The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes von Anzai, Atsushi, Choi, Jennifer L, He, Shun, Fenn, Ashley M, Nairz, Manfred, Rattik, Sara, McAlpine, Cameron S, Mindur, John E, Chan, Christopher T, Iwamoto, Yoshiko, Tricot, Benoit, Wojtkiewicz, Gregory R, Weissleder, Ralph, Libby, Peter, Nahrendorf, Matthias, Stone, James R, Becher, Burkhard, Swirski, Filip K

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p53 dynamics vary between tissues and are linked with radiation sensitivity von Stewart-Ornstein, Jacob, Iwamoto, Yoshiko, Miller, Miles A., Prytyskach, Mark A., Ferretti, Stephane, Holzer, Philipp, Kallen, Joerg, Furet, Pascal, Jambhekar, Ashwini, Forrester, William C., Weissleder, Ralph, Lahav, Galit

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Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy von Pfirschke, Christina, Engblom, Camilla, Rickelt, Steffen, Cortez-Retamozo, Virna, Garris, Christopher, Pucci, Ferdinando, Yamazaki, Takahiro, Poirier-Colame, Vichnou, Newton, Andita, Redouane, Younes, Lin, Yi-Jang, Wojtkiewicz, Gregory, Iwamoto, Yoshiko, Mino-Kenudson, Mari, Huynh, Tiffany G., Hynes, Richard O., Freeman, Gordon J., Kroemer, Guido, Zitvogel, Laurence, Weissleder, Ralph, Pittet, Mikael J.

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Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure von Sager, Hendrik B, Hulsmans, Maarten, Lavine, Kory J, Moreira, Marina B, Heidt, Timo, Courties, Gabriel, Sun, Yuan, Iwamoto, Yoshiko, Tricot, Benoit, Khan, Omar F, Dahlman, James E, Borodovsky, Anna, Fitzgerald, Kevin, Anderson, Daniel G, Weissleder, Ralph, Libby, Peter, Swirski, Filip K, Nahrendorf, Matthias

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Cardiac macrophages promote diastolic dysfunction von Hulsmans, Maarten, Sager, Hendrik B, Roh, Jason D, Valero-Muñoz, María, Houstis, Nicholas E, Iwamoto, Yoshiko, Sun, Yuan, Wilson, Richard M, Wojtkiewicz, Gregory, Tricot, Benoit, Osborne, Michael T, Hung, Judy, Vinegoni, Claudio, Naxerova, Kamila, Sosnovik, David E, Zile, Michael R, Bradshaw, Amy D, Liao, Ronglih, Tawakol, Ahmed, Weissleder, Ralph, Rosenzweig, Anthony, Swirski, Filip K, Sam, Flora, Nahrendorf, Matthias

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Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis von Heyde, Alexander, Rohde, David, McAlpine, Cameron S., Zhang, Shuang, Hoyer, Friedrich F., Gerold, Jeffrey M., Cheek, David, Iwamoto, Yoshiko, Schloss, Maximilian J., Vandoorne, Katrien, Iborra-Egea, Oriol, Muñoz-Guijosa, Christian, Bayes-Genis, Antoni, Reiter, Johannes G., Craig, Morgan, Swirski, Filip K., Nahrendorf, Matthias, Nowak, Martin A., Naxerova, Kamila

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Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction von Heidt, Timo, Courties, Gabriel, Dutta, Partha, Sager, Hendrik B, Sebas, Matt, Iwamoto, Yoshiko, Sun, Yuan, Da Silva, Nicolas, Panizzi, Peter, van der Lahn, Anja M, Swirski, Filip K, Weissleder, Ralph, Nahrendorf, Matthias

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Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells von Spiegel, Asaf, Brooks, Mary W, Houshyar, Samin, Reinhardt, Ferenc, Ardolino, Michele, Fessler, Evelyn, Chen, Michelle B, Krall, Jordan A, DeCock, Jasmine, Zervantonakis, Ioannis K, Iannello, Alexandre, Iwamoto, Yoshiko, Cortez-Retamozo, Virna, Kamm, Roger D, Pittet, Mikael J, Raulet, David H, Weinberg, Robert A

