Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite von KAZUI, Miho, NISHIYA, Yumi, ISHIZUKA, Tomoko, HAGIHARA, Katsunobu, FARID, Nagy A, OKAZAKI, Osamu, IKEDA, Toshihiko, KURIHARA, Atsushi

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Physiologically based pharmacokinetic modelling to predict the clinical effect of CYP3A inhibitors/inducers on esaxerenone pharmacokinetics in healthy subjects and subjects with he... von Watanabe, Akiko, Ishizuka, Tomoko, Yamada, Makiko, Igawa, Yoshiyuki, Shimizu, Takako, Ishizuka, Hitoshi

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Correction to: Physiologically based pharmacokinetic modelling to predict the clinical effect of CYP3A inhibitors/inducers on esaxerenone pharmacokinetics in healthy subjects and s... von Watanabe, Akiko, Ishizuka, Tomoko, Yamada, Makiko, Igawa, Yoshiyuki, Shimizu, Takako, Ishizuka, Hitoshi

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Effects of itraconazole and rifampicin on the single‐dose pharmacokinetics of the nonsteroidal mineralocorticoid receptor blocker esaxerenone in healthy Japanese subjects von Kirigaya, Yoshiaki, Shiramoto, Masanari, Ishizuka, Tomoko, Uchimaru, Hinako, Irie, Shin, Kato, Manabu, Shimizu, Takako, Nakatsu, Takafumi, Nishikawa, Yasuhiro, Ishizuka, Hitoshi

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Critical Impact of Drug-Drug Interactions via Intestinal CYP3A in the Risk Assessment of Weak Perpetrators Using Physiologically Based Pharmacokinetic Models von Yamada, Makiko, Inoue, Shin-ichi, Sugiyama, Daisuke, Nishiya, Yumi, Ishizuka, Tomoko, Watanabe, Akiko, Watanabe, Kengo, Yamashita, Shinji, Watanabe, Nobuaki

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A phase I study of pexidartinib, a colony-stimulating factor 1 receptor inhibitor, in Asian patients with advanced solid tumors von Lee, Jih-Hsiang, Chen, Tom Wei-Wu, Hsu, Chih-Hung, Yen, Yu-Hsin, Yang, James Chih-Hsin, Cheng, Ann-Lii, Sasaki, Shun-ichi, Chiu, LiYin (Lillian), Sugihara, Masahiro, Ishizuka, Tomoko, Oguma, Toshihiro, Tajima, Naoyuki, Lin, Chia-Chi

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Modanifil activates the histaminergic system through the orexinergic neurons von Ishizuka, Tomoko, Murotani, Tomotaka, Yamatodani, Atsushi

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Absolute Bioavailability of Esaxerenone and Food Effects on its Pharmacokinetics After a Single Oral Dose in Healthy Japanese Subjects: An Open-Label Crossover Study von Kurata, Akifumi, Furuie, Hidetoshi, Ishizuka, Tomoko, Nakatsu, Takafumi, Shimizu, Takako, Kato, Manabu, Nishikawa, Yasuhiro, Ishizuka, Hitoshi

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Model‐based assessments of CYP3A‐mediated drug‐drug interaction risk of milademetan von Hong, Ying, Ishizuka, Tomoko, Watanabe, Akiko, Tachibana, Masaya, Lee, Mark, Ishizuka, Hitoshi, LaCreta, Frank, Abutarif, Malaz

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Pharmacokinetic interactions of esaxerenone with amlodipine and digoxin in healthy Japanese subjects von Kirigaya, Yoshiaki, Shiramoto, Masanari, Ishizuka, Tomoko, Uchimaru, Hinako, Irie, Shin, Kato, Manabu, Shimizu, Takako, Nakatsu, Takafumi, Nishikawa, Yasuhiro, Ishizuka, Hitoshi

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Identification of non-P450 enzymes involved in the metabolism of new drugs: Their significance in drug interaction evaluation and prodrug disposition von Nishiya, Yumi, Suzuki, Eiko, Ishizuka, Tomoko, Kazui, Miho, Sakurai, Hidetaka, Nakai, Daisuke

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Language-specific and universal influences in children’s syntactic packaging of Manner and Path: A comparison of English, Japanese, and Turkish von Allen, Shanley, Özyürek, Aslı, Kita, Sotaro, Brown, Amanda, Furman, Reyhan, Ishizuka, Tomoko, Fujii, Mihoko

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Development of Cross-Linguistic Variation in Speech and Gesture: Motion Events in English and Turkish von Özyürek, Aslı, Kita, Sotaro, Allen, Shanley, Brown, Amanda, Furman, Reyhan, Ishizuka, Tomoko

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Efficacy and safety of mirikizumab as induction and maintenance therapy for Japanese patients with moderately to severely active ulcerative colitis: a subgroup analysis of the glob... von Kobayashi, Taku, Matsuoka, Katsuyoshi, Watanabe, Mamoru, Hisamatsu, Tadakazu, Hirai, Fumihito, Milata, Joe, Li, Xingyuan, Morris, Nathan, Arora, Vipin, Ishizuka, Tomoko, Matsuo, Koji, Satoi, Yoichi, Milch, Catherine, Hibi, Toshifumi

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Possible involvement of serotonin 5-HT2 receptor in the regulation of feeding behavior through the histaminergic system von Murotani, Tomotaka, Ishizuka, Tomoko, Isogawa, Yuka, Karashima, Michitaka, Yamatodani, Atsushi

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Human Carboxymethylenebutenolidase as a Bioactivating Hydrolase of Olmesartan Medoxomil in Liver and Intestine von Ishizuka, Tomoko, Fujimori, Izumi, Kato, Mitsunori, Noji-Sakikawa, Chisa, Saito, Motoko, Yoshigae, Yasushi, Kubota, Kazuishi, Kurihara, Atsushi, Izumi, Takashi, Ikeda, Toshihiko, Okazaki, Osamu

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Paraoxonase 1 as a major bioactivating hydrolase for olmesartan medoxomil in human blood circulation: molecular identification and contribution to plasma metabolism von Ishizuka, Tomoko, Fujimori, Izumi, Nishida, Atsuko, Sakurai, Hidetaka, Yoshigae, Yasushi, Nakahara, Kaori, Kurihara, Atsushi, Ikeda, Toshihiko, Izumi, Takashi

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Integrative role of the histaminergic system in feeding and taste perception von Ishizuka, Tomoko, Yamatodani, Atsushi

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High dopamine turnover in the brains of Sandy mice von Murotani, Tomotaka, Ishizuka, Tomoko, Hattori, Satoko, Hashimoto, Ryota, Matsuzaki, Shinsuke, Yamatodani, Atsushi

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Interindividual variability of carboxymethylenebutenolidase homolog, a novel olmesartan medoxomil hydrolase, in the human liver and intestine von Ishizuka, Tomoko, Rozehnal, Veronika, Fischer, Thomas, Kato, Ayako, Endo, Seiko, Yoshigae, Yasushi, Kurihara, Atsushi, Izumi, Takashi

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