The Role of Myeloperoxidase in Hepatitis C Virus Infection and Associated Liver Cirrhosis von Bekheet, I. W., Madkour, M. E., Ghaffar, N. Abdel, Nosseir, M.M. F., Moussa, M. M., Ibraheim, R. A., Ateya, M. E.

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Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins von Lee, Jooyoung, Mir, Aamir, Edraki, Alireza, Garcia, Bianca, Amrani, Nadia, Lou, Hannah E, Gainetdinov, Ildar, Pawluk, April, Ibraheim, Raed, Gao, Xin D, Liu, Pengpeng, Davidson, Alan R, Maxwell, Karen L, Sontheimer, Erik J

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Modulation Effects of Eugenol on Nephrotoxicity Triggered by Silver Nanoparticles in Adult Rats von Aboelwafa, Hanaa R, Ramadan, Ramadan A, Ibraheim, Somaya S, Yousef, Hany N

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The Ameliorative Role of Eugenol against Silver Nanoparticles-Induced Hepatotoxicity in Male Wistar Rats von Yousef, Hany N., Ibraheim, Somaya S., Ramadan, Ramadan A., Aboelwafa, Hanaa R.

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Exploring the Potential and Limitations of Chat Generative Pre-trained Transformer (ChatGPT) in Generating Board-Style Dermatology Questions: A Qualitative Analysis von Ayub, Ibraheim, Hamann, Dathan, Hamann, Carsten R, Davis, Matthew J

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Immune Checkpoint Inhibitor Therapy in Patients With Preexisting Inflammatory Bowel Disease von Abu-Sbeih, Hamzah, Faleck, David M, Ricciuti, Biagio, Mendelsohn, Robin B, Naqash, Abdul R, Cohen, Justine V, Sellers, Maclean C, Balaji, Aanika, Ben-Betzalel, Guy, Hajir, Ibraheim, Zhang, Jiajia, Awad, Mark M, Leonardi, Giulia C, Johnson, Douglas B, Pinato, David J, Owen, Dwight H, Weiss, Sarah A, Lamberti, Giuseppe, Lythgoe, Mark P, Manuzzi, Lisa, Arnold, Christina, Qiao, Wei, Naidoo, Jarushka, Markel, Gal, Powell, Nick, Yeung, Sai-Ching J, Sharon, Elad, Dougan, Michael, Wang, Yinghong

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Frequency of central nervous system tumors in delta region, Egypt von Zalata, Khaled R, El-Tantawy, Dina A, Abdel-Aziz, Azza, Ibraheim, Abdel-Wahab M, Halaka, Ahmed H, Gawish, Hasan H, Safwat, Mohamed, Mansour, Nabil, Mansour, Mohammad, Shebl, Abdelhadi

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Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and dependent on IL23 and IFNg von Lo, J, Cozzetto, D, Alexander, J, Danckert, N, Madgwick, M, Knox, N, Sieh, J, Olbei, M, Liu, Z, Ibraheim, H, Miguens Blanco, J, Kudo, H, Castro Seoane, R, Possamai, L, Goldin, R, Marchesi, J, Korcsmaros, T, Lord, G, Powell, N

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Adalimumab and Infliximab Impair SARS-CoV-2 Antibody Responses: Results from a Therapeutic Drug Monitoring Study in 11 422 Biologic-Treated Patients von Chanchlani, Neil, Lin, Simeng, Chee, Desmond, Hamilton, Benjamin, Nice, Rachel, Arkir, Zehra, Bewshea, Claire, Cipriano, Bessie, Derikx, Lauranne A A P, Dunlop, Allan, Greathead, Louise, Griffiths, Rachel L, Ibraheim, Hajir, Kelleher, Peter, Kok, Klaartje B, Lees, Charlie W, MacDonald, Jonathan, Sebastian, Shaji, Smith, Philip J, McDonald, Timothy J, Irving, Peter M, Powell, Nick, Kennedy, Nicholas A, Goodhand, James R, Ahmad, Tariq

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Infliximab and Tofacitinib Attenuate Neutralizing Antibody Responses Against SARS-CoV-2 Ancestral and Omicron Variants in Inflammatory Bowel Disease Patients After 3 Doses of COVID... von Liu, Zhigang, Alexander, James L., Lin, Kathy Weitung, Le, Kaixing, Zhou, Xin, Ibraheim, Hajir, Anandabaskaran, Sulak, Saifuddin, Aamir, McFarlane, Leon R., Anand, Nikhil, Constable, Laura, Seoane, Rocio Castro, D’Mello, Andrea, Balarajah, Sharmili, Hicks, Lucy C., Williams, Horace R.T., Lo, Jonathan W., Hart, Ailsa L., Altmann, Daniel M., Boyton, Rosemary J., Teare, Julian P., Nice, Rachel, Bewshea, Claire, Goodhand, James R., Kennedy, Nicholas A., Barnes, Anna, Kirkwood, John, Parkinson, Marian, Gardner-Thorpe, Helen, Lees, Charlie W., Jones, Gareth R., Covil, Kate, Derikx, Lauranne, Fiorentino, Francesca, Irving, Peter M., Parkes, Miles, Linger, Rachel, Kok, Klaartje, Lee, Irish, Cipriano, Bessie, Patel, Kamal V., Sebastian, Shaji, Kent, Alexandra J., Chukwurah, Ijeoma, Haq, Sulaimaan, Shah, Parita, Wilken-Smith, Stephanie, Ramanathan, Anitha, Patel, Mikin, Romanczuk, Lidia, King, Rebecca, Domingo, Jason, Knight, Bridget, Shamtally, Djamila, Mendoza, Vivien, Sanchez, Joanne, Stark, Hannah, Bee, Louise, Estember, Charmaine, Watkins, Darcy, Stone, Sam, Alcalde, Beatriz Gros, Ruocco, Giuseppe, Baden, Manisha, Cooke, Graham, Kourampa, Evgenia, Pasquale, Ciro, Robisco-Diaz, Elena, Bhatti, Suhaylah, Ahmad, Tariq, Pollock, Katrina M., Powell, Nick

