Computational Modeling of Pancreatic Cancer Reveals Kinetics of Metastasis Suggesting Optimum Treatment Strategies von Haeno, Hiroshi, Gonen, Mithat, Davis, Meghan B., Herman, Joseph M., Iacobuzio-Donahue, Christine A., Michor, Franziska

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ConDoR: tumor phylogeny inference with a copy-number constrained mutation loss model von Sashittal, Palash, Zhang, Haochen, Iacobuzio-Donahue, Christine A, Raphael, Benjamin J

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Ampullary cancer: Evaluation of somatic and germline genetic alterations and association with clinical outcomes von Wong, Winston, Lowery, Maeve A., Berger, Michael F., Kemel, Yelena, Taylor, Barry, Zehir, Ahmet, Srinivasan, Preethi, Bandlamudi, Chaitanya, Chou, Joanne, Capanu, Marinela, Varghese, Anna, Yu, Kenneth H., Iacobuzio‐Donahue, Christine A., Shia, Jinru, Klimstra, David S., Jarnagin, William R., Stadler, Zsofia K., O’Reilly, Eileen M.

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GATA6 activates Wnt signaling in pancreatic cancer by negatively regulating the Wnt antagonist Dickkopf-1 von Zhong, Yi, Wang, Zheng, Fu, Baojin, Pan, Fan, Yachida, Shinichi, Dhara, Mousumi, Albesiano, Emilia, Li, Li, Naito, Yoshiki, Vilardell, Felip, Cummings, Christopher, Martinelli, Paola, Li, Ang, Yonescu, Raluca, Ma, Qingyong, Griffin, Constance A, Real, Francisco X, Iacobuzio-Donahue, Christine A

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Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells von Klemm, Florian, Maas, Roeltje R., Bowman, Robert L., Kornete, Mara, Soukup, Klara, Nassiri, Sina, Brouland, Jean-Philippe, Iacobuzio-Donahue, Christine A., Brennan, Cameron, Tabar, Viviane, Gutin, Philip H., Daniel, Roy T., Hegi, Monika E., Joyce, Johanna A.

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Molecular pathways in pancreatic carcinogenesis von Macgregor-Das, Anne M., Iacobuzio-Donahue, Christine A.

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Genetic evolution of pancreatic cancer: lessons learnt from the pancreatic cancer genome sequencing project von Iacobuzio-Donahue, Christine A

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Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations von Hu, Zishuo I, Shia, Jinru, Stadler, Zsofia K, Varghese, Anna M, Capanu, Marinela, Salo-Mullen, Erin, Lowery, Maeve A, Diaz, Jr, Luis A, Mandelker, Diana, Yu, Kenneth H, Zervoudakis, Alice, Kelsen, David P, Iacobuzio-Donahue, Christine A, Klimstra, David S, Saltz, Leonard B, Sahin, Ibrahim H, O'Reilly, Eileen M

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Minimal functional driver gene heterogeneity among untreated metastases von Reiter, Johannes G, Makohon-Moore, Alvin P, Gerold, Jeffrey M, Heyde, Alexander, Attiyeh, Marc A, Kohutek, Zachary A, Tokheim, Collin J, Brown, Alexia, DeBlasio, Rayne M, Niyazov, Juliana, Zucker, Amanda, Karchin, Rachel, Kinzler, Kenneth W, Iacobuzio-Donahue, Christine A, Vogelstein, Bert, Nowak, Martin A

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Ordered and deterministic cancer genome evolution after p53 loss von Baslan, Timour, Morris, John P., Zhao, Zhen, Reyes, Jose, Ho, Yu-Jui, Tsanov, Kaloyan M., Bermeo, Jonathan, Tian, Sha, Zhang, Sean, Askan, Gokce, Yavas, Aslihan, Lecomte, Nicolas, Erakky, Amanda, Varghese, Anna M., Zhang, Amy, Kendall, Jude, Ghiban, Elena, Chorbadjiev, Lubomir, Wu, Jie, Dimitrova, Nevenka, Chadalavada, Kalyani, Nanjangud, Gouri J., Bandlamudi, Chaitanya, Gong, Yixiao, Donoghue, Mark T. A., Socci, Nicholas D., Krasnitz, Alex, Notta, Faiyaz, Leach, Steve D., Iacobuzio-Donahue, Christine A., Lowe, Scott W.

