Clinical and Pathologic Features of Familial Pancreatic Cancer von HUMPHRIS, Jeremy L, JOHNS, Amber L, SCOTT MEAD, R, GILL, Anthony J, SAMRA, Jaswinder S, KENCH, James G, MUSGROVE, Elizabeth A, TUCKER, Katherine M, SPIGELMAN, Allan D, WADDELL, Nic, GRIMMOND, Sean M, BIANKIN, Andrew V, SIMPSON, Skye H, COWLEY, Mark J, PAJIC, Marina, CHANG, David K, NAGRIAL, Adnan M, CHIN, Venessa T, CHANTRILL, Lorraine A, PINESE, Mark

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Targeting the undruggable in pancreatic cancer using nano-based gene silencing drugs von Kokkinos, John, Ignacio, Rosa Mistica C., Sharbeen, George, Boyer, Cyrille, Gonzales-Aloy, Estrella, Goldstein, David, Australian Pancreatic Cancer Genome Initiative (APGI), McCarroll, Joshua A., Phillips, Phoebe A.

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Gemcitabine and CHK1 Inhibition Potentiate EGFR-Directed Radioimmunotherapy against Pancreatic Ductal Adenocarcinoma von AL-EJEH, Fares, PAJIC, Marina, KUM KUM KHANNA, WEI SHI, KALIMUTHO, Murugan, MIRANDA, Mariska, NAGRIAL, Adnan M, CHOU, Angela, BIANKIN, Andrew V, GRIMMOND, Sean M, BROWN, Michael P

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Genomic analyses identify molecular subtypes of pancreatic cancer von Bailey, Peter, Chang, David K., Nones, Katia, Johns, Amber L., Patch, Ann-Marie, Gingras, Marie-Claude, Miller, David K., Christ, Angelika N., Bruxner, Tim J. C., Quinn, Michael C., Nourse, Craig, Murtaugh, L. Charles, Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourbakhsh, Ehsan, Wani, Shivangi, Fink, Lynn, Holmes, Oliver, Chin, Venessa, Anderson, Matthew J., Kazakoff, Stephen, Leonard, Conrad, Newell, Felicity, Waddell, Nick, Wood, Scott, Xu, Qinying, Wilson, Peter J., Cloonan, Nicole, Kassahn, Karin S., Taylor, Darrin, Quek, Kelly, Robertson, Alan, Pantano, Lorena, Mincarelli, Laura, Sanchez, Luis N., Evers, Lisa, Wu, Jianmin, Pinese, Mark, Cowley, Mark J., Jones, Marc D., Colvin, Emily K., Nagrial, Adnan M., Humphrey, Emily S., Chantrill, Lorraine A., Mawson, Amanda, Humphris, Jeremy, Chou, Angela, Pajic, Marina, Scarlett, Christopher J., Pinho, Andreia V., Giry-Laterriere, Marc, Rooman, Ilse, Samra, Jaswinder S., Kench, James G., Lovell, Jessica A., Merrett, Neil D., Toon, Christopher W., Epari, Krishna, Nguyen, Nam Q., Barbour, Andrew, Zeps, Nikolajs, Moran-Jones, Kim, Jamieson, Nigel B., Graham, Janet S., Duthie, Fraser, Oien, Karin, Hair, Jane, Grützmann, Robert, Maitra, Anirban, Iacobuzio-Donahue, Christine A., Wolfgang, Christopher L., Morgan, Richard A., Lawlor, Rita T., Corbo, Vincenzo, Bassi, Claudio, Rusev, Borislav, Capelli, Paola, Salvia, Roberto, Tortora, Giampaolo, Mukhopadhyay, Debabrata, Petersen, Gloria M., Munzy, Donna M., Fisher, William E., Karim, Saadia A., Eshleman, James R., Hruban, Ralph H., Pilarsky, Christian, Sansom, Owen J., Scarpa, Aldo, Bailey, Ulla-Maja Hagbo, Hofmann, Oliver, Sutherland, Robert L., Wheeler, David A., Gill, Anthony J., Gibbs, Richard A., Pearson, John V., Waddell, Nicola, Biankin, Andrew V., Grimmond, Sean M.

