Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study von Knight, Stephen R, Holden, Karl A, Merson, Laura, Russell, Clark D, Solomon, Tom, Carson, Gail, Olliaro, Piero, Semple, Malcolm G, Alex, Beatrice, Bach, Benjamin, Dunning, Jake, da Silva Filipe, Ana, Horby, Peter W, Law, Andrew, Price, Nicholas, Rambaut, Andrew, Robertson, David L, Scott, Janet T, de Silva, Thushan, Sigfrid, Louise, Tedder, Richard S, Thwaites, Ryan S, Turtle, Lance CW, Andrikopoulos, Petros, Liggi, Sonia, Sands, Caroline, Fairfield, Cameron J, Shaw, Catherine A, Dalton, Jo, Girvan, Michelle, Hendry, Ross, Greenhalf, William, McDonald, Sarah E, Booth, Laura, Catterall, Benjamin WA, Clarke, Emily A, Dincarslan, Oslem, Dyer, Philip, Gunning, Philip, Hartley, Catherine, Jensen, Rebecca L, Jones, Christopher B, Khandaker, Shadia, Lefteri, Daniella, Livoti, Lucia A, Middleton, Joanna, Reynolds, Will, Ridley, P. Matthew, Shaw, Victoria E, Tanianis-Hughes, Jolanta, Trochu, Erwan, Flaherty, Lisa, Massey, Hannah, Aldera, Erin L., Alegria, Ana, Barnass, Stella, Barrett, Nicholas, Basude, Sneha, Baxter, David, Beadsworth, Michael, Best, Nicola, Burden, Tom, Chukkambotla, Srikanth, Cutino-Moguel, Maria-Teresa, Douthwaite, Sam, Fullerton, Duncan, Garg, Atul, Hawcutt, Daniel B, Jennings, Paul, Kaliappan, Agilan, Kasipandian, Vidya, Koduri, Gouri, Laird, Steven, Leiner, Tamas, Little, Jeff, McEwen, Ruth, Morris, Craig, Moses, Samuel, Norris, Lillian, Panchatsharam, Selva, Pattison, Natalie, Peters, Mark, Price, David, Prout, Rachel, Richardson, Neil, Rousseau, Guy, Ryan, Brendan, Sharma, Anil, Stambach, Tom, Stewart, Richard, Thompson, Robert, Tridente, Ascanio, Vuylsteke, Alan, Waddy, Sam, Wake, Rachel, Wilson, Lawrence, Wiselka, Martin, Wootton, Daniel G, Workman, Andrew, Young, Peter

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Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID‐19 von Siggins, Matthew K., Davies, Kate, Fellows, Rosie, Thwaites, Ryan S., Baillie, J. Kenneth, Semple, Malcolm G., Openshaw, Peter J. M., Zelek, Wioleta M., Harris, Claire L., Morgan, B. Paul

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Genetic mechanisms of critical illness in COVID-19 von Pairo-Castineira, Erola, Clohisey, Sara, Klaric, Lucija, Bretherick, Andrew D., Rawlik, Konrad, Pasko, Dorota, Walker, Susan, Parkinson, Nick, Fourman, Max Head, Russell, Clark D., Furniss, James, Richmond, Anne, Gountouna, Elvina, Wrobel, Nicola, Harrison, David, Wang, Bo, Wu, Yang, Meynert, Alison, Griffiths, Fiona, Oosthuyzen, Wilna, Kousathanas, Athanasios, Moutsianas, Loukas, Yang, Zhijian, Zhai, Ranran, Zheng, Chenqing, Grimes, Graeme, Beale, Rupert, Millar, Jonathan, Shih, Barbara, Keating, Sean, Zechner, Marie, Haley, Chris, Porteous, David J., Hayward, Caroline, Yang, Jian, Knight, Julian, Summers, Charlotte, Shankar-Hari, Manu, Klenerman, Paul, Turtle, Lance, Ho, Antonia, Moore, Shona C., Hinds, Charles, Horby, Peter, Nichol, Alistair, Maslove, David, Ling, Lowell, McAuley, Danny, Montgomery, Hugh, Walsh, Timothy, Pereira, Alexandre C., Renieri, Alessandra, Shen, Xia, Ponting, Chris P., Fawkes, Angie, Tenesa, Albert, Caulfield, Mark, Scott, Richard, Rowan, Kathy, Murphy, Lee, Openshaw, Peter J. M., Semple, Malcolm G., Law, Andrew, Vitart, Veronique, Wilson, James F., Baillie, J. Kenneth

