Status of the Current Treatment Options and Potential Future Targets in Uterine Leiomyosarcoma: A Review von Asano, Hiroshi, Isoe, Toshiyuki, Ito, Yoichi M, Nishimoto, Naoki, Watanabe, Yudai, Yokoshiki, Saki, Watari, Hidemichi

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Protocol for treating lumbar spinal canal stenosis with a combination of ultrapurified, allogenic bone marrow-derived mesenchymal stem cells and in situ-forming gel: a multicentre,... von Sudo, Hideki, Miyakoshi, Takashi, Watanabe, Yudai, Ito, Yoichi M, Kahata, Kaoru, Tha, Khin Khin, Yokota, Nozomi, Kato, Hiroe, Terada, Tomoko, Iwasaki, Norimasa, Arato, Teruyo, Sato, Norihiro, Isoe, Toshiyuki

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Efficacy of bezafibrate for preventing myopathic attacks in patients with very long-chain acyl-CoA dehydrogenase deficiency von Shiraishi, Hideaki, Yamada, Kenji, Egawa, Kiyoshi, Ishige, Mika, Ochi, Fumihiro, Watanabe, Asami, Kawakami, Sanae, Kuzume, Kazuyo, Watanabe, Kenji, Sameshima, Koji, Nakamagoe, Kiyotaka, Tamaoka, Akira, Asahina, Naoko, Yokoshiki, Saki, Kobayashi, Keiko, Miyakoshi, Takashi, Oba, Koji, Isoe, Toshiyuki, Hayashi, Hiroshi, Yamaguchi, Seiji, Sato, Norihiro

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A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model von Ohno, Hiroaki, Kubo, Kazuo, Murooka, Hideko, Kobayashi, Yoshiko, Nishitoba, Tsuyoshi, Shibuya, Masabumi, Yoneda, Toshiyuki, Isoe, Toshiyuki

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Novel Potent Orally Active Selective VEGFR-2 Tyrosine Kinase Inhibitors:  Synthesis, Structure−Activity Relationships, and Antitumor Activities of N-Phenyl-N‘-{4-(4-quinolyloxy)phe... von Kubo, Kazuo, Shimizu, Toshiyuki, Ohyama, Shin-ichi, Murooka, Hideko, Iwai, Akemi, Nakamura, Kazuhide, Hasegawa, Kazumasa, Kobayashi, Yoshiko, Takahashi, Noriko, Takahashi, Kazumi, Kato, Shinichiro, Izawa, Toshio, Isoe, Toshiyuki

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Exploratory clinical trial on the safety and capability of dMD-001 in lumbar disc herniation: Study protocol for a first-in-human pilot study von Yamada, Katsuhisa, Kenichiro, Maeda, Ito, Yoichi M., Inage, Fujio, Isoe, Toshiyuki, Yokota, Nozomi, Sugita, Osamu, Sato, Norihiro, Tha, Khin Khin, Iwasaki, Norimasa, Arato, Teruyo, Sudo, Hideki

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Anti‐tumor activity and tumor vessel normalization by the vascular endothelial growth factor receptor tyrosine kinase inhibitor KRN951 in a rat peritoneal disseminated tumor model... von Taguchi, Eri, Nakamura, Kazuhide, Miura, Toru, Shibuya, Masabumi, Isoe, Toshiyuki

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Open-label clinical trial of bezafibrate treatment in patients with fatty acid oxidation disorders in Japan; 2nd report QOL survey von Shiraishi, Hideaki, Yamada, Kenji, Oki, Eishin, Ishige, Mika, Fukao, Toshiyuki, Hamada, Yusuke, Sakai, Norio, Ochi, Fumihiro, Watanabe, Asami, Kawakami, Sanae, Kuzume, Kazuyo, Watanabe, Kenji, Sameshima, Koji, Nakamagoe, Kiyotaka, Tamaoka, Akira, Asahina, Naoko, Yokoshiki, Saki, Miyakoshi, Takashi, Oba, Koji, Isoe, Toshiyuki, Hayashi, Hiroshi, Yamaguchi, Seiji, Sato, Norihiro

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Open-label clinical trial of bezafibrate treatment in patients with fatty acid oxidation disorders in Japan von Yamada, Kenji, Shiraishi, Hideaki, Oki, Eishin, Ishige, Mika, Fukao, Toshiyuki, Hamada, Yusuke, Sakai, Norio, Ochi, Fumihiro, Watanabe, Asami, Kawakami, Sanae, Kuzume, Kazuyo, Watanabe, Kenji, Sameshima, Koji, Nakamagoe, Kiyotaka, Tamaoka, Akira, Asahina, Naoko, Yokoshiki, Saki, Miyakoshi, Takashi, Ono, Kota, Oba, Koji, Isoe, Toshiyuki, Hayashi, Hiroshi, Yamaguchi, Seiji, Sato, Norihiro

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KRN633: A selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth von Nakamura, Kazuhide, Yamamoto, Atsushi, Kamishohara, Masaru, Takahashi, Kazumi, Taguchi, Eri, Miura, Toru, Kubo, Kazuo, Shibuya, Masabumi, Isoe, Toshiyuki

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Eribulin for patients with metastatic extramammary Paget disease: Study protocol for a single‐arm phase II trial von Maeda, Takuya, Yanagi, Teruki, Tokuchi, Keiko, Funakoshi, Takeru, Horie, Nao, Isoe, Toshiyuki, Ito, Yoichi M., Sato, Norihiro, Ujiie, Hideyuki

