ERK Inhibition: A New Front in the War against MAPK Pathway-Driven Cancers? von Smalley, Inna, Smalley, Keiran S M

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Single-cell Characterization of the Cellular Landscape of Acral Melanoma Identifies Novel Targets for Immunotherapy von Li, Jiannong, Smalley, Inna, Chen, Zhihua, Wu, Jheng-Yu, Phadke, Manali S, Teer, Jamie K, Nguyen, Thanh, Karreth, Florian A, Koomen, John M, Sarnaik, Amod A, Zager, Jonathan S, Khushalani, Nikhil I, Tarhini, Ahmad A, Sondak, Vernon K, Rodriguez, Paulo C, Messina, Jane L, Chen, Y Ann, Smalley, Keiran S M

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Noncanonical EphA2 Signaling Is a Driver of Tumor-Endothelial Cell Interactions and Metastatic Dissemination in BRAF Inhibitor‒Resistant Melanoma von Zhang, Chao, Smalley, Inna, Emmons, Michael F., Sharma, Ritin, Izumi, Victoria, Messina, Jane, Koomen, John M., Pasquale, Elena B., Forsyth, Peter A., Smalley, Keiran S.M.

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Factors associated with overall survival in breast cancer patients with leptomeningeal disease (LMD): a single institutional retrospective review von Wallace, Gerald, Kundalia, Ronak, Vallebuona, Ethan, Cao, Biwei, Kim, Youngchul, Forsyth, Peter, Soyano, Aixa, Smalley, Inna, Pina, Yolanda

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Dabrafenib inhibits the growth of BRAF‐WT cancers through CDK16 and NEK9 inhibition von Phadke, Manali, Remsing Rix, Lily L., Smalley, Inna, Bryant, Annamarie T., Luo, Yunting, Lawrence, Harshani R., Schaible, Braydon J., Chen, Yian A., Rix, Uwe, Smalley, Keiran S. M.

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Space Is the Place: Mapping the Cell–Cell Interactions That Predict Immunotherapy Responses in Melanoma von Smalley, Inna, Smalley, Keiran S.M.

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Single-Cell Characterization of the Immune Microenvironment of Melanoma Brain and Leptomeningeal Metastases von Smalley, Inna, Chen, Zhihua, Phadke, Manali, Li, Jiannong, Yu, Xiaoqing, Wyatt, Clayton, Evernden, Brittany, Messina, Jane L, Sarnaik, Amod, Sondak, Vernon K, Zhang, Chaomei, Law, Vincent, Tran, Nam, Etame, Arnold, Macaulay, Robert J B, Eroglu, Zeynep, Forsyth, Peter A, Rodriguez, Paulo C, Chen, Y Ann, Smalley, Keiran S M

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Proteomic Analysis of CSF from Patients with Leptomeningeal Melanoma Metastases Identifies Signatures Associated with Disease Progression and Therapeutic Resistance von Smalley, Inna, Law, Vincent, Wyatt, Clayton, Evernden, Brittany, Fang, Bin, Koomen, John M, Welsh, Eric A, Macaulay, Robert J B, Forsyth, Peter A, Smalley, Keiran S M

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Factors associated with overall survival in patients with melanoma leptomeningeal disease (M-LMD): A single institution retrospective review von Nyman, Karl, Kundalia, Ronak, Ospina, Oscar, Wallace, Gerald Carter, Pina, Yolanda, Smalley, Inna, Forsyth, Peter A. J.

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Combined BRAF, MEK, and heat‐shock protein 90 inhibition in advanced BRAF V600‐mutant melanoma von Eroglu, Zeynep, Chen, Y. Ann, Smalley, Inna, Li, Jiannong, Markowitz, Joseph K., Brohl, Andrew S., Tetteh, Leticia, Taylor, Hayley, Sondak, Vernon K., Khushalani, Nikhil I., Smalley, Keiran S. M.

