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    Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths von Gervais, A, Philippot, Q, Manry, J, Michailidis, E, Parra-Martinez, A, Yang, R, Haljasmagi, L, Migaud, M, Sarekannu, K, Maslovskaja, J, de Prost, N, Tandjaoui-Lambiotte, Y, Poissy, J, Morel, P, Richard, P, Trouillet-Assant, S, Belot, A, Saker, K, Garcon, P, Lagier, JC, Gentile, S, Shaw, E, Morio, T, Tharaux, PL, Sene, D, Stepanian, A, Heath, JR, Franco, JL, Imberti, L, Biondi, A, Bonfanti, P, Castagnoli, R, Zhang, Y, Holland, SM, Biggs, CM, Lorenzo, L, Anglicheau, D, Haerynck, F, Nussbaum, RL, Keles, S, Bousfiha, AA, El Bakkouri, J, Ramirez-Santana, C, Pan-Hammarstrom, Q, Kurolap, A, Lampasona, V, Dominguez-Garrido, E, Vidigal, M, Zatz, M, van de Beek, D, Sahanic, S, Tancevski, I, Boyarchuk, O, Tangye, SG, Burrel, S, Duffy, D, Quintana-Murci, L, Klocperk, A, Shcherbina, A, Lau, YL, Chauvineau-Grenier, A, Venet, F, Monneret, G, Dyer, AH, Bourke, NM, Dorgham, K, Sedkaoui, SM, Rigo-Bonnin, R, Vinh, DC, Ostrowski, SR, Condino-Neto, A, Prando, C, Bondarenko, A, Spaan, AN, Gilardin, L, Fellay, J, Lyonnet, S, Lifton, RP, Mane, S, Anderson, MS, Andreakos, E, Pujol, A, Mogensen, TH, Mond, J, Debette, S, de Lamballerie, X, Gorochov, G, Solanich, X, Susen, S, Raoult, D, Gregersen, PK, Piemonti, L, Rodriguez-Gallego, C, Notarangelo, LD, Kisand, K, Okada, S, Rice, CM, Tiberghien, P, Zhang, Q, Abel, L

    Veröffentlicht in Science immunology

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    Autoantibodies against type I IFNs in patients with life-threatening COVID-19 von Rosen, Lindsey B, Zhang, Qian, Michailidis, Eleftherios, Hoffmann, Hans-Heinrich, Zhang, Yu, Dorgham, Karim, Philippot, Quentin, Rosain, Jérémie, Béziat, Vivien, Shaw, Elana, Haljasmägi, Liis, Peterson, Pärt, Lorenzo, Lazaro, Bizien, Lucy, Trouillet-Assant, Sophie, Dobbs, Kerry, Almeida de Jesus, Adriana, Belot, Alexandre, Tandjaoui-Lambiotte, Yacine, Le Pen, Jérémie, Kerner, Gaspard, Bigio, Benedetta, Seeleuthner, Yoann, Yang, Rui, Bolze, Alexandre, Spaan, András N, Delmonte, Ottavia M, Abers, Michael S, Aiuti, Alessandro, Casari, Giorgio, Lampasona, Vito, Piemonti, Lorenzo, Ciceri, Fabio, Bilguvar, Kaya, Lifton, Richard P, Vasse, Marc, Smadja, David M, Migaud, Mélanie, Hadjadj, Jérome, Terrier, Benjamin, Duffy, Darragh, Quintana-Murci, Lluis, van de Beek, Diederik, Roussel, Lucie, Vinh, Donald C, Haerynck, Filomeen, Dalmau, David, Martínez Picado, Francisco Javier, Brodin, Petter, Nussenzweig, Michel, Boisson-Dupuis, Stephanie, Rodríguez-Gallego, Carlos, Vogt, Guillaume, Mogensen, Trine Hyrup, Oler, Andrew J, Gu, Jingwen, Burbelo, Peter D, Biondi, Andrea, Bettini, Laura Rachele, Bonfanti, Paolo, Rossignol, Patrick, Mayaux, Julien, Rieux-Laucat, Frédéric, Husebye, Eystein, Fusco, Francesca, Ursini, Matilde Valeria, Imberti, Luisa, Sottini, Alessandra, Paghera, Simone, Quiros-Roldan, Eugenia, Rossi, Camillo, Castagnoli, Riccardo, Montagna, Daniela, Licari, Amelia, Marseglia, Gian Luigi, Duval, Xavier, Ghosn, Jade, Tsang, John S, Goldbach-Mansky, Raphaela, Kisand, Kai, Lionakis, Michail S, Puel, Anne, Holland, Steven M, Jouanguy, Emmanuelle, Rice, Charles M, Cobat, Aurélie, Abel, Laurent, Su, Helen C, Casanova, Jean-Laurent, The University of Hong Kong HGID Lab, The University of Hong Kong NIAID-USUHS Immune Response to COVID Group, COVID Clinicians, COVID-STORM Clinicians, Imagine COVID Group, French COVID Cohort Study Group, The Milieu Intérieur Consortium, CoV-Contact Cohort, Amsterdam UMC Covid-19 Biobank, COVID Human Genetic Effort, Universitat Autònoma de Barcelona