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P852 Metataxonomic and metabolomic profiling to predict response to anti-TNF therapy in Crohn’s Disease von Foyzul, J, Alexander, J L, Chappell, K E, Ibraheim, H A, Saifuddin, A, Kennedy, N A, Bewshea, C, Lin, S, Hart, A L, Goodhand, J R, Ahmad, T, Powell, N

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Sleeping Beauty mRNA-LNP enables stable rAAV transgene expression in mouse and NHP hepatocytes and improves vector potency von Zakas, Philip M., Cunningham, Sharon C., Doherty, Ann, van Dijk, Eva B., Ibraheim, Raed, Yu, Stephanie, Mekonnen, Befikadu D., Lang, Brendan, English, Elizabeth J., Sun, Gang, Duncan, Miles C., Benczkowski, Matthew S., Altshuler, Robert C., Singh, Malvenderjit Jagjit, Kibbler, Emily S., Tonga, Gulen Y., Wang, Zi Jun, Wang, Z. Jane, Li, Guangde, An, Ding, Rottman, James B., Bhavsar, Yashvi, Purcell, Cormac, Jain, Rachit, Alberry, Ryan, Roquet, Nathaniel, Fu, Yanfang, Citorik, Robert J., Rubens, Jacob R., Holmes, Michael C., Cotta-Ramusino, Cecilia, Querbes, William, Alexander, Ian E., Salomon, William E.

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The gut microbiota and metabolome are associated with diminished COVID-19 vaccine-induced antibody responses in immunosuppressed inflammatory bowel disease patients von Alexander, James L., Mullish, Benjamin H., Danckert, Nathan P., Liu, Zhigang, Olbei, Marton L., Saifuddin, Aamir, Torkizadeh, Melissa, Ibraheim, Hajir, Blanco, Jesús Miguéns, Roberts, Lauren A., Bewshea, Claire M., Nice, Rachel, Lin, Simeng, Prabhudev, Hemanth, Sands, Caroline, Horneffer-van der Sluis, Verena, Lewis, Matthew, Sebastian, Shaji, Lees, Charlie W., Teare, Julian P., Hart, Ailsa, Goodhand, James R., Kennedy, Nicholas A., Korcsmaros, Tamas, Marchesi, Julian R., Ahmad, Tariq, Powell, Nick

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Theatre efficiency in COVID-19 pandemic conditions: The collaborative experience of four level 1 major trauma centres in the UK von Jeyaseelan, Lucky, Sedgwick, Philip, El-Daly, Ibraheim, Tahmassebi, Ramon, Pearse, Michael, Bhattacharya, Rajarshi, Trompeter, Alex J., Bates, Peter

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Su1485: COVID-19 VACCINE-INDUCED ANTIBODY RESPONSES ARE IMPAIRED IN IBD PATIENTS TREATED WITH INFLIXIMAB, USTEKINUMAB OR TOFACITINIB, BUT NOT THIOPURINES OR VEDOLIZUMAB von Alexander, James L., Kennedy, Nick, Ibraheim, Hajir, Anandabaskaran, Sulak, Saifuddin, Aamir, Seoane, Rocio Castro, Liu, Zhigang, Nice, Rachel, Bewshea, Claire M., D'Mello, Andrea, Constable, Laura E., Jones, Gareth-Rhys, Balarajah, Sharmili, Fiorentino, Francesca, Sebastian, Shaji, Irving, Peter M., Hicks, Lucy C., Williams, Horace R., Kent, Alexandra J., Parkes, Miles, Kok, Klaartje, Patel, Kamal V, Altmann, Daniel, Boyton, Rosemary, Goodhand, James, Hart, Ailsa, Lees, Charlie W., Ahmad, Tariq, Powell, Nick

