Buprenorphine - an attractive opioid with underutilized potential in treatment of chronic pain von Khanna, Ish K, Pillarisetti, Sivaram

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1,2-Diarylimidazoles as Potent, Cyclooxygenase-2 Selective, and Orally Active Antiinflammatory Agents von Khanna, Ish K, Weier, Richard M, Yu, Yi, Xu, Xiang D, Koszyk, Francis J, Collins, Paul W, Koboldt, Carol M, Veenhuizen, Amy W, Perkins, William E, Casler, Jacquelen J, Masferrer, Jaime L, Zhang, Yan Y, Gregory, Susan A, Seibert, Karen, Isakson, Peter C

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1,2-Diarylpyrroles as Potent and Selective Inhibitors of Cyclooxygenase-2 von Khanna, Ish K, Weier, Richard M, Yu, Yi, Collins, Paul W, Miyashiro, Julie M, Koboldt, Carol M, Veenhuizen, Amy W, Currie, Jerry L, Seibert, Karen, Isakson, Peter C

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Convergent, parallel synthesis of a series of β-substituted 1,2,4-oxadiazole butanoic acids as potent and selective αvβ3 receptor antagonists von BOYS, Mark L, SCHRETZMAN, Lori A, STENMARK, Heather G, HONGWEI WU, SPANGLER, Dale P, CLARE, Michael, DESAI, Bipin N, KHANNA, Ish K, NGUYEN, Maria N, DUFFIN, Tiffany, WAYNE ENGLEMAN, V, FINN, Mary Beth, CHANDRAKUMAR, Nizal S, FREEMAN, Sandra K, HANNEKE, Melanie L, KEENE, Jeffery L, KLOVER, Jon A, NICKOLS, G. Allen, NICKOLS, Maureen A, STEININGER, Christina N, WESTLIN, Marisa, WESTLIN, William, YU, Yi X, TOLLEFSON, Michael B, YAPING WANG, DALTON, Christopher R, NORRING, Sarah A, MOHLER, Scott B, DOWNS, Victoria L, PENNING, Thomas D, RUSSELL, Mark A, WENDT, John A, CHEN, Barbara B

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Discovery of + (2 -{4 -[2 -(5,6,7,8 -tetrahydro -1,8 -naphthyridin -2-yl )ethoxy ]phenyl} -cyclopropyl )acetic acid as potent and selective αvβ3 inhibitor : Design, synthesis, and... von NAGARAJAN, Srinivasan R, LU, Hwang-Fun, KEENE, Jeffery L, DUFFIN, Tiffany, ENGLEMAN, V. Wayne, FINN, Mary B, FREEMAN, Sandra K, KLOVER, Jon A, NICKOLS, G. Alan, NICKOLS, Maureen A, SHANNON, Kristen E, STEININGER, Christina A, GASIECKI, Alan F, WESTLIN, William F, WESTLIN, Marisa M, WILLIAMS, Melanie L, KHANNA, Ish K, PARIKH, Mihir D, DESAI, Bipinchandra N, ROGERS, Thomas E, CLARE, Michael, CHEN, Barbara B, RUSSELL, Mark A

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Facile, Regioselective Syntheses of N-Alkylated 2,3-Diaminopyridines and Imidazo[4,5-b]pyridines von Khanna, Ish K, Weier, Richard M, Lentz, Kirk T, Swenton, Lydia, Lankin, David C

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Selective Cyclooxygenase-2 Inhibitors:  Heteroaryl Modified 1,2-Diarylimidazoles Are Potent, Orally Active Antiinflammatory Agents von Khanna, Ish K, Yu, Yi, Huff, Renee M, Weier, Richard M, Xu, Xiangdong, Koszyk, Francis J, Collins, Paul W, Cogburn, J. Nita, Isakson, Peter C, Koboldt, Carol M, Masferrer, Jaime L, Perkins, William E, Seibert, Karen, Veenhuizen, Amy W, Yuan, Jinhua, Yang, Dai-Chang, Zhang, Yan Y

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Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective alphavbeta3 inhibitor: design, synthesis, and optimi... von Nagarajan, Srinivasan R, Lu, Hwang-Fun, Gasiecki, Alan F, Khanna, Ish K, Parikh, Mihir D, Desai, Bipinchandra N, Rogers, Thomas E, Clare, Michael, Chen, Barbara B, Russell, Mark A, Keene, Jeffery L, Duffin, Tiffany, Engleman, V Wayne, Finn, Mary B, Freeman, Sandra K, Klover, Jon A, Nickols, G Alan, Nickols, Maureen A, Shannon, Kristen E, Steininger, Christina A, Westlin, William F, Westlin, Marisa M, Williams, Melanie L

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Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective α vβ 3 inhibitor: Design, synthesis, and optimizatio... von Nagarajan, Srinivasan R., Lu, Hwang-Fun, Gasiecki, Alan F., Khanna, Ish K., Parikh, Mihir D., Desai, Bipinchandra N., Rogers, Thomas E., Clare, Michael, Chen, Barbara B., Russell, Mark A., Keene, Jeffery L., Duffin, Tiffany, Engleman, V. Wayne, Finn, Mary B., Freeman, Sandra K., Klover, Jon A., Nickols, G. Alan, Nickols, Maureen A., Shannon, Kristen E., Steininger, Christina A., Westlin, William F., Westlin, Marisa M., Williams, Melanie L.