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    Autoantibodies against type I IFNs in patients with life-threatening COVID-19 von Rosen, Lindsey, Zhang, Qian, Michailidis, Eleftherios, Hoffmann, Hans-Heinrich, Zhang, Yu, Dorgham, Karim, Philippot, Quentin, Rosain, Jérémie, Béziat, Vivien, Shaw, Elana, Haljasmägi, Liis, Peterson, Pärt, Lorenzo, Lazaro, Bizien, Lucy, Trouillet-Assant, Sophie, Dobbs, Kerry, Almeida de Jesus, Adriana, Belot, Alexandre, Le Pen, Jérémie, Kerner, Gaspard, Bigio, Benedetta, Seeleuthner, Yoann, Yang, Rui, Bolze, Alexandre, Spaan, András, Delmonte, Ottavia M, Abers, Michael S, Aiuti, Alessandro, Casari, Giorgio, Lampasona, Vito, Piemonti, Lorenzo, Ciceri, Fabio, Bilguvar, Kaya, Lifton, Richard P, Vasse, Marc, Smadja, David M, Migaud, Mélanie, Hadjadj, Jérome, Terrier, Benjamin, Duffy, Darragh, Quintana-Murci, Lluis, van de Beek, Diederik, Roussel, Lucie, Vinh, Donald C, Haerynck, Filomeen, Dalmau, David, Martínez Picado, Francisco Javier, Brodin, Petter, Nussenzweig, Michel, Boisson-Dupuis, Stephanie, Rodríguez-Gallego, Carlos, Vogt, Guillaume, Mogensen, Trine Hyrup, Oler, Andrew J, Gu, Jingwen, Burbelo, Peter D, Biondi, Andrea, Bettini, Laura Rachele, Bonfanti, Paolo, Rossignol, Patrick, Mayaux, Julien, Rieux-Laucat, Frédéric, Husebye, Eystein, Fusco, Francesca, Ursini, Matilde Valeria, Imberti, Luisa, Sottini, Alessandra, Paghera, Simone, Quiros-Roldan, Eugenia, Rossi, Camillo, Castagnoli, Riccardo, Montagna, Daniela, Licari, Amelia, Marseglia, Gian Luigi, Duval, Xavier, Ghosn, Jade, Tsang, John S, Goldbach-Mansky, Raphaela, Kisand, Kai, Lionakis, Michail S, Puel, Anne, Holland, Steven, Jouanguy, Emmanuelle, Rice, Charles M, Cobat, Aurélie, Notarangelo, Luigi, Abel, Laurent, Su, Helen C, Casanova, Jean-Laurent, The University of Hong Kong HGID Lab, The University of Hong Kong NIAID-USUHS Immune Response to COVID Group, COVID Clinicians, COVID-STORM Clinicians, Imagine COVID Group, French COVID Cohort Study Group, The Milieu Intérieur Consortium, CoV-Contact Cohort, Amsterdam UMC Covid-19 Biobank, COVID Human Genetic Effort, Universitat Autònoma de Barcelona

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