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Whole-genome landscape of pancreatic neuroendocrine tumours von Scarpa, Aldo, Chang, David K., Nones, Katia, Corbo, Vincenzo, Patch, Ann-Marie, Bailey, Peter, Lawlor, Rita T., Johns, Amber L., Miller, David K., Mafficini, Andrea, Rusev, Borislav, Scardoni, Maria, Antonello, Davide, Barbi, Stefano, Sikora, Katarzyna O., Cingarlini, Sara, Vicentini, Caterina, McKay, Skye, Quinn, Michael C. J., Bruxner, Timothy J. C., Christ, Angelika N., Harliwong, Ivon, Idrisoglu, Senel, McLean, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wilson, Peter J., Anderson, Matthew J., Fink, J. Lynn, Newell, Felicity, Waddell, Nick, Holmes, Oliver, Kazakoff, Stephen H., Leonard, Conrad, Wood, Scott, Xu, Qinying, Nagaraj, Shivashankar Hiriyur, Amato, Eliana, Dalai, Irene, Bersani, Samantha, Cataldo, Ivana, Dei Tos, Angelo P., Capelli, Paola, Davì, Maria Vittoria, Landoni, Luca, Malpaga, Anna, Miotto, Marco, Whitehall, Vicki L. J., Leggett, Barbara A., Harris, Janelle L., Harris, Jonathan, Jones, Marc D., Humphris, Jeremy, Chantrill, Lorraine A., Chin, Venessa, Nagrial, Adnan M., Pajic, Marina, Scarlett, Christopher J., Rooman, Ilse, Toon, Christopher, Wu, Jianmin, Pinese, Mark, Barbour, Andrew, Mawson, Amanda, Humphrey, Emily S., Colvin, Emily K., Chou, Angela, Lovell, Jessica A., Jamieson, Nigel B., Duthie, Fraser, Gingras, Marie-Claude, Fisher, William E., Dagg, Rebecca A., Lau, Loretta M. S., Lee, Michael, Pickett, Hilda A., Reddel, Roger R., Samra, Jaswinder S., Merrett, Neil D., Epari, Krishna, Nguyen, Nam Q., Zeps, Nikolajs, Falconi, Massimo, Simbolo, Michele, Butturini, Giovanni, Van Buren, George, Partelli, Stefano, Fassan, Matteo, Khanna, Kum Kum, Gill, Anthony J., Wheeler, David A., Gibbs, Richard A., Musgrove, Elizabeth A., Bassi, Claudio, Tortora, Giampaolo, Pederzoli, Paolo, Pearson, John V., Waddell, Nicola, Biankin, Andrew V., Grimmond, Sean M.