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Convergent, parallel synthesis of a series of beta-substituted 1,2,4-oxadiazole butanoic acids as potent and selective alpha(v)beta3 receptor antagonists von Boys, Mark L, Schretzman, Lori A, Chandrakumar, Nizal S, Tollefson, Michael B, Mohler, Scott B, Downs, Victoria L, Penning, Thomas D, Russell, Mark A, Wendt, John A, Chen, Barbara B, Stenmark, Heather G, Wu, Hongwei, Spangler, Dale P, Clare, Michael, Desai, Bipin N, Khanna, Ish K, Nguyen, Maria N, Duffin, Tiffany, Engleman, V Wayne, Finn, Mary Beth, Freeman, Sandra K, Hanneke, Melanie L, Keene, Jeffery L, Klover, Jon A, Nickols, G Allen, Nickols, Maureen A, Steininger, Christina N, Westlin, Marisa, Westlin, William, Yu, Yi X, Wang, Yaping, Dalton, Christopher R, Norring, Sarah A

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Convergent, parallel synthesis of a series of beta -substituted 1,2,4- oxadiazole butanoic acids as potent and selective alpha sub(v) beta sub(3) receptor antagonists von Boys, Mark L, Schretzman, Lori A, Chandrakumar, Nizal S, Tollefson, Michael B, Mohler, Scott B, Downs, Victoria L, Penning, Thomas D, Russell, Mark A, Wendt, John A, Chen, Barbara B, Stenmark, Heather G, Wu, Hongwei, Spangler, Dale P, Clare, Michael, Desai, Bipin N, Khanna, Ish K, Nguyen, Maria N, Duffin, Tiffany, Engleman, VWayne, Finn, Mary Beth, Freeman, Sandra K, Hanneke, Melanie L, Keene, Jeffery L, Klover, Jon A, Nickols, GAllen, Nickols, Maureen A, Steininger, Christina N, Westlin, Marisa, Westlin, William, Yu, Yi X, Wang, Yaping, Dalton, Christopher R, Norring, Sarah A

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Convergent, parallel synthesis of a series of β-substituted 1,2,4-oxadiazole butanoic acids as potent and selective α vβ 3 receptor antagonists von Boys, Mark L., Schretzman, Lori A., Chandrakumar, Nizal S., Tollefson, Michael B., Mohler, Scott B., Downs, Victoria L., Penning, Thomas D., Russell, Mark A., Wendt, John A., Chen, Barbara B., Stenmark, Heather G., Wu, Hongwei, Spangler, Dale P., Clare, Michael, Desai, Bipin N., Khanna, Ish K., Nguyen, Maria N., Duffin, Tiffany, Engleman, V. Wayne, Finn, Mary Beth, Freeman, Sandra K., Hanneke, Melanie L., Keene, Jeffery L., Klover, Jon A., Nickols, G. Allen, Nickols, Maureen A., Steininger, Christina N., Westlin, Marisa, Westlin, William, Yu, Yi X., Wang, Yaping, Dalton, Christopher R., Norring, Sarah A.

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Regiospecific addition of Grignard reagents to the 4-position of activated imidazo[4,5-c]pyridine. A convenient method for the synthesis of 4-alkyl(ary von Khanna, Ish K., Weier, Richard M.

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The synthesis of 1,5-dideoxy-1,5-(alkyl)imino-2-C-methyl- d-glucitols von Khanna, Ish K., Weier, Richard M., Julien, Janet, Mueller, Richard A., Lankin, David C., Swenton, Lydia

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The mild and selective N-debenzylation of tertiary alkylamines using β-trimethylsilylethyl chloroformate von Campbell, Arthur L., Pilipauskas, Daniel R., Khanna, Ish K., Rhodes, R.Allen

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METHODS AND COMPOSITIONS FOR THE TREATMENT OF INFLAMMATION, OBESITY AND RELATED METABOLIC DISORDERS von REDDY, DUMBALA SRINIVAS, KHANNA, ISH, K, BHUNIYA, DEBNATH, SAXENA, UDAY, PILLARISETTI, SIVARAM, PADMALAYAM, INDIRA

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METHODS AND COMPOSITIONS FOR THE TREATMENT OF INFLAMMATION, OBESITY AND RELATED METABOLIC DISORDERS von REDDY, DUMBALA SRINIVAS, KHANNA, ISH, K, BHUNIYA, DEBNATH, SAXENA, UDAY, PILLARISETTI, SIVARAM, PADMALAYAM, INDIRA

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Nucleophilic Opening of N-Carboalkoxy-2,3-anhydro-1-deoxymannojirimycin. A Useful Method for the Syntheses of 2-, 3- and 2,3-Disubstituted 1-Deoxynojirimycin Analogs von Khanna, Ish K., Koszyk, Francis J., Stealey, Michael A., Weier, Richard M., Julien, Janet, Mueller, Richard A., Rao, Shashidhar N., Swenton, Lydia, Getman, Daniel P., DeCrescenzo, Gary A., Heintz, Robert M.

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SUBSTITUTED BENZENESULFONAMIDE DERIVATIVES AS PRODRUGS OF COX-2 INHIBITORS von GRANETO, Matthew J, WEIER, Richard M, MALECHA, James W, NAGARAJAN, Srinivasan, KHANNA, Ish K, TALLEY, John J, CARTER, Jeffrey, BERTENSHAW, Stephen, XU, Xiangdong, ROGIER, Donald J, Jr, LI, Jinglin, BROWN, David L, PENNING, Thomas D

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Total synthesis of 4-Demethoxy-8-nordaunomycinone von Khanna, Ish K., Mitscher, L.A.

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