leukaemia: combined analysis of ALLR3 and ALL-REZ BFM 2002 clinical tr... von Eckert, Cornelia, Parker, Catriona, Moorman, Anthony V., Irving, Julie AE, Kirschner-Schwabe, Renate, Groeneveld-Krentz, Stefanie, Révész, Tamas, Hoogerbrugge, Peter, Hancock, Jeremy, Sutton, Rosemary, Henze, Guenter, Chen-Santel, Christiane, Attarbaschi, Andishe, Bourquin, Jean-Pierre, Sramkova, Lucie, Zimmermann, Martin, Krishnan, Shekhar, von Stackelberg, Arend, Saha, Vaskar

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Levels of glucocorticoid receptor and its ligand determine sensitivity and kinetics of glucocorticoid-induced leukemia apoptosis von Gruber, G, Carlet, M, Türtscher, E, Meister, B, Irving, J A E, Ploner, C, Kofler, R

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SH2B3 inactivation through CN-LOH 12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain von Sinclair, Paul B., Ryan, Sarra, Bashton, Matthew, Hollern, Shaun, Hanna, Rebecca, Case, Marian, Schwalbe, Edward C., Schwab, Claire J., Cranston, Ruth E., Young, Brian D., Irving, Julie A. E., Vora, Ajay J., Moorman, Anthony V., Harrison, Christine J.

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Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor von Schmidt, Stefan, Irving, Julie A.E, Minto, Lynne, Matheson, Elizabeth, Nicholson, Lindsay, Ploner, Andreas, Parson, Walther, Kofler, Anita, Amort, Melanie, Erdel, Martin, Hall, Andy, Kofler, Reinhard

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Correction to: NF-κB mediates radio-sensitization by the PARP-1 inhibitor, AG-014699 von Hunter, J. E., Willmore, E., Irving, J. A. E., Hostomsky, Z., Veuger, S. J., Durkacz, B. W.

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DNA mismatch repair status affects cellular response to Ara-C and other anti-leukemic nucleoside analogs von Fordham, S E, Matheson, E C, Scott, K, Irving, J A E, Allan, J M

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Orexin-A, an hypothalamic peptide with analgesic properties von Bingham, S, Davey, P.T, Babbs, A.J, Irving, E.A, Sammons, M.J, Wyles, M, Jeffrey, P, Cutler, L, Riba, I, Johns, A, Porter, R.A, Upton, N, Hunter, A.J, Parsons, A.A

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Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia von Barone, F.C., Irving, E.A., Ray, A.M., Lee, J.C., Kassis, S., Kumar, S., Badger, A.M., Legos, J.J., Erhardt, J.A., Ohlstein, E.H., Hunter, A.J., Harrison, D.C., Philpott, K., Smith, B.R., Adams, J.L., Parsons, A.A.

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Typical 22q11.2 deletion syndrome appears to confer a reduced risk of schwannoma von Evans, D. Gareth, Messiaen, Ludwine M., Foulkes, William D., Irving, Rachel E. A., Murray, Alexandra J., Perez-Becerril, Cristina, Rivera, Barbara, McDonald-McGinn, Donna M., Stevenson, David A., Smith, Miriam J.

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A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with spe... von Sulong, Sarina, Moorman, Anthony V., Irving, Julie A.E., Strefford, Jonathan C., Konn, Zoe J., Case, Marian C., Minto, Lynne, Barber, Kerry E., Parker, Helen, Wright, Sarah L., Stewart, Adam R.M., Bailey, Simon, Bown, Nick P., Hall, Andrew G., Harrison, Christine J.

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Personalization of dexamethasone therapy in childhood acute lymphoblastic leukaemia von Jackson, Rosanna K., Irving, Julie A. E., Veal, Gareth J.

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X-ray-diffraction study of crystalline Si nanocluster formation in annealed silicon-rich silicon oxides von Comedi, D., Zalloum, O. H. Y., Irving, E. A., Wojcik, J., Roschuk, T., Flynn, M. J., Mascher, P.

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MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells von Brito, Jose L.R, Walker, Brian, Jenner, Matthew, Dickens, Nicholas J, Brown, Nicola J.M, Ross, Fiona M, Avramidou, Athanasia, Irving, Julie A.E, Gonzalez, David, Davies, Faith E, Morgan, Gareth J

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Common genetic variation contributes significantly to the risk of childhood B-cell precursor acute lymphoblastic leukemia von Enciso-Mora, V, Hosking, F J, Sheridan, E, Kinsey, S E, Lightfoot, T, Roman, E, Irving, J A E, Tomlinson, I P M, Allan, J M, Taylor, M, Greaves, M, Houlston, R S

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