Synthetic Nanoparticles for Vaccines and Immunotherapy von Irvine, Darrell J, Hanson, Melissa C, Rakhra, Kavya, Tokatlian, Talar

Volltext

Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity von Zhang, Yuan, Li, Na, Suh, Heikyung, Irvine, Darrell J.

Volltext

Roles for Innate Immunity in Combination Immunotherapies von Moynihan, Kelly D, Irvine, Darrell J

Volltext

Engineering Nano- and Microparticles to Tune Immunity von Moon, James J., Huang, Bonnie, Irvine, Darrell J.

Volltext

Role of nanoscale antigen organization on B-cell activation probed using DNA origami von Veneziano, Rémi, Moyer, Tyson J., Stone, Matthew B., Wamhoff, Eike-Christian, Read, Benjamin J., Mukherjee, Sayak, Shepherd, Tyson R., Das, Jayajit, Schief, William R., Irvine, Darrell J., Bathe, Mark

Volltext

Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo von Kato, Yu, Abbott, Robert K., Freeman, Brian L., Haupt, Sonya, Groschel, Bettina, Silva, Murillo, Menis, Sergey, Irvine, Darrell J., Schief, William R., Crotty, Shane

Volltext

T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity von Schmid, Daniela, Park, Chun Gwon, Hartl, Christina A., Subedi, Nikita, Cartwright, Adam N., Puerto, Regina Bou, Zheng, Yiran, Maiarana, James, Freeman, Gordon J., Wucherpfennig, Kai W., Irvine, Darrell J., Goldberg, Michael S.

Volltext

Structure-based programming of lymph-node targeting in molecular vaccines von Liu, Haipeng, Moynihan, Kelly D., Zheng, Yiran, Szeto, Gregory L., Li, Adrienne V., Huang, Bonnie, Van Egeren, Debra S., Park, Clara, Irvine, Darrell J.

Volltext

Enhancing cell therapies from the outside in: Cell surface engineering using synthetic nanomaterials von Stephan, Matthias T., Irvine, Darrell J.

Volltext

Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants von Hanson, Melissa C, Crespo, Monica P, Abraham, Wuhbet, Moynihan, Kelly D, Szeto, Gregory L, Chen, Stephanie H, Melo, Mariane B, Mueller, Stefanie, Irvine, Darrell J

Volltext

Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy von Kwong, Brandon, Liu, Haipeng, Irvine, Darrell J

Volltext

Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers von Tokatlian, Talar, Read, Benjamin J., Jones, Christopher A., Kulp, Daniel W., Menis, Sergey, Chang, Jason Y. H., Steichen, Jon M., Kumari, Sudha, Allen, Joel D., Dane, Eric L., Liguori, Alessia, Sangesland, Maya, Lingwood, Daniel, Crispin, Max, Schief, William R., Irvine, Darrell J.

Volltext

Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance von Cirelli, Kimberly M., Carnathan, Diane G., Nogal, Bartek, Martin, Jacob T., Rodriguez, Oscar L., Upadhyay, Amit A., Enemuo, Chiamaka A., Gebru, Etse H., Choe, Yury, Viviano, Federico, Nakao, Catherine, Pauthner, Matthias G., Reiss, Samantha, Cottrell, Christopher A., Smith, Melissa L., Bastidas, Raiza, Gibson, William, Wolabaugh, Amber N., Melo, Mariane B., Cossette, Benjamin, Kumar, Venkatesh, Patel, Nirav B., Tokatlian, Talar, Menis, Sergey, Kulp, Daniel W., Burton, Dennis R., Murrell, Ben, Schief, William R., Bosinger, Steven E., Ward, Andrew B., Watson, Corey T., Silvestri, Guido, Irvine, Darrell J., Crotty, Shane

Volltext

High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry von Yang, Yu-Sang Sabrina, Atukorale, Prabhani U., Moynihan, Kelly D., Bekdemir, Ahmet, Rakhra, Kavya, Tang, Li, Stellacci, Francesco, Irvine, Darrell J.

Volltext

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies von Steichen, Jon M., Kulp, Daniel W., Tokatlian, Talar, Escolano, Amelia, Dosenovic, Pia, Stanfield, Robyn L., McCoy, Laura E., Ozorowski, Gabriel, Hu, Xiaozhen, Kalyuzhniy, Oleksandr, Briney, Bryan, Schiffner, Torben, Garces, Fernando, Freund, Natalia T., Gitlin, Alexander D., Menis, Sergey, Georgeson, Erik, Kubitz, Michael, Adachi, Yumiko, Jones, Meaghan, Mutafyan, Andrew A., Yun, Dong Soo, Mayer, Christian T., Ward, Andrew B., Burton, Dennis R., Wilson, Ian A., Irvine, Darrell J., Nussenzweig, Michel C., Schief, William R.

Volltext

Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination von Tam, Hok Hei, Melo, Mariane B., Kang, Myungsun, Pelet, Jeisa M., Ruda, Vera M., Foley, Maria H., Hu, Joyce K., Kumari, Sudha, Crampton, Jordan, Baldeon, Alexis D., Sanders, Rogier W., Moore, John P., Crotty, Shane, Langer, Robert, Anderson, Daniel G., Chakraborty, Arup K., Irvine, Darrell J.

Volltext

In Vitro and in Vivo mRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles von Su, Xingfang, Fricke, Jennifer, Kavanagh, Daniel G, Irvine, Darrell J

Volltext

Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity von Backlund, Coralie M., Holden, Rebecca L., Moynihan, Kelly D., Garafola, Daniel, Farquhar, Charlotte, Mehta, Naveen K., Maiorino, Laura, Pham, Sydney, Iorgulescu, J. Bryan, Reardon, David A., Wu, Catherine J., Pentelute, Bradley L., Irvine, Darrell J.

Volltext

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques von Escolano, Amelia, Gristick, Harry B., Abernathy, Morgan E., Merkenschlager, Julia, Gautam, Rajeev, Oliveira, Thiago Y., Pai, Joy, West, Anthony P., Barnes, Christopher O., Cohen, Alexander A., Wang, Haoqing, Golijanin, Jovana, Yost, Daniel, Keeffe, Jennifer R., Wang, Zijun, Zhao, Peng, Yao, Kai-Hui, Bauer, Jens, Nogueira, Lilian, Gao, Han, Voll, Alisa V., Montefiori, David C., Seaman, Michael S., Gazumyan, Anna, Silva, Murillo, McGuire, Andrew T., Stamatatos, Leonidas, Irvine, Darrell J., Wells, Lance, Martin, Malcolm A., Bjorkman, Pamela J., Nussenzweig, Michel C.

Volltext

Releasable Layer-by-Layer Assembly of Stabilized Lipid Nanocapsules on Microneedles for Enhanced Transcutaneous Vaccine Delivery von DeMuth, Peter C, Moon, James J, Suh, Heikyung, Hammond, Paula T, Irvine, Darrell J

Volltext