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Local proliferation dominates lesional macrophage accumulation in atherosclerosis von Robbins, Clinton S, Hilgendorf, Ingo, Weber, Georg F, Theurl, Igor, Iwamoto, Yoshiko, Figueiredo, Jose-Luiz, Gorbatov, Rostic, Sukhova, Galina K, Gerhardt, Louisa M S, Smyth, David, Zavitz, Caleb C J, Shikatani, Eric A, Parsons, Michael, van Rooijen, Nico, Lin, Herbert Y, Husain, Mansoor, Libby, Peter, Nahrendorf, Matthias, Weissleder, Ralph, Swirski, Filip K

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Monocytes re-enter the bone marrow during fasting and alter the host response to infection von Janssen, Henrike, Kahles, Florian, Liu, Dan, Downey, Jeffrey, Koekkoek, Laura L., Roudko, Vladimir, D’Souza, Darwin, McAlpine, Cameron S., Halle, Lennard, Poller, Wolfram C., Chan, Christopher T., He, Shun, Mindur, John E., Kiss, Máté G., Singh, Sumnima, Anzai, Atsushi, Iwamoto, Yoshiko, Kohler, Rainer H., Chetal, Kashish, Sadreyev, Ruslan I., Weissleder, Ralph, Kim-Schulze, Seunghee, Merad, Miriam, Nahrendorf, Matthias, Swirski, Filip K.

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Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis von Weber, Georg F., Chousterman, Benjamin G., He, Shun, Fenn, Ashley M., Nairz, Manfred, Anzai, Atsushi, Brenner, Thorsten, Uhle, Florian, Iwamoto, Yoshiko, Robbins, Clinton S., Noiret, Lorette, Maier, Sarah L., Zönnchen, Tina, Rahbari, Nuh N., Schölch, Sebastian, Klotzsche-von Ameln, Anne, Chavakis, Triantafyllos, Weitz, Jürgen, Hofer, Stefan, Weigand, Markus A., Nahrendorf, Matthias, Weissleder, Ralph, Swirski, Filip K.

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Therapeutic siRNA silencing in inflammatory monocytes in mice von Weissleder, Ralph, Nahrendorf, Matthias, Leuschner, Florian, Dutta, Partha, Gorbatov, Rostic, Novobrantseva, Tatiana I, Donahoe, Jessica S, Courties, Gabriel, Lee, Kang Mi, Kim, James I, Markmann, James F, Marinelli, Brett, Panizzi, Peter, Lee, Won Woo, Iwamoto, Yoshiko, Milstein, Stuart, Epstein-Barash, Hila, Cantley, William, Wong, Jamie, Cortez-Retamozo, Virna, Newton, Andita, Love, Kevin, Libby, Peter, Pittet, Mikael J, Swirski, Filip K, Koteliansky, Victor, Langer, Robert, Anderson, Daniel G

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Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis von Leuschner, Florian, Rauch, Philipp J, Ueno, Takuya, Gorbatov, Rostic, Marinelli, Brett, Lee, Won Woo, Dutta, Partha, Wei, Ying, Robbins, Clinton, Iwamoto, Yoshiko, Sena, Brena, Chudnovskiy, Aleksey, Panizzi, Peter, Keliher, Edmund, Higgins, John M, Libby, Peter, Moskowitz, Michael A, Pittet, Mikael J, Swirski, Filip K, Weissleder, Ralph, Nahrendorf, Matthias

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Bone Marrow Endothelial Cells Regulate Myelopoiesis in Diabetes Mellitus von Hoyer, Friedrich Felix, Zhang, Xinyi, Coppin, Emilie, Vasamsetti, Sathish Babu, Modugu, Ganesh, Schloss, Maximilian J., Rohde, David, McAlpine, Cameron S., Iwamoto, Yoshiko, Libby, Peter, Naxerova, Kamila, Swirski, Filip K., Dutta, Partha, Nahrendorf, Matthias