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Antibody Responses to Influenza Vaccination are Diminished in Patients With Inflammatory Bowel Disease on Infliximab or Tofacitinib von Liu, Zhigang, Alexander, James L, Yee Eng, Kai, Ibraheim, Hajir, Anandabaskaran, Sulak, Saifuddin, Aamir, Constable, Laura, Castro Seoane, Rocio, Bewshea, Claire, Nice, Rachel, D’Mello, Andrea, Jones, Gareth R, Balarajah, Sharmili, Fiorentino, Francesca, Sebastian, Shaji, Irving, Peter M, Hicks, Lucy C, Williams, Horace R T, Kent, Alexandra J, Linger, Rachel, Parkes, Miles, Kok, Klaartje, Patel, Kamal V, Teare, Julian P, Altmann, Daniel M, Boyton, Rosemary J, Hart, Ailsa L, Lees, Charlie W, Goodhand, James R, Kennedy, Nicholas A, Pollock, Katrina M, Ahmad, Tariq, Powell, Nick

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P001 Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and is dependent on the IL23/IFNg axis von Lo, J, Cozzetto, D, Madgwick, M, Sieh, J Y X S, Olbei, M, Alexander, J L, Miguens Blanco, J, Kudo, H, Ibraheim, H, Liu, Z, Castro Seoane, R, Goldin, R, Marchesi, J, Korcsmaros, T, Lord, G, Powell, N

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Antibody responses to influenza vaccination are diminished in patients with inflammatory bowel disease on infliximab or tofacitinib von Liu, Z, Alexander, JL, Eng, KY, Ibraheim, H, Anandabaskaran, S, Saifuddin, A, Constable, L, Seoane, RC, Bewshea, C, Nice, R, D'Mello, A, Jones, GR, Balarajah, S, Fiorentino, F, Sebastian, S, Irving, PM, Hicks, LC, Williams, HRT, Kent, AJ, Linger, R, Parkes, M, Kok, K, Patel, KV, Teare, JP, Altmann, DM, Boyton, RJ, Hart, AL, Lees, CW, Goodhand, JR, Kennedy, NA, Pollock, KM, Ahmad, T, Powell, N, VIP study investigators

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Mesh inlay, mesh kit or native tissue repair for women having repeat anterior or posterior prolapse surgery: randomised controlled trial (PROSPECT) von Hemming, C, Freeman, RM, Smith, ARB, Hagen, S, Montgomery, I, Kilonzo, M, Boyers, D, McDonald, A, McPherson, G, Reid, FM, Terry, Peter, Fattah, Mohamed Abdel, Swan, Lynn, Dallas, Christine, Allan, Angela, Henderson, Christina, Agur, Wael, Henry, Margo, Gilmour, Danielle, Farag, Khalid, Dass, Meenakshi, Reid, Michelle, Toozs‐Hobson, Philip, Latthe, Pallavi, Parsons, Matthew, Williams, Abimbola, Chia, Philip, Rhead, Katrina, Mistry, Raksha, Calvert, Sue, Bowyer, Anne, Cloete, Jenny, Archer, Denise, Kearsley, Nichola, Devlin, Hollie, Matar, Mohamed, Wilson, Toni, Bennett, Caroline, Chan, Yi Ling, Bondili, A, Kitchingman, Judith, Bexhell, Helen, Digesu, Alex, Underwood, Jenny, Singh, Anand, Tincello, Douglas, Fowler, Victoria, Christie, Carla, Fayyad, Abdalla, Bastion, Victoria, Smith, Anthony, Rose, Karen, Green, Linda, Biancardi, Rachel, Kumakech, Wilfred, Connell, Rowan, Lord, Susan, Jones, Sharon, Nolan, Tracey, Casey, Rebecca, Fishwick, Kathryn, Lowry, Tracey, Buckley, Sarah, Townend, Claire, Eckford, Seumas, Eskander, Osama, Belcher, Geraldine, Skinner, Amanda, Passmore, Deborah, Hooper, Paul, Das, Mausumi, Hickman, Emma, Heawood, Sarah, Bombieri, Luigi, Brockman, Paula, King, Angela, Hogston, Patrick, Parkinson, Richard, Jenkins, Elinor, Prashar, Sanjeev, Butler, Julie, Patel, Daksha, Field, Janet, Walker, Rachel, Cunningham, Mishell, Pearson, Sally Anne, Sturley, Rachel, Renton, Caroline, Ballard, Paul, Anderson, Colette, Potts, Julie, Chamberlain, Jonathan, Mercer, Pauline, Visvanathan, Shankar, Dawlatly, Bashir, Maseko, Zandile, El Naqa, Ayman, Afifi, Khaled, Kempson, Sharon, Denyer, Nick

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P535 COVID-19 vaccine-induced neutralising antibody responses against SARS-CoV-2 Omicron BA.4/5 are diminished in patients with inflammatory bowel disease on anti-TNF or JAK-inhibi... von Liu, Z, Alexander, J, Le, K, Zhou, X, Ibraheim, H, Anandabaskaran, S, Saifuddin, A, Lin, K, Mcfarlane, L, Anand, N, Constable, L, Castro-Seoane, R, Nice, R, Bewshea, C, D'Mello, A, Jones, G R, Balarajah, S, Fiorentino, F, Sebastian, S, Irving, P, Hicks, L, Williams, H, Kent, A, Linger, R, Parkes, M, Kok, K, Patel, K V, Teare, J, Altmann, D, Hart, A, Lees, C, Boyton, R, Goodhand, J, Kennedy, N, Pollock, K, Ahmad, T, Powell, N

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