Senescence in RASopathies, a possible novel contributor to a complex pathophenoype von Engler, Melanie, Fidan, Miray, Nandi, Sayantan, Cirstea, Ion Cristian

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Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome von Busley, Alexandra Viktoria, Gutiérrez-Gutiérrez, Óscar, Hammer, Elke, Koitka, Fabian, Mirzaiebadizi, Amin, Steinegger, Martin, Pape, Constantin, Böhmer, Linda, Schroeder, Henning, Kleinsorge, Mandy, Engler, Melanie, Cirstea, Ion Cristian, Gremer, Lothar, Willbold, Dieter, Altmüller, Janine, Marbach, Felix, Hasenfuss, Gerd, Zimmermann, Wolfram-Hubertus, Ahmadian, Mohammad Reza, Wollnik, Bernd, Cyganek, Lukas

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Increased osteoclastogenesis contributes to bone loss in the Costello syndrome Hras G12V mouse model von Nandi, Sayantan, Chennappan, Saravanakkumar, Andrasch, Yannik, Fidan, Miray, Engler, Melanie, Ahmad, Mubashir, Tuckermann, Jan P., Zenker, Martin, Cirstea, Ion Cristian

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Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing von Ahmad, Mubashir, Krüger, Benjamin Thilo, Kroll, Torsten, Vettorazzi, Sabine, Dorn, Ann-Kristin, Mengele, Florian, Lee, Sooyeon, Nandi, Sayantan, Yilmaz, Dilay, Stolz, Miriam, Tangudu, Naveen Kumar, Vázquez, David Carro, Pachmayr, Johanna, Cirstea, Ion Cristian, Spasic, Maja Vujic, Ploubidou, Aspasia, Ignatius, Anita, Tuckermann, Jan

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Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial card... von Nakhaei-Rad, Saeideh, Haghighi, Fereshteh, Bazgir, Farhad, Dahlmann, Julia, Busley, Alexandra Viktoria, Buchholzer, Marcel, Kleemann, Karolin, Schänzer, Anne, Borchardt, Andrea, Hahn, Andreas, Kötter, Sebastian, Schanze, Denny, Anand, Ruchika, Funk, Florian, Kronenbitter, Annette Vera, Scheller, Jürgen, Piekorz, Roland P., Reichert, Andreas S., Volleth, Marianne, Wolf, Matthew J., Cirstea, Ion Cristian, Gelb, Bruce D., Tartaglia, Marco, Schmitt, Joachim P., Krüger, Martina, Kutschka, Ingo, Cyganek, Lukas, Zenker, Martin, Kensah, George, Ahmadian, Mohammad R.

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Studying Metabolic Abnormalities in the Costello Syndrome HRAS G12V Mouse Model: Isolation of Mouse Embryonic Fibroblasts and Their In Vitro Adipocyte Differentiation von Fidan, Miray, Chennappan, Saravanakkumar, Cirstea, Ion Cristian

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Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders von Gremer, Lothar, Merbitz-Zahradnik, Torsten, Dvorsky, Radovan, Cirstea, Ion C., Kratz, Christian Peter, Zenker, Martin, Wittinghofer, Alfred, Ahmadian, Mohammad Reza

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The glucocorticoid receptor associates with RAS complexes to inhibit cell proliferation and tumor growth von Caratti, Bozhena, Fidan, Miray, Caratti, Giorgio, Breitenecker, Kristina, Engler, Melanie, Kazemitash, Naser, Traut, Rebecca, Wittig, Rainer, Casanova, Emilio, Ahmadian, Mohammad Reza, Tuckermann, Jan P, Moll, Herwig P, Cirstea, Ion Cristian

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ACE2-EGFR-MAPK signaling contributes to SARS-CoV-2 infection von Engler, Melanie, Albers, Dan, Von Maltitz, Pascal, Groß, Rüdiger, Münch, Jan, Cirstea, Ion Cristian

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Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice von Kraft, Michael, Cirstea, Ion Cristian, Voss, Anne Kathrin, Thomas, Tim, Goehring, Ina, Sheikh, Bilal N, Gordon, Lavinia, Scott, Hamish, Smyth, Gordon K, Ahmadian, Mohammad Reza, Trautmann, Udo, Zenker, Martin, Tartaglia, Marco, Ekici, Arif, Reis, André, Dörr, Helmuth-Guenther, Rauch, Anita, Thiel, Christian Thomas

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Artificial linear episome-based protein expression system for protozoon Leishmania tarentolae von Kushnir, Susanna, Cirstea, Ion Cristian, Basiliya, Lyudmyla, Lupilova, Nataliya, Breitling, Reinhard, Alexandrov, Kirill

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Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing von Mubashir Ahmad, Benjamin Thilo Krüger, Torsten Kroll, Sabine Vettorazzi, Ann-Kristin Dorn, Florian Mengele, Sooyeon Lee, Sayantan Ni, Dilay Yilmaz, Miriam Stolz, Naveen Kumar Tangudu, David Carro Vázquez, Johanna Pachmayr, Ion Cristian Cirstea, Maja Vujic Spasic, Aspasia Ploubidou, Anita Ignatius, Jan Tuckermann

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Ras Activity and Signaling: Methods and Protocols von Rubio, Ignacio, Prior, Ian

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Purification and crystallization of human Cu/Zn superoxide dismutase recombinantly produced in the protozoan Leishmania tarentolae von Gazdag, Emerich Mihai, Cirstea, Ion Cristian, Breitling, Reinhard, Lukeš, Julius, Blankenfeldt, Wulf, Alexandrov, Kirill

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Development of approaches for the engineering of gene expression in the protozoa Leishmania tarentolae

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