Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ von Iredale, John P

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Extracellular matrix degradation in liver fibrosis: Biochemistry and regulation von Iredale, John P., Thompson, Alexandra, Henderson, Neil C.

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Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease von Boulter, Luke, Govaere, Olivier, Bird, Tom G, Radulescu, Sorina, Ramachandran, Prakash, Pellicoro, Antonella, Ridgway, Rachel A, Seo, Sang Soo, Spee, Bart, Van Rooijen, Nico, Sansom, Owen J, Iredale, John P, Lowell, Sally, Roskams, Tania, Forbes, Stuart J

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Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis von Ramachandran, Prakash, Pellicoro, Antonella, Vernon, Madeleine A., Boulter, Luke, Aucott, Rebecca L., Ali, Aysha, Hartland, Stephen N., Snowdon, Victoria K., Cappon, Andrea, Gordon-Walker, Timothy T., Williams, Mike J., Dunbar, Donald R., Manning, Jonathan R., van Rooijen, Nico, Fallowfield, Jonathan A., Forbes, Stuart J., Iredale, John P.

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Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells von Schrader, Jörg, Gordon‐Walker, Timothy T., Aucott, Rebecca L., van Deemter, Mariëlle, Quaas, Alexander, Walsh, Shaun, Benten, Daniel, Forbes, Stuart J., Wells, Rebecca G., Iredale, John P.

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Galectin-3 Expression and Secretion Links Macrophages to the Promotion of Renal Fibrosis von Henderson, Neil C, Mackinnon, Alison C, Farnworth, Sarah L, Kipari, Tiina, Haslett, Christopher, Iredale, John P, Liu, Fu-Tong, Hughes, Jeremy, Sethi, Tariq

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Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function von Thomas, James A., Pope, Caroline, Wojtacha, Davina, Robson, Andrew J., Gordon‐Walker, Timothy T., Hartland, Stephen, Ramachandran, Prakash, Van Deemter, Marielle, Hume, David A., Iredale, John P., Forbes, Stuart J.

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The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury von Campana, Lara, Starkey Lewis, Philip J, Pellicoro, Antonella, Aucott, Rebecca L, Man, Janet, O'Duibhir, Eoghan, Mok, Sarah E, Ferreira-Gonzalez, Sofia, Livingstone, Eilidh, Greenhalgh, Stephen N, Hull, Katherine L, Kendall, Timothy J, Vernimmen, Douglas, Henderson, Neil C, Boulter, Luke, Gregory, Christopher D, Feng, Yi, Anderton, Stephen M, Forbes, Stuart J, Iredale, John P

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An efficient method to isolate Kupffer cells eliminating endothelial cell contamination and selective bias von Lynch, Ruairi W., Hawley, Catherine A., Pellicoro, Antonella, Bain, Calum C., Iredale, John P., Jenkins, Stephen J.

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Liver fibrosis and repair: immune regulation of wound healing in a solid organ von Pellicoro, Antonella, Ramachandran, Prakash, Iredale, John P., Fallowfield, Jonathan A.

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Scar-Associated Macrophages Are a Major Source of Hepatic Matrix Metalloproteinase-13 and Facilitate the Resolution of Murine Hepatic Fibrosis von Fallowfield, Jonathan A, Mizuno, Masashi, Kendall, Timothy J, Constandinou, Christothea M, Benyon, R. Christopher, Duffield, Jeremy S, Iredale, John P

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Generation of functional human hepatic endoderm from human induced pluripotent stem cells von Sullivan, Gareth J., Hay, David C., Park, In‐Hyun, Fletcher, Judy, Hannoun, Zara, Payne, Catherine M., Dalgetty, Donna, Black, James R., Ross, James A., Samuel, Kay, Wang, Gang, Daley, George Q., Lee, Je‐Hyuk, Church, George M., Forbes, Stuart J., Iredale, John P., Wilmut, Ian

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Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling von Bird, Thomas G., Lu, Wei-Yu, Boulter, Luke, Gordon-Keylock, Sabrina, Ridgway, Rachel A., Williams, Michael J., Taube, Jessica, Thomas, James A., Wojtacha, Davina, Gambardella, Adriana, Sansom, Owen J., Iredale, John P., Forbes, Stuart J.

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Galectin-3 Regulates Myofibroblast Activation and Hepatic Fibrosis von Henderson, Neil C., Mackinnon, Alison C., Farnworth, Sarah L., Poirier, Francoise, Russo, Francesco P., Iredale, John P., Haslett, Christopher, Simpson, Kenneth J., Sethi, Tariq

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Elastin accumulation is regulated at the level of degradation by macrophage metalloelastase (MMP-12) during experimental liver fibrosis von Pellicoro, Antonella, Aucott, Rebecca L., Ramachandran, Prakash, Robson, Andrew J., Fallowfield, Jonathan A., Snowdon, Victoria K., Hartland, Stephen N., Vernon, Madeleine, Duffield, Jeremy S., Benyon, R. Christopher, Forbes, Stuart J., Iredale, John P.

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Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling von Hay, David C, Fletcher, Judy, Payne, Catherine, Terrace, John D, Gallagher, Ronald C.J, Snoeys, Jan, Black, James R, Wojtacha, Davina, Samuel, Kay, Hannoun, Zara, Pryde, Anne, Filippi, Celine, Currie, Ian S, Forbes, Stuart J, Ross, James A, Newsome, Philip N, Iredale, John P

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The Bone Marrow Functionally Contributes to Liver Fibrosis von Russo, Francesco P., Alison, Malcolm R., Bigger, Brian W., Amofah, Eunice, Florou, Aikaterini, Amin, Farhana, Bou–Gharios, George, Jeffery, Rosemary, Iredale, John P., Forbes, Stuart J.

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Kynurenine monooxygenase regulates inflammation during critical illness and recovery in experimental acute pancreatitis von Hayes, Alastair J., Zheng, Xiaozhong, O’Kelly, James, Neyton, Lucile P.A., Bochkina, Natalia A., Uings, Iain, Liddle, John, Baillie, J. Kenneth, Just, George, Binnie, Margaret, Homer, Natalie Z.M., Murray, Toby B.J., Baily, James, McGuire, Kris, Skouras, Christos, Garden, O. James, Webster, Scott P., Iredale, John P., Howie, Sarah E.M., Mole, Damian J.

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Reversibility of liver fibrosis von Ramachandran, Prakash, Iredale, John P

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Accurate Prediction of Drug‐Induced Liver Injury Using Stem Cell‐Derived Populations von Szkolnicka, Dagmara, Farnworth, Sarah L., Lucendo-Villarin, Baltasar, Storck, Christopher, Zhou, Wenli, Iredale, John P., Flint, Oliver, Hay, David C.

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