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Fewer COVID‐19 Neurological Complications with Dexamethasone and Remdesivir von Grundmann, Alexander, Wu, Chieh‐Hsi, Hardwick, Marc, Baillie, J. Kenneth, Openshaw, Peter J M, Semple, Malcolm G., Böhning, Dankmar, Pett, Sarah, Michael, Benedict D., Thomas, Rhys H., Galea, Ian

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Mapping of SARS-CoV-2 IgM and IgG in gingival crevicular fluid: Antibody dynamics and linkage to severity of COVID-19 in hospital inpatients von Ijaz, Samreen, Dicks, Steve, Jegatheesan, Keerthana, Parker, Eleanor, Katsanovskaja, Ksenia, Vink, Elen, McClure, Myra O., Shute, J., Hope, Joshua, Cook, Nicola, Cherepanov, Peter, Turtle, Lance, Paxton, William A., Pollakis, Georgios, Ho, Antonia, Openshaw, Peter J.M., Baillie, J. Kenneth, Semple, Malcolm G., Tedder, Richard S.

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Comparison of UK paediatric SARS-CoV-2 admissions across the first and second pandemic waves von Swann, Olivia V., Pollock, Louisa, Holden, Karl A., Munro, Alasdair P. S., Bennett, Aisleen, Williams, Thomas C., Turtle, Lance, Fairfield, Cameron J., Drake, Thomas M., Faust, Saul N., Sinha, Ian P., Roland, Damian, Whittaker, Elizabeth, Ladhani, Shamez N., Nguyen-Van-Tam, Jonathan S., Girvan, Michelle, Donohue, Chloe, Donegan, Cara, Spencer, Rebecca G., Hardwick, Hayley E., Openshaw, Peter J. M., Baillie, J. Kenneth, Harrison, Ewen M., Docherty, Annemarie B., Semple, Malcolm G.

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Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study von Docherty, Annemarie B, Harrison, Ewen M, Green, Christopher A, Hardwick, Hayley E, Pius, Riinu, Norman, Lisa, Holden, Karl A, Read, Jonathan M, Dondelinger, Frank, Carson, Gail, Merson, Laura, Lee, James, Plotkin, Daniel, Sigfrid, Louise, Halpin, Sophie, Jackson, Clare, Gamble, Carrol, Horby, Peter W, Nguyen-Van-Tam, Jonathan S, Ho, Antonia, Russell, Clark D, Dunning, Jake, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G

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Features of 20133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study von Docherty, Annemarie B., Harrison, Ewen M., Green, Christopher A., Hardwick, Hayley E., Pius, Riinu, Norman, Lisa, Holden, Karl A., Read, Jonathan M., Dondelinger, Frank, Carson, Gail, Merson, Laura, Lee, James, Plotkin, Daniel, Sigfrid, Louise, Halpin, Sophie, Jackson, Clare, Gamble, Carrol, Horby, Peter W., Nguyen-Van-Tam, Jonathan S., Ho, Antonia, Russell, Clark D., Dunning, Jake, Openshaw, Peter Jm, Baillie, J. Kenneth, Semple, Malcolm G.

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Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score von Knight, Stephen R, Ho, Antonia, Pius, Riinu, Buchan, Iain, Carson, Gail, Drake, Thomas M, Dunning, Jake, Fairfield, Cameron J, Gamble, Carrol, Green, Christopher A, Gupta, Rishi, Halpin, Sophie, Hardwick, Hayley E, Holden, Karl A, Horby, Peter W, Jackson, Clare, Mclean, Kenneth A, Merson, Laura, Nguyen-Van-Tam, Jonathan S, Norman, Lisa, Noursadeghi, Mahdad, Olliaro, Piero L, Pritchard, Mark G, Russell, Clark D, Shaw, Catherine A, Sheikh, Aziz, Solomon, Tom, Sudlow, Cathie, Swann, Olivia V, Turtle, Lance CW, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G, Docherty, Annemarie B, Harrison, Ewen M

