Use of differentiated pluripotent stem cells as replacement therapy for treating disease von Fox, Ira J., Daley, George Q., Goldman, Steven A., Huard, Johnny, Kamp, Timothy J., Trucco, Massimo

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Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells von Takeishi, Kazuki, Collin de l’Hortet, Alexandra, Wang, Yang, Handa, Kan, Guzman-Lepe, Jorge, Matsubara, Kentaro, Morita, Kazutoyo, Jang, Sae, Haep, Nils, Florentino, Rodrigo M., Yuan, Fangchao, Fukumitsu, Ken, Tobita, Kimimasa, Sun, Wendell, Franks, Jonathan, Delgado, Evan R., Shapiro, Erik M., Fraunhoffer, Nicolas A., Duncan, Andrew W., Yagi, Hiroshi, Mashimo, Tomoji, Fox, Ira J., Soto-Gutierrez, Alejandro

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Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism von Collin de l’Hortet, Alexandra, Takeishi, Kazuki, Guzman-Lepe, Jorge, Morita, Kazutoyo, Achreja, Abhinav, Popovic, Branimir, Wang, Yang, Handa, Kan, Mittal, Anjali, Meurs, Noah, Zhu, Ziwen, Weinberg, Frank, Salomon, Michael, Fox, Ira J., Deng, Chu-Xia, Nagrath, Deepak, Soto-Gutierrez, Alejandro

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Resetting the transcription factor network reverses terminal chronic hepatic failure von Nishikawa, Taichiro, Bell, Aaron, Brooks, Jenna M, Setoyama, Kentaro, Melis, Marta, Han, Bing, Fukumitsu, Ken, Handa, Kan, Tian, Jianmin, Kaestner, Klaus H, Vodovotz, Yoram, Locker, Joseph, Soto-Gutierrez, Alejandro, Fox, Ira J

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A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease von Nishikawa, Taichiro, Bellance, Nadège, Damm, Aaron, Bing, Han, Zhu, Zhen, Handa, Kan, Yovchev, Mladen I, Sehgal, Vasudha, Moss, Tyler J, Oertel, Michael, Ram, Prahlad T, Pipinos, Iraklis I, Soto-Gutierrez, Alejandro, Fox, Ira J, Nagrath, Deepak

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Differentiation and Transplantation of Human Embryonic Stem Cell–Derived Hepatocytes von Basma, Hesham, Soto–Gutiérrez, Alejandro, Yannam, Govardhana Rao, Liu, Liping, Ito, Ryotaro, Yamamoto, Toshiyuki, Ellis, Ewa, Carson, Steven D, Sato, Shintaro, Chen, Yong, Muirhead, David, Navarro–Álvarez, Nalu, Wong, Ronald J, Roy–Chowdhury, Jayanta, Platt, Jeffrey L, Mercer, David F, Miller, John D, Strom, Stephen C, Kobayashi, Naoya, Fox, Ira J

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Induced pluripotent stem cells model personalized variations in liver disease resulting from α1‐antitrypsin deficiency von Tafaleng, Edgar N., Chakraborty, Souvik, Han, Bing, Hale, Pamela, Wu, Wanquan, Soto‐Gutierrez, Alejandro, Feghali‐Bostwick, Carol A., Wilson, Andrew A., Kotton, Darrell N., Nagaya, Masaki, Strom, Stephen C., Roy‐Chowdhury, Jayanta, Stolz, Donna B., Perlmutter, David H., Fox, Ira J.

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Liver transplantation for pediatric metabolic disease von Mazariegos, George, Shneider, Benjamin, Burton, Barbara, Fox, Ira J., Hadzic, Nedim, Kishnani, Priya, Morton, D. Holmes, Mcintire, Sara, Sokol, Ronald J., Summar, Marshall, White, Desiree, Chavanon, Vincent, Vockley, Jerry

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Amelioration of Hyperbilirubinemia in Gunn Rats after Transplantation of Human Induced Pluripotent Stem Cell-Derived Hepatocytes von Chen, Yong, Li, Yanfeng, Wang, Xia, Zhang, Wei, Sauer, Vanessa, Chang, Chan-Jung, Han, Bing, Tchaikovskaya, Tatyana, Avsar, Yesim, Tafaleng, Edgar, Madhusudana Girija, Sanal, Tar, Krisztina, Polgar, Zsuzsanna, Strom, Stephen, Bouhassira, Eric E., Guha, Chandan, Fox, Ira J., Roy-Chowdhury, Jayanta, Roy-Chowdhury, Namita

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Improving the Techniques for Human Hepatocyte Transplantation: Report from a Consensus Meeting in London von Puppi, Juliana, Strom, Stephen C., Hughes, Robin D., Bansal, Sanjay, Castell, Jose V., Dagher, Ibrahim, Ellis, Ewa C. S., Nowak, Greg, Ericzon, Bo-Goran, Fox, Ira J., Gómez-Lechón, M. José, Guha, Chandan, Gupta, Sanjeev, Mitry, Ragai R., Ohashi, Kazuo, Ott, Michael, Reid, Lola M., Roy-Chowdhury, Jayanta, Sokal, Etienne, Weber, Anne, Dhawan, Anil

