Binding Affinities of Factor Xa Inhibitors Estimated by Thermodynamic Integration and MM/GBSA von Genheden, Samuel, Nilsson, Ingemar, Ryde, Ulf

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Appendectomy versus Antibiotic Treatment in Acute Appendicitis. A Prospective Multicenter Randomized Controlled Trial von Styrud, Johan, Eriksson, Staffan, Nilsson, Ingemar, Ahlberg, Gunnar, Haapaniemi, Staffan, Neovius, Gunnar, Rex, Lars, Badume, Ibrahim, Granström, Lars

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Creating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug design von Fjellström, Ola, Akkaya, Sibel, Beisel, Hans-Georg, Eriksson, Per-Olof, Erixon, Karl, Gustafsson, David, Jurva, Ulrik, Kang, Daiwu, Karis, David, Knecht, Wolfgang, Nerme, Viveca, Nilsson, Ingemar, Olsson, Thomas, Redzic, Alma, Roth, Robert, Sandmark, Jenny, Tigerström, Anna, Öster, Linda

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3D-Lab: a collaborative web-based platform for molecular modeling von Grebner, Christoph, Norrby, Magnus, Enström, Jonatan, Nilsson, Ingemar, Hogner, Anders, Henriksson, Jonas, Westin, Johan, Faramarzi, Farzad, Werner, Philip, Boström, Jonas

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Synthesis and SAR of Thrombin Inhibitors Incorporating a Novel 4-Amino-Morpholinone Scaffold:  Analysis of X-ray Crystal Structure of Enzyme Inhibitor Complex von Nilsson, Jonas W, Kvarnström, Ingemar, Musil, Djordje, Nilsson, Ingemar, Samulesson, Bertil

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Synthesis of Novel Thrombin Inhibitors. Use of Ring-Closing Metathesis Reactions for Synthesis of P2 Cyclopentene- and Cyclohexenedicarboxylic Acid Derivatives von Thorstensson, Fredrik, Kvarnström, Ingemar, Musil, Djordje, Nilsson, Ingemar, Samuelsson, Bertil

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Ligand Affinities Predicted with the MM/PBSA Method:  Dependence on the Simulation Method and the Force Field von Weis, Aaron, Katebzadeh, Kambiz, Söderhjelm, Pär, Nilsson, Ingemar, Ryde, Ulf

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Investigation of the Relationship between Topology and Selectivity for Druglike Molecules von Yang, Yidong, Chen, Hongming, Nilsson, Ingemar, Muresan, Sorel, Engkvist, Ola

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Beyond the Scope of Free-Wilson Analysis: Building Interpretable QSAR Models with Machine Learning Algorithms von Chen, Hongming, Carlsson, Lars, Eriksson, Mats, Varkonyi, Peter, Norinder, Ulf, Nilsson, Ingemar

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A new oral anticoagulant: the 50-year challenge von Gustafsson, David, Bylund, Ruth, Antonsson, Thomas, Nilsson, Ingemar, Nyström, Jan-Erik, Eriksson, Ulf, Bredberg, Ulf, Teger-Nilsson, Ann-Catrine

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Composite multi-parameter ranking of real and virtual compounds for design of MC4R agonists: Renaissance of the Free-Wilson methodology von Nilsson, Ingemar, Polla, Magnus O.

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Beyond the Scope of Free-Wilson Analysis. 2: Can Distance Encoded R‑Group Fingerprints Provide Interpretable Nonlinear Models? von Eriksson, Mats, Chen, Hongming, Carlsson, Lars, Nissink, J. Willem M, Cumming, John G, Nilsson, Ingemar

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Design, synthesis, and thrombin-inhibitory activity of pyridin-2-ones as P 2/P 3 core motifs von Hanessian, Stephen, Simard, Daniel, Bayrakdarian, Malken, Therrien, Eric, Nilsson, Ingemar, Fjellström, Ola

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Design, synthesis, and thrombin-inhibitory activity of pyridin-2-ones as P2/P3 core motifs von HANESSIAN, Stephen, SIMARD, Daniel, BAYRAKDARIAN, Malken, THERRIEN, Eric, NILSSON, Ingemar, FJELLSTRÖM, Ola

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A latch mechanism and a detachable part equipped with such a latch mechanism for modular scaffolding von Nilsson, Ingemar

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Targeting thrombin and factor VIIa: Design, synthesis, and inhibitory activity of functionally relevant indolizidinones von HANESSIAN, Stephen, THERRIEN, Eric, GRANBERG, Kenneth, NILSSON, Ingemar

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SARConnect: A Tool to Interrogate the Connectivity Between Proteins, Chemical Structures and Activity Data von Eriksson, Mats, Nilsson, Ingemar, Kogej, Thierry, Southan, Christopher, Johansson, Martin, Tyrchan, Christian, Muresan, Sorel, Blomberg, Niklas, Bjäreland, Marcus

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Locking device for scaffolding von Nilsson, Ingemar

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From natural products to achiral drug prototypes: Potent thrombin inhibitors based on P 2/P 3 dihydropyrid-2-one core motifs von Hanessian, Stephen, Therrien, Eric, Zhang, Jianbin, Otterlo, Willem van, Xue, Yafeng, Gustafsson, David, Nilsson, Ingemar, Fjellström, Ola

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From natural products to achiral drug prototypes: Potent thrombin inhibitors based on P2/P3 dihydropyrid-2-one core motifs von HANESSIAN, Stephen, THERRIEN, Eric, JIANBIN ZHANG, VAN OTTERLO, Willem, YAFENG XUE, GUSTAFSSON, David, NILSSON, Ingemar, FJELLSTRÖM, Ola

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