Mendelian randomization highlights causal association between genetically increased C‐reactive protein levels and reduced Alzheimer's disease risk von Hu, Yang, Zhang, Yan, Zhang, Haihua, Gao, Shan, Wang, Longcai, Wang, Tao, Han, Zhifa, Liu, Guiyou

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GENOME-WIDE META-ANALYSIS OF LATE-ONSET ALZHEIMER’S DISEASE USING RARE VARIANT IMPUTATION IN 64,859 SUBJECTS IDENTIFIES RISK LOCI WITH ROLES IN INNATE IMMUNITY AND CARDIOVASCULAR T... von Naj, Adam, Sha, Jin, Leonenko, Ganna, Chen, Yuning, Chouraki, Vincent, Leber, Markus, Sims, Rebecca, Grenier-Boley, Benjamin, Bis, Joshua C., Zhao, Yi, Kuzma, Amanda B., Kunkle, Brian W., Karamujić-Čomić, Hata, Van Der Lee, Sven J., Bellenguez, Celine, Frizzati, Aura, Holmans, Peter, Dupuis, Josée, Wang, Li-San, Farrer, Lindsay A., van Duijn, Cornelia M., Haines, Jonathan L., Destefano, Anita L., Pericak-Vance, Margaret A., Ramirez, Alfredo, Amouyel, Philippe, Lambert, Jean-Charles, Seshadri, Sudha, Williams, Julie, Schellenberg, Gerard D.

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O2‐10‐06: GENOME‐WIDE META‐ANALYSIS OF LATE‐ONSET ALZHEIMER'S DISEASE USING RARE VARIANT IMPUTATION IN 64,859 SUBJECTS IDENTIFIES RISK LOCI WITH ROLES IN INNATE IMMUNITY AND CARDIO... von Naj, Adam, Sha, Jin, Leonenko, Ganna, Chen, Yuning, Chouraki, Vincent, Leber, Markus, Sims, Rebecca, Grenier-Boley, Benjamin, Bis, Joshua C., Zhao, Yi, Kuzma, Amanda B., Kunkle, Brian W., Karamujić-Čomić, Hata, Van Der Lee, Sven J., Bellenguez, Celine, Frizzati, Aura, Holmans, Peter, Dupuis, Josée, Wang, Li-San, Farrer, Lindsay A., Duijn, Cornelia M., Haines, Jonathan L., Destefano, Anita L., Pericak-Vance, Margaret A., Ramirez, Alfredo, Amouyel, Philippe, Lambert, Jean-Charles, Seshadri, Sudha, Williams, Julie, Schellenberg, Gerard D.

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SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease von Ramirez, Alfredo, van der Flier, Wiesje M, Herold, Christine, Ramonet, David, Heilmann, Stefanie, Lewczuk, Piotr, Popp, Julius, Lacour, André, Drichel, Dmitriy, Louwersheimer, Eva, Kummer, Markus P, Cruchaga, Carlos, Hoffmann, Per, Teunissen, Charlotte, Holstege, Henne, Kornhuber, Johannes, Peters, Oliver, Naj, Adam C, Chouraki, Vincent, Bellenguez, Céline, Gerrish, Amy, Heun, Reiner, Frölich, Lutz, Hüll, Michael, Buscemi, Lara, Herms, Stefan, Kölsch, Heike, Scheltens, Philip, Breteler, Monique M, Rüther, Eckart, Wiltfang, Jens, Goate, Alison, Jessen, Frank, Maier, Wolfgang, Heneka, Michael T, Becker, Tim, Nöthen, Markus M

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Shared genetic contribution to ischemic stroke and Alzheimer's disease von Traylor, Matthew, Adib-Samii, Poneh, Harold, Denise, Dichgans, Martin, Williams, Julie, Lewis, Cathryn M., Markus, Hugh S.

