Renal expression of exchange protein directly activated by cAMP (Epac) 1 and 2 von Li, Yuedan, Konings, Irene B. M, Zhao, Jun, Price, Leo S, de Heer, Emile, Deen, Peter M. T

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Short-Chain Ubiquitination Mediates the Regulated Endocytosis of the Aquaporin-2 Water Channel von Kamsteeg, Erik-Jan, Hendriks, Giel, Boone, Michelle, Konings, Irene B. M., Oorschot, Viola, van der Sluijs, Peter, Klumperman, Judith, Deen, Peter M. T.

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p.R254Q mutation in the aquaporin-2 water channel causing dominant nephrogenic diabetes insipidus is due to a lack of arginine vasopressin-induced phosphorylation von Savelkoul, Paul JM, De Mattia, Fabrizio, Li, Yuedan, Kamsteeg, Erik-Jan, Konings, Irene BM, van der Sluijs, Peter, Deen, Peter MT

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The Localization of Alpha-synuclein in the Endocytic Pathway von Fakhree, Mohammad A.A., Konings, Irene B.M., Kole, Jeroen, Cambi, Alessandra, Blum, Christian, Claessens, Mireille M.A.E.

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MAL decreases the internalization of the aquaporin-2 water channel von Kamsteeg, Erik-Jan, Duffield, Amy S, Konings, Irene B.M, Spencer, Joanna, Pagel, Philipp, Deen, Peter M.T, Caplan, Michael J

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Cell-biologic and functional analyses of five new Aquaporin-2 missense mutations that cause recessive nephrogenic diabetes insipidus von MARR, Nannette, BICHET, Daniel G, KNOERS, Nine V. A. M, LANDAU, Daniel, BALFE, William J, OKSCHE, Alexander, ROSENTHAL, Walter, MÜLLER, Dominik, VAN OS, Carel H, DEEN, Peter M. T, HOEFS, Susan, SAVELKOUL, Paul J. M, KONINGS, Irene B. M, DE MATTIA, Fabrizio, GRAAT, Michael P. J, ARTHUS, Marie-Francoise, LONERGAN, Michele, FUJIWARA, T. Mary

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Functionally different α-synuclein inclusions yield insight into Parkinson’s disease pathology von Raiss, Christian C., Braun, Theresa S., Konings, Irene B. M., Grabmayr, Heinrich, Hassink, Gerco C., Sidhu, Arshdeep, le Feber, Joost, Bausch, Andreas R., Jansen, Casper, Subramaniam, Vinod, Claessens, Mireille M. A. E.

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Missorting of the Aquaporin-2 mutant E258K to multivesicular bodies/lysosomes in dominant NDI is associated with its monoubiquitination and increased phosphorylation by PKC but is... von Kamsteeg, Erik-Jan, Savelkoul, Paul J. M., Hendriks, Giel, Konings, Irene B. M., Nivillac, Nicole M. I., Lagendijk, Anne Karine, van der Sluijs, Peter, Deen, Peter M. T.

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Repulsion between Lys258 and upstream arginines explains the missorting of the AQP2 mutant p.Glu258Lys in nephrogenic diabetes insipidus von Kamsteeg, Erik-Jan, Stoffels, Monique, Tamma, Grazia, Konings, Irene B.M, Deen, Peter M.T

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Quaternary ammonium compounds as water channel blockers. Specificity, potency, and site of action von Detmers, Frank J M, de Groot, Bert L, Müller, E Matthias, Hinton, Andrew, Konings, Irene B M, Sze, Mozes, Flitsch, Sabine L, Grubmüller, Helmut, Deen, Peter M T

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A novel mechanism in recessive nephrogenic diabetes insipidus: wild-type aquaporin-2 rescues the apical membrane expression of intracellularly retained AQP2-P262L von de Mattia, Fabrizio, Savelkoul, Paul J.M., Bichet, Daniel G., Kamsteeg, Erik-Jan, Konings, Irene B.M., Marr, Nannette, Arthus, Marie-Françoise, Lonergan, Michèle, van Os, Carel H., van der Sluijs, Peter, Robertson, Gary, Deen, Peter M.T.

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Lack of arginine vasopressin-induced phosphorylation of aquaporin-2 mutant AQP2-R254L explains dominant nephrogenic diabetes insipidus von DE MATTIA, Fabrizio, SAVELKOUL, Paul J. M, KAMSTEEG, Erik-Jan, KONINGS, Irene B. M, VAN DER SLUIJS, Peter, MALLMANN, Rudolf, OKSCHE, Alexander, DEEN, Peter M. T

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Reversed Polarized Delivery of an Aquaporin-2 Mutant Causes Dominant Nephrogenic Diabetes Insipidus von Kamsteeg, Erik-Jan, Bichet, Daniel G., Irene B. M. Konings, Nivet, Hubert, Lonergan, Michelle, Arthus, Marie-Françoise, van Os, Carel H., Peter M. T. Deen

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Polarisation, key to good localisation von van Beest, Moniek, Robben, Joris H., Savelkoul, Paul J.M., Hendriks, Giel, Devonald, Mark A.J., Konings, Irene B.M., Lagendijk, Anne K., Karet, Fiona, Deen, Peter M.T.

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Novel PTEN mutations in patients with Cowden disease: absence of clear genotype-phenotype correlations von Nelen, M R, Kremer, H, Konings, I B, Schoute, F, van Essen, A J, Koch, R, Woods, C G, Fryns, J P, Hamel, B, Hoefsloot, L H, Peeters, E A, Padberg, G W

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Functionally different [alpha]-synuclein inclusions yield insight into Parkinson's disease pathology von Raiss, Christian C, Braun, Theresa S, Konings, Irene B M, Grabmayr, Heinrich, Hassink, Gerco C, Sidhu, Arshdeep, Le Feber, Joost, Bausch, Andreas R, Jansen, Casper, Subramaniam, Vinod, Claessens, Mireille M A E

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Renal expression of exchange protein directly activated by cAMP (Epac) 1 and 2 von YUEDAN LI, KONINGS, Irene B. M, JUN ZHAO, PRICE, Leo S, DE HEER, Emile, DEEN, Peter M. T

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Changing S261, including constitutive phosphorylation, enhances AQP2 ubiquitination and internalization von Deen, Peter MT, Tamma, Grazia, Stoffels, Monique, Hoffert, Jason D, Konings, Irene BM, Knepper, Mark A

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Quaternary Ammonium Compounds as Water Channel Blockers von Detmers, Frank J.M., de Groot, Bert L., Müller, E. Matthias, Hinton, Andrew, Konings, Irene B.M., Sze, Mozes, Flitsch, Sabine L., Grubmüller, Helmut, Deen, Peter M.T.

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Missorting to late endosome/lysosomes due to increased phosphorylation by protein kinase C and mono‐ubiquitination of the Aquaporin‐2 mutant E258K might explain its role in dominan... von Deen, Peter MT, Savelkoul, Paul JM, Kamsteeg, Erik‐Jan, Hendriks, Giel, Konings, Irene BM, van der Sluijs, Peter

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