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Whole genomes redefine the mutational landscape of pancreatic cancer von Waddell, Nicola, Pajic, Marina, Patch, Ann-Marie, Chang, David K., Kassahn, Karin S., Bailey, Peter, Johns, Amber L., Miller, David, Nones, Katia, Quek, Kelly, Quinn, Michael C. J., Robertson, Alan J., Fadlullah, Muhammad Z. H., Bruxner, Tim J. C., Christ, Angelika N., Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wani, Shivangi, Wilson, Peter J., Markham, Emma, Cloonan, Nicole, Anderson, Matthew J., Fink, J. Lynn, Holmes, Oliver, Kazakoff, Stephen H., Leonard, Conrad, Newell, Felicity, Poudel, Barsha, Song, Sarah, Taylor, Darrin, Waddell, Nick, Wood, Scott, Xu, Qinying, Wu, Jianmin, Pinese, Mark, Cowley, Mark J., Lee, Hong C., Jones, Marc D., Nagrial, Adnan M., Humphris, Jeremy, Chantrill, Lorraine A., Chin, Venessa, Steinmann, Angela M., Mawson, Amanda, Humphrey, Emily S., Colvin, Emily K., Chou, Angela, Scarlett, Christopher J., Pinho, Andreia V., Giry-Laterriere, Marc, Rooman, Ilse, Samra, Jaswinder S., Kench, James G., Pettitt, Jessica A., Merrett, Neil D., Toon, Christopher, Epari, Krishna, Nguyen, Nam Q., Barbour, Andrew, Zeps, Nikolajs, Jamieson, Nigel B., Graham, Janet S., Niclou, Simone P., Bjerkvig, Rolf, Grützmann, Robert, Aust, Daniela, Hruban, Ralph H., Maitra, Anirban, Iacobuzio-Donahue, Christine A., Wolfgang, Christopher L., Morgan, Richard A., Lawlor, Rita T., Corbo, Vincenzo, Bassi, Claudio, Falconi, Massimo, Zamboni, Giuseppe, Tortora, Giampaolo, Tempero, Margaret A., Gill, Anthony J., Eshleman, James R., Pilarsky, Christian, Scarpa, Aldo, Musgrove, Elizabeth A., Pearson, John V., Biankin, Andrew V., Grimmond, Sean M.

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Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition von Sharbeen, George, McCarroll, Joshua A., Akerman, Anouschka, Kopecky, Chantal, Youkhana, Janet, Kokkinos, John, Holst, Jeff, Boyer, Cyrille, Erkan, Mert, Goldstein, David, Timpson, Paul, Cox, Thomas R., Pereira, Brooke A., Chitty, Jessica L., Fey, Sigrid K., Najumudeen, Arafath K., Campbell, Andrew D., Sansom, Owen J., Ignacio, Rosa Mistica C., Naim, Stephanie, Liu, Jie, Russia, Nelson, Lee, Julia, Chou, Angela, Johns, Amber, Gill, Anthony J., Gonzales-Aloy, Estrella, Gebski, Val, Guan, Yi Fang, Pajic, Marina, Turner, Nigel, Apte, Minoti, Davis, Thomas P., Morton, Jennifer P., Haghighi, Koroush S., Kasparian, Jorjina, McLean, Benjamin J., Setargew, Yordanos F., Phillips, Phoebe A.

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Hypermutation In Pancreatic Cancer von Humphris, Jeremy L, Patch, Ann-Marie, Nones, Katia, Bailey, Peter J, Johns, Amber L, McKay, Skye, Chang, David K, Miller, David K, Pajic, Marina, Kassahn, Karin S, Quinn, Michael C.J, Bruxner, Timothy J.C, Christ, Angelika N, Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Stone, Andrew, Wilson, Peter J, Anderson, Matthew, Fink, J. Lynn, Holmes, Oliver, Kazakoff, Stephen, Leonard, Conrad, Newell, Felicity, Waddell, Nick, Wood, Scott, Mead, Ronald S, Xu, Qinying, Wu, Jianmin, Pinese, Mark, Cowley, Mark J, Jones, Marc D, Nagrial, Adnan M, Chin, Venessa T, Chantrill, Lorraine A, Mawson, Amanda, Chou, Angela, Scarlett, Christopher J, Pinho, Andreia V, Rooman, Ilse, Giry-Laterriere, Marc, Samra, Jaswinder S, Kench, James G, Merrett, Neil D, Toon, Christopher W, Epari, Krishna, Nguyen, Nam Q, Barbour, Andrew, Zeps, Nikolajs, Jamieson, Nigel B, McKay, Colin J, Carter, C. Ross, Dickson, Euan J, Graham, Janet S, Duthie, Fraser, Oien, Karin, Hair, Jane, Morton, Jennifer P, Sansom, Owen J, Grützmann, Robert, Hruban, Ralph H, Maitra, Anirban, Iacobuzio-Donahue, Christine A, Schulick, Richard D, Wolfgang, Christopher L, Morgan, Richard A, Lawlor, Rita T, Rusev, Borislav, Corbo, Vincenzo, Salvia, Roberto, Cataldo, Ivana, Tortora, Giampaolo, Tempero, Margaret A, Hofmann, Oliver, Eshleman, James R, Pilarsky, Christian, Scarpa, Aldo, Musgrove, Elizabeth A, Gill, Anthony J, Pearson, John V, Grimmond, Sean M, Waddell, Nicola, Biankin, Andrew V

