Apparent activity in high-throughput screening: origins of compound-dependent assay interference von Thorne, Natasha, Auld, Douglas S, Inglese, James

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Quantitative High-Throughput Screening: A Titration-Based Approach That Efficiently Identifies Biological Activities in Large Chemical Libraries von Inglese, James, Auld, Douglas S., Jadhav, Ajit, Johnson, Ronald L., Simeonov, Anton, Yasgar, Adam, Zheng, Wei, Austin, Christopher P.

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High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells von Schmitt, Danielle L, Dranchak, Patricia, Parajuli, Prakash, Blivis, Dvir, Voss, Ty, Kohnhorst, Casey L, Kyoung, Minjoung, Inglese, James, An, Songon

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High-throughput screening assays for the identification of chemical probes von Inglese, James, Johnson, Ronald L, Simeonov, Anton, Xia, Menghang, Zheng, Wei, Austin, Christopher P, Auld, Douglas S

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Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries von Veith, Henrike, Lloyd, David G, Inglese, James, Southall, Noel, James, Tim, Fayne, Darren, Auld, Douglas S, Huang, Ruili, Artemenko, Natalia, Shen, Min, Austin, Christopher P

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High-Throughput Screening to Identify Inhibitors of the Type I Interferon–Major Histocompatibility Complex Class I Pathway in Skeletal Muscle von Kinder, Travis B, Dranchak, Patricia K, Inglese, James

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Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression von Auld, Douglas S, Thorne, Natasha, Maguire, William F, Inglese, James

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A High-Throughput Screen for Aggregation-Based Inhibition in a Large Compound Library von Feng, Brian Y, Simeonov, Anton, Jadhav, Ajit, Babaoglu, Kerim, Inglese, James, Shoichet, Brian K, Austin, Christopher P

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Identification of oxadiazoles as new drug leads for the control of schistosomiasis von Austin, Christopher P, Williams, David L, Sayed, Ahmed A, Simeonov, Anton, Thomas, Craig J, Inglese, James

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In vivo quantitative high-throughput screening for drug discovery and comparative toxicology von Dranchak, Patricia K, Oliphant, Erin, Queme, Bryan, Lamy, Laurence, Wang, Yuhong, Huang, Ruili, Xia, Menghang, Tao, Dingyin, Inglese, James

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Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors von Miller, Thomas W, Amason, Joshua D, Garcin, Elsa D, Lamy, Laurence, Dranchak, Patricia K, Macarthur, Ryan, Braisted, John, Rubin, Jeffrey S, Burgess, Teresa L, Farrell, Catherine L, Roberts, David D, Inglese, James

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Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases von Yu, Hao, Dranchak, Patricia, Li, Zhiru, MacArthur, Ryan, Munson, Matthew S., Mehzabeen, Nurjahan, Baird, Nathan J., Battalie, Kevin P., Ross, David, Lovell, Scott, Carlow, Clotilde K. S., Suga, Hiroaki, Inglese, James

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qHTSWaterfall: 3-dimensional visualization software for quantitative high-throughput screening (qHTS) data von Queme, Bryan, Braisted, John C., Dranchak, Patricia, Inglese, James

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Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124 von Auld, Douglas S, Lovell, Scott, Thorne, Natasha, Lea, Wendy A, Maloney, David J, Shen, Min, Rai, Ganesha, Battaile, Kevin P, Thomas, Craig J, Simeonov, Anton, Hanzlik, Robert P, Inglese, James

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ICE1 promotes the link between splicing and nonsense-mediated mRNA decay von Baird, Thomas D, Cheng, Ken Chih-Chien, Chen, Yu-Chi, Buehler, Eugen, Martin, Scott E, Inglese, James, Hogg, J Robert

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High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations von Mott, Bryan T., Eastman, Richard T., Guha, Rajarshi, Sherlach, Katy S., Siriwardana, Amila, Shinn, Paul, McKnight, Crystal, Michael, Sam, Lacerda-Queiroz, Norinne, Patel, Paresma R., Khine, Pwint, Sun, Hongmao, Kasbekar, Monica, Aghdam, Nima, Fontaine, Shaun D., Liu, Dongbo, Mierzwa, Tim, Mathews-Griner, Lesley A., Ferrer, Marc, Renslo, Adam R., Inglese, James, Yuan, Jing, Roepe, Paul D., Su, Xin-zhuan, Thomas, Craig J.

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Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening von Xia, Menghang, Huang, Ruili, Witt, Kristine L., Southall, Noel, Fostel, Jennifer, Cho, Ming-Hsuang, Jadhav, Ajit, Smith, Cynthia S., Inglese, James, Portier, Christopher J., Tice, Raymond R., Austin, Christopher P.

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A homogeneous SIRPα-CD47 cell-based, ligand-binding assay: Utility for small molecule drug development in immuno-oncology von Burgess, Teresa L, Amason, Joshua D, Rubin, Jeffrey S, Duveau, Damien Y, Lamy, Laurence, Roberts, David D, Farrell, Catherine L, Inglese, James, Thomas, Craig J, Miller, Thomas W

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Rapid RNA–ligand interaction analysis through high-information content conformational and stability landscapes von Baird, Nathan J., Inglese, James, Ferré-D’Amaré, Adrian R.

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Characterization of Chemical Libraries for Luciferase Inhibitory Activity von Auld, Douglas S, Southall, Noel T, Jadhav, Ajit, Johnson, Ronald L, Diller, David J, Simeonov, Anton, Austin, Christopher P, Inglese, James

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