Discovery of potent broad spectrum antivirals derived from marine actinobacteria von Raveh, Avi, Delekta, Phillip C, Dobry, Craig J, Peng, Weiping, Schultz, Pamela J, Blakely, Pennelope K, Tai, Andrew W, Matainaho, Teatulohi, Irani, David N, Sherman, David H, Miller, David J

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inflammatory cytokine, interleukin-1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic motor neuron injury in the spinal cord during acute viral encephal... von Prow, Natalie A, Irani, David N

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Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis von Morris, Aaron H., Hughes, Kevin R., Oakes, Robert S., Cai, Michelle M., Miller, Stephen D., Irani, David N., Shea, Lonnie D.

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Dysregulation of the IL-23/IL-17 axis and myeloid factors in secondary progressive MS von Huber, Amanda K, Wang, Lu, Han, Peisong, Zhang, Xu, Ekholm, Sven, Srinivasan, Ashok, Irani, David N, Segal, Benjamin M

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Type-I interferons suppress microglial production of the lymphoid chemokine, CXCL13 von Esen, Nilufer, Rainey-Barger, Emily K., Huber, Amanda K., Blakely, Pennelope K., Irani, David N.

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Progressive multifocal leukoencephalopathy selectively affecting Broca's and Wernicke's areas in an immunocompetent patient: A case report von Kim, Renaid B., Irani, David N., Kim, John

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Astrocyte matricellular proteins that control excitatory synaptogenesis are regulated by inflammatory cytokines and correlate with paralysis severity during experimental autoimmune... von Blakely, Pennelope K, Hussain, Shabbir, Carlin, Lindsey E, Irani, David N

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Optimization of Novel Indole-2-carboxamide Inhibitors of Neurotropic Alphavirus Replication von Sindac, Janice A, Barraza, Scott J, Dobry, Craig J, Xiang, Jianming, Blakely, Pennelope K, Irani, David N, Keep, Richard F, Miller, David J, Larsen, Scott D

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An emerging role for eotaxins in neurodegenerative disease von Huber, Amanda K, Giles, David A, Segal, Benjamin M, Irani, David N

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Is the concept of central nervous system immune privilege irrelevant in the setting of acute infection? von Huber, Amanda K, Irani, David N

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Neuroprotective Interventions Targeting Detrimental Host Immune Responses Protect Mice From Fatal Alphavirus Encephalitis von Irani, David N, Prow, Natalie A

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Viral-Induced Spinal Motor Neuron Death Is Non-Cell-Autonomous and Involves Glutamate Excitotoxicity von Darman, Jessica, Backovic, Stephanie, Dike, Sonny, Maragakis, Nicholas J, Krishnan, Chitra, Rothstein, Jeffrey D, Irani, David N, Kerr, Douglas A

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Complexity of the microglial activation pathways that drive innate host responses during lethal alphavirus encephalitis in mice von Esen, Nilufer, Blakely, Pennelope K, Rainey-Barger, Emily K, Irani, David N

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Cerebrospinal fluid protein carbonylation identifies oxidative damage in autoimmune demyelination von Irani, David N.

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Type-1 angiotensin receptor signaling in central nervous system myeloid cells is pathogenic during fatal alphavirus encephalitis in mice von Blakely, Pennelope K, Huber, Amanda K, Irani, David N

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Loss of the Ubiquitin-conjugating Enzyme UBE2W Results in Susceptibility to Early Postnatal Lethality and Defects in Skin, Immune, and Male Reproductive Systems von Wang, Bo, Merillat, Sean A., Vincent, Michael, Huber, Amanda K., Basrur, Venkatesha, Mangelberger, Doris, Zeng, Li, Elenitoba-Johnson, Kojo, Miller, Richard A., Irani, David N., Dlugosz, Andrzej A., Schnell, Santiago, Scaglione, Kenneth Matthew, Paulson, Henry L.

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Inflammatory bowel disease patient concerns and experiences on transition to home-based infusions during the COVID-19 pandemic von Jacob, Janson, Aintabi, Daniel, DeJonckheere, Melissa, Cohen-Mekelburg, Shirley A., Allen, John I., Irani, David N., Fendrick, A. Mark, Waljee, Akbar K., Higgins, Peter D.R., Berinstein, Jeffrey A.

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Human Embryonic Germ Cell Derivatives Facilitate Motor Recovery of Rats with Diffuse Motor Neuron Injury von Kerr, Douglas A, Llado, Jeronia, Shamblott, Michael J, Maragakis, Nicholas J, Irani, David N, Crawford, Thomas O, Krishnan, Chitra, Dike, Sonny, Gearhart, John D, Rothstein, Jeffrey D

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The lymphoid chemokine, CXCL13, is dispensable for the initial recruitment of B cells to the acutely inflamed central nervous system von Rainey-Barger, Emily K, Rumble, Julie M, Lalor, Stephen J, Esen, Nilufer, Segal, Benjamin M, Irani, David N

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The conundrum of interferon-β non-responsiveness in relapsing–remitting multiple sclerosis von Huber, Amanda K., Duncker, Patrick C., Irani, David N.

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