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Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study von Halpin, Sophie, Donohue, Chloe, Ladhani, Shamez, Horby, Peter W, Docherty, Annemarie B, Semple, Malcolm G, Openshaw, Peter J M, Bach, Benjamin, Chand, Meera, Harrison, Ewen M, Hiscox, Julian A, Horby, Peter W, Klenerman, Paul, Law, Andrew, Moore, Shona C, Palmarini, Massimo, Russell, Clark D, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Thomson, Emma C, Oosthuyzen, Wilna, Norman, Lisa, Pius, Riinu, Mclean, Kenneth A, Saviciute, Egle, Leeming, Gary, Hendry, Ross, Greenhalf, William, Ahmed, Katie A, Asiimwe, Innocent G, Brennan, Benjamin, Catterall, Benjamin WA, Clark, Jordan J, Cole, Sarah, Cox, Helen, Elliott, Angela, Foster, Terry, Greenhalf, Willliam, Jones, Trevor R, Murphy, Ellen G, Small, Benjamin, Subramaniam, Krishanthi S, Tanianis, Jolanta, Trochu, Erwan, van Tonder, Libby, Wilcock, Eve, Agranoff, Daniel, Angus, Brian, Atkinson, Dougal, Barlow, Gavin, Barrett, Nicholas, Bassford, Christopher, Beadsworth, Michael, Best, Nicola, Burden, Tom, Chukkambotla, Srikanth, Cupitt, Jason, Dark, Paul, Dushianthan, Ahilanadan, Dyer, Tristan, Evans, Cariad, Fegan, Christopher, Finn, Adam, Fullerton, Duncan, Goldsmith, Arthur, Hardy, Elaine, Havalda, Peter, Holme, Anita, Kendall, Jason, Kerrison, Caroline, Larkin, Susan, Leiner, Tamas, Lillie, Patrick, MacNaughton, Emily, McCullough, Katherine, Moore, Elinoor, Morgan, Patrick, Morris, Craig, Nelson, Mark, Panchatsharam, Selva, Pintus, Stefania, Prout, Rachel, Rousseau, Guy, Ryan, Brendan, Saluja, Taranprit, Shanmuga, Prad, Sharma, Anil, Sizer, Jeremy, Smith, Richard, Snelson, Catherine, Spittle, Nick, Stambach, Tom, Tridente, Ascanio, Ustianowski, Andrew, Waddy, Sam, Whittaker, Paul, Williams, Martin, Wiselka, Martin, Young, Peter

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SARS-CoV-2 co-infection with influenza viruses, respiratory syncytial virus, or adenoviruses von Swets, Maaike C, Russell, Clark D, Harrison, Ewen M, Docherty, Annemarie B, Lone, Nazir, Girvan, Michelle, Hardwick, Hayley E, Visser, Leonardus G, Openshaw, Peter J M, Groeneveld, Geert H, Semple, Malcolm G, Baillie, J Kenneth

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Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity von Thomson, Emma C., Rosen, Laura E., Shepherd, James G., Spreafico, Roberto, da Silva Filipe, Ana, Wojcechowskyj, Jason A., Davis, Chris, Piccoli, Luca, Pascall, David J., Dillen, Josh, Lytras, Spyros, Czudnochowski, Nadine, Shah, Rajiv, Meury, Marcel, Jesudason, Natasha, De Marco, Anna, Li, Kathy, Bassi, Jessica, O’Toole, Aine, Pinto, Dora, Colquhoun, Rachel M., Culap, Katja, Jackson, Ben, Zatta, Fabrizia, Rambaut, Andrew, Jaconi, Stefano, Sreenu, Vattipally B., Nix, Jay, Zhang, Ivy, Jarrett, Ruth F., Glass, William G., Beltramello, Martina, Nomikou, Kyriaki, Pizzuto, Matteo, Tong, Lily, Cameroni, Elisabetta, Croll, Tristan I., Johnson, Natasha, Di Iulio, Julia, Wickenhagen, Arthur, Ceschi, Alessandro, Harbison, Aoife M., Mair, Daniel, Ferrari, Paolo, Smollett, Katherine, Sallusto, Federica, Carmichael, Stephen, Garzoni, Christian, Nichols, Jenna, Galli, Massimo, Hughes, Joseph, Riva, Agostino, Ho, Antonia, Schiuma, Marco, Semple, Malcolm G., Openshaw, Peter J.M., Fadda, Elisa, Baillie, J. Kenneth, Chodera, John D., Rihn, Suzannah J., Lycett, Samantha J., Virgin, Herbert W., Telenti, Amalio, Corti, Davide, Robertson, David L., Snell, Gyorgy