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KRN951, a highly potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, has antitumor activities and affects functional vascular properties von NAKAMURA, Kazuhide, TAGUCHI, Eri, SUZUKI, Rika, KUBO, Kinya, SHIBUYA, Masabumi, ISOE, Toshiyuki, MIURA, Toru, YAMAMOTO, Atsushi, TAKAHASHI, Kazumi, BICHAT, Francis, GUILBAUD, Nicolas, HASEGAWA, Kazumasa, KUBO, Kazuo, FUJIWARA, Yasunari

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Biologic and Clinical Activity of Tivozanib (AV-951, KRN-951), a Selective Inhibitor of VEGF Receptor-1, -2, and -3 Tyrosine Kinases, in a 4-Week-On, 2-Week-Off Schedule in Patient... von ESKENS, Ferry A. L. M, DE JONGE, Maja J. A, VERWEIJ, Jaap, BHARGAVA, Pankaj, ISOE, Toshiyuki, COTREAU, Monette M, ESTEVES, Brooke, HAYASHI, Kunihiko, BURGER, Herman, THOMEER, Maarten, VAN DOORN, Leni

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Abstract CT137: Phase II study of trastuzumab and docetaxel therapy in patients with HER2-positive recurrent and/or metastatic salivary gland carcinoma von Kinoshita, Ichiro, Kano, Satoshi, Shimizu, Yasushi, Kiyota, Naomi, Tada, Yuichiro, Ijichi, Kei, Yamazaki, Tmoko, Homma, Akihiro, Ito, Yoichi M., Ono, Kota, Kobayashi, Keiko, Isoe, Toshiyuki, Hatanaka, Yutaka, Tsuda, Hitoshi, Morinaga, Shojiroh, Matsuno, Yoshihiro, Dosaka-Akita, Hirotoshi

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Safety and efficacy of amnion-derived mesenchymal stem cells (AM01) in patients with steroid-refractory acute graft-versus-host disease after allogeneic haematopoietic stem cell tr... von Yamahara, Kenichi, Hamada, Akiko, Soma, Toshihiro, Okamoto, Rika, Okada, Masaya, Yoshihara, Satoshi, Yoshihara, Kyoko, Ikegame, Kazuhiro, Tamaki, Hiroya, Kaida, Katsuji, Inoue, Takayuki, Ohsugi, Yuko, Nishikawa, Hiroki, Hayashi, Hiroshi, Ito, Yoichi M, Iijima, Hiroaki, Ohnishi, Shunsuke, Hashimoto, Daigo, Isoe, Toshiyuki, Teshima, Takanori, Ogawa, Hiroyasu, Sato, Norihiro, Fujimori, Yoshihiro

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Gilvusmycin, a New Antitumor Antibiotic Related to CC-1065 von TOKORO, YUSUKE, ISOE, TOSHIYUKI, SHINDO, KAZUTOSHI

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Evaluation of amnion-derived mesenchymal stem cells for treatment-resistant moderate Crohn’s disease: study protocol for a phase I/II, dual-centre, open-label, uncontrolled, dose–r... von Otagiri, Shinsuke, Ohnishi, Shunsuke, Miura, Arisa, Hayashi, Hiroshi, Kumagai, Izumi, Ito, Yoichi M, Katsurada, Takehiko, Nakamura, Shiro, Okamoto, Rika, Yamahara, Kenichi, Cho, Kyu Yong, Isoe, Toshiyuki, Sato, Norihiro, Sakamoto, Naoya

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STRUCTURE-ANTITUMOR ACTIVITY RELATIONSHIP OF SEMI-SYNTHETIC SPICAMYCIN ANALOGUES von KAMISHOHARA, MASARU, KAWAI, HIROYUKI, ODAGAWA, ATSUO, ISOE, TOSHIYUKI, MOCHIZUKI, JUN-ICHIRO, UCHIDA, TAKESHI, HAYAKAWA, YOICHI, SETO, HARUO, TSURUO, TAKASHI, OTAKE, NOBORU

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Abstract LB-201: Updated results from a Phase I study of AV-951 (KRN951), a potent and selective VEGFR-1, -2 and -3 tyrosine kinase inhibitor, in patients with advanced solid tumor... von Eskens, Ferry A.l.m., de Jonge, Maja J.a., Esteves, Brooke, Cotreau, Monette, Bhargava, Pankaj, Ryan, John, van Doorn, Leny, Isoe, Toshiyuki, Hayashi, Kunihiko, Ekman, Lena, Burger, Herman, Verweij, Jaap

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Synthesis and structure-activity relationship for new series of 4-phenoxyquinoline derivatives as specific inhibitors of platelet-derived growth factor receptor tyrosine kinase von KUBO, Kazuo, OHYAMA, Shin-Ichi, ISOE, Toshiyuki, NAKAMURA, Kazuhide, IIJIMA, Hiroshi, OSAWA, Tatsushi, IZAWA, Toshio, SHIMIZU, Toshiyuki, TAKAMI, Atsuya, MUROOKA, Hideko, NISHITOBA, Tsuyoshi, KATO, Shinichiro, YAGI, Mikio, KOBAYASHI, Yoshiko, IINUMA, Noriko

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