Topic: AS04-MDS Biology and Pathogenesis/AS04f-Gene expression profiling: CMML PATIENTS WITH LOW EXPRESSION OF TP53 POINT TO AML TRANSFORMATION von Imanci, A., Laplane, L., Selimoglu-Buet, D., Morabito, M., Francillette, M., Bouchra, B., Wagner-Ballon, O., Thépot, S., Porteu, F., Fenaux, P., Figueroa, M., Itzykson, R., Solary, E., Droin, N.

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Topic: AS04-MDS Biology and Pathogenesis/AS04h-Immune deregulation/inflammation: CXCL8 SECRETED BY IMMATURE GRANULOCYTES INHIBITS WILD-TYPE STEM AND PROGENITOR CELL EXPANSION IN CH... von Deschamps, P., Gosseye, A., Morabito, M., Imanci, A., Marchand, V., Patnaik, M., Badaoui, B., Braun, T., Berthon, C., Willekens, C., Itzykson, R., Wagner-Ballon, O., Thépot, S., Fenaux, P., Porteu, F., Droin, N., Laplane, L., Solary, E., Selimoglu-Buet, D.

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A genome-scale map of DNA methylation turnover identifies site-specific dependencies of DNMT and TET activity von Ginno, Paul Adrian, Gaidatzis, Dimos, Feldmann, Angelika, Hoerner, Leslie, Imanci, Dilek, Burger, Lukas, Zilbermann, Frederic, Peters, Antoine H. F. M., Edenhofer, Frank, Smallwood, Sébastien A., Krebs, Arnaud R., Schübeler, Dirk

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Dynamic gene regulation by nuclear colony-stimulating factor 1 receptor in human monocytes and macrophages von Bencheikh, Laura, Diop, M’Boyba Khadija, Rivière, Julie, Imanci, Aygun, Pierron, Gerard, Souquere, Sylvie, Naimo, Audrey, Morabito, Margot, Dussiot, Michaël, De Leeuw, Frédéric, Lobry, Camille, Solary, Eric, Droin, Nathalie

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Genome-wide Single-Molecule Footprinting Reveals High RNA Polymerase II Turnover at Paused Promoters von Krebs, Arnaud R., Imanci, Dilek, Hoerner, Leslie, Gaidatzis, Dimos, Burger, Lukas, Schübeler, Dirk

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Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model von Arkoun, Brahim, Robert, Elie, Boudia, Fabien, Mazzi, Stefania, Dufour, Virginie, Siret, Aurélie, Mammasse, Yasmine, Aid, Zakia, Vieira, Matthieu, Imanci, Aygun, Aglave, Marine, Cambot, Marie, Petermann, Rachel, Souquere, Sylvie, Rameau, Philippe, Catelain, Cyril, Diot, Romain, Tachdjian, Gérard, Hermine, Olivier, Droin, Nathalie, Debili, Najet, Plo, Isabelle, Malinge, Sébastien, Soler, Eric, Raslova, Hana, Mercher, Thomas, Vainchenker, William

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Molecular Co-occupancy Identifies Transcription Factor Binding Cooperativity In Vivo von Sönmezer, Can, Kleinendorst, Rozemarijn, Imanci, Dilek, Barzaghi, Guido, Villacorta, Laura, Schübeler, Dirk, Benes, Vladimir, Molina, Nacho, Krebs, Arnaud Regis

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ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation von Sun, Tianliang, Annunziato, Stefano, Bergling, Sebastian, Sheng, Caibin, Orsini, Vanessa, Forcella, Pascal, Pikiolek, Monika, Kancherla, Venkatesh, Holwerda, Sjoerd, Imanci, Dilek, Wu, Fabian, Meylan, Ludivine Challet, Puehringer, Lea F., Waldt, Annick, Oertli, Mevion, Schuierer, Sven, Terracciano, Luigi M., Reinker, Stefan, Ruffner, Heinz, Bouwmeester, Tewis, Sailer, Andreas W., George, Elizabeth, Roma, Guglielmo, de Weck, Antoine, Piscuoglio, Salvatore, Lohmann, Felix, Naumann, Ulrike, Liberali, Prisca, Cong, Feng, Tchorz, Jan S.

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New MCM8 mutation associated with premature ovarian insufficiency and chromosomal instability in a highly consanguineous Tunisian family von Bouali, Nouha, Francou, Bruno, Bouligand, Jérôme, Imanci, Dilek, Dimassi, Sarra, Tosca, Lucie, Zaouali, Monia, Mougou, Soumaya, Young, Jacques, Saad, Ali, Guiochon-Mantel, Anne

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Long-lasting successful dissemination of resistance to oxazolidinones in MDR Staphylococcus epidermidis clinical isolates in a tertiary care hospital in France von Dortet, Laurent, Glaser, Philippe, Kassis-Chikhani, Najiby, Girlich, Delphine, Ichai, Philippe, Boudon, Marc, Samuel, Didier, Creton, Elodie, Imanci, Dilek, Bonnin, Rémy, Fortineau, Nicolas, Naas, Thierry