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NCMP-04. COMBINATION BRAF/MEK INHIBITION IMPROVES SURVIVAL WITH LEPTOMENINGEAL DISEASE FROM MELANOMA IN A SINGLE INSTITUTIONAL REVIEW AT MOFFITT CANCER CENTER von Wallace, Gerald, Kundalia, Ronak, Imran, Amna, Smalley, Inna, Pina, Yolanda, Forsyth, Peter

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Leptomeningeal disease in melanoma patients: An update to treatment, challenges, and future directions von Glitza, Isabella C., Smalley, Keiran S. M., Brastianos, Priscilla K., Davies, Michael A., McCutcheon, Ian, Liu, James K. C., Ahmed, Kamran A., Arrington, John A., Evernden, Brittany R., Smalley, Inna, Eroglu, Zeynep, Khushalani, Nikhil, Margolin, Kim, Kluger, Harriet, Atkins, Michael B., Tawbi, Hussein, Boire, Adrienne, Forsyth, Peter

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HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma von Sriramareddy, Sathya Neelature, Faião-Flores, Fernanda, Emmons, Michael F., Saha, Biswarup, Chellappan, Srikumar, Wyatt, Clayton, Smalley, Inna, Licht, Jonathan D., Durante, Michael A., Harbour, J. William, Smalley, Keiran S. M.

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Leptomeningeal disease in melanoma: An update on the developments in pathophysiology and clinical care von Smalley, Inna, Boire, Adrienne, Brastianos, Priscilla, Kluger, Harriet M., Hernando‐Monge, Eva, Forsyth, Peter A., Ahmed, Kamran A., Smalley, Keiran S. M., Ferguson, Sherise, Davies, Michael A., Glitza Oliva, Isabella C.

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The biology and therapeutic management of melanoma brain metastases von Abate-Daga, Daniel, Ramello, Maria C., Smalley, Inna, Forsyth, Peter A., Smalley, Keiran S.M.

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spatialGE: quantification and visualization of the tumor microenvironment heterogeneity using spatial transcriptomics von Ospina, Oscar E, Wilson, Christopher M, Soupir, Alex C, Berglund, Anders, Smalley, Inna, Tsai, Kenneth Y, Fridley, Brooke L

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A preclinical model of patient-derived cerebrospinal fluid circulating tumor cells for experimental therapeutics in leptomeningeal disease from melanoma von Law, Vincent, Chen, Zhihua, Vena, Francesca, Smalley, Inna, Macaulay, Robert, Evernden, Brittany R, Tran, Nam, Pina, Yolanda, Puskas, John, Caceres, Gisela, Bayle, Simon, Johnson, Joseph, Liu, James K C, Etame, Arnold, Vogelbaum, Michael, Rodriguez, Paulo, Duckett, Derek, Czerniecki, Brian, Chen, Ann, Smalley, Keiran S M, Forsyth, Peter A

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Abstract 3025: Ligand-independent EphA2 signaling drives an amoeboid phenotype that promotes melanoma brain metastasis development von Zhang, Chao, Smalley, Inna, Sharma, Ritin, Emmons, Michael, Messina, Jane, Koomen, John, Smalley, Keiran

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Phase 1B study of avelumab and whole brain radiotherapy (WBRT) in patients with leptomeningeal disease (LMD) from epithelial carcinomas: Final results and molecular analyses with s... von Pina, Yolanda, Chen, Ann, Arrington, John, Macaulay, Robert J, Tran, Nam D., Liu, James K, Mokhtari, Sepideh, Li, Jiannong, Law, Vincent, Sahebjam, Solmaz, Ahmed, Kamran A., Creelan, Ben C., Gray, Jhanelle Elaine, Evernden, Brittany, Khushalani, Nikhil I., Smalley, Inna, Vogelbaum, Michael A., Yu, Michael, Smalley, Keiran, Forsyth, Peter A. J.

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BIOM-02. LEPTOMENINGEAL DISEASE SECONDARY TO MELANOMA: UPDATES ON THE VALIDITY OF THE VERIDEX CELLSEARCH SYSTEM von Pina, yolanda, Mokhtari, Sepideh, Kim, Youngchul, Evernden, Brittany, Tran, Nam, Smalley, Inna, Khushalani, Nikhil, Law, Vincent, Puskas, John, Caseres, Gisela, Vogelbaum, Michael, Smalley, Keiran, Peguero, Edwin, Forsyth, Peter

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