Apigenin: Selective CK2 inhibitor increases Ikaros expression and improves T cell homeostasis and function in murine pancreatic cancer von Nelson, Nadine, Szekeres, Karoly, Iclozan, Cristina, Rivera, Ivannie Ortiz, McGill, Andrew, Johnson, Gbemisola, Nwogu, Onyekachi, Ghansah, Tomar

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Anti-inflammatory Triterpenoid Blocks Immune Suppressive Function of MDSCs and Improves Immune Response in Cancer von NAGARAJ, Srinivas, YOUN, Je-In, SPORN, Michael B, LIBY, Karen T, RAWAL, Bhupendra, LEE, Ji-Hyun, GABRILOVICH, Dmitry I, WEBER, Hannah, ICLOZAN, Cristina, LU, Lily, COTTER, Matthew J, MEYER, Colin, BECERRA, Carlos R, FISHMAN, Mayer, ANTONIA, Scott

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Combination of External Beam Radiotherapy (EBRT) With Intratumoral Injection of Dendritic Cells as Neo-Adjuvant Treatment of High-Risk Soft Tissue Sarcoma Patients von Finkelstein, Steven E., M.D, Iclozan, Cristina, Ph.D, Bui, Marilyn M., M.D, Cotter, Matthew J., Ph.D, Ramakrishnan, Rupal, Ph.D, Ahmed, Jamil, B.S, Noyes, David R., Ph.D, Cheong, David, M.D, Gonzalez, Ricardo J., M.D, Heysek, Randy V., M.D, Berman, Claudia, M.D, Lenox, Brianna C., B.S, Janssen, William, Ph.D, Zager, Jonathan S., M.D, Sondak, Vernon K., M.D, Letson, G. Douglas, M.D, Antonia, Scott J., M.D., Ph.D, Gabrilovich, Dmitry I., M.D., Ph.D

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Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer von Iclozan, Cristina, Antonia, Scott, Chiappori, Alberto, Chen, Dung-Tsa, Gabrilovich, Dmitry

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Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells von Hamaidi, Imene, Zhang, Lin, Kim, Nayoung, Wang, Min-Hsuan, Iclozan, Cristina, Fang, Bin, Liu, Min, Koomen, John M., Berglund, Anders E., Yoder, Sean J., Yao, Jiqiang, Engelman, Robert W., Creelan, Ben C., Conejo-Garcia, Jose R., Antonia, Scott J., Mulé, James J., Kim, Sungjune

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Time-course analysis of SHIP-1 modulation and expression in a pancreatic cancer model von McGill, Andrew Robert, Ghansah, Tomar, Ortiz-Rivera, Ivannie, Iclozan, Cristina

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PD-L1/PD-1 Immunotherapy Modulates Effector T Cells Homeostasis and Function in Murine Pancreatic Cancer von Rivera, Ivannie Ortiz, Iclozan, Cristina, McGill, Andrew, Ghansah, Tomar

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CD28 Controls Differentiation of Regulatory T Cells from Naive CD4 T Cells von Guo, Fei, Iclozan, Cristina, Suh, Woong-Kyung, Anasetti, Claudio, Yu, Xue-Zhong

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Abstract 1635: Sirt2 blockade promotes T cell metabolism and restores the anti-tumor immunity von Hamaidi, Imene, Zhang, Lin, Kim, Nayoung, Wang, Min Hsuan, Iclozan, Cristina, Fang, Bin, Liu, Min, Koomen, John M., Berglund, Anders E., Yoder, Sean J., Yao, Jiqiang, Engelman, Robert W., Creelan, Ben C., Conejo-Garcia, Jose R., Mulé, James J., Antonia, Scott J., Kim, Sungjune

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PKCθ is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice von Valenzuela, Javier O, Iclozan, Cristina, Hossain, Mohammad S, Prlic, Martin, Bronk, Crystina C, Wang, Junmei, Celis, Esteban, Engelman, Robert W, Blazar, Bruce R, Bevan, Michael J, Waller, Edmund K, Yu, Xue-Zhong, Beg, Amer A

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IL-7-Dependent Homeostatic Proliferation in the Presence of a Large Number of T Cells in Gld Mice von Aranami, Toshimasa, Iclozan, Cristina, Iwabuchi, Kazuya, Onoé, Kazunori

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Abundant c-Fas–associated death domain–like interleukin-1–converting enzyme inhibitory protein expression determines resistance of T helper 17 cells to activation-induced cell deat... von Yu, Yu, Iclozan, Cristina, Yamazaki, Tomohide, Yang, Xuexian, Anasetti, Claudio, Dong, Chen, Yu, Xue-Zhong

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Analysis of T Cell Responses to a Superantigen, Staphylococcal Enterotoxin-B von Nagashima, Tomomi, Aranami, Toshimasa, Iclozan, Cristina, Onoé, Kazunori

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93 Targeting sirt2 rescues the metabolic fitness and effector functions of tumor-reactive T cells within the metabolically restricted tumor microenvironment von Hamaidi, Imene, Zhang, Lin, Kim, Nayoung, Min-Hsuan Wang, Iclozan, Cristina, Fang, Bin, Liu, Min, Koomen, John, Berglund, Anders, Yoder, Sean, Yao, Jiqiang, Engelman, Robert, Creelan, Ben, Conejo-Garcia, Jose, Scott, Antonia, Mule, James, Kim, Sungjune

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Resistance of Th17 cells to Activation-Induced Cell Death (47.13) von Yu, Xue-Zhong, Iclozan, Cristina, Yang, Xuexian, Anasetti, Claudio, Dong, Chen, Yu, Yu

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CD28 Controls Differentiation of Regulatory T Cells from Naive CD4 T Cells1 von Guo, Fei, Iclozan, Cristina, Suh, Woong-Kyung, Anasetti, Claudio, Yu, Xue-Zhong

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Targeting PKCtheta Inhibits Alloreactivity and Graft-Versus-Host Disease While Preserving Graft-Versus-Leukemia and Anti-Infection Activities von Yu, Xue-Zhong, Valenzuela, Javier, Iclozan, Cristina, Hossain, Mohammad, Hopewell, Emily, Bronk, Crystina, Wang, Junmei, Celis, Esteban, Engelman, Robert, Waller, Edmund K., Blazar, Bruce R., Beg, Amer

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Recent Advances in Immunotherapy of Lung Cancer von Iclozan, Cristina, Gabrilovich, Dmitry I.

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T helper17 Cells Are Sufficient But Not Necessary to Induce Acute Graft-Versus-Host Disease von Iclozan, Cristina, Yu, Yu, Liu, Chen, Liang, Yaming, Yi, Tangsheng, Anasetti, Claudio, Yu, Xue-Zhong

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Anti-inflammatory triterpenoid blocks immune suppressive function of myeloid-derived suppressor cells and improves immune response in cancer von Nagaraj, Srinivas, Youn, Je-In, Weber, Hannah, Iclozan, Cristina, Lu, Lily, Cotter, Matthew J., Meyer, Colin, Becerra, Carlos R., Fishman, Mayer, Antonia, Scott, Sporn, Michael B., Liby, Karen T., Rawal, Bhupendra, Lee, Ji-Hyun, Gabrilovich, Dmitry I.

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