Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA von Kato, Kazuki, Omura, Hiroki, Ishitani, Ryuichiro, Nureki, Osamu

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Structural biology of the multidrug and toxic compound extrusion superfamily transporters von Kusakizako, Tsukasa, Miyauchi, Hirotake, Ishitani, Ryuichiro, Nureki, Osamu

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Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9 von Hirano, Seiichi, Nishimasu, Hiroshi, Ishitani, Ryuichiro, Nureki, Osamu

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Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1 von Yamano, Takashi, Zetsche, Bernd, Ishitani, Ryuichiro, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu

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Engineered CRISPR-Cas9 nuclease with expanded targeting space von Nishimasu, Hiroshi, Shi, Xi, Ishiguro, Soh, Gao, Linyi, Hirano, Seiichi, Okazaki, Sae, Noda, Taichi, Abudayyeh, Omar O, Gootenberg, Jonathan S, Mori, Hideto, Oura, Seiya, Holmes, Benjamin, Tanaka, Mamoru, Seki, Motoaki, Hirano, Hisato, Aburatani, Hiroyuki, Ishitani, Ryuichiro, Ikawa, Masahito, Yachie, Nozomu, Zhang, Feng, Nureki, Osamu

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Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1 von Kato, Kazuki, Nishimasu, Hiroshi, Oikawa, Daisuke, Hirano, Seiichi, Hirano, Hisato, Kasuya, Go, Ishitani, Ryuichiro, Tokunaga, Fuminori, Nureki, Osamu

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Towards universal neural network potential for material discovery applicable to arbitrary combination of 45 elements von Takamoto, So, Shinagawa, Chikashi, Motoki, Daisuke, Nakago, Kosuke, Li, Wenwen, Kurata, Iori, Watanabe, Taku, Yayama, Yoshihiro, Iriguchi, Hiroki, Asano, Yusuke, Onodera, Tasuku, Ishii, Takafumi, Kudo, Takao, Ono, Hideki, Sawada, Ryohto, Ishitani, Ryuichiro, Ong, Marc, Yamaguchi, Taiki, Kataoka, Toshiki, Hayashi, Akihide, Charoenphakdee, Nontawat, Ibuka, Takeshi

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Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1 von Nishimasu, Hiroshi, Yamano, Takashi, Gao, Linyi, Zhang, Feng, Ishitani, Ryuichiro, Nureki, Osamu

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Molecular Design Method Using a Reversible Tree Representation of Chemical Compounds and Deep Reinforcement Learning von Ishitani, Ryuichiro, Kataoka, Toshiki, Rikimaru, Kentaro

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Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc von Lee, Yongchan, Wiriyasermkul, Pattama, Jin, Chunhuan, Quan, Lili, Ohgaki, Ryuichi, Okuda, Suguru, Kusakizako, Tsukasa, Nishizawa, Tomohiro, Oda, Kazumasa, Ishitani, Ryuichiro, Yokoyama, Takeshi, Nakane, Takanori, Shirouzu, Mikako, Endou, Hitoshi, Nagamori, Shushi, Kanai, Yoshikatsu, Nureki, Osamu

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Structure and Engineering of Francisella novicida Cas9 von Hirano, Hisato, Gootenberg, Jonathan S., Horii, Takuro, Abudayyeh, Omar O., Kimura, Mika, Hsu, Patrick D., Nakane, Takanori, Ishitani, Ryuichiro, Hatada, Izuho, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu

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Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9 von Hirano, Seiichi, Abudayyeh, Omar O., Gootenberg, Jonathan S., Horii, Takuro, Ishitani, Ryuichiro, Hatada, Izuho, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu

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Crystal structure of Drosophila Piwi von Yamaguchi, Sonomi, Oe, Akira, Nishida, Kazumichi M., Yamashita, Keitaro, Kajiya, Asako, Hirano, Seiichi, Matsumoto, Naoki, Dohmae, Naoshi, Ishitani, Ryuichiro, Saito, Kuniaki, Siomi, Haruhiko, Nishimasu, Hiroshi, Siomi, Mikiko C., Nureki, Osamu

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Lateral access mechanism of LPA receptor probed by molecular dynamics simulation von Suenaga, Rieko, Takemoto, Mizuki, Inoue, Asuka, Ishitani, Ryuichiro, Nureki, Osamu

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Structural basis for the facilitative diffusion mechanism by SemiSWEET transporter von Lee, Yongchan, Nishizawa, Tomohiro, Yamashita, Keitaro, Ishitani, Ryuichiro, Nureki, Osamu

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Crystal structure of the channelrhodopsin light-gated cation channel von Kato, Hideaki E., Zhang, Feng, Yizhar, Ofer, Ramakrishnan, Charu, Nishizawa, Tomohiro, Hirata, Kunio, Ito, Jumpei, Aita, Yusuke, Tsukazaki, Tomoya, Hayashi, Shigehiko, Hegemann, Peter, Maturana, Andrés D., Ishitani, Ryuichiro, Deisseroth, Karl, Nureki, Osamu

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Structure and function of Zucchini endoribonuclease in piRNA biogenesis von Nishimasu, Hiroshi, Ishizu, Hirotsugu, Saito, Kuniaki, Fukuhara, Satoshi, Kamatani, Miharu K., Bonnefond, Luc, Matsumoto, Naoki, Nishizawa, Tomohiro, Nakanaga, Keita, Aoki, Junken, Ishitani, Ryuichiro, Siomi, Haruhiko, Siomi, Mikiko C., Nureki, Osamu

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Free Energy Landscape for the Entire Transport Cycle of Triose-Phosphate/Phosphate Translocator von Takemoto, Mizuki, Lee, Yongchan, Ishitani, Ryuichiro, Nureki, Osamu

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Cryo-EM structures of the human volume-regulated anion channel LRRC8 von Kasuya, Go, Nakane, Takanori, Yokoyama, Takeshi, Jia, Yanyan, Inoue, Masato, Watanabe, Kengo, Nakamura, Ryoki, Nishizawa, Tomohiro, Kusakizako, Tsukasa, Tsutsumi, Akihisa, Yanagisawa, Haruaki, Dohmae, Naoshi, Hattori, Motoyuki, Ichijo, Hidenori, Yan, Zhiqiang, Kikkawa, Masahide, Shirouzu, Mikako, Ishitani, Ryuichiro, Nureki, Osamu

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Crystal Structure of Silkworm PIWI-Clade Argonaute Siwi Bound to piRNA von Matsumoto, Naoki, Nishimasu, Hiroshi, Sakakibara, Kazuhiro, Nishida, Kazumichi M., Hirano, Takamasa, Ishitani, Ryuichiro, Siomi, Haruhiko, Siomi, Mikiko C., Nureki, Osamu

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