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Fibroblast Activation Protein Is Overexpressed on Both Stromal and Epithelial Cells Before Pancreatic Ductal Adenocarcinoma: Implications for Early Diagnosis on 68Ga-FAPI-PET/CT von McGahan, William, Gough, Madeline, Liu, Cheng, Hoyte, Sharon, Gill, Anthony J., Cavallucci, David, Cooper, Caroline, Butler, Nick, Yeung, Shinn, Kryza, Thomas, Gulhane, Brook, Latter, Melissa J., Waddell, Nicola, Samra, Jaswinder S., Simpson, Fiona, Pajic, Marina, Thomas, Paul A., O’Rourke, Thomas, Hooper, John D.

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Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer von Chou, Angela, Froio, Danielle, Nagrial, Adnan M, Parkin, Ashleigh, Murphy, Kendelle J, Chin, Venessa T, Wohl, Dalia, Steinmann, Angela, Stark, Rhys, Drury, Alison, Walters, Stacey N, Vennin, Claire, Burgess, Andrew, Pinese, Mark, Chantrill, Lorraine A, Cowley, Mark J, Molloy, Timothy J, Waddell, Nicola, Johns, Amber, Grimmond, Sean M, Chang, David K, Biankin, Andrew V, Sansom, Owen J, Morton, Jennifer P, Grey, Shane T, Cox, Thomas R, Turchini, John, Samra, Jaswinder, Clarke, Stephen J, Timpson, Paul, Gill, Anthony J, Pajic, Marina

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The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma von Pérez-Mancera, Pedro A., Rust, Alistair G., van der Weyden, Louise, Kristiansen, Glen, Li, Allen, Sarver, Aaron L., Silverstein, Kevin A. T., Grützmann, Robert, Aust, Daniela, Rümmele, Petra, Knösel, Thomas, Herd, Colin, Stemple, Derek L., Kettleborough, Ross, Brosnan, Jacqueline A., Li, Ang, Morgan, Richard, Knight, Spencer, Yu, Jun, Stegeman, Shane, Collier, Lara S., ten Hoeve, Jelle J., de Ridder, Jeroen, Klein, Alison P., Goggins, Michael, Hruban, Ralph H., Chang, David K., Biankin, Andrew V., Grimmond, Sean M., Wessels, Lodewyk F. A., Wood, Stephen A., Iacobuzio-Donahue, Christine A., Pilarsky, Christian, Largaespada, David A., Adams, David J., Tuveson, David A.

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Defining the molecular pathology of pancreatic body and tail adenocarcinoma von Dreyer, S. B., Jamieson, N. B., Upstill‐Goddard, R., Bailey, P. J., McKay, C. J., Biankin, A. V., Chang, D. K.

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SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer von Harris, N L E, Vennin, C, Conway, J R W, Vine, K L, Pinese, M, Cowley, M J, Shearer, R F, Lucas, M C, Herrmann, D, Allam, A H, Pajic, M, Morton, J P, Biankin, A V, Ranson, M, Timpson, P, Saunders, D N

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Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma von Mann, Karen M., Ward, Jerrold M., Yew, Christopher Chin Kuan, Kovochich, Anne, Dawson, David W., Black, Michael A., Brett, Benjamin T., Sheetz, Todd E., Dupuy, Adam J., Chang, David K., Biankin, Andrew V., Waddell, Nicola, Kassahn, Karin S., Grimmond, Sean M., Rust, Alistair G., Adams, David J., Jenkins, Nancy A., Copeland, Neal G.

