HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease von d'Ydewalle, Constantin, Krishnan, Jyothsna, Chiheb, Driss M, Van Damme, Philip, Irobi, Joy, Kozikowski, Alan P, Berghe, Pieter Vanden, Timmerman, Vincent, Robberecht, Wim, Van Den Bosch, Ludo

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A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8 von Bouhy, Delphine, Juneja, Manisha, Katona, Istvan, Holmgren, Anne, Asselbergh, Bob, De Winter, Vicky, Hochepied, Tino, Goossens, Steven, Haigh, Jody J., Libert, Claude, Ceuterick-de Groote, Chantal, Irobi, Joy, Weis, Joachim, Timmerman, Vincent

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Angiogenic Effects of Human Dental Pulp and Bone Marrow-Derived Mesenchymal Stromal Cells and their Extracellular Vesicles von Merckx, Greet, Hosseinkhani, Baharak, Kuypers, Sören, Deville, Sarah, Irobi, Joy, Nelissen, Inge, Michiels, Luc, Lambrichts, Ivo, Bronckaers, Annelies

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Oligodendroglia-derived extracellular vesicles activate autophagy via LC3B/BAG3 to protect against oxidative stress with an enhanced effect for HSPB8 enriched vesicles von Van den Broek, Bram, Wuyts, Charlotte, Sisto, Angela, Pintelon, Isabel, Timmermans, Jean-Pierre, Somers, Veerle, Timmerman, Vincent, Hellings, Niels, Irobi, Joy

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Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy von Jordanova, Albena, Irobi, Joy, Thomas, Florian P, Van Dijck, Patrick, Meerschaert, Kris, Dewil, Maarten, Dierick, Ines, Jacobs, An, De Vriendt, Els, Guergueltcheva, Velina, Rao, Chitharanjan V, Tournev, Ivailo, Gondim, Francisco A A, D'Hooghe, Marc, Van Gerwen, Veerle, Callaerts, Patrick, Van Den Bosch, Ludo, Timmermans, Jean-Pièrre, Robberecht, Wim, Gettemans, Jan, Thevelein, Johan M, De Jonghe, Peter, Kremensky, Ivo, Timmerman, Vincent

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Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy von Evgrafov, Oleg V, Mersiyanova, Irena, Irobi, Joy, Van Den Bosch, Ludo, Dierick, Ines, Leung, Conrad L, Schagina, Olga, Verpoorten, Nathalie, Van Impe, Katrien, Fedotov, Valeriy, Dadali, Elena, Auer-Grumbach, Michaela, Windpassinger, Christian, Wagner, Klaus, Mitrovic, Zoran, Hilton-Jones, David, Talbot, Kevin, Martin, Jean-Jacques, Vasserman, Natalia, Tverskaya, Svetlana, Polyakov, Alexander, Liem, Ronald K H, Gettemans, Jan, Robberecht, Wim, De Jonghe, Peter, Timmerman, Vincent

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DNA/RNA Helicase Gene Mutations in a Form of Juvenile Amyotrophic Lateral Sclerosis (ALS4) von Chen, Ying-Zhang, Bennett, Craig L., Huynh, Huy M., Blair, Ian P., Puls, Imke, Irobi, Joy, Dierick, Ines, Abel, Annette, Kennerson, Marina L., Rabin, Bruce A., Nicholson, Garth A., Auer-Grumbach, Michaela, Wagner, Klaus, De Jonghe, Peter, Griffin, John W., Fischbeck, Kenneth H., Timmerman, Vincent, Cornblath, David R., Chance, Phillip F.

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Charcot–Marie–Tooth causing HSPB1 mutations increase Cdk5-mediated phosphorylation of neurofilaments von Holmgren, Anne, Bouhy, Delphine, De Winter, Vicky, Asselbergh, Bob, Timmermans, Jean-Pierre, Irobi, Joy, Timmerman, Vincent

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Increased Monomerization of Mutant HSPB1 Leads to Protein Hyperactivity in Charcot-Marie-Tooth Neuropathy von Almeida-Souza, Leonardo, Goethals, Sofie, de Winter, Vicky, Dierick, Ines, Gallardo, Rodrigo, Van Durme, Joost, Irobi, Joy, Gettemans, Jan, Rousseau, Frederic, Schymkowitz, Joost, Timmerman, Vincent, Janssens, Sophie