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A prenylated dsRNA sensor protects against severe COVID-19 von Wickenhagen, Arthur, Sugrue, Elena, Lytras, Spyros, Kuchi, Srikeerthana, Noerenberg, Marko, Turnbull, Matthew L., Loney, Colin, Herder, Vanessa, Allan, Jay, Jarmson, Innes, Cameron-Ruiz, Natalia, Varjak, Margus, Pinto, Rute M., Lee, Jeffrey Y., Iselin, Louisa, Palmalux, Natasha, Stewart, Douglas G., Swingler, Simon, Greenwood, Edward J. D., Crozier, Thomas W. M., Gu, Quan, Davies, Emma L., Clohisey, Sara, Wang, Bo, Maranhao Costa, Fabio Trindade, Santana, Monique Freire, de Lima Ferreira, Luiz Carlos, Murphy, Lee, Fawkes, Angie, Meynert, Alison, Grimes, Graeme, Filho, Joao Luiz Da Silva, Marti, Matthias, Hughes, Joseph, Stanton, Richard J., Wang, Eddie C. Y., Ho, Antonia, Davis, Ilan, Jarrett, Ruth F., Castello, Alfredo, Robertson, David L., Semple, Malcolm G., Openshaw, Peter J. M., Palmarini, Massimo, Lehner, Paul J., Baillie, J. Kenneth, Rihn, Suzannah J., Wilson, Sam J.

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Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease An International Multicenter Study von Drake, Thomas M., Docherty, Annemarie B., Harrison, Ewen M., Quint, Jennifer K., Adamali, Huzaifa, Agnew, Sarah, Babu, Suresh, Barber, Christopher M., Barratt, Shaney, Bendstrup, Elisabeth, Bianchi, Stephen, Villegas, Diego Castillo, Chaudhuri, Nazia, Chua, Felix, Coker, Robina, Chang, William, Crawshaw, Anjali, Crowley, Louise E., Dosanjh, Davinder, Fiddler, Christine A., Forrest, Ian A., George, Peter M., Gibbons, Michael A., Groom, Katherine, Haney, Sarah, Hart, Simon P., Heiden, Emily, Henry, Michael, Ho, Ling-Pei, Hoyles, Rachel K., Hutchinson, John, Hurley, Killian, Jones, Mark, Jones, Steve, Kokosi, Maria, Kreuter, Michael, MacKay, Laura S., Mahendran, Siva, Margaritopoulos, George, Molina-Molina, Maria, Molyneaux, Philip L., O'Brien, Aiden, O'Reilly, Katherine, Packham, Alice, Parfrey, Helen, Poletti, Venerino, Porter, Joanna C., Renzoni, Elisabetta, Rivera-Ortega, Pilar, Russell, Anne-Marie, Saini, Gauri, Spencer, Lisa G., Stella, Giulia M., Stone, Helen, Sturney, Sharon, Thickett, David, Thillai, Muhunthan, Wallis, Tim, Ward, Katie, Wells, Athol U., West, Alex, Wickremasinghe, Melissa, Woodhead, Felix, Hearson, Glenn, Howard, Lucy, Baillie, J. Kenneth, Openshaw, Peter J. M., Semple, Malcolm G., Stewart, Iain, Jenkins, R. Gisli

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Hospital-acquired SARS-CoV-2 infection in the UK's first COVID-19 pandemic wave von Read, Jonathan M, Green, Chris A, Harrison, Ewen M, Docherty, Annemarie B, Funk, Sebastian, Harrison, Janet, Girvan, Michelle, Hardwick, Hayley E, Turtle, Lance, Dunning, Jake, Nguyen-Van-Tam, Jonathan S, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G

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Estimating distribution of length of stay in a multi-state model conditional on the pathway, with an application to patients hospitalised with Covid-19 von Keogh, Ruth H., Diaz-Ordaz, Karla, Jewell, Nicholas P., Semple, Malcolm G., de Wreede, Liesbeth C., Putter, Hein