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Signatures of mutational processes in human cancer von Alexandrov, Ludmil B., Nik-Zainal, Serena, Wedge, David C., Aparicio, Samuel A. J. R., Behjati, Sam, Biankin, Andrew V., Bignell, Graham R., Bolli, Niccolò, Borg, Ake, Børresen-Dale, Anne-Lise, Boyault, Sandrine, Burkhardt, Birgit, Butler, Adam P., Caldas, Carlos, Davies, Helen R., Desmedt, Christine, Eils, Roland, Eyfjörd, Jórunn Erla, Foekens, John A., Greaves, Mel, Hosoda, Fumie, Hutter, Barbara, Ilicic, Tomislav, Imbeaud, Sandrine, Imielinski, Marcin, Jäger, Natalie, Jones, David T. W., Jones, David, Knappskog, Stian, Kool, Marcel, Lakhani, Sunil R., López-Otín, Carlos, Martin, Sancha, Munshi, Nikhil C., Nakamura, Hiromi, Northcott, Paul A., Pajic, Marina, Papaemmanuil, Elli, Paradiso, Angelo, Pearson, John V., Puente, Xose S., Raine, Keiran, Ramakrishna, Manasa, Richardson, Andrea L., Richter, Julia, Rosenstiel, Philip, Schlesner, Matthias, Schumacher, Ton N., Span, Paul N., Teague, Jon W., Totoki, Yasushi, Tutt, Andrew N. J., Valdés-Mas, Rafael, van Buuren, Marit M., van ’t Veer, Laura, Vincent-Salomon, Anne, Waddell, Nicola, Yates, Lucy R., Zucman-Rossi, Jessica, Andrew Futreal, P., McDermott, Ultan, Lichter, Peter, Meyerson, Matthew, Grimmond, Sean M., Siebert, Reiner, Campo, Elías, Shibata, Tatsuhiro, Pfister, Stefan M., Campbell, Peter J., Stratton, Michael R.

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Targeting mTOR dependency in pancreatic cancer von Morran, Douglas C, Wu, Jianmin, Jamieson, Nigel B, Mrowinska, Agata, Kalna, Gabriela, Karim, Saadia A, Au, Amy Y M, Scarlett, Christopher J, Chang, David K, Pajak, Malgorzata Z, Oien, Karin A, McKay, Colin J, Carter, C Ross, Gillen, Gerry, Champion, Sue, Pimlott, Sally L, Anderson, Kurt I, Evans, T R Jeffry, Grimmond, Sean M, Biankin, Andrew V, Sansom, Owen J, Morton, Jennifer P

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Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation von Gingras, Marie-Claude, Covington, Kyle R., Chang, David K., Donehower, Lawrence A., Gill, Anthony J., Ittmann, Michael M., Creighton, Chad J., Johns, Amber L., Shinbrot, Eve, Dewal, Ninad, Fisher, William E., Pilarsky, Christian, Grützmann, Robert, Overman, Michael J., Jamieson, Nigel B., Van Buren, George, Drummond, Jennifer, Walker, Kimberly, Hampton, Oliver A., Xi, Liu, Muzny, Donna M., Doddapaneni, Harsha, Lee, Sandra L., Bellair, Michelle, Hu, Jianhong, Han, Yi, Dinh, Huyen H., Dahdouli, Mike, Samra, Jaswinder S., Bailey, Peter, Waddell, Nicola, Pearson, John V., Harliwong, Ivon, Wang, Huamin, Aust, Daniela, Oien, Karin A., Hruban, Ralph H., Hodges, Sally E., McElhany, Amy, Saengboonmee, Charupong, Duthie, Fraser R., Grimmond, Sean M., Biankin, Andrew V., Wheeler, David A., Gibbs, Richard A.