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Structural Variation Cooperates with Permissive Chromatin to Control Enhancer Hijacking-Mediated Oncogenic Transcription von Botten, Giovanni A., Zhang, Yuannyu, Dudnyk, Kseniia, Liu, Xin, Sanders, Jacob T., Imanci, Aygun, Droin, Nathalie, Cao, Hui, Kaphle, Pranita, Dickerson, Kathryn E., Chen, Mingyi, Chen, Weina, Solary, Eric, Ly, Peter, Zhou, Jian, Xu, Jian

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Targeting heterochromatin eliminates chronic myelomonocytic leukemia malignant stem cells through reactivation of retroelements and immune pathways von Hidaoui, Donia, Porquet, Audrey, Chelbi, Rabie, Bohm, Mathieu, Polyzou, Aikaterini, Alcazer, Vincent, Depil, Stéphane, Imanci, Aygun, Morabito, Margot, Renneville, Aline, Selimoglu-Buet, Dorothée, Thépot, Sylvain, Itzykson, Raphael, Laplane, Lucie, Droin, Nathalie, Trompouki, Eirini, Elvira-Matelot, Emilie, Solary, Eric, Porteu, Françoise

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Structural variation cooperates with permissive chromatin to control enhancer hijacking–mediated oncogenic transcription von Botten, Giovanni A., Zhang, Yuannyu, Dudnyk, Kseniia, Kim, Yoon Jung, Liu, Xin, Sanders, Jacob T., Imanci, Aygun, Droin, Nathalie, Cao, Hui, Kaphle, Pranita, Dickerson, Kathryn E., Kumar, Kirthi R., Chen, Mingyi, Chen, Weina, Solary, Eric, Ly, Peter, Zhou, Jian, Xu, Jian

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CXCL8 secreted by immature granulocytes inhibits WT hematopoiesis in chronic myelomonocytic leukemia von Deschamps, Paul, Wacheux, Margaux, Gosseye, Axel, Morabito, Margot, Pagès, Arnaud, Lyne, Anne-Marie, Alfaro, Alexia, Rameau, Philippe, Imanci, Aygun, Chelbi, Rabie, Marchand, Valentine, Renneville, Aline, Patnaik, Mrinal M., Lapierre, Valerie, Badaoui, Bouchra, Wagner-Ballon, Orianne, Berthon, Céline, Braun, Thorsten, Willekens, Christophe, Itzykson, Raphael, Fenaux, Pierre, Thépot, Sylvain, Etienne, Gabriel, Elvira-Matelot, Emilie, Porteu, Francoise, Droin, Nathalie, Perié, Leïla, Laplane, Lucie, Solary, Eric, Selimoglu-Buet, Dorothée

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Fructose 1,6-bisphosphatase deficiency: clinical, biochemical and genetic features in French patients von Lebigot, Elise, Brassier, Anaïs, Zater, Mokhtar, Imanci, Dilek, Feillet, François, Thérond, Patrice, de Lonlay, Pascale, Boutron, Audrey

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Rôle dynamique de CSF1R nucléaire dans la lignée monocytaire von Bencheikh, Laura, Imanci, Aygun, Plocque, Alexia, Solary, Éric, Droin, Nathalie

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Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model von Arkoun, Brahim, Robert, Elie, Boudia, Fabien, Mazzi, Stefania, Dufour, Virginie, Siret, Aurélie, Mammasse, Yasmine, Aid, Zakia, Vieira, Matthieu, Aygun, Imanci, Aglave, Marine, Cambot, Marie, Petermann, Rachel, Souquere, Sylvie, Rameau, Philippe, Catelain, Cyril, Diot, Romain, Tachdjian, Gérard, Hermine, Olivier, Droin, Nathalie, Debili, Najet, Plo, Isabelle, Malinge, Sébastien, Soler, Eric, Raslova, Hana, Mercher, Thomas, Vainchenker, William

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First Occurrence of OXA-72-Producing Acinetobacter baumannii in Serbia von Dortet, Laurent, Bonnin, Rémy A, Bernabeu, Sandrine, Escaut, Lélia, Vittecoq, Daniel, Girlich, Delphine, Imanci, Dilek, Fortineau, Nicolas, Naas, Thierry

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Macrophage migration inhibitory factor is overproduced through EGR1 in TET2low resting monocytes von Pronier, Elodie, Imanci, Aygun, Selimoglu-Buet, Dorothée, Badaoui, Bouchra, Itzykson, Raphael, Roger, Thierry, Jego, Chloé, Naimo, Audrey, Francillette, Maëla, Breckler, Marie, Wagner-Ballon, Orianne, Figueroa, Maria E., Aglave, Marine, Gautheret, Daniel, Porteu, Françoise, Bernard, Olivier A., Vainchenker, William, Delhommeau, François, Solary, Eric, Droin, Nathalie M.

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Long-lasting successful dissemination of resistance to oxazolidinones in MDR Staphylococcus epidermidis clinical isolates in a tertiary care hospital in France von Dortet, L, Glaser, P, Kassis-Chikhani, N, Girlich, D, Ichai, P, Boudon, M, Samuel, D, Creton, E, Imanci, D, Bonnin, R, Fortineau, N, Naas, T

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