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Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, pr... von Fairfield, Cameron J, Drake, Thomas M, Sigfrid, Louise, Docherty, Annemarie B, Girvan, Michelle, Dunning, Jake, Openshaw, Peter J M, Openshaw, Peter JM, Bach, Benjamin, Chand, Meera, Harrison, Ewen M, Hiscox, Julian A, Law, Andrew, Merson, Laura, Moore, Shona C, Russell, Clark D, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Tedder, Richard S, Palmieri, Carlo, Knight, Stephen R, Shaw, Catherine A, Marsh, Laura, Shaw, Victoria, McDonald, Sarah E, Keating, Seán, Armstrong, Jane A, Ashworth, Milton, Booth, Laura, Brennan, Benjamin, Bullock, Katie, Cooper, Louise, Davis, Christopher, Dincarslan, Oslem, Dunn, Chris, Evans, Anthony, Garcia-Dorival, Isabel, Jones, Christopher B, Khandaker, Shadia, Lant, Suzannah, Lavelle-Langham, Lara, Lefteri, Daniella, Lett, Lauren, Livoti, Lucia A, Mancini, Maria, McLauchlan, John, Murphy, Ellen G, Penrice-Randal, Rebekah, Pilgrim, Jack, Small, Benjamin, Subramaniam, Krishanthi S, Tanianis-Hughes, Jolanta, van Tonder, Libby, Wilcock, Eve, Flaherty, Lisa, MacLean, Alan, Agranoff, Daniel, Aldera, Erin L., Alegria, Ana, Bari, Shahedal, Barlow, Gavin, Barnass, Stella, Basude, Sneha, Chadwick, David, Chee, Nigel, Chukkambotla, Srikanth, Cutino-Moguel, Maria-Teresa, Dark, Paul, Donnison, Phil, Douthwaite, Sam, Dushianthan, Ahilanadan, Eziefula, Chi, Fegan, Chrisopher, Garg, Atul, Hawcutt, Daniel B, Hobrok, Maria, Jennings, Paul, Koduri, Gouri, Laha, Shondipon, Laird, Steven, MacNaughton, Emily, Mankregod, Ravish, Masson, Huw, McCullough, Katherine, Mirfenderesky, Mariyam, Mohandas, Kavya, Morris, Craig, Nagel, Megan, Papakonstantino, Danai, Pintus, Stefania, Singh Pooni, Jagtur, Prout, Rachel, Roberts, Devender, Rose, Alistair, Shawcross, Anna, Tatham, Kate, Vuylsteke, Alan, Whittaker, Paul, Wiselka, Martin

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Plasma steroid concentrations reflect acute disease severity and normalise during recovery in people hospitalised with COVID‐19 von Devine, Kerri, Russell, Clark D., Blanco, Giovanny R., Walker, Brian R., Homer, Natalie Z. M., Denham, Scott G., Simpson, Joanna P., Leavy, Olivia C., Elneima, Omer, McAuley, Hamish J. C., Shikotra, Aarti, Singapuri, Amisha, Sereno, Marco, Saunders, Ruth M., Harris, Victoria C., Houchen‐Wolloff, Linzy, Greening, Neil J., Lone, Nazir I., Thorpe, Mathew, Greenhalf, William, Chalmers, James D., Ho, Ling‐Pei, Horsley, Alex, Marks, Michael, Raman, Betty, Moore, Shona C., Dunning, Jake, Semple, Malcolm G., Andrew, Ruth, Wain, Louise V., Evans, Rachael A., Brightling, Christopher E., Kenneth Baillie, John, Reynolds, Rebecca M.

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Outcome of COVID-19 in hospitalised immunocompromised patients: An analysis of the WHO ISARIC CCP-UK prospective cohort study von Turtle, Lance, Thorpe, Mathew, Drake, Thomas M, Swets, Maaike, Palmieri, Carlo, Russell, Clark D, Ho, Antonia, Aston, Stephen, Wootton, Daniel G, Richter, Alex, de Silva, Thushan I, Hardwick, Hayley E, Leeming, Gary, Law, Andy, Openshaw, Peter J M, Harrison, Ewen M, Baillie, J Kenneth, Semple, Malcolm G, Docherty, Annemarie B

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Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study: a prospective, multicentre cohort study von Sullivan, Michael K, Lees, Jennifer S, Drake, Thomas M, Docherty, Annemarie B, Oates, Georgia, Hardwick, Hayley E, Russell, Clark D, Merson, Laura, Dunning, Jake, Nguyen-Van-Tam, Jonathan S, Openshaw, Peter, Harrison, Ewen M, Baillie, J Kenneth, Semple, Malcolm G, Ho, Antonia, Mark, Patrick B

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