Genomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumors von Dienstmann, R., Rodon, J., Prat, A., Perez-Garcia, J., Adamo, B., Felip, E., Cortes, J., Iafrate, A.J., Nuciforo, P., Tabernero, J.

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Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition von Hata, Aaron N, Niederst, Matthew J, Archibald, Hannah L, Gomez-Caraballo, Maria, Siddiqui, Faria M, Mulvey, Hillary E, Maruvka, Yosef E, Ji, Fei, Bhang, Hyo-eun C, Krishnamurthy Radhakrishna, Viveksagar, Siravegna, Giulia, Hu, Haichuan, Raoof, Sana, Lockerman, Elizabeth, Kalsy, Anuj, Lee, Dana, Keating, Celina L, Ruddy, David A, Damon, Leah J, Crystal, Adam S, Costa, Carlotta, Piotrowska, Zofia, Bardelli, Alberto, Iafrate, Anthony J, Sadreyev, Ruslan I, Stegmeier, Frank, Getz, Gad, Sequist, Lecia V, Faber, Anthony C, Engelman, Jeffrey A

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Impact of EML4-ALK Variant on Resistance Mechanisms and Clinical Outcomes in ALK-Positive Lung Cancer von Lin, Jessica J, Zhu, Viola W, Yoda, Satoshi, Yeap, Beow Y, Schrock, Alexa B, Dagogo-Jack, Ibiayi, Jessop, Nicholas A, Jiang, Ginger Y, Le, Long P, Gowen, Kyle, Stephens, Philip J, Ross, Jeffrey S, Ali, Siraj M, Miller, Vincent A, Johnson, Melissa L, Lovly, Christine M, Hata, Aaron N, Gainor, Justin F, Iafrate, Anthony J, Shaw, Alice T, Ou, Sai-Hong Ignatius

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Identification of Oncogenic Mutations and Gene Fusions in the Follicular Variant of Papillary Thyroid Carcinoma von McFadden, David G, Dias-Santagata, Dora, Sadow, Peter M, Lynch, Kerry D, Lubitz, Carrie, Donovan, Samuel E, Zheng, Zongli, Le, Long, Iafrate, A. J, Daniels, Gilbert H

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Universal screening of both endometrial and colon cancers increases the detection of Lynch syndrome von Adar, Tomer, Rodgers, Linda H., Shannon, Kristen M., Yoshida, Makoto, Ma, Tianle, Mattia, Anthony, Lauwers, Gregory Y., Iafrate, Anthony J., Hartford, Nicole M., Oliva, Esther, Chung, Daniel C.

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HIF1A signaling selectively supports proliferation of breast cancer in the brain von Ebright, Richard Y., Zachariah, Marcus A., Micalizzi, Douglas S., Wittner, Ben S., Niederhoffer, Kira L., Nieman, Linda T., Chirn, Brian, Wiley, Devon F., Wesley, Benjamin, Shaw, Brian, Nieblas-Bedolla, Edwin, Atlas, Lian, Szabolcs, Annamaria, Iafrate, Anthony J., Toner, Mehmet, Ting, David T., Brastianos, Priscilla K., Haber, Daniel A., Maheswaran, Shyamala

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A tailored approach to BRAF and MLH1 methylation testing in a universal screening program for Lynch syndrome von Adar, Tomer, Rodgers, Linda H, Shannon, Kristen M, Yoshida, Makoto, Ma, Tianle, Mattia, Anthony, Lauwers, Gregory Y, Iafrate, Anthony J, Chung, Daniel C

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Genotyping cancer-associated genes in chordoma identifies mutations in oncogenes and areas of chromosomal loss involving CDKN2A, PTEN, and SMARCB1 von Choy, Edwin, MacConaill, Laura E, Cote, Gregory M, Le, Long P, Shen, Jacson K, Nielsen, Gunnlaugur P, Iafrate, Anthony J, Garraway, Levi A, Hornicek, Francis J, Duan, Zhenfeng

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Phase II study of gemcitabine, oxaliplatin in combination with panitumumab in KRAS wild-type unresectable or metastatic biliary tract and gallbladder cancer von Hezel, A F, Noel, M S, Allen, J N, Abrams, T A, Yurgelun, M, Faris, J E, Goyal, L, Clark, J W, Blaszkowsky, L S, Murphy, J E, Zheng, H, Khorana, A A, Connolly, G C, Hyrien, O, Baran, A, Herr, M, Ng, K, Sheehan, S, Harris, D J, Regan, E, Borger, D R, Iafrate, A J, Fuchs, C, Ryan, D P, Zhu, A X

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Clinicopathological and molecular features of SF3B1-mutated myeloproliferative neoplasms von Boiocchi, Leonardo, Hasserjian, Robert P., Pozdnyakova, Olga, Wong, Waihay J., Lennerz, Jochen K., Le, Long Phi, Dias-Santagata, Dora, Iafrate, Anthony J., Hobbs, Gabriela S., Nardi, Valentina

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ESMO recommendations on the standard methods to detect NTRK fusions in daily practice and clinical research von Marchiò, C., Scaltriti, M., Ladanyi, M., Iafrate, A.J., Bibeau, F., Dietel, M., Hechtman, J.F., Troiani, T., López-Rios, F., Douillard, J.-Y., Andrè, F., Reis-Filho, J.S.