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Cancer biology as revealed by the research autopsy von Iacobuzio-Donahue, Christine A., Michael, Chelsea, Baez, Priscilla, Kappagantula, Rajya, Hooper, Jody E., Hollman, Travis J.

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Reconstructing metastatic seeding patterns of human cancers von Reiter, Johannes G., Makohon-Moore, Alvin P., Gerold, Jeffrey M., Bozic, Ivana, Chatterjee, Krishnendu, Iacobuzio-Donahue, Christine A., Vogelstein, Bert, Nowak, Martin A.

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The pathology and genetics of metastatic pancreatic cancer von Yachida, Shinichi, Iacobuzio-Donahue, Christine A

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Epigenetic changes in cancer von Iacobuzio-Donahue, Christine A

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Metastatic progression is associated with dynamic changes in the local microenvironment von Aiello, Nicole M., Bajor, David L., Norgard, Robert J., Sahmoud, Amine, Bhagwat, Neha, Pham, Minh N., Cornish, Toby C., Iacobuzio-Donahue, Christine A., Vonderheide, Robert H., Stanger, Ben Z.

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Circulating Tumor Cell Phenotype Predicts Recurrence and Survival in Pancreatic Adenocarcinoma von Poruk, Katherine E, Valero, Vicente, Saunders, Tyler, Blackford, Amanda L, Griffin, James F, Poling, Justin, Hruban, Ralph H, Anders, Robert A, Herman, Joseph, Zheng, Lei, Rasheed, Zeshaan A, Laheru, Daniel A, Ahuja, Nita, Weiss, Matthew J, Cameron, John L, Goggins, Michael, Iacobuzio-Donahue, Christine A, Wood, Laura D, Wolfgang, Christopher L

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Mapping the tumor stress network reveals dynamic shifts in the stromal oxidative stress response von Lior, Chen, Barki, Debra, Halperin, Coral, Iacobuzio-Donahue, Christine A., Kelsen, David, Shouval, Ruth Scherz

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BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling von Shaashua, Lee, Ben-Shmuel, Aviad, Pevsner-Fischer, Meirav, Friedman, Gil, Levi-Galibov, Oshrat, Nandakumar, Subhiksha, Barki, Debra, Nevo, Reinat, Brown, Lauren E., Zhang, Wenhan, Stein, Yaniv, Lior, Chen, Kim, Han Sang, Bojmar, Linda, Jarnagin, William R., Lecomte, Nicolas, Mayer, Shimrit, Stok, Roni, Bishara, Hend, Hamodi, Rawand, Levy-Lahad, Ephrat, Golan, Talia, Porco, John A., Iacobuzio-Donahue, Christine A., Schultz, Nikolaus, Tuveson, David A., Lyden, David, Kelsen, David, Scherz-Shouval, Ruth

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Clinical Significance of the Genetic Landscape of Pancreatic Cancer and Implications for Identification of Potential Long-term Survivors von YACHIDA, Shinichi, WHITE, Catherine M, HRUBAN, Ralph H, KLEIN, Alison P, JONES, Sian, VELCULESCU, Victor, WOLFGANG, Christopher L, LACOBUZIO-DONAHUE, Christine A, NAITO, Yoshiki, YI ZHONG, BROSNAN, Jacqueline A, MACGREGOR-DAS, Anne M, MORGAN, Richard A, SAUNDERS, Tyler, LAHERU, Daniel A, HERMAN, Joseph M

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Pancreatic cancer stem cells may define tumor stroma characteristics and recurrence patterns in pancreatic ductal adenocarcinoma von Askan, Gokce, Sahin, Ibrahim Halil, Chou, Joanne F., Yavas, Aslihan, Capanu, Marinela, Iacobuzio-Donahue, Christine A., Basturk, Olca, O'Reilly, Eileen M.

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