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Extracellular vesicle-associated small heat shock proteins as therapeutic agents in neurodegenerative diseases and beyond von Van den Broek, Bram, Wuyts, Charlotte, Irobi, Joy

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Mutant HSPB8 causes protein aggregates and a reduced mitochondrial membrane potential in dermal fibroblasts from distal hereditary motor neuropathy patients von Irobi, Joy, Holmgren, Anne, Winter, Vicky De, Asselbergh, Bob, Gettemans, Jan, Adriaensen, Dirk, Groote, Chantal Ceuterick-de, Coster, Rudy Van, Jonghe, Peter De, Timmerman, Vincent

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Small heat shock proteins in inherited peripheral neuropathies von Dierick, Ines, Irobi, Joy, De Jonghe, Peter, Timmerman, Vincent

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Extracellular vesicle-associated lipids in central nervous system disorders von Vanherle, Sam, Haidar, Mansour, Irobi, Joy, Bogie, Jeroen F.J., Hendriks, Jerome J.A.

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Molecular Defects in the Motor Adaptor BICD2 Cause Proximal Spinal Muscular Atrophy with Autosomal-Dominant Inheritance von Peeters, Kristien, Litvinenko, Ivan, Asselbergh, Bob, Almeida-Souza, Leonardo, Chamova, Teodora, Geuens, Thomas, Ydens, Elke, Zimoń, Magdalena, Irobi, Joy, De Vriendt, Els, De Winter, Vicky, Ooms, Tinne, Timmerman, Vincent, Tournev, Ivailo, Jordanova, Albena

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Small heat-shock protein HSPB1 mutants stabilize microtubules in Charcot-Marie-Tooth neuropathy von Almeida-Souza, Leonardo, Asselbergh, Bob, d'Ydewalle, Constantin, Moonens, Kristof, Goethals, Sofie, de Winter, Vicky, Azmi, Abdelkrim, Irobi, Joy, Timmermans, Jean-Pierre, Gevaert, Kris, Remaut, Han, Van Den Bosch, Ludo, Timmerman, Vincent, Janssens, Sophie

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Mutant HSPB8 causes motor neuron-specific neurite degeneration von Irobi, Joy, Almeida-Souza, Leonardo, Asselbergh, Bob, De Winter, Vicky, Goethals, Sofie, Dierick, Ines, Krishnan, Jyothsna, Timmermans, Jean-Pierre, Robberecht, Wim, De Jonghe, Peter, Van Den Bosch, Ludo, Janssens, Sophie, Timmerman, Vincent

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Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy von Irobi, Joy, Impe, Katrien Van, Seeman, Pavel, Jordanova, Albena, Dierick, Ines, Verpoorten, Nathalie, Michalik, Andrej, Vriendt, Els De, Jacobs, An, Gerwen, Veerle Van, Vennekens, Krist'l, Mazanec, Radim, Tournev, Ivailo, Hilton-Jones, David, Talbot, Kevin, Kremensky, Ivo, Bosch, Ludo Van Den, Robberecht, Wim, Vandekerckhove, Joël, Broeckhoven, Christine Van, Gettemans, Jan, Jonghe, Peter De, Timmerman, Vincent

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Molecular genetics of distal hereditary motor neuropathies von Irobi, Joy, De Jonghe, Peter, Timmerman, Vincent

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Microglial derived extracellular vesicles activate autophagy and mediate multi‐target signaling to maintain cellular homeostasis von Van den Broek, Bram, Pintelon, Isabel, Hamad, Ibrahim, Kessels, Sofie, Haidar, Mansour, Hellings, Niels, Hendriks, Jerome J.A., Kleinewietfeld, Markus, Brône, Bert, Timmerman, Vincent, Timmermans, Jean‐Pierre, Somers, Veerle, Michiels, Luc, Irobi, Joy

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Heterozygous missense mutations in BSCL2 are associated with distal hereditary motor neuropathy and Silver syndrome von Windpassinger, Christian, Auer-Grumbach, Michaela, Irobi, Joy, Patel, Heema, Petek, Erwin, Hörl, Gerd, Malli, Roland, Reed, Johanna A, Dierick, Ines, Verpoorten, Nathalie, Warner, Thomas T, Proukakis, Christos, den Bergh, Peter Van, Verellen, Christine, Maldergem, Lionel Van, Merlini, Luciano, Jonghe, Peter De, Timmerman, Vincent, Crosby, Andrew H, Wagner, Klaus

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