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Crizotinib in ROS1-rearranged advanced non-small-cell lung cancer (NSCLC): updated results, including overall survival, from PROFILE 1001 von Shaw, A.T., Riely, G.J., Bang, Y.-J., Kim, D.-W., Camidge, D.R., Solomon, B.J., Varella-Garcia, M., Iafrate, A.J., Shapiro, G.I., Usari, T., Wang, S.C., Wilner, K.D., Clark, J.W., Ou, S.-H.I.

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MGMT METHYLATION IS A PROGNOSTIC BIOMARKER IN ELDERLY PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA von GERSTNER, E. R, YIP, S, WANG, D. L, LOUIS, D. N, IAFRATE, A. J, BATCHELOR, T. T

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Polyclonal RB1 mutations and acquired resistance to CDK 4/6 inhibitors in patients with metastatic breast cancer von Condorelli, R., Spring, L., O’Shaughnessy, J., Lacroix, L., Bailleux, C., Scott, V., Dubois, J., Nagy, R.J., Lanman, R.B., Iafrate, A.J., Andre, F., Bardia, A.

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Mutational analysis and clinical correlation of metastatic colorectal cancer von Russo, Andrea L., Borger, Darrell R., Szymonifka, Jackie, Ryan, David P., Wo, Jennifer Y., Blaszkowsky, Lawrence S., Kwak, Eunice L., Allen, Jill N., Wadlow, Raymond C., Zhu, Andrew X., Murphy, Janet E., Faris, Jason E., Dias‐Santagata, Dora, Haigis, Kevin M., Ellisen, Leif W., Iafrate, Anthony J., Hong, Theodore S.

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Activation of PI3K Signaling in Merkel Cell Carcinoma von NARDI, Valentina, SONG, Youngchul, TSAO, Hensin, SETTLEMAN, Jeffrey, RYAN, David P, BORGER, Darrell R, BHAN, Atul K, HOANG, Mai P, LAFRATE, Anthony J, CUSACK, James C, ENGELMAN, Jeffrey A, DIAS-SANTAGATA, Dora, SANTAMARIA-BARRIA, Juan A, COSPER, Arjola K, LAM, Quynh, FABER, Anthony C, BOLAND, Genevieve M, YEAP, Beow Y, BERGETHON, Kristin, SCIALABBA, Vanessa L

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Acute Renal Endothelial Injury During Marrow Recovery in a Cohort of Combined Kidney and Bone Marrow Allografts von Farris, A.B., Taheri, D., Kawai, T., Fazlollahi, L., Wong, W., Tolkoff‐Rubin, N., Spitzer, T. R., Iafrate, A. J., Preffer, F. I., LoCascio, S. A., Sprangers, B., Saidman, S., Smith, R. N., Cosimi, A. B., Sykes, M., Sachs, D. H., Colvin, R. B.

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HER2 expression identifies dynamic functional states within circulating breast cancer cells von Jordan, Nicole Vincent, Bardia, Aditya, Wittner, Ben S., Benes, Cyril, Ligorio, Matteo, Zheng, Yu, Yu, Min, Sundaresan, Tilak K., Licausi, Joseph A., Desai, Rushil, O’Keefe, Ryan M., Ebright, Richard Y., Boukhali, Myriam, Sil, Srinjoy, Onozato, Maristela L., Iafrate, Anthony J., Kapur, Ravi, Sgroi, Dennis, Ting, David T., Toner, Mehmet, Ramaswamy, Sridhar, Haas, Wilhelm, Maheswaran, Shyamala, Haber, Daniel A.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine response in adults with predominantly antibody deficiency von Zhang, Anna M., Elmoursi, Ahmed, DiGiacomo, Daniel V., Zhou, Baijun, Tandon, Megha, Hong, Joseph S., Yang, Nancy J., Ong, Mei-Sing, Dighe, Anand S., Berrios, Cristhian, Poznansky, Mark C., Iafrate, Anthony J., Naranbhai, Vivek, Balazs, Alejandro, Pillai, Shiv, Farmer, Jocelyn R., Barmettler, Sara

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RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer von Niederst, Matthew J., Sequist, Lecia V., Poirier, John T., Mermel, Craig H., Lockerman, Elizabeth L., Garcia, Angel R., Katayama, Ryohei, Costa, Carlotta, Ross, Kenneth N., Moran, Teresa, Howe, Emily, Fulton, Linnea E., Mulvey, Hillary E., Bernardo, Lindsay A., Mohamoud, Farhiya, Miyoshi, Norikatsu, VanderLaan, Paul A., Costa, Daniel B., Jänne, Pasi A., Borger, Darrell R., Ramaswamy, Sridhar, Shioda, Toshi, Iafrate, Anthony J., Getz, Gad, Rudin, Charles M., Mino-Kenudson, Mari, Engelman, Jeffrey A.

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