Autocrine Transforming Growth Factor-β1 Promotes In Vivo Th17 Cell Differentiation von Gutcher, Ilona, Donkor, Moses K., Ma, Qian, Rudensky, Alexander Y., Flavell, Richard A., Li, Ming O.

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Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas von Friedrich, Mirco, Sankowski, Roman, Bunse, Lukas, Kilian, Michael, Green, Edward, Guevara, Carina Ramallo, Pusch, Stefan, Poschet, Gernot, Sanghvi, Khwab, Hahn, Markus, Bunse, Theresa, Muench, Philipp, Gegner, Hagen M., Sonner, Jana K., von Landenberg, Anna, Cichon, Frederik, Aslan, Katrin, Trobisch, Tim, Schirmer, Lucas, Abu-Sammour, Denis, Kessler, Tobias, Ratliff, Miriam, Schrimpf, Daniel, Sahm, Felix, Hopf, Carsten, Heiland, Dieter H., Schnell, Oliver, Beck, Jurgen, Boettcher, Chotima, Fernandez-Zapata, Camila, Priller, Josef, Heiland, Sabine, Gutcher, Ilona, Quintana, Francisco J., von Deimling, Andreas, Wick, Wolfgang, Prinz, Marco, Platten, Michael

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Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System von Prinz, Marco, Schmidt, Hauke, Mildner, Alexander, Knobeloch, Klaus-Peter, Hanisch, Uwe-Karsten, Raasch, Jenni, Merkler, Doron, Detje, Claudia, Gutcher, Ilona, Mages, Jörg, Lang, Roland, Martin, Roland, Gold, Ralf, Becher, Burkhard, Brück, Wolfgang, Kalinke, Ulrich

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APC-derived cytokines and T cell polarization in autoimmune inflammation von Gutcher, Ilona, Becher, Burkhard

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Autoantibody-Mediated Demyelination Depends on Complement Activation but Not Activatory Fc-Receptors von Urich, Eduard, Gutcher, Ilona, Prinz, Marco, Becher, Burkhard

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Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy von Kober, Christina, Roewe, Julian, Schmees, Norbert, Roese, Lars, Roehn, Ulrike, Bader, Benjamin, Stoeckigt, Detlef, Prinz, Florian, Gorjánácz, Mátyás, Roider, Helge Gottfried, Olesch, Catherine, Leder, Gabriele, Irlbacher, Horst, Lesche, Ralf, Lefranc, Julien, Oezcan-Wahlbrink, Mine, Batra, Ankita Sati, Elmadany, Nirmeen, Carretero, Rafael, Sahm, Katharina, Oezen, Iris, Cichon, Frederik, Baumann, Daniel, Sadik, Ahmed, Opitz, Christiane A, Weinmann, Hilmar, Hartung, Ingo V, Kreft, Bertolt, Offringa, Rienk, Platten, Michael, Gutcher, Ilona

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Comparison of Potent Kv1.5 Potassium Channel Inhibitors Reveals the Molecular Basis for Blocking Kinetics and Binding Mode von Strutz-Seebohm, Nathalie, Gutcher, Ilona, Decher, Niels, Steinmeyer, Klaus, Lang, Florian, Seebohm, Guiscard

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Autocrine Transforming Growth Factor- beta 1 Promotes In Vivo Th17 Cell Differentiation von Gutcher, I, Donkor, M K, Ma, Q, Rudensky, A Y, Flavell, R A, Li, MO

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Interleukin 18-independent engagement of interleukin 18 receptor-α is required for autoimmune inflammation von Becher, Burkhard, Gutcher, Ilona, Urich, Eduard, Wolter, Karina, Prinz, Marco

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Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis von Prinz, Marco, Garbe, Folker, Schmidt, Hauke, Mildner, Alexander, Gutcher, Ilona, Wolter, Karina, Piesche, Matthias, Schroers, Roland, Weiss, Elisabeth, Kirschning, Carsten J, Rochford, Christian D P, Brück, Wolfgang, Becher, Burkhard

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Foxp3+ Regulatory T Cells Promote T Helper 17 Cell Development In Vivo through Regulation of Interleukin-2 von Chen, Yi, Haines, Christopher J., Gutcher, Ilona, Hochweller, Kristin, Blumenschein, Wendy M., McClanahan, Terrill, Hämmerling, Günter, Li, Ming O., Cua, Daniel J., McGeachy, Mandy J.