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DT‐02‐02: Low‐frequency variant imputation identifies rare variant candidate loci in a gwas of late‐onset Alzheimer's disease in the igap consortium von Kunkle, Brian W., Grenier-Boley, Benjamin, Vronskaya, Maria, Chouraki, Vincent, Lee, Sven J., Hamilton-Nelson, Kara L., Toeglhofer, A.M., Sims, Rebecca, Jakobsdottir, Johanna, Bis, Joshua C., Dombroski, Beth A., Martin, Eden R., Mayeux, Richard, Farrer, Lindsay A., Duijn, Cornelia M., Haines, Jonathan L., Williams, Julie, Seshadri, Sudha, Amouyel, Philippe, Schellenberg, Gerard D., Pericak-Vance, Margaret A.

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Low-frequency variant imputation identifies rare variant candidate loci in a gwas of late-onset Alzheimer’s disease in the igap consortium von Kunkle, Brian W, Grenier-Boley, Benjamin, Vronskaya, Maria, Chouraki, Vincent, van der Lee, Sven J, Hamilton-Nelson, Kara L, Toeglhofer, A.M, Sims, Rebecca, Jakobsdottir, Johanna, Bis, Joshua C, Dombroski, Beth A, Martin, Eden R, Mayeux, Richard, Farrer, Lindsay A, van Duijn, Cornelia M, Haines, Jonathan L, Williams, Julie, Seshadri, Sudha, Amouyel, Philippe, Schellenberg, Gerard D, Pericak-Vance, Margaret A

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FUNCTIONAL VALIDATION OF NOVEL ALZHEIMER GENETIC RISK LOCI USING DROSOPHILA von Dourlen, Pierre, Dermaut, Bart, Grenier-Boley, Benjamin, Bellenguez, Céline, Dupont, Cloé, Abdelfettah, Farida, Schellenberg, Gerard D., Lambert, Jean-Charles, Williams, Julie, Amouyel, Philippe, Seshadri, Sudha

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EXOME CHIP META-ANALYSIS OF ALZHEIMER'S DISEASE IN THE IGAP CONSORTIUM von van der Lee, Sven J, Naj, Adam, van Duijn, Cornelia, Schellenberg, Gerard D, Jakobsdottir, Johanna, Williams, Julie, Wang, Li-San, Vronskaya, Maria, Amouyel, Philippe, Sims, Rebecca, Seshadri, Sudha

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DO THE VARIANTS IDENTIFIED IN IGAP IMPROVE RISK PREDICTION OF ALZHEIMER'S DISEASE? von Chouraki, Vincent Antoine, DeStefano, Anita, Bellenguez, Céline, Reitz, Christiane, van Duijn, Cornelia, Bennett, David, Maury, Fleur, Lambert, Jean-Charles, Jakobsdottir, Johanna, Bis, Joshua C, Launer, Lenore, Crane, Paul, Mayeux, Richard, Choi, Seung Hoan, Seshadri, Sudha

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COMPREHENSIVE GENE-GENE INTERACTION META-ANALYSIS OF IGAP GWA STUDIES von Becker, Tim, Ramirez, Alfredo, Herold, Christine, van Duijn, Cornelia, Schellenberg, Gerard D, Williams, Julie, Amouyel, Philippe, Yang, Qiong, Seshadri, Sudha, van der Lee, Sven J

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S1–01–02: The genetics of lipid metabolism in Alzheimer's disease susceptibility von Jones, Lesley, Holmans, Peter

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The genetics of lipid metabolism in Alzheimer's disease susceptibility von Jones, Lesley, Holmans, Peter