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Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer von Dreyer, Stephan B., Upstill-Goddard, Rosie, Paulus-Hock, Viola, Paris, Clara, Dray, Eloise, Serrels, Bryan, Caligiuri, Giuseppina, Caligiuri, Giuseppina, Rebus, Selma, Plenker, Dennis, Brunton, Holly, Wright, Derek W., McKay, Colin J., Gulati, Aditi, Pettitt, Stephan, Bailey, Peter J., Chang, David K., Cooke, Susanna L., Dreyer, Stephan, Kelly, Shane, Marshall, John, McDade, Brian, Nourse, Craig, Paulus-Hock, Viola, Westwood, Paul, Biankin, Andrew V., Brancato, Mary-Anne L., Chin, Venessa T., Cowley, Mark J., Mead, R. Scott, Nagrial, Adnan M., Pettit, Jessica, Pinese, Mark, Rooman, Ilse, Tao, Jiang, DiPietro, Renee, Watson, Clare, Wong, Rachel, Giry-Laterriere, Marc, Grimmond, Sean M., Waddell, Nicola, Kassahn, Karin S., Patch, Ann-Marie, Idrisoglu, Senel, Nourbakhsh, Ehsan, Wani, Shivangi, Taylor, Darrin, Wood, Scott, Fink, J. Lynn, Bruxner, Tim, Cloonan, Nicole, Newell, Felicity, Pearson, John V., Bailey, Peter, Kazakoff, Stephen, Samra, Jaswinder S., Gill, Anthony J., Pavlakis, Nick, Asghari, Ray, Merrett, Neil D., Cosman, Peter H., Ismail, Kasim, McLeod, Duncan, James, Virginia, Kench, James G., Cooper, Caroline L., Sandroussi, Charbel, Gallagher, James, Texler, Michael, Forest, Cindy, Ballal, Mo, DeBoer, Bastiaan, Chai, Ming, Worthley, Chris, Tan, Chuan P., Martin, Patrick, Chiang, Amy, Yeung, Shinn, Hatzifotis, Michael, Christophi, Christopher, Biobank, Victorian Cancer, Hruban, Ralph H., Iacobuzio-Donahue, Christine A., Schulick, Richard D., Morgan, Richard A., Hodgin, Mary, Scarpa, Aldo, Lawlor, Rita T., Biankin, Andrew V., Grimmond, Sean M., Nourse, Craig, Johns, Amber, Pajic, Marina, Frame, Margaret C., Crawford, Howard C., Pilarsky, Christian, Morton, Jennifer P., Sansom, Owen J., Bailey, Peter J., Chang, David K.

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Precision Oncology in Surgery: Patient Selection for Operable Pancreatic Cancer von Dreyer, Stephan B., Pinese, Mark, Jamieson, Nigel B., Scarlett, Christopher J., Colvin, Emily K., Pajic, Marina, Johns, Amber L., Humphris, Jeremy L., Wu, Jianmin, Cowley, Mark J., Chou, Angela, Nagrial, Adnan M., Chantrill, Lorraine, Chin, Venessa T., Jones, Marc D., Moran-Jones, Kim, Carter, Christopher Ross, Dickson, Euan J., Samra, Jaswinder S., Merrett, Neil D., Gill, Anthony J., Kench, James G., Duthie, Fraser, Miller, David K., Cooke, Susanna, Aust, Daniela, Knösel, Thomas, Rümmele, Petra, Grützmann, Robert, Pilarsky, Christian, Nguyen, Nam Q., Musgrove, Elizabeth A., Bailey, Peter J., McKay, Colin J., Biankin, Andrew V., Chang, David K.

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MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma von Castillo, Lesley, Young, Adelaide I. J., Mawson, Amanda, Schafranek, Pia, Steinmann, Angela M., Nessem, Danielle, Parkin, Ashleigh, Johns, Amber, Chou, Angela, Law, Andrew M. K., Lucas, Morghan C., Murphy, Kendelle J., Deng, Niantao, Gallego-Ortega, David, Caldon, Catherine E., Timpson, Paul, Pajic, Marina, Ormandy, Christopher J., Oakes, Samantha R.

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