Chronic and Acute Alcohol Exposure Prevents Monocyte-Derived Dendritic Cells from Differentiating and Maturing von Buttari, B., Profumo, E., Mancinelli, R., Incani, U. Cesta, Tosti, M.E., Attilia, M.L., Ceccanti, M., Riganò, R.

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Tumor-stroma interactions as a determinant of drug resistance in BRAF-mut melanoma von Falcone, I., Loria, R., Cesta Incani, U., Ciuffreda, L., Bazzichetto, C., Conciatori, F., Bellei, B., Kovacs, D., Picardo, M., Falcioni, R., Milella, M.

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Therapeutic Targeting of Raf-Induced Paradoxical Erk Activation with a Vertical Combination Hitting Multiple Steps Along the Mapk Cascade von Cesta Incani, U., Del Curatolo, A., Falcone, I., Eramo, A., Sette, G., Sperduti, I., Matteoni, S., Shirasawa, S., Broggini, M., De Maria, R., Cognetti, F., Ciuffreda, L., Milella, M.

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1580PTHERAPEUTIC TARGETING OF RAF-INDUCED PARADOXICAL ERK ACTIVATION WITH A VERTICAL COMBINATION HITTING MULTIPLE STEPS ALONG THE MAPK CASCADE von Cesta Incani, U., Del Curatolo, A., Falcone, I., Eramo, A., Sette, G., Sperduti, I., Matteoni, S., Shirasawa, S., Broggini, M., De Maria, R., Cognetti, F., Ciuffreda, L., Milella, M.

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Synergistic Growth Inhibitory Activity of Combined Mek/Mtor Pathway Blockade in Pten-Null Cancers von Ciuffreda, L., Falcone, I., Benfante, A., Matteoni, S., Eramo, A., Sette, G., De Luca, T., Sacconi, A., Malusa, F., Cesta Incani, U., Del Curatolo, A., Konopleva, M., Andreeff, M., Del Bufalo, D., Cognetti, F., De Maria, R., Todaro, M., Stassi, G., Milella, M.

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1578PSYNERGISTIC GROWTH INHIBITORY ACTIVITY OF COMBINED MEK/MTOR PATHWAY BLOCKADE IN PTEN-NULL CANCERS von Ciuffreda, L., Falcone, I., Benfante, A., Matteoni, S., Eramo, A., Sette, G., De Luca, T., Sacconi, A., Malusa, F., Cesta Incani, U., Del Curatolo, A., Konopleva, M., Andreeff, M., Del Bufalo, D., Cognetti, F., De Maria, R., Todaro, M., Stassi, G., Milella, M.

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1156 POSTER Synergistic Activity of ‘Vertical’ Combinations of Agents Targeting the RAF/MEK/ERK Cascade as a Therapeutic Strategy in Human Tumours von Incani, U. Cesta, Ciuffreda, L, Falcone, I, Cognetti, F, Milella, M

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1155 POSTER Synergistic Interaction Between MEK and MTor Inhibitors in Cancer Cells With PTEN Loss von Ciuffreda, L, Falcone, I, Incani, U. Cesta, Cognetti, F, Milella, M

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Effect of a novel cross-talk mechanism on the RAF/MEK/ERK and PI3K/AKT/mTOR pathways in melanoma: Role of ERK-mediated suppression of PTEN expression von Ciuffreda, L., Di Sanza, C., Desideri, M., Ricciardi, M., Cesta Incani, U., Tafuri, A., Cognetti, F., Zupi, G., Del Bufalo, D., Milella, M.

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