The landscape of GPCR signaling in the regulation of epidermal stem cell fate and skin homeostasis von Pedro, M. Pilar, Lund, Katherine, Iglesias‐Bartolome, Ramiro

Volltext

Regulation of Photosensitivity by the Hippo Pathway in Lupus Skin von Hile, Grace A., Coit, Patrick, Xu, Bin, Victory, Amanda M., Gharaee‐Kermani, Mehrnaz, Estadt, Shannon N., Maz, Mitra P., Martens, Jacob W. S., Wasikowski, Rachael, Dobry, Craig, Tsoi, Lam C., Iglesias‐Bartolome, Ramiro, Berthier, Celine C., Billi, Allison C., Gudjonsson, Johann E., Sawalha, Amr H., Kahlenberg, J. Michelle

Volltext

Protein kinase A inhibitor proteins (PKIs) divert GPCR‐Gαs‐cAMP signaling toward EPAC and ERK activation and are involved in tumor growth von Hoy, James J., Salinas Parra, Natalia, Park, Jeannie, Kuhn, Skyler, Iglesias‐Bartolome, Ramiro

Volltext

YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity von Yuan, Yao, Park, Jeannie, Feng, Amber, Awasthi, Parirokh, Wang, Zhiyong, Chen, Qianming, Iglesias-Bartolome, Ramiro

Volltext

Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry von Feng, Xiaodong, Degese, Maria Sol, Iglesias-Bartolome, Ramiro, Vaque, Jose P., Molinolo, Alfredo A., Rodrigues, Murilo, Zaidi, M. Raza, Ksander, Bruce R., Merlino, Glenn, Sodhi, Akrit, Chen, Qianming, Gutkind, J. Silvio

Volltext

mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis von Iglesias-Bartolome, Ramiro, Patel, Vyomesh, Cotrim, Ana, Leelahavanichkul, Kantima, Molinolo, Alfredo A., Mitchell, James B., Gutkind, J. Silvio

Volltext

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor von Martin, Daniel, Degese, Maria S., Vitale-Cross, Lynn, Iglesias-Bartolome, Ramiro, Valera, Juan Luis Callejas, Wang, Zhiyong, Feng, Xiaodong, Yeerna, Huwate, Vadmal, Vachan, Moroishi, Toshiro, Thorne, Rick F., Zaida, Moraima, Siegele, Bradford, Cheong, Sok C., Molinolo, Alfredo A., Samuels, Yardena, Tamayo, Pablo, Guan, Kun Liang, Lippman, Scott M., Lyons, J. Guy, Gutkind, J. Silvio

Volltext

Exploiting the head and neck cancer oncogenome: widespread PI3K-mTOR pathway alterations and novel molecular targets von Iglesias-Bartolome, Ramiro, Martin, Daniel, Gutkind, J Silvio

Volltext

mTOR co-targeting in cetuximab resistance in head and neck cancers harboring PIK3CA and RAS mutations von Wang, Zhiyong, Martin, Daniel, Molinolo, Alfredo A, Patel, Vyomesh, Iglesias-Bartolome, Ramiro, Degese, Maria Sol, Vitale-Cross, Lynn, Chen, Qianming, Gutkind, J Silvio

Volltext

A Genome-wide RNAi Screen Reveals a Trio-Regulated Rho GTPase Circuitry Transducing Mitogenic Signals Initiated by G Protein-Coupled Receptors von Vaqué, Jose P., Dorsam, Robert T., Feng, Xiaodong, Iglesias-Bartolome, Ramiro, Forsthoefel, David J., Chen, Qianming, Debant, Anne, Seeger, Mark A., Ksander, Bruce R., Teramoto, Hidemi, Gutkind, J. Silvio

Volltext

mTOR inhibition prevents rapid-onset of carcinogen-induced malignancies in a novel inducible HPV-16 E6/E7 mouse model von Callejas-Valera, Juan Luis, Iglesias-Bartolome, Ramiro, Amornphimoltham, Panomwat, Palacios-Garcia, Julia, Martin, Daniel, Califano, Joseph A, Molinolo, Alfredo A, Gutkind, J Silvio

Volltext

Policing Tumorigenesis within the Skin: Good Outs Bad von Iglesias-Bartolome, Ramiro, Morasso, Maria I.

Volltext

Genome‐wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy von Sahu, Avinash Das, S Lee, Joo, Wang, Zhiyong, Zhang, Gao, Iglesias‐Bartolome, Ramiro, Tian, Tian, Wei, Zhi, Miao, Benchun, Nair, Nishanth Ulhas, Ponomarova, Olga, Friedman, Adam A, Amzallag, Arnaud, Moll, Tabea, Kasumova, Gyulnara, Greninger, Patricia, Egan, Regina K, Damon, Leah J, Frederick, Dennie T, Jerby‐Arnon, Livnat, Wagner, Allon, Cheng, Kuoyuan, Park, Seung Gu, Robinson, Welles, Gardner, Kevin, Boland, Genevieve, Hannenhalli, Sridhar, Herlyn, Meenhard, Benes, Cyril, Flaherty, Keith, Luo, Ji, Gutkind, J Silvio, Ruppin, Eytan

Volltext

Exploiting the mTOR paradox for disease prevention von Iglesias-Bartolome, Ramiro, Gutkind, J Silvio

Volltext

Fluorescent, Bioactive Protein Nanoparticles (Prodots) for Rapid, Improved Cellular Uptake von Deshapriya, Inoka K, Stromer, Bobbi S, Pattammattel, Ajith, Kim, Christina S, Iglesias-Bartolome, Ramiro, Gonzalez-Fajardo, Laura, Patel, Vyomesh, Gutkind, J. Silvio, Lu, Xiuling, Kumar, Challa V

Volltext

Metabolic pathways and intracellular trafficking of gangliosides von Daniotti, Jose Luis, Iglesias‐Bartolomé, Ramiro

Volltext

Combining portable Raman probes with nanotubes for theranostic applications von Bhirde, Ashwinkumar A, Liu, Gang, Jin, Albert, Iglesias-Bartolome, Ramiro, Sousa, Alioscka A, Leapman, Richard D, Gutkind, J Silvio, Lee, Seulki, Chen, Xiaoyuan

Volltext

A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancers von Yamaguchi, Kosuke, Iglesias-Bartolomé, Ramiro, Wang, Zhiyong, Callejas-Valera, Juan Luis, Amornphimoltham, Panomwat, Molinolo, Alfredo A, Cohen, Ezra E, Califano, Joseph A, Lippman, Scott M, Luo, Ji, Gutkind, J Silvio

Volltext

Targeted delivery of immunotoxin by antibody to ganglioside GD3: a novel drug delivery route for tumor cells von Torres Demichelis, Vanina, Vilcaes, Aldo A, Iglesias-Bartolomé, Ramiro, Ruggiero, Fernando M, Daniotti, Jose L

Volltext

Complex gangliosides are apically sorted in polarized MDCK cells and internalized by clathrin-independent endocytosis von Crespo, Pilar M, von Muhlinen, Natalia, Iglesias-Bartolomé, Ramiro, Daniotti, Jose L

Volltext