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Abstract 4454: Identification of BAY-218, a potent and selective small-molecule AhR inhibitor, as a new modality to counteract tumor immunosuppression von Schmees, Norbert, Gutcher, Ilona, Roehn, Ulrike, Irlbacher, Horst, Stoeckigt, Detlef, Bader, Benjamin, Kober, Christina, Roese, Lars, Carretero, Rafael, Oezen, Iris, Zorn, Ludiwg, Platten, Michael, Hartung, Ingo Volker, Kreft, Bertolt, Weinmann, Hilmar

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Abstract 1288: Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor von Gutcher, Ilona, Kober, Christina, Roese, Lars, Roewe, Julian, Schmees, Norbert, Prinz, Florian, Gorjanacz, Matyas, Roehn, Ulrike, Bader, Benjamin, Irlbacher, Horst, Stoeckigt, Detlef, Carretero, Rafael, Sahm, Katharina, Oezen, Iris, Weinmann, Hilmar, Hartung, Ingo V., Kreft, Bertolt, Platten, Michael

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Abstract 2778: Discovery and preclinical characterization of BAY 1905254 a novel immune checkpoint inhibitor for cancer immunotherapy targeting the immunoglobulin-like domain conta... von Huetter, Julia, Gritzan, Uwe, Gutcher, Ilona, Golfier, Sven, Doecke, Wolf-Dietrich, Luetke-Eversloh, Merlin Verena, Roider, Helge, Hunter, John, Pow, Andrew, Liang, Spencer, Levine, Zurit, Levy, Ofer, Vaaknin, Ilan, Kreft, Bertolt, Roese, Lars

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Abstract CT276: Preliminary analysis of pharmacokinetic (PK) and target engagement biomarkers from a first in human phase 1 study of immunomodulatory aryl hydrocarbon receptor (AhR... von Papadopoulos, Kyriakos, Cecchini, Michael, Lopez, Juanita S., Jäger, Dirk, Chung, Ki Young, Platten, Michael, Prinz, Florian, Ishii, Yuko, Schaer, David, Gutcher, Ilona, Leder, Gabriele, Pencheva, Radost, Wagener, Thomas, Scheerans, Christian, Zieschang, Carsten, Wagner, Andrea, Stamatelos, Spyros, Dumbrava, Ecaterina

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Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) von Huetter, Julia, Gritzan, Uwe, Gutcher, Ilona, Doecke, Wolf-Dietrich, Luetke-Eversloh, Merlin V, Golfier, Sven, Roider, Helge G, Frisk, Anna-Lena, Hunter, John, Pow, Andrew, Drake, Andrew, Levine, Zurit, Levy, Ofer, Azulay, Meir, Barbiro, Inbal, Cojocaru, Gady, Vaknin, Ilan, Kreft, Bertolt, Roese, Lars

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Characterization of BAY1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) von Huetter, Julia, Gritzan, Uwe, Gutcher, Ilona, Doecke, Wolf-Dietrich, Luetke-Eversloh, Merlin V., Golfier, Sven, Roider, Helge G., Frisk, Anna-Lena, Hunter, John, Pow, Andrew, Drake, Andrew, Levine, Zurit, Levy, Ofer, Azulay, Meir, Barbiro, Inbal, Cojocaru, Gady, Vaknin, Ilan, Kreft, Bertolt, Roese, Lars

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COMBINATION OF AN AHR-INHIBITOR AND AN PD1-INHIBITOR ANTIBODY AND ITS USE IN THE TREATMENT OF CANCER von GUTCHER, Ilona

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COMBINATION OF AN AHR-INHIBITOR AND AN PD1-INHIBITOR ANTIBODY AND ITS USE IN THE TREATMENT OF CANCER von GUTCHER, Ilona

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Combination of an AhR-inhibitor and an PD1-inhibitor antibody and its use in the treatment of cancer von GUTCHER, Ilona

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