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Origins of tumor-associated macrophages and neutrophils von Cortez-Retamozo, Virna, Etzrodt, Martin, Newton, Andita, Rauch, Philipp J, Chudnovskiy, Aleksey, Berger, Cedric, Ryan, Russell J. H, Iwamoto, Yoshiko, Marinelli, Brett, Gorbatov, Rostic, Forghani, Reza, Novobrantseva, Tatiana I, Koteliansky, Victor, Figueiredo, Jose-Luiz, Chen, John W, Anderson, Daniel G, Nahrendorf, Matthias, Swirski, Filip K, Weissleder, Ralph, Pittet, Mikael J

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Monocyte-Directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-Prone Mice von Majmudar, Maulik D, Keliher, Edmund J, Heidt, Timo, Leuschner, Florian, Truelove, Jessica, Sena, Brena F, Gorbatov, Rostic, Iwamoto, Yoshiko, Dutta, Partha, Wojtkiewicz, Gregory, Courties, Gabriel, Sebas, Matt, Borodovsky, Anna, Fitzgerald, Kevin, Nolte, Marc W, Dickneite, Gerhard, Chen, John W, Anderson, Daniel G, Swirski, Filip K, Weissleder, Ralph, Nahrendorf, Matthias

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Innate Response Activator B Cells Protect Against Microbial Sepsis von Rauch, Philipp J., Chudnovskiy, Aleksey, Robbins, Clinton S., Weber, Georg F., Etzrodt, Martin, Hilgendorf, Ingo, Tiglao, Elizabeth, Figueiredo, Jose-Luiz, Iwamoto, Yoshiko, Theurl, Igor, Gorbatov, Rostic, Waring, Michael T., Chicoine, Adam T., Mouded, Majd, Pittet, Mikael J., Nahrendorf, Matthias, Weissleder, Ralph, Swirski, Filip K.

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In Vivo Silencing of the Transcription Factor IRF5 Reprograms the Macrophage Phenotype and Improves Infarct Healing von Courties, Gabriel, PhD, Heidt, Timo, MD, Sebas, Matthew, BS, Iwamoto, Yoshiko, BS, Jeon, Derrick, MS, Truelove, Jessica, BS, Tricot, Benoit, MS, Wojtkiewicz, Greg, MS, Dutta, Partha, PhD, Sager, Hendrik B., MD, Borodovsky, Anna, PhD, Novobrantseva, Tatiana, PhD, Klebanov, Boris, PhD, Fitzgerald, Kevin, PhD, Anderson, Daniel G., PhD, Libby, Peter, MD, Swirski, Filip K., PhD, Weissleder, Ralph, MD, PhD, Nahrendorf, Matthias, MD, PhD

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Macrophages retain hematopoietic stem cells in the spleen via VCAM-1 von Dutta, Partha, Hoyer, Friedrich Felix, Grigoryeva, Lubov S, Sager, Hendrik B, Leuschner, Florian, Courties, Gabriel, Borodovsky, Anna, Novobrantseva, Tatiana, Ruda, Vera M, Fitzgerald, Kevin, Iwamoto, Yoshiko, Wojtkiewicz, Gregory, Sun, Yuan, Da Silva, Nicolas, Libby, Peter, Anderson, Daniel G, Swirski, Filip K, Weissleder, Ralph, Nahrendorf, Matthias

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Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease von Keliher, Edmund J., Ye, Yu-Xiang, Wojtkiewicz, Gregory R., Aguirre, Aaron D., Tricot, Benoit, Senders, Max L., Groenen, Hannah, Fay, Francois, Perez-Medina, Carlos, Calcagno, Claudia, Carlucci, Giuseppe, Reiner, Thomas, Sun, Yuan, Courties, Gabriel, Iwamoto, Yoshiko, Kim, Hye-Yeong, Wang, Cuihua, Chen, John W., Swirski, Filip K., Wey, Hsiao-Ying, Hooker, Jacob, Fayad, Zahi A., Mulder, Willem J. M., Weissleder, Ralph, Nahrendorf, Matthias

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