CDMOs Play a Critical Role in the Biopharmaceutical Ecosystem von Kurata, Hideyuki, Ishino, Tetsuya, Ohshima, Yasuhiro, Yohda, Masafumi

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Engineering a Monomeric Fc Domain Modality by N-Glycosylation for the Half-life Extension of Biotherapeutics von Ishino, Tetsuya, Wang, Mengmeng, Mosyak, Lidia, Tam, Amy, Duan, Weili, Svenson, Kristine, Joyce, Alison, O'Hara, Denise M., Lin, Laura, Somers, William S., Kriz, Ronald

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Faster in vivo clearance of human embryonic kidney than Chinese hamster ovary cell derived protein: Role of glycan mediated clearance von Wang, Mengmeng, Ishino, Tetsuya, Joyce, Alison, Tam, Amy, Duan, Weili, Lin, Laura, Somers, William S., Kriz, Ronald, O'Hara, Denise M.

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Structural and Dynamic Features of the MutT Protein in the Recognition of Nucleotides with the Mutagenic 8-Oxoguanine Base von Nakamura, Teruya, Meshitsuka, Sachiko, Kitagawa, Seiju, Abe, Nanase, Yamada, Junichi, Ishino, Tetsuya, Nakano, Hiroaki, Tsuzuki, Teruhisa, Doi, Takefumi, Kobayashi, Yuji, Fujii, Satoshi, Sekiguchi, Mutsuo, Yamagata, Yuriko

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Interleukin-5 Receptor Subunit Oligomerization and Rearrangement Revealed by Fluorescence Resonance Energy Transfer Imaging von Zaks-Zilberman, Meirav, Harrington, Adrian E., Ishino, Tetsuya, Chaiken, Irwin M.

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Solution NMR Structure Investigation for Releasing Mechanism of Neocarzinostatin Chromophore from the Holoprotein von Takashima, Hiroyuki, Yoshida, Takuya, Ishino, Tetsuya, Hasuda, Katsumi, Ohkubo, Tadayasu, Kobayashi, Yuji

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Receptor Epitope Usage by an Interleukin-5 Mimetic Peptide von Ishino, Tetsuya, Urbina, Cecilia, Bhattacharya, Madhushree, Panarello, Dominick, Chaiken, Irwin

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Development of a Novel Long-Acting Antidiabetic FGF21 Mimetic by Targeted Conjugation to a Scaffold Antibody von Huang, Jie, Ishino, Tetsuya, Chen, Gang, Rolzin, Paul, Osothprarop, Trina F., Retting, Kelsey, Li, Lingna, Jin, Ping, Matin, Marla J., Huyghe, Bernard, Talukdar, Saswata, Bradshaw, Curt W., Palanki, Moorthy, Violand, Bernard N., Woodnutt, Gary, Lappe, Rodney W., Ogilvie, Kathleen, Levin, Nancy

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Solution Structure of the Ribosome Recycling Factor from Aquifex aeolicus von Yoshida, Takuya, Uchiyama, Susumu, Nakano, Hiroaki, Kashimori, Hiromasa, Kijima, Hiroyuki, Ohshima, Tamiko, Saihara, Yukari, Ishino, Tetsuya, Shimahara, Hideto, Yoshida, Toshio, Yokose, Kazuteru, Ohkubo, Tadayasu, Kaji, Akira, Kobayashi, Yuji

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Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease von Zhong, Xiaotian, Jagarlapudi, Srinath, Weng, Yan, Ly, Mellisa, Rouse, Jason C., McClure, Kim, Ishino, Tetsuya, Zhang, Yan, Sousa, Eric, Cohen, Justin, Tzvetkova, Boriana, Cote, Kaffa, Scarcelli, John J., Johnson, Keith, Palandra, Joe, Apgar, James R., Yaddanapudi, Suma, Gonzalez-Villalobos, Romer A., Opsahl, Alan C., Lam, Khetemenee, Yao, Qing, Duan, Weili, Sievers, Annette, Zhou, Jing, Ferguson, Darren, D'Antona, Aaron, Zollner, Richard, Zhu, Hongli L., Kriz, Ron, Lin, Laura, Clerin, Valerie

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Multivalent and Flexible PEG-Nitrilotriacetic Acid Derivatives for Non-covalent Protein Pegylation von Mero, Anna, Ishino, Tetsuya, Chaiken, Irwin, Veronese, Francesco M., Pasut, Gianfranco

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Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)‑B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity N... von Kuai, Jun, Mosyak, Lidia, Brooks, Jon, Cain, Michael, Carven, Gregory J, Ogawa, Shinji, Ishino, Tetsuya, Tam, May, Lavallie, Edward R, Yang, Zhiyong, Ponsel, Dirk, Rauchenberger, Robert, Arch, Robert, Pullen, Nick

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Glyco-engineered Long Acting FGF21 Variant with Optimal Pharmaceutical and Pharmacokinetic Properties to Enable Weekly to Twice Monthly Subcutaneous Dosing von Weng, Yan, Ishino, Tetsuya, Sievers, Annette, Talukdar, Saswata, Chabot, Jeffrey R., Tam, Amy, Duan, Weili, Kerns, Kelvin, Sousa, Eric, He, Tao, Logan, Alison, Lee, Darwin, Li, Dongmei, Zhou, Yingjiang, Bernardo, Barbara, Joyce, Alison, Kavosi, Mania, O’Hara, Denise M., Clark, Tracey, Guo, Jie, Giragossian, Craig, Stahl, Mark, Calle, Roberto A., Kriz, Ron, Somers, Will, Lin, Laura

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The Role of Calcium-binding Sites in S-modulin Function von Matsuda, Shinji, Hisatomi, Osamu, Ishino, Tetsuya, Kobayashi, Yuji, Tokunaga, Fumio

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Kinetic Interaction Analysis of Human Interleukin 5 Receptor α Mutants Reveals a Unique Binding Topology and Charge Distribution for Cytokine Recognition von Ishino, Tetsuya, Pasut, Gianfranco, Scibek, Jeffery, Chaiken, Irwin

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Monitoring Ligand‐Dependent IL‐5 Receptor Activation on Cells Using Fluorescence Resonance Energy Transfer (FRET) von Zaks‐Zilberman, Meirav, Harrington, Adrian, Ishino, Tetsuya, Chaiken, Irwin

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A Protein Engineering Approach Differentiates the Functional Importance of Carbohydrate Moieties of Interleukin-5 Receptor α von Ishino, Tetsuya, Economou, Nicoleta J, McFadden, Karyn, Zaks-Zilberman, Meirav, Jost, Monika, Baxter, Sabine, Contarino, Mark R, Harrington, Adrian E, Loll, Patrick J, Pasut, Gianfranco, Lievens, Sam, Tavernier, Jan, Chaiken, Irwin

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Functional Expression and Characterization of Frog Photoreceptor-Specific Calcium-Binding Proteins von Hisatomi, Osamu, Ishino, Tetsuya, Matsuda, Shinji, Yamaguchi, Kouji, Kobayashi, Yuji, Kawamura, Satoru, Tokunaga, Fumio

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Interleukin-5 Receptor Subunit Oligomerization and Rearrangement Revealed by Fluorescence Resonance Energy Transfer ImagingS von Zaks-Zilberman, Meirav, Harrington, Adrian E., Ishino, Tetsuya, Chaiken, Irwin M.

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Slow-dissociation effect of common signaling subunit β on IL5 and GM-CSF receptor assembly von Ishino, Tetsuya, Harrington, Adrian E., Zaks-Zilberman, Meirav, Scibek, Jeffery J., Chaiken, Irwin

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