Physiology of Hyperuricemia and Urate-Lowering Treatments von Benn, Caroline L, Dua, Pinky, Gurrell, Rachel, Loudon, Peter, Pike, Andrew, Storer, R Ian, Vangjeli, Ciara

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Enantioselective Organocatalytic Reductive Amination von Storer, R. Ian, Carrera, Diane E, Ni, Yike, MacMillan, David W. C

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A semi-quantitative translational pharmacology analysis to understand the relationship between in vitro ENT1 inhibition and the clinical incidence of dyspnoea and bronchospasm von Rosenbrier Ribeiro, Lyn, Ian Storer, R.

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Squaramides: physical properties, synthesis and applications von Ian Storer, R., Aciro, Caroline, Jones, Lyn H.

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Squaramides: physical properties, synthesis and applications von Storer, R Ian, Aciro, Caroline, Jones, Lyn H

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Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lu... von Jones, Peter, Storer, R. Ian, Sabnis, Yogesh A, Wakenhut, Florian M, Whitlock, Gavin A, England, Katherine S, Mukaiyama, Takasuke, Dehnhardt, Christoph M, Coe, Jotham W, Kortum, Steve W, Chrencik, Jill E, Brown, David G, Jones, Rhys M, Murphy, John R, Yeoh, Thean, Morgan, Paul, Kilty, Iain

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Put a ring on it: application of small aliphatic rings in medicinal chemistry von Bauer, Matthias R, Di Fruscia, Paolo, Lucas, Simon C. C, Michaelides, Iacovos N, Nelson, Jennifer E, Storer, R. Ian, Whitehurst, Benjamin C

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Targeting the cAMP and Transforming Growth Factor‐β Pathway Increases Proliferation to Promote Re‐Epithelialization of Human Stem Cell‐Derived Retinal Pigment Epithelium von Choudhary, Parul, Gutteridge, Alex, Impey, Emma, Storer, R. Ian, Owen, Robert M., Whiting, Paul J., Bictash, Magda, Benn, Caroline L.

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Enantioselective Brønsted Acid-Catalyzed N-Acyliminium Cyclization Cascades von Muratore, Michael E, Holloway, Chloe A, Pilling, Adam W, Storer, R. Ian, Trevitt, Graham, Dixon, Darren J

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Recent progress in sodium channel modulators for pain von Bagal, Sharan K., Chapman, Mark L., Marron, Brian E., Prime, Rebecca, Storer, R. Ian, Swain, Nigel A.

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Ion Channels as Therapeutic Targets: A Drug Discovery Perspective von Bagal, Sharan K, Brown, Alan D, Cox, Peter J, Omoto, Kiyoyuki, Owen, Robert M, Pryde, David C, Sidders, Benjamin, Skerratt, Sarah E, Stevens, Edward B, Storer, R. Ian, Swain, Nigel A

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Design and Evaluation of a Low Hydrogen Bond Donor Count Fragment Screening Set to Aid Hit Generation of PROTACs Intended for Oral Delivery von Whitehurst, Benjamin C., Bauer, Matthias R., Edfeldt, Fredrik, Gunnarsson, Anders, Margreitter, Christian, Rawlins, Philip B., Storer, R. Ian

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Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release von Alexandrou, Aristos J, Brown, Adam R, Chapman, Mark L, Estacion, Mark, Turner, Jamie, Mis, Malgorzata A, Wilbrey, Anna, Payne, Elizabeth C, Gutteridge, Alex, Cox, Peter J, Doyle, Rachel, Printzenhoff, David, Lin, Zhixin, Marron, Brian E, West, Christopher, Swain, Nigel A, Storer, R Ian, Stupple, Paul A, Castle, Neil A, Hounshell, James A, Rivara, Mirko, Randall, Andrew, Dib-Hajj, Sulayman D, Krafte, Douglas, Waxman, Stephen G, Patel, Manoj K, Butt, Richard P, Stevens, Edward B

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Synthesis and functionalisation of a bifunctional normorphan 3D building block for medicinal chemistry von Gomez-Angel, Andres R., Donald, James R., Firth, James D., De Fusco, Claudia, Ian Storer, R., Cox, Daniel J., O’Brien, Peter

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Hit me with your best shot: Integrated hit discovery for the next generation of drug targets von Ashraf, S. Neha, Blackwell, J. Henry, Holdgate, Geoffrey A., Lucas, Simon C.C., Solovyeva, Alisa, Storer, R. Ian, Whitehurst, Benjamin C.

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Discovery and Optimization of the First ATP Competitive Type-III c‑MET Inhibitor von Michaelides, Iacovos N., Collie, Gavin W., Börjesson, Ulf, Vasalou, Christina, Alkhatib, Omar, Barlind, Louise, Cheung, Tony, Dale, Ian L., Embrey, Kevin J., Hennessy, Edward J., Khurana, Puneet, Koh, Cheryl M., Lamb, Michelle L., Liu, Jianming, Moss, Thomas A., O’Neill, Daniel J., Phillips, Christopher, Shaw, Joseph, Snijder, Arjan, Storer, R. Ian, Stubbs, Christopher J., Han, Fujin, Li, Chengzhi, Qiao, Jingchuan, Sun, Dong-Qing, Wang, Jingwen, Wang, Peng, Yang, Wenzhen

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Voltage gated sodium channels as drug discovery targets von Bagal, Sharan K, Marron, Brian E, Owen, Robert M, Storer, R Ian, Swain, Nigel A

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Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders von Lucas, Simon C. C., Ahmed, Afshan, Ashraf, S. Neha, Argyrou, Argyrides, Bauer, Matthias R., De Donatis, Gian Marco, Demanze, Sylvain, Eisele, Frederik, Fusani, Lucia, Hock, Andreas, Kadamur, Ganesh, Li, Shuyou, Macmillan-Jones, Abigail, Michaelides, Iacovos N., Phillips, Christopher, Rehnström, Marie, Richter, Magdalena, Rodrigo-Brenni, Monica C., Shilliday, Fiona, Wang, Peng, Storer, R. Ian

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Discovery of Clinical Candidate 4‑[2-(5-Amino‑1H‑pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro‑N‑1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Dia... von Swain, Nigel. A, Batchelor, Dave, Beaudoin, Serge, Bechle, Bruce M, Bradley, Paul A, Brown, Alan D, Brown, Bruce, Butcher, Ken J, Butt, Richard P, Chapman, Mark L, Denton, Stephen, Ellis, David, Galan, Sebastien R. G, Gaulier, Steven M, Greener, Ben S, de Groot, Marcel J, Glossop, Mel S, Gurrell, Ian K, Hannam, Jo, Johnson, Matthew S, Lin, Zhixin, Markworth, Christopher J, Marron, Brian E, Millan, David S, Nakagawa, Shoko, Pike, Andy, Printzenhoff, David, Rawson, David J, Ransley, Sarah J, Reister, Steven M, Sasaki, Kosuke, Storer, R. Ian, Stupple, Paul A, West, Christopher W

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Delineating the Ligand–Receptor Interactions That Lead to Biased Signaling at the μ‑Opioid Receptor von Kelly, Brendan, Hollingsworth, Scott A., Blakemore, David C., Owen, Robert M., Storer, R. Ian, Swain, Nigel A., Aydin, Deniz, Torella, Rubben, Warmus, Joseph S., Dror, Ron O.

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