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Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease von Jakobsdottir, J., Raybould, R., Vronskaya, M., White, C.C., Herms, S., Smith, A.V., Funk, C.C., Sánchez-Juan, P., Wolters, F.J., Zhao, Y., Malamon, J., Dombroski, B., Whitehead, P., Cantwell, L.B., Burgess, J.D., Adams, H.H., Chakrabarty, P., Beiser, A.S., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Henández, I., Tarraga, L., Albert, M.S., Emilsson, V., Doody, R.S., Spalletta, G., Frosch, M.P., Kamboh, M.I., Marshall, R., Fairén, M.D., Uphill, J., Hughes, J.T., Orfei, M.D., Ciaramella, A., Mayhaus, M., Brookes, K., Cupidi, C., Gill, M., Apostolova, L.G., Asthana, S., Boeve, B.F., Burke, J.R., Buxbaum, J.D., Cairns, N.J., Chui, H.C., Gearing, M., Harrell, L.E., Jarvik, G.P., Leverenz, J.B., Li, G., Lieberman, A.P., McCormick, W.C., Miller, C.A., Pankratz, V.S., Raskind, M., Tanzi, R.E., Troncoso, J.C., Wingo, T.S., Garzia, F., Vandenberghe, R., Fernadez, C.M., Lilius, L., Koivisto, A.M., Dermecourt, V., Fievet, N., Brice, A., Ritchie, K., Dubois, B., Himali, J.J., Tschanz, J., Fitzpatrick, A.L., Kukull, W.A., Larson, E.B., Rotter, J.I., Coto, E., Gallo, M., Galimberti, D., Tsuang, D.W., Daniele, A., Nacmias, B., Rubinsztein, D.C., Bras, J., Collinge, J., Tsolaki, M., Uitterlinden, A.G., Powell, J., Golde, T.E., De Jager, P.L., Ertekin-Taner, N., Passmore, P., Younkin, S.G., Ortega-Cubero, S., Jones, L., Mayeux, R., Amin, N., Holmans, P.A., Pericak-Vance, M.A., Lambert, J.C., Destefano, Anita L.

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rs34331204 regulates TSPAN13 expression and contributes to Alzheimer's disease with sex differences von Hu, Yang, Zhang, Haihua, Liu, Bian, Gao, Shan, Wang, Tao, Han, Zhifa, Ji, Xunming, Liu, Guiyou

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Shared genetic contribution to Ischaemic Stroke and Alzheimer's Disease von Traylor, Matthew, Adib-Samii, Poneh, Harold, Denise, Dichgans, Martin, Williams, Julie, Lewis, Cathryn M, Markus, Hugh S

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Both clinically informed and brain region agnostic approaches identify neuroimaging derived phenotypes associated with genetically regulated gene expression of late‐onset Alzheimer... von Wang, Ting‐Chen, Bledsoe, Xavier, Shaw, Douglas, Chen, Hung‐Hsin, Naj, Adam C., Bush, William S., Gamazon, Eric J, Below, Jennifer E.

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CXCR4 involvement in neurodegenerative diseases von Bonham, Luke W., Karch, Celeste M., Fan, Chun C., Tan, Chin, Geier, Ethan G., Wang, Yunpeng, Wen, Natalie, Broce, Iris J., Li, Yi, Barkovich, Matthew J., Ferrari, Raffaele, Hardy, John, Momeni, Parastoo, Höglinger, Günter, Müller, Ulrich, Hess, Christopher P., Sugrue, Leo P., Dillon, William P., Schellenberg, Gerard D., Miller, Bruce L., Andreassen, Ole A., Dale, Anders M., Barkovich, A. James, Yokoyama, Jennifer S., Desikan, Rahul S.

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F4‐04‐04: FUNCTIONAL VALIDATION OF NOVEL ALZHEIMER GENETIC RISK LOCI USING DROSOPHILA von Dourlen, Pierre, Dermaut, Bart, Grenier‐Boley, Benjamin, Bellenguez, Céline, Dupont, Cloé, Abdelfettah, Farida, Schellenberg, Gerard D., International Genomics of Alzheimer's Project (IGAP), Lambert, Jean‐Charles, Williams, Julie, Amouyel, Philippe, Seshadri, Sudha

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F4‐04‐01: EXOME CHIP META‐ANALYSIS OF ALZHEIMER'S DISEASE IN THE IGAP CONSORTIUM von Lee, Sven J., Naj, Adam, Duijn, Cornelia, Schellenberg, Gerard D., International Genomics of Alzheimer's Project (IGAP), Jakobsdottir, Johanna, Williams, Julie, Wang, Li‐San, Vronskaya, Maria, Amouyel, Philippe, Sims, Rebecca, Seshadri, Sudha

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