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Barriers to the successful treatment of liver disease by hepatocyte transplantation von Soltys, Kyle A, Soto-Gutiérrez, Alejandro, Nagaya, Masaki, Baskin, Kevin M, Deutsch, Melvin, Ito, Ryotaro, Shneider, Benjamin L, Squires, Robert, Vockley, Jerry, Guha, Chandan, Roy-Chowdhury, Jayanta, Strom, Stephen C, Platt, Jeffrey L, Fox, Ira J

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Mechanism and Effect of HNF4α Decrease in a Rat Model of Cirrhosis and Liver Failure von Melis, Marta, Marino, Rebecca, Tian, Jianmin, Johnson, Carla, Sethi, Rahil, Oertel, Michael, Fox, Ira J., Locker, Joseph

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Single liver lobe repopulation with wildtype hepatocytes using regional hepatic irradiation cures jaundice in Gunn rats von Zhou, Hongchao, Dong, Xinyuan, Kabarriti, Rafi, Chen, Yong, Avsar, Yesim, Wang, Xia, Ding, Jianqiang, Liu, Laibin, Fox, Ira J, Roy-Chowdhury, Jayanta, Roy-Chowdhury, Namita, Guha, Chandan

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A Whole-Organ Regenerative Medicine Approach for Liver Replacement von Soto-Gutierrez, Alejandro, Zhang, Li, Medberry, Chris, Fukumitsu, Ken, Faulk, Denver, Jiang, Hongbin, Reing, Janet, Gramignoli, Roberto, Komori, Junji, Ross, Mark, Nagaya, Masaki, Lagasse, Eric, Stolz, Donna, Strom, Stephen C., Fox, Ira J., Badylak, Stephen F.

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Induced pluripotent stem cells model personalized variations in liver disease resulting from [alpha]1-antitrypsin deficiency von Tafaleng, Edgar N, Chakraborty, Souvik, Han, Bing, Hale, Pamela, Wu, Wanquan, Soto-Gutierrez, Alejandro, Feghali-Bostwick, Carol A, Wilson, Andrew A, Kotton, Darrell N, Nagaya, Masaki, Strom, Stephen C, Roy-Chowdhury, Jayanta, Stolz, Donna B, Perlmutter, David H, Fox, Ira J

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Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes von Tanaka, Kimiaki, Narushima, Michiki, Rivas-Carrillo, Jorge David, Navarro-Álvarez, Nalu, Basma, Hesham, Yoon, Ji-Won, Fox, Ira J, Soto-Gutiérrez, Alejandro, Miki, Atsushi, Lebkowski, Jane, Kobayashi, Naoya, Okitsu, Teru, Tabata, Yashuhiko, Tanaka, Noriaki, Chen, Yong, Jun, Hee-Sook, Zhao, Debaio, Ueda, Tadayoshi, Noguchi, Hirofumi

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Human Urinary Epithelial Cells as a Source of Engraftable Hepatocyte-Like Cells Using Stem Cell Technology von Sauer, Vanessa, Tchaikovskaya, Tatyana, Wang, Xia, Li, Yanfeng, Zhang, Wei, Tar, Krisztina, Polgar, Zsuzsanna, Ding, Jianqiang, Guha, Chandan, Fox, Ira J., Roy-Chowdhury, Namita, Roy-Chowdhury, Jayanta

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Redefining Spinal Cord Stimulation “Trials”: A Randomized Controlled Trial Using Single‐Stage Wireless Permanent Implantable Devices von North, Richard B., Calodney, Aaron, Bolash, Robert, Slavin, Konstantin V., Creamer, Michael, Rauck, Richard, Vahedifar, Payam, Fox, Ira, Özaktay, Cuneyt, Panchal, Sunil, Vanquathem, Niek

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Hepatic irradiation augments engraftment of donor cells following hepatocyte transplantation von Yamanouchi, Kosho, Zhou, Hongchao, Roy‐Chowdhury, Namita, Macaluso, Frank, Liu, Liping, Yamamoto, Toshiyuki, Yannam, Govardhana Rao, Enke, Charles, Solberg, Timothy D., Adelson, Anthony B., Platt, Jeffrey L., Fox, Ira J., Roy‐Chowdhury, Jayanta, Guha, Chandan

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Rapid and Sensitive Assessment of Human Hepatocyte Functions von Gramignoli, Roberto, Tahan, Veysel, Dorko, Kenneth, Venkataramanan, Raman, Fox, Ira J., Ellis, Ewa C. S., Vosough, Massoud